LOCUS       NM_001400626            2505 bp    mRNA    linear   ROD 12-JUN-2023
DEFINITION  Rattus norvegicus RecQ mediated genome instability 1 (Rmi1),
            transcript variant 1, mRNA.
ACCESSION   NM_001400626 XM_225150
VERSION     NM_001400626.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2505)
  AUTHORS   Suwa A, Yoshino M, Yamazaki C, Naitou M, Fujikawa R, Matsumoto S,
            Kurama T, Shimokawa T and Aramori I.
  TITLE     RMI1 deficiency in mice protects from diet and genetic-induced
            obesity
  JOURNAL   FEBS J 277 (3), 677-686 (2010)
   PUBMED   20050919
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JACYVU010000284.1.
            
            On Jan 26, 2022 this sequence version replaced XM_225150.9.
            
            ##Evidence-Data-START##
            Transcript exon combination :: FN801388.1, FN801387.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132299, SAMEA5760383
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-235               JACYVU010000284.1  6263589-6263823     c
            236-320             JACYVU010000284.1  6259667-6259751     c
            321-2505            JACYVU010000284.1  6256533-6258717     c
FEATURES             Location/Qualifiers
     source          1..2505
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="17"
                     /map="17p14"
     gene            1..2505
                     /gene="Rmi1"
                     /gene_synonym="RGD1310671"
                     /note="RecQ mediated genome instability 1"
                     /db_xref="GeneID:306734"
                     /db_xref="RGD:1310671"
     exon            1..235
                     /gene="Rmi1"
                     /gene_synonym="RGD1310671"
                     /inference="alignment:Splign:2.1.0"
     exon            236..320
                     /gene="Rmi1"
                     /gene_synonym="RGD1310671"
                     /inference="alignment:Splign:2.1.0"
     misc_feature    302..304
                     /gene="Rmi1"
                     /gene_synonym="RGD1310671"
                     /note="upstream in-frame stop codon"
     exon            321..2505
                     /gene="Rmi1"
                     /gene_synonym="RGD1310671"
                     /inference="alignment:Splign:2.1.0"
     CDS             350..2203
                     /gene="Rmi1"
                     /gene_synonym="RGD1310671"
                     /note="RMI1, RecQ mediated genome instability 1, homolog"
                     /codon_start=1
                     /product="recQ-mediated genome instability protein 1"
                     /protein_id="NP_001387555.1"
                     /db_xref="GeneID:306734"
                     /db_xref="RGD:1310671"
                     /translation="

MSVASAVLRVETWLLATWNIKVPLMWLEACVNWIQEENNSANLSQAQINKQVLEQWLLTDLRDLEHPLLPDDILEIPKGELNGFYALQINSLVDVSQPAYSQIQKLRGKSTTNDLVSAETQTAPEPWQVRPSRMLMLQLTDGVTQVQGMEYQSIPALHSALPPGTKILVHGHILFRLGVLLLKAENVKVLGGEVDGLAEEYAQEKILARLIGEPDPTVSVIPNNSNPSAPRVSGDLDAALGPSDEELLASLDESEEPAASDDVTVGRLSFSTGPSSDTAPTIQTGFEPGCNISSRPKEKLPNQPVHFTDGEFDDFSLEEALLLEETVQKEKMEAKASQPLSLKESVGKRVEEAFSPRPGGLNHTASTHKQGNSHFSEKTSEQMIHEDTLFDCSSTRHHRKRLLAHDFTKDSKISEVDDVAQQTTNSSDVHCLSNKMLNRKPDLSEKSSQHSKGNGHPFQTCSSRSFENNTNLSIGMDLHCPPFIYLSVLMARKPKEVTTVKVKAFIVTLTGNLSSSGGFWCVTAKVSDGTAYLDVDFIDEILTSMIGYSVPEMKQLKKDPLKYKKFLEGLQKCQRDLIDLCCLMTVSYDPSSCKGMVLELQDVGVEHLENLKKRLNK"

     misc_feature    389..961
                     /gene="Rmi1"
                     /gene_synonym="RGD1310671"
                     /note="RecQ mediated genome instability protein; Region:
                     RMI1_N; pfam08585"
                     /db_xref="CDD:430090"
     misc_feature    1790..2182
                     /gene="Rmi1"
                     /gene_synonym="RGD1310671"
                     /note="Recq-mediated genome instability protein 1,
                     C-terminal OB-fold; Region: RMI1_C; pfam16099"
                     /db_xref="CDD:435136"
ORIGIN      

gctgctcacgtgtgcggggaaagggggcggccgcgggggattttcgagccccgagggagttgggcgggggctggaggaggaggagggacgcccgagcgcggcggattgggcgggaagaagtgaaaagagaggggaagagaaaaccctaggaacaggaaagggagagcaccgggcggcgcgcggccccgggatcacgctactgccgctgtcgtgcgaggcgaggcggcaaggccagagtcatttctctgcagaagaggctttgagtactgaccatccagcgtgaaatccggtcattagatcttaggctgtcctgctaagtggtggatgtggatgctcctatttaaaagaaatgagtgtagctagtgctgtattaagagtcgaaacctggcttttggcaacatggaatattaaagtgcctctgatgtggctggaagcttgtgttaactggatccaagaagaaaataatagtgctaacttgagtcaggcacaaataaataagcaagtgttagagcaatggcttcttactgacctgagagacctggaacatcctctcttacctgatgacattttagaaattccaaagggagaactgaatgggttttatgctctacagatcaattccttggttgacgtaagtcagcctgcgtattcccagatacaaaagctgagaggaaagagtacaaccaatgatctagtgtcagcggaaacgcagacggccccagagccatggcaagtaaggccttctcggatgctgatgctgcagctcactgacggtgtcacacaagtccaggggatggaataccagtctattcccgctctccacagtgctcttcctccaggtacaaagatcctagttcatgggcacattttgttccgccttggtgttctcttactgaaggcagaaaacgtgaaggtgctaggaggggaggtagatggtcttgcagaagaatatgcccaagagaaaatacttgcaagattaattggagaacctgaccctacagtttcagtcattccaaataattctaatcccagcgcgcccagagtttcaggggatttagatgctgctttggggccttcagacgaagaactcttggcaagccttgatgaaagtgaagagcctgcagcaagtgatgatgtgacggtggggagactcagcttcagcacaggcccttcctcagatactgccccaacaattcagactggttttgagccgggatgtaatatttcttcaaggccaaaggagaaactaccaaaccagcctgtgcatttcactgatggagaatttgatgacttttccctggaagaggccttgcttttggaagaaacggtccagaaagagaaaatggaagcaaaagcatcacagccactgagtttgaaggagagcgtgggtaaacgtgtggaggaggccttctcacctagacctgggggtctgaaccacacagcctcgactcataaacaaggaaacagccacttcagtgagaaaacatctgaacagatgatccatgaagacacactttttgactgttcatctactagacaccatcgtaagagactcttagctcatgattttacaaaagacagtaagatttcagaagtagatgatgtagcacaacaaaccaccaacagttcagatgtacattgcttaagtaataaaatgttaaacaggaagccggacctatcagagaagagttcacaacattctaaaggaaatggccaccctttccagacttgttcttcaagatcatttgagaataatactaacctatctattggcatggacttacactgtccaccctttatctatttgtctgttctaatggccagaaagccaaaggaagttaccactgtgaaagtcaaagcatttattgtcactttaactggaaatctctcaagttccggtggcttttggtgtgtgactgcaaaggtttctgatggtactgcatatctagatgtagattttatagatgaaatacttaccagtatgatagggtattcagtaccagaaatgaaacagttaaaaaaggaccctcttaaatataaaaaattcctagaagggttacaaaaatgccagcgagatctgatagatttgtgttgcctaatgactgtttcatatgatccgtcttcgtgtaaaggcatggtactggaattgcaagatgttggtgtggaacacctcgagaacctaaagaagcggttgaataaataattgccagaatactattggagcacacttttaaaacaggcaaatatttggaatcaaatttgtttgttctcaattttggaattctgtaaaagaaaaagcttcagagcttaaaaatggctgaggcagctcagtggtggtttctgccaggtgtggtgacctgagtttgatctcctggtcccttgaggcaaaaggagagacccagcttcagcttccagaatctgttgttagtcctctacacaggtagcataggacacacacagttggtaaatgatgtttaaaaataaagatatttaatcaaaaatgta

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