LOCUS       NM_001005459            1377 bp    mRNA    linear   VRT 20-JUN-2021
DEFINITION  Xenopus tropicalis empty spiracles homeobox 1 (emx1), mRNA.
ACCESSION   NM_001005459
VERSION     NM_001005459.1
KEYWORDS    RefSeq.
SOURCE      Xenopus tropicalis (tropical clawed frog)
  ORGANISM  Xenopus tropicalis
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae;
            Xenopus; Silurana.
REFERENCE   1  (bases 1 to 1377)
  AUTHORS   Klein SL, Strausberg RL, Wagner L, Pontius J, Clifton SW and
            Richardson P.
  TITLE     Genetic and genomic tools for Xenopus research: The NIH Xenopus
            initiative
  JOURNAL   Dev Dyn 225 (4), 384-391 (2002)
   PUBMED   12454917
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC074580.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC074580.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00028292, SAMD00028293
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..1377
                     /organism="Xenopus tropicalis"
                     /mol_type="mRNA"
                     /db_xref="taxon:8364"
                     /chromosome="1"
                     /map="1"
     gene            1..1377
                     /gene="emx1"
                     /note="empty spiracles homeobox 1"
                     /db_xref="GeneID:448058"
                     /db_xref="Xenbase:XB-GENE-920144"
     exon            1..558
                     /gene="emx1"
                     /inference="alignment:Splign:2.1.0"
     misc_feature    129..131
                     /gene="emx1"
                     /note="upstream in-frame stop codon"
     CDS             210..911
                     /gene="emx1"
                     /note="empty spiracles homeobox 1, gene 2; empty spiracles
                     homolog 1; empty spiracles-like protein 1"
                     /codon_start=1
                     /product="homeobox protein EMX1"
                     /protein_id="NP_001005459.1"
                     /db_xref="GeneID:448058"
                     /db_xref="Xenbase:XB-GENE-920144"
                     /translation="

MFQPAGKRCFTIESLVAKDNPLSSEEPLRPAALPYPGAPAEAFVSGFPSPAGRSLYNNPELVFPETVSHPPLTVHPHQLGASHLQHPHSFFAPQHRDPLNFYPWVLRNRFFGHRFQGGDVSQESLLLHGPFARKPKRIRTAFSPSQLLRLERAFEKNHYVVGAERKQLASSLSLSETQVKVWFQNRRTKYKRQKLEEEGPDSDQKKKGSHHINRWRLATKQPNGEDIDVTSND"

     misc_feature    462..>791
                     /gene="emx1"
                     /note="Homeodomain-containing transcription factor
                     [Transcription]; Region: COG5576"
                     /db_xref="CDD:227863"
     misc_feature    order(615..629,633..635,684..686,702..704,741..743,
                     747..752,759..764,768..776,780..785)
                     /gene="emx1"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:238039"
     misc_feature    order(621..623,630..632,750..752,759..764,771..773)
                     /gene="emx1"
                     /note="specific DNA base contacts [nucleotide binding];
                     other site"
                     /db_xref="CDD:238039"
     misc_feature    624..782
                     /gene="emx1"
                     /note="Homeobox domain; Region: Homeobox; pfam00046"
                     /db_xref="CDD:425441"
     misc_feature    783..908
                     /gene="emx1"
                     /note="propagated from UniProtKB/Swiss-Prot (Q6GLB9.1);
                     Region: Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite"
     exon            559..743
                     /gene="emx1"
                     /inference="alignment:Splign:2.1.0"
     exon            744..1338
                     /gene="emx1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      

gagcggcaggtaacagcgagtggagcagtggagctctctcctctctctcctctctctctctctctttctggccaaggtggatggagttgggagccttctctggacactgagctgagtcctttccccagtagctggatacttctgttgggggctggggggctgcaattggctgtgagctcggtgggacacggttcggcccctcaggcaccatgttccagcctgcaggaaagcgctgcttcaccatcgaatcgctggtggcaaaggacaatcccctgagctccgaggagcccctgagaccggcggccctcccctaccctggggccccagcagaagcctttgtcagcggattccccagcccagccggacggtccctctataacaacccggagcttgtgttccctgagactgtcagccacccacccctgactgtgcacccccaccagctgggggcatctcacctacagcacccacactcattcttcgcaccccagcacagggaccctctcaacttctacccctgggtgctcaggaacaggttctttgggcacagatttcaaggcggcgacgtttcccaggagagtttgctcctacacggcccattcgccaggaaacccaaacggatcagaacggccttctccccgtctcagctgctcaggctggagagggcatttgagaagaaccattatgtggtgggggctgaacggaaacagttggccagcagcctcagtctgtctgagacccaggtgaaggtttggttccagaacagaaggacaaaatacaaaaggcagaagttggaagaggaaggtccagattctgatcagaagaaaaaaggttctcatcacatcaaccggtggcgattggccaccaaacagcccaatggggaagacattgatgttacctccaatgactagtagggtcacgtgtgcgagtcaatgtagggatcagactggaaacaaactcccaaggaactcactgataccgaatcggaacagtcttgctcagacgccaaggaggactattagagacctgctaacacctaggcccaagggcagcaggattaacccgcaggaggagcaacacgcgcacttgttctatgaaggacggaggtggactggtccacccaatggctgatctctctcatgaacttttgtcagccacaagccgtctatcagcaactggtcgaaacaaaatgtctcacctgtcctctgtctttttttcggcttttttttttccctttttgctaatttttaatttattttcttttcctaatataaaaaagtagctattaccaatttagtgcttaaatgtgtgttaataaatatcatatggatacatcaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaa

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