LOCUS       NM_001136547            1119 bp    mRNA    linear   VRT 12-JAN-2022
DEFINITION  Salmo salar PROP paired-like homeobox 1 (prop1), mRNA.
ACCESSION   NM_001136547
VERSION     NM_001136547.1
KEYWORDS    RefSeq.
SOURCE      Salmo salar (Atlantic salmon)
  ORGANISM  Salmo salar
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii;
            Salmoniformes; Salmonidae; Salmoninae; Salmo.
REFERENCE   1  (bases 1 to 1119)
  AUTHORS   Warren IA, Ciborowski KL, Casadei E, Hazlerigg DG, Martin S, Jordan
            WC and Sumner S.
  TITLE     Extensive local gene duplication and functional divergence among
            paralogs in Atlantic salmon
  JOURNAL   Genome Biol Evol 6 (7), 1790-1805 (2014)
   PUBMED   24951567
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1119)
  AUTHORS   Angotzi AR, Mungpakdee S, Stefansson S, Male R and Chourrout D.
  TITLE     Involvement of Prop1 homeobox gene in the early development of fish
            pituitary gland
  JOURNAL   Gen Comp Endocrinol 171 (3), 332-340 (2011)
   PUBMED   21362424
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from EF693961.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: EF693961.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN02864008, SAMN02864160
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..1119
                     /organism="Salmo salar"
                     /mol_type="mRNA"
                     /db_xref="taxon:8030"
                     /chromosome="ssa18"
                     /map="ssa18"
     gene            1..1119
                     /gene="prop1"
                     /note="PROP paired-like homeobox 1"
                     /db_xref="GeneID:100192335"
     exon            1..95
                     /gene="prop1"
                     /inference="alignment:Splign:2.1.0"
     CDS             2..718
                     /gene="prop1"
                     /note="Prop-1-like homeobox protein"
                     /codon_start=1
                     /product="PROP paired-like homeobox 1"
                     /protein_id="NP_001130019.1"
                     /db_xref="GeneID:100192335"
                     /translation="

MAQVKSPVDGVKSQQQRAEMYSDITIVSSSADVGSPARKGPFDSMALGLSRRGRAYPSPARRRHRTTFSHKQLDQLEMAFGQNHYPDIYCREELARLTKLNEARIQVWFQNRRAKYRRQERASQKLLPMAMMPGHGALLGSMCVQSTGLTRQYYPHSLAHHITRFPSMLPSGGCSHSHHPGSAGQCSCPTVPPEPQPPRQHEEWYSPLRNIGAPPSNLATPVFSLTSMPALDPGSHWN"

     misc_feature    <128..472
                     /gene="prop1"
                     /note="Homeodomain-containing transcription factor
                     [Transcription]; Region: COG5576"
                     /db_xref="CDD:227863"
     misc_feature    order(185..199,203..205,254..256,272..274,311..313,
                     317..322,329..334,338..346,350..355)
                     /gene="prop1"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:238039"
     misc_feature    191..352
                     /gene="prop1"
                     /note="Homeobox domain; Region: Homeobox; pfam00046"
                     /db_xref="CDD:425441"
     misc_feature    order(191..193,200..202,320..322,329..334,341..343)
                     /gene="prop1"
                     /note="specific DNA base contacts [nucleotide binding];
                     other site"
                     /db_xref="CDD:238039"
     exon            96..319
                     /gene="prop1"
                     /inference="alignment:Splign:2.1.0"
     exon            320..1095
                     /gene="prop1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      

gatggcccaggttaagtcacccgtggatggtgtcaagagtcagcagcagcgtgcagagatgtactctgatattaccatcgtcagctccagcgcagatgtgggcagcccagccagaaaaggcccatttgacagtatggctctagggctcagcaggcgtgggagagcctacccatccccagcacgcaggcgccatcgcaccaccttcagtcacaagcagctggaccagctggagatggcgtttggacagaaccactaccctgacatctactgccgtgaggaactagcgaggctcaccaaactcaatgaggcacgcatacaggtatggttccaaaatcgccgcgccaaataccgcaggcaggagcgtgcgtctcagaagctcttgccaatggccatgatgccagggcacggggcactgttgggcagcatgtgtgttcagtccacagggttgacccgtcagtactaccctcactccctggctcaccatatcacccggttcccctctatgctgccctcaggtggttgctcccactcccaccacccaggctcagccggccagtgttcctgccccacagtcccaccagagccacaacccccccgccagcacgaggagtggtacagcccgctacggaacattggagccccaccaagcaacctggccacacctgtgttctccctgacctccatgcctgctctagaccctggctctcactggaactaaagaaagagtaacttntacgtcaggaggtagacaagctcttttaggctgtgtctcaaagaactaacagttattcattgcaccttagattagattacaaaatacagttttttgtatctatgcagtgatagctagtaactaaagaacaggaagaatttagagaatagtgagaatgacttaactccttctcccattgaatacctgaaattgcatgtgttctgtgactagcagattaaagttcagggtagcctaactgagagaaagacatttgtgggtaattttgaattatccatatagattgtctgaaatatatactatacatctttctcctaacaatgccttttgtattttcactgtaaataaagttgtgtgtttcgggaaaaaaaaaaaaaaaaaaaaaaaaa

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