LOCUS       NM_001180882            1512 bp    mRNA    linear   PLN 23-JAN-2026
DEFINITION  Saccharomyces cerevisiae S288C arginyltransferase (ATE1), partial
            mRNA.
ACCESSION   NM_001180882
VERSION     NM_001180882.1
DBLINK      BioProject: PRJNA128
KEYWORDS    RefSeq.
SOURCE      Saccharomyces cerevisiae S288C
  ORGANISM  Saccharomyces cerevisiae S288C
            Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina;
            Saccharomycetes; Saccharomycetales; Saccharomycetaceae;
            Saccharomyces.
REFERENCE   1  (bases 1 to 1512)
  AUTHORS   Engel,S.R., Wong,E.D., Nash,R.S., Aleksander,S., Alexander,M.,
            Douglass,E., Karra,K., Miyasato,S.R., Simison,M., Skrzypek,M.S.,
            Weng,S. and Cherry,J.M.
  TITLE     New data and collaborations at the Saccharomyces Genome Database:
            updated reference genome, alleles, and the Alliance of Genome
            Resources
  JOURNAL   Genetics 220 (4) (2022)
   PUBMED   34897464
REFERENCE   2  (bases 1 to 1512)
  AUTHORS   Tettelin,H., Agostoni Carbone,M.L., Albermann,K., Albers,M.,
            Arroyo,J., Backes,U., Barreiros,T., Bertani,I., Bjourson,A.J.,
            Bruckner,M., Bruschi,C.V., Carignani,G., Castagnoli,L., Cerdan,E.,
            Clemente,M.L., Coblenz,A., Coglievina,M., Coissac,E., Defoor,E.,
            Del Bino,S., Delius,H., Delneri,D., de Wergifosse,P., Dujon,B.,
            Kleine,K. et al.
  TITLE     The nucleotide sequence of Saccharomyces cerevisiae chromosome VII
  JOURNAL   Nature 387 (6632 SUPPL), 81-84 (1997)
   PUBMED   9169869
REFERENCE   3  (bases 1 to 1512)
  AUTHORS   Goffeau,A., Barrell,B.G., Bussey,H., Davis,R.W., Dujon,B.,
            Feldmann,H., Galibert,F., Hoheisel,J.D., Jacq,C., Johnston,M.,
            Louis,E.J., Mewes,H.W., Murakami,Y., Philippsen,P., Tettelin,H. and
            Oliver,S.G.
  TITLE     Life with 6000 genes
  JOURNAL   Science 274 (5287), 546 (1996)
   PUBMED   8849441
REFERENCE   4  (bases 1 to 1512)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2026) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   5  (bases 1 to 1512)
  CONSRTM   Saccharomyces Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2015) Department of Genetics, Stanford
            University, Stanford, CA 94305-5120, USA
  REMARK    Protein update by submitter
REFERENCE   6  (bases 1 to 1512)
  CONSRTM   Saccharomyces Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2012) Department of Genetics, Stanford
            University, Stanford, CA 94305-5120, USA
  REMARK    Protein update by submitter
REFERENCE   7  (bases 1 to 1512)
  CONSRTM   Saccharomyces Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (31-MAR-2011) Department of Genetics, Stanford
            University, Stanford, CA 94305-5120, USA
  REMARK    Sequence update by submitter
REFERENCE   8  (bases 1 to 1512)
  CONSRTM   Saccharomyces Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2009) Department of Genetics, Stanford
            University, Stanford, CA 94305-5120, USA
COMMENT     REVIEWED REFSEQ: This record has been curated by SGD. This record
            is derived from an annotated genomic sequence (NC_001139).
            
            ##Genome-Annotation-Data-START##
            Annotation Provider :: SGD
            Annotation Status   :: Full Annotation
            Annotation Version  :: R64-4-1
            URL                 :: http://www.yeastgenome.org/
            ##Genome-Annotation-Data-END##
            COMPLETENESS: incomplete on both ends.
FEATURES             Location/Qualifiers
     source          1..1512
                     /organism="Saccharomyces cerevisiae S288C"
                     /mol_type="mRNA"
                     /strain="S288C"
                     /db_xref="taxon:559292"
                     /chromosome="VII"
     gene            <1..>1512
                     /gene="ATE1"
                     /locus_tag="YGL017W"
                     /db_xref="GeneID:852867"
     CDS             1..1512
                     /gene="ATE1"
                     /locus_tag="YGL017W"
                     /EC_number="2.3.2.8"
                     /experiment="EXISTENCE:direct assay:GO:0004057
                     arginyl-tRNA--protein transferase activity [PMID:2185248]"
                     /experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
                     [PMID:14562095]"
                     /experiment="EXISTENCE:genetic interaction:GO:0006915
                     apoptotic process [PMID:40818972]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0004057
                     arginyl-tRNA--protein transferase activity [PMID:2185248]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0006915
                     apoptotic process [PMID:40818972]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0071596
                     ubiquitin-dependent protein catabolic process via the
                     N-end rule pathway [PMID:2185248]"
                     /note="Arginyl-tRNA-protein transferase; catalyzes
                     post-translational conjugation of arginine, a
                     destabilizing residue, to the N-termini of acceptor
                     proteins and increasing the degradation of substrates with
                     secondary destabilizing residues Asp and Glu via the N-end
                     rule pathway; mitochondrial translocation in response to
                     oxidative stress induces apoptosis; may play a role in
                     regulating stress response"
                     /codon_start=1
                     /product="arginyltransferase"
                     /protein_id="NP_011498.1"
                     /db_xref="GeneID:852867"
                     /db_xref="SGD:S000002985"
                     /translation="

MSDRFVIWAPSMHNEPAAKCGYCHGNKGGNMDQLFALDSWAHRYMNKMDVVKIENCTIGSFVEHMDVATYDRMCNMGFRRSGKFLYKVDPLRNCCRLYTIRTAPQELNMTKELKKCISRFATRITSEDYCPAAVASSDFVGKIVNAEMNSKTFYTRFEPALYSEEKYHLFVKYQEKVHQDYNNSPKSFKRFLCDTPFGPEAVLGTQESWEQLNNWQRMKPGEKLKHMGPVHECYYYEGKLIAITVSDILPSGISSVYFIWDPDYSKWSLGKLSALRDLAIIQRTNLQYYYLGYYIEDCPKMNYKANYGAEVLDVCHSKYIPLKPIQDMISRGKLFVIGEEETKVTKELYLVDSETGRGEGFPTDNVVKYKNIAEEIYGVGGCAFKSANESALELKELYGIPYEEEDLDTIYHLKEHNGHAPNGIPNVVPGLLPLWELLDIMQSGKITDLEGRLFLFEIETEGIRPLINFYSEPPNVKKRICDVIRLFGFETCMKAVILYSEQM"

     misc_feature    55..345
                     /gene="ATE1"
                     /locus_tag="YGL017W"
                     /note="Arginine-tRNA-protein transferase, N terminus;
                     Region: ATE_N; pfam04376"
                     /db_xref="CDD:461281"
     misc_feature    493..939
                     /gene="ATE1"
                     /locus_tag="YGL017W"
                     /note="Arginine-tRNA-protein transferase, C terminus;
                     Region: ATE_C; pfam04377"
                     /db_xref="CDD:461282"
ORIGIN      

atgtccgatagattcgttatttgggctccctcgatgcacaatgaacctgccgcaaagtgtgggtattgtcacggtaataaggggggcaacatggatcagttgttcgcattggattcgtgggctcatcgttatatgaacaaaatggacgttgtaaagattgaaaactgcacaattggctctttcgtggaacatatggatgtagccacgtatgatcgcatgtgtaatatgggatttagaaggtctggtaagtttctttataaagtggacccgttgaggaattgttgtaggttatacaccattcgaactgcccctcaagaattgaatatgacaaaggaattgaaaaaatgcatcagccgctttgctactagaataacaagtgaggactactgcccagccgctgttgcaagcagtgattttgtgggcaaaattgttaatgcagagatgaattctaaaacattctatacccgatttgagcctgcactttatagtgaagaaaagtatcacttatttgtcaaatatcaggaaaaagtgcatcaagactacaataattcgccgaagtcctttaagcgattcctatgtgatacgccctttggccctgaagcggtgttggggacacaagaatcatgggagcagttaaacaattggcagcgaatgaagccaggcgagaaactgaagcatatgggtcctgtgcacgaatgctactactatgagggtaaattaattgccatcactgtgtcagatatcttgcccagtggtatatcttcggtatattttatttgggatccagactacagtaaatggtccctagggaagctcagtgctttgcgcgatcttgccatcattcaaaggacaaatctgcaatactattacctggggtactatattgaggactgtccgaagatgaattataaagcaaactatggtgcggaagtactggatgtgtgtcacagtaaatatatcccattgaaacccattcaggatatgatttctaggggcaaactctttgtcataggtgaagaagagacgaaagttactaaggagctctacctcgttgactctgaaaccggaagaggggagggatttcccactgataatgttgtcaagtacaagaatattgctgaggaaatatacggtgtgggagggtgtgcgtttaaatctgcaaatgaatctgcattggaattgaaagaactttacggtataccgtacgaagaggaagatttagataccatctaccatttgaaagaacacaatggccatgctccaaatggtattcctaatgtggtgccgggattactcccgctatgggaattgctggacattatgcaatctggcaagatcactgacctggagggaagactatttctcttcgaaatcgaaacggaggggattcgaccattaattaacttttatagcgaacctccgaatgtcaagaaacgtatttgtgacgtgatacggttatttggcttcgaaacttgtatgaaagccgtcattttatatagtgagcaaatgtga

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