LOCUS       NM_001110530            1313 bp    mRNA    linear   VRT 21-DEC-2020
DEFINITION  Danio rerio claudin 8.3 (cldn8.3), mRNA.
ACCESSION   NM_001110530 XM_001341798
VERSION     NM_001110530.1
KEYWORDS    RefSeq.
SOURCE      Danio rerio (zebrafish)
  ORGANISM  Danio rerio
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Danionidae; Danioninae; Danio.
REFERENCE   1  (bases 1 to 1313)
  AUTHORS   Baltzegar DA, Reading BJ, Brune ES and Borski RJ.
  TITLE     Phylogenetic revision of the claudin gene family
  JOURNAL   Mar Genomics 11, 17-26 (2013)
   PUBMED   23726886
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC153385.1.
            
            On Nov 16, 2007 this sequence version replaced XM_001341798.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC153385.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA898400 [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..1313
                     /organism="Danio rerio"
                     /mol_type="mRNA"
                     /db_xref="taxon:7955"
                     /chromosome="15"
                     /map="15"
     gene            1..1313
                     /gene="cldn8.3"
                     /gene_synonym="cldn17; cldn8c; zgc:173444"
                     /note="claudin 8.3"
                     /db_xref="GeneID:100001934"
                     /db_xref="ZFIN:ZDB-GENE-070821-2"
     exon            1..60
                     /gene="cldn8.3"
                     /gene_synonym="cldn17; cldn8c; zgc:173444"
                     /inference="alignment:Splign:2.1.0"
     exon            61..140
                     /gene="cldn8.3"
                     /gene_synonym="cldn17; cldn8c; zgc:173444"
                     /inference="alignment:Splign:2.1.0"
     exon            141..211
                     /gene="cldn8.3"
                     /gene_synonym="cldn17; cldn8c; zgc:173444"
                     /inference="alignment:Splign:2.1.0"
     misc_feature    207..209
                     /gene="cldn8.3"
                     /gene_synonym="cldn17; cldn8c; zgc:173444"
                     /note="upstream in-frame stop codon"
     exon            212..1295
                     /gene="cldn8.3"
                     /gene_synonym="cldn17; cldn8c; zgc:173444"
                     /inference="alignment:Splign:2.1.0"
     CDS             234..1241
                     /gene="cldn8.3"
                     /gene_synonym="cldn17; cldn8c; zgc:173444"
                     /note="claudin 17"
                     /codon_start=1
                     /product="claudin-17"
                     /protein_id="NP_001104000.1"
                     /db_xref="GeneID:100001934"
                     /db_xref="ZFIN:ZDB-GENE-070821-2"
                     /translation="

MVQGPCDVIALCLSLIGLIGVATVTALPMWRVTAFIGENIIVMETRWEGLWMNCYRQANIRMQCKVYDSLLYLPPDLQAARGLTCCSLALCGFGIIVSLFGLRCMSCLSDQPRNKSIILMITGIIEILASFCIVIPVSWTAHTIIRDFYNPLLLDAQRRELGEALYIGWVTSAFLLASGVIFLCRRVDSNEQPFYARPPRNKQVPNHFQTFNSIRRQPLLQNNSFSTPQHSSAAFSFAVTPSSGQYSQHNVQPVVNGSLIYSPNMIPPQRVNYNGQNVMQSQILASNSQHPVSDPRDSFNTGSAFHPVQQNPLYVGYNYSRVQSGSSNSSTGLRI"

     misc_feature    270..779
                     /gene="cldn8.3"
                     /gene_synonym="cldn17; cldn8c; zgc:173444"
                     /note="PMP-22/EMP/MP20/Claudin family; Region:
                     PMP22_Claudin; cl21598"
                     /db_xref="CDD:451326"
ORIGIN      

ggtttgtcgtgtgaaactcaagtcacacatggtttcccagcggctcgacccgtcagacagatgtttgaaatcgaaagaagacaaactttacactttacacgtttgtactttacagcaatgtgatttggatcaaaatgaagatgtttgaaactgaaagaagaccaattctcagtttgtactttacagccatgtgatttggatcaaaatgagggatcacggatgagataataaaaatggttcagggtccgtgtgatgtcatcgccctctgcctgagcctcatcggtctgattggcgtcgccactgttacggctctcccgatgtggagagtcactgcattcataggagaaaacatcatcgtgatggagacccgctgggagggtttgtggatgaactgctacaggcaagccaacatccgaatgcagtgtaaagtgtacgactccctgctgtatcttcctcctgatctgcaggcggcccgcggattgacctgctgctctctggcgctgtgtggattcgggataatagtgtccctcttcggcctccgttgcatgtcttgtctgagtgatcaaccacgcaacaaaagcatcattttaatgatcactggcataattgaaattttagcaagtttttgcatcgtcatccctgtctcctggacggcccatactattatcagagacttttacaatccgttactattggatgcccagcggagagaactgggagaggctctgtatatcggttgggtaactagcgcgtttcttttggcatctggagtcatctttctctgtcgtcgtgttgattcgaacgagcagccattttatgctcgtccaccacgtaataaacaagttccgaatcatttccagacctttaactctatccgtcgtcagccgttgctccagaataatagtttttccactcctcagcattcatcagctgcattcagctttgctgtcacgccctctagtggtcaatattcacagcacaacgtgcagccggtggtcaatgggtctttaatatacagtccaaacatgattccacctcagagagtgaattataatgggcagaatgtaatgcaaagtcagattttagccagtaactcacagcaccctgtcagtgatcctcgggattcctttaacaccgggtctgcttttcatcctgtgcaacagaacccactgtatgtcgggtataattactcccgggtacagtctggtagctccaacagtagcacaggactgcggatataagagtttctctgtgttttaacttttatttaaaaataaagagtgctgaaaatgccaaaaaaaaaaaaaaaaaaa

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