LOCUS       NM_001017168            1216 bp    mRNA    linear   VRT 22-DEC-2019
DEFINITION  Xenopus tropicalis GS homeobox 2 (gsx2), mRNA.
ACCESSION   NM_001017168
VERSION     NM_001017168.2
KEYWORDS    RefSeq.
SOURCE      Xenopus tropicalis (tropical clawed frog)
  ORGANISM  Xenopus tropicalis
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae;
            Xenopus; Silurana.
REFERENCE   1  (bases 1 to 1216)
  AUTHORS   Illes JC, Winterbottom E and Isaacs HV.
  TITLE     Cloning and expression analysis of the anterior parahox genes, Gsh1
            and Gsh2 from Xenopus tropicalis
  JOURNAL   Dev. Dyn. 238 (1), 194-203 (2009)
   PUBMED   19097192
  REMARK    GeneRIF: Results show that Gsh1 and Gsh2 exhibit complex,
            overlapping patterns of expression within the anterior nervous
            system from open neural plate stages.
REFERENCE   2  (bases 1 to 1216)
  AUTHORS   Klein SL, Strausberg RL, Wagner L, Pontius J, Clifton SW and
            Richardson P.
  TITLE     Genetic and genomic tools for Xenopus research: The NIH Xenopus
            initiative
  JOURNAL   Dev. Dyn. 225 (4), 384-391 (2002)
   PUBMED   12454917
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CR855836.2.
            
            On Oct 14, 2005 this sequence version replaced NM_001017168.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: CR855836.2 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00028291, SAMD00028292
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..1216
                     /organism="Xenopus tropicalis"
                     /mol_type="mRNA"
                     /db_xref="taxon:8364"
                     /chromosome="1"
                     /map="1"
     gene            1..1216
                     /gene="gsx2"
                     /gene_synonym="gsh2"
                     /note="GS homeobox 2"
                     /db_xref="GeneID:549922"
                     /db_xref="Xenbase:XB-GENE-492505"
     misc_feature    37..39
                     /gene="gsx2"
                     /gene_synonym="gsh2"
                     /note="upstream in-frame stop codon"
     CDS             49..795
                     /gene="gsx2"
                     /gene_synonym="gsh2"
                     /note="genomic screened homeo box 2; genomic-screened
                     homeobox 2"
                     /codon_start=1
                     /product="GS homeobox 2"
                     /protein_id="NP_001017168.1"
                     /db_xref="GeneID:549922"
                     /db_xref="Xenbase:XB-GENE-492505"
                     /translation="

MSRSFYVDSLIIKDSSSRPIPALPDLSHHHHHHHGQDFLLPISMPSPTVMSVHAPVCPSRKSGSFCVCPICVASHLHSSRNSIPLLKGHFPNGEAQYCQRVSQQPSPAMVHPAHSPVCSPTYNVTDPRRFHCMTMGGAENSQAQNGKRMRTAFSSTQLLELEREFSSNMYLSRLRRIEIATYLSLSEKQVKIWFQNRRVKHKKENKGSQRNTHGGCKCTGPQGHYPRSEDEDSLSTASTSEDKEVSPL"

     misc_feature    order(487..501,505..507,556..558,574..576,613..615,
                     619..624,631..636,640..648,652..657)
                     /gene="gsx2"
                     /gene_synonym="gsh2"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:238039"
     misc_feature    order(493..495,502..504,622..624,631..636,643..645)
                     /gene="gsx2"
                     /gene_synonym="gsh2"
                     /note="specific DNA base contacts [nucleotide binding];
                     other site"
                     /db_xref="CDD:238039"
     misc_feature    496..654
                     /gene="gsx2"
                     /gene_synonym="gsh2"
                     /note="Homeobox domain; Region: Homeobox; pfam00046"
                     /db_xref="CDD:425441"
     regulatory      1140..1145
                     /regulatory_class="polyA_signal_sequence"
                     /gene="gsx2"
                     /gene_synonym="gsh2"
     polyA_site      1158
                     /gene="gsx2"
                     /gene_synonym="gsh2"
ORIGIN      

ctgtcactgagagaggagaaggagctgtctgactgctgagctgcggcaatgtctaggtctttttatgttgactctctaattatcaaagattcctcctcaagaccaattccagccttgcctgatctctcccaccaccatcatcatcatcatgggcaggatttccttctgcctatcagcatgccatctccaacagtcatgtcggtgcatgcccctgtgtgcccttctaggaaaagtggcagcttttgtgtgtgtcccatctgtgtggcatctcacctgcactccagccggaatagcatccctctgctcaagggccacttccctaatggggaggcgcagtactgccagagggtgagccaacagcccagcccagccatggtccacccagcgcattcacctgtctgcagcccaacctacaacgttacggaccccaggagattccattgcatgacaatgggtggagcagagaacagccaagcgcagaatggcaagcgaatgaggactgcatttagcagcacccagcttctggagctggagagagaattctcctccaacatgtacctgtccaggctgaggaggatcgagattgccacctacctgagcctgtcagagaagcaggtgaagatctggtttcagaacaggagggtaaagcacaagaaagagaataagggctcccaaaggaacacccatgggggctgcaagtgcacagggccacaaggccattacccccgatcagaagacgaagattccttgtctacagcttcaacaagtgaggataaggaggtgtcacctttataaattgctctacctgcatacatgtctctgtgactctatggcacttatgatctacaccaggaaaactatattgactcatccaaatgcccctttattccacaatcagctcagttaaagcctttggacaaatctcagtttctgttgattttggggattgaatatatgtgtccctaggatgggaaaatgtcatgggttcgttttataaagaatgtgtttttgttacagtcagaaaattagtcggatgtaggtttttatgcaaaggtctgtaaatagtctcatgccctaacgttttgcaaatccacctgcgagtgaatagttttatacaaatttatatttatatttatttaaataaacgaagatatgggtaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaa

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