{"error":"none","results":[{"aa_position":[],"accession":"NM_001171092","definition":"Homo sapiens claudin 2 (CLDN2), transcript variant 2, mRNA.","division":"RefSeq","geneid":"9075","gi":"","length":"3163","nt_position":[],"snippet":"Hominidae; Homo. REFERENCE COMMENT REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AF177340.1, AK075405.1 and AA973123.1. Summary: This gene product belongs to the claudin protein family whose members have been identified as major integral membrane proteins localized exclusively at tight junctions. Claudins are expressed in an organ-specific manner and regulate tissue-specific physiologic properties of tight junctions. This protein is expressed in the intestine. Alternatively spliced transcript variants with different 5' untranslated region...","source":"Homo sapiens (human)","symbol":"CLDN2","synonym":"claudin-2; OAZON","version":"NM_001171092.1"},{"aa_position":[],"accession":"NM_001171095","definition":"Homo sapiens claudin 2 (CLDN2), transcript variant 3, mRNA.","division":"RefSeq","geneid":"9075","gi":"","length":"2921","nt_position":[],"snippet":"This record has been curated by NCBI staff. The reference sequence was derived from AK312515.1, AK075405.1 and AA973123.1. On Aug 13, 2020 this sequence version replaced NM_001171095.1. Summary: This gene product belongs to the claudin protein family whose members have been identified as major integral membrane proteins localized exclusively at tight junctions. Claudins are expressed in an organ-specific manner and regulate tissue-specific physiologic properties of tight junctions. This protein is expressed in the intestine. Alternatively spliced transcript variants with different 5'...","source":"Homo sapiens (human)","symbol":"CLDN2","synonym":"claudin-2; OAZON","version":"NM_001171095.2"},{"aa_position":[],"accession":"NM_020384","definition":"Homo sapiens claudin 2 (CLDN2), transcript variant 1, mRNA.","division":"RefSeq","geneid":"9075","gi":"","length":"2961","nt_position":[],"snippet":"was derived from DA743944.1, AK075405.1 and AA973123.1. This sequence is a reference standard in the RefSeqGene project. On Jun 2, 2019 this sequence version replaced NM_020384.3. Summary: This gene product belongs to the claudin protein family whose members have been identified as major integral membrane proteins localized exclusively at tight junctions. Claudins are expressed in an organ-specific manner and regulate tissue-specific physiologic properties of tight junctions. This protein is expressed in the intestine. Alternatively spliced transcript variants with different 5' untranslated...","source":"Homo sapiens (human)","symbol":"CLDN2","synonym":"claudin-2; OAZON","version":"NM_020384.4"},{"aa_position":[],"accession":"XM_054328084","definition":"PREDICTED: Homo sapiens claudin 2 (CLDN2), transcript variant X1, mRNA.","division":"RefSeq","geneid":"9075","gi":"","length":"2904","nt_position":[],"snippet":"CDS 272..964 /gene=\"CLDN2\" /gene_synonym=\"claudin-2; OAZON\" /codon_start=1 /product=\"claudin-2 isoform X1\" /protein_id=\"XP_054184059.1\" /db_xref=\"GeneID:9075\" /db_xref=\"HGNC:HGNC:2041\" /db_xref=\"MIM:300520\" /translation=\"MASLGLQLVGYILGLLGLLGTLVAMLLPSWKTSSYVGASIVTAVGFSKGLWMECATHSTGITQCDIYSTLLGLPADIQAAQAMMVTSSAISSLACIISVVGMRCTVFCQESRAKDRVAVAGGVFFILGGLLGFIPVAWNLHGILRDFYSPLVPDSMKFEIGEALYLGIISSLFSLIAGIILCFSCSSQRNRSNYYDAYQAQPLATRSSPRPGQPPKVKSEFNSYSLTGYV\" misc_feature 338..814 /gene=\"CLDN2\" /gene_synonym=\"claudin-2; OAZON\" /note=\"PMP-22/EMP/MP20/Claudin family; Region: PMP22_Claudin; cl21598\" /db_...","source":"Homo sapiens (human)","symbol":"CLDN2","synonym":"claudin-2; OAZON","version":"XM_054328084.1"},{"aa_position":[],"accession":"XM_054328085","definition":"PREDICTED: Homo sapiens claudin 2 (CLDN2), transcript variant X2, mRNA.","division":"RefSeq","geneid":"9075","gi":"","length":"3124","nt_position":[],"snippet":"CDS 492..1184 /gene=\"CLDN2\" /gene_synonym=\"claudin-2; OAZON\" /codon_start=1 /product=\"claudin-2 isoform X1\" /protein_id=\"XP_054184060.1\" /db_xref=\"GeneID:9075\" /db_xref=\"HGNC:HGNC:2041\" /db_xref=\"MIM:300520\" /translation=\"MASLGLQLVGYILGLLGLLGTLVAMLLPSWKTSSYVGASIVTAVGFSKGLWMECATHSTGITQCDIYSTLLGLPADIQAAQAMMVTSSAISSLACIISVVGMRCTVFCQESRAKDRVAVAGGVFFILGGLLGFIPVAWNLHGILRDFYSPLVPDSMKFEIGEALYLGIISSLFSLIAGIILCFSCSSQRNRSNYYDAYQAQPLATRSSPRPGQPPKVKSEFNSYSLTGYV\" misc_feature 558..1034 /gene=\"CLDN2\" /gene_synonym=\"claudin-2; OAZON\" /note=\"PMP-22/EMP/MP20/Claudin family; Region: PMP22_Claudin; cl21598\" /db_...","source":"Homo sapiens (human)","symbol":"CLDN2","synonym":"claudin-2; OAZON","version":"XM_054328085.1"},{"aa_position":[],"accession":"NM_001185023","definition":"Homo sapiens claudin 7 (CLDN7), transcript variant 3, mRNA.","division":"RefSeq","geneid":"1366","gi":"","length":"1457","nt_position":[],"snippet":"Hominidae; Homo. REFERENCE COMMENT REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from CV575841.1, AC003688.1 and BC071844.1. On Aug 14, 2020 this sequence version replaced NM_001185023.1. Summary: This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining...","source":"Homo sapiens (human)","symbol":"CLDN7","synonym":"CEPTRL2; claudin-1; CLDN-7; CPETRL2; Hs.84359","version":"NM_001185023.2"},{"aa_position":[],"accession":"NM_001185022","definition":"Homo sapiens claudin 7 (CLDN7), transcript variant 2, mRNA.","division":"RefSeq","geneid":"1366","gi":"","length":"1462","nt_position":[],"snippet":"Hominidae; Homo. REFERENCE COMMENT REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC003688.1, AJ011497.1 and BC071844.1. On Aug 14, 2020 this sequence version replaced NM_001185022.1. Summary: This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining...","source":"Homo sapiens (human)","symbol":"CLDN7","synonym":"CEPTRL2; claudin-1; CLDN-7; CPETRL2; Hs.84359","version":"NM_001185022.2"},{"aa_position":[],"accession":"NM_001307","definition":"Homo sapiens claudin 7 (CLDN7), transcript variant 1, mRNA.","division":"RefSeq","geneid":"1366","gi":"","length":"1542","nt_position":[],"snippet":"Hominidae; Homo. REFERENCE COMMENT REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from CV575841.1, AC003688.1 and BC071844.1. On Nov 23, 2018 this sequence version replaced NM_001307.5. Summary: This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining...","source":"Homo sapiens (human)","symbol":"CLDN7","synonym":"CEPTRL2; claudin-1; CLDN-7; CPETRL2; Hs.84359","version":"NM_001307.6"},{"aa_position":[],"accession":"XM_054319737","definition":"PREDICTED: Homo sapiens claudin domain containing 2 (CLDND2), transcript variant X9, mRNA.","division":"RefSeq","geneid":"125875","gi":"","length":"839","nt_position":[],"snippet":"db_xref=\"GeneID:125875\" /db_xref=\"HGNC:HGNC:28511\" CDS 292..795 /gene=\"CLDND2\" /codon_start=1 /product=\"claudin domain-containing protein 2 isoform X2\" /protein_id=\"XP_054175712.1\" /db_xref=\"GeneID:125875\" /db_xref=\"HGNC:HGNC:28511\" /translation=\"MGVKRSLQSGGILLSLVANVLMVLSTATNYWTRQQEGHSGLWQECNHGICSSIPCQTTLAVTVACMVLAVGVGVVGMVMGLRIRCDEGESLRGQTTSAFLFLGGLLLLTALIGYTVKNAWKNNVFFSWSYFSGWLALPFSILAGFCFLLADMIMQSTDAISGFPVCL\" misc_feature 319..723 /gene=\"CLDND2\" /note=\"PMP-22/EMP/MP20/Claudin family; Region: PMP22_Claudin; cl21598\" /db_xref=\"CDD:473919\" ORIGIN //...","source":"Homo sapiens (human)","symbol":"CLDND2","synonym":"","version":"XM_054319737.1"},{"aa_position":[],"accession":"XM_054319736","definition":"PREDICTED: Homo sapiens claudin domain containing 2 (CLDND2), transcript variant X8, mRNA.","division":"RefSeq","geneid":"125875","gi":"","length":"852","nt_position":[],"snippet":"db_xref=\"GeneID:125875\" /db_xref=\"HGNC:HGNC:28511\" CDS 305..808 /gene=\"CLDND2\" /codon_start=1 /product=\"claudin domain-containing protein 2 isoform X2\" /protein_id=\"XP_054175711.1\" /db_xref=\"GeneID:125875\" /db_xref=\"HGNC:HGNC:28511\" /translation=\"MGVKRSLQSGGILLSLVANVLMVLSTATNYWTRQQEGHSGLWQECNHGICSSIPCQTTLAVTVACMVLAVGVGVVGMVMGLRIRCDEGESLRGQTTSAFLFLGGLLLLTALIGYTVKNAWKNNVFFSWSYFSGWLALPFSILAGFCFLLADMIMQSTDAISGFPVCL\" misc_feature 332..736 /gene=\"CLDND2\" /note=\"PMP-22/EMP/MP20/Claudin family; Region: PMP22_Claudin; cl21598\" /db_xref=\"CDD:473919\" ORIGIN //...","source":"Homo sapiens (human)","symbol":"CLDND2","synonym":"","version":"XM_054319736.1"},{"aa_position":[],"accession":"XM_054375166","definition":"PREDICTED: Homo sapiens claudin 10 (CLDN10), transcript variant X1, mRNA.","division":"RefSeq","geneid":"9071","gi":"","length":"3898","nt_position":[],"snippet":"gene=\"CLDN10\" /gene_synonym=\"CPETRL3; HELIX; OSP-L; OSPL\" /codon_start=1 /product=\"claudin-10 isoform X1\" /protein_id=\"XP_054231141.1\" /db_xref=\"GeneID:9071\" /db_xref=\"HGNC:HGNC:2033\" /db_xref=\"MIM:617579\" /translation=\"MRKINKLWLLFMLEKGYIQACRGLMIAAVSLGFFGSIFALFGMKCTKVGGSDKAKAKIACLAGIVFILSGLCSMTGCSLYANKITTEFFDPLFVEQKYELGAALFIGWAGASLCIIGGVIFCFSISDNNKTPRYTYNGATSVMSSRTKYHGGEDFKTTNPSKQFDKNAYV\" misc_feature <1686..2003 /gene=\"CLDN10\" /gene_synonym=\"CPETRL3; HELIX; OSP-L; OSPL\" /note=\"PMP-22/EMP/MP20/Claudin family; Region: PMP22_Claudin; cl21598\" /db_xref=\"CDD:473919\" ORIGIN //...","source":"Homo sapiens (human)","symbol":"CLDN10","synonym":"CPETRL3; HELIX; OSP-L; OSPL","version":"XM_054375166.1"},{"aa_position":[],"accession":"XM_054319735","definition":"PREDICTED: Homo sapiens claudin domain containing 2 (CLDND2), transcript variant X7, mRNA.","division":"RefSeq","geneid":"125875","gi":"","length":"1439","nt_position":[],"snippet":"gene=\"CLDND2\" /codon_start=1 /product=\"claudin domain-containing protein 2 isoform X1\" /protein_id=\"XP_054175710.1\" /db_xref=\"GeneID:125875\" /db_xref=\"HGNC:HGNC:28511\" /translation=\"MGVKRSLQSGGILLSLVANVLMVLSTATNYWTRQQEGHSGLWQECNHGICSSIPCQTTLAVTVACMVLAVGVGVVGMVMGLRIRCDEGESLRGQTTSAFLFLGGLLLLTALIGYTVKNAWKNNVFFSWSYFSGWLALPFSILAGKLDSGKRVEETAQKTLTPEAPQLPSQETPGTSRGLPNTLTTPADPAETPLEPQTPVPGALPAIRPRAHLPLPAPHPRPPRLLLSAGRHDHAEHRRHQWIPRVSVTAACLGQNKGTAFFSAAAPRAFLRVVGTQARGCIEAQGRHKDMNS\" misc_feature 319..729 /gene=\"CLDND2\" /note=\"PMP-22/EMP/MP20/Claudin family; Region: PMP22_Claudin; cl21598\" /db_xref=\"CDD...","source":"Homo sapiens (human)","symbol":"CLDND2","synonym":"","version":"XM_054319735.1"},{"aa_position":[],"accession":"XM_054319734","definition":"PREDICTED: Homo sapiens claudin domain containing 2 (CLDND2), transcript variant X6, mRNA.","division":"RefSeq","geneid":"125875","gi":"","length":"1452","nt_position":[],"snippet":"gene=\"CLDND2\" /codon_start=1 /product=\"claudin domain-containing protein 2 isoform X1\" /protein_id=\"XP_054175709.1\" /db_xref=\"GeneID:125875\" /db_xref=\"HGNC:HGNC:28511\" /translation=\"MGVKRSLQSGGILLSLVANVLMVLSTATNYWTRQQEGHSGLWQECNHGICSSIPCQTTLAVTVACMVLAVGVGVVGMVMGLRIRCDEGESLRGQTTSAFLFLGGLLLLTALIGYTVKNAWKNNVFFSWSYFSGWLALPFSILAGKLDSGKRVEETAQKTLTPEAPQLPSQETPGTSRGLPNTLTTPADPAETPLEPQTPVPGALPAIRPRAHLPLPAPHPRPPRLLLSAGRHDHAEHRRHQWIPRVSVTAACLGQNKGTAFFSAAAPRAFLRVVGTQARGCIEAQGRHKDMNS\" misc_feature 332..742 /gene=\"CLDND2\" /note=\"PMP-22/EMP/MP20/Claudin family; Region: PMP22_Claudin; cl21598\" /db_xref=\"CDD...","source":"Homo sapiens (human)","symbol":"CLDND2","synonym":"","version":"XM_054319734.1"},{"aa_position":[],"accession":"XM_054344990","definition":"PREDICTED: Homo sapiens claudin 16 (CLDN16), transcript variant X1, mRNA.","division":"RefSeq","geneid":"10686","gi":"","length":"3083","nt_position":[],"snippet":"CLDN16\" /gene_synonym=\"HOMG3; PCLN1\" /codon_start=1 /product=\"claudin-16 isoform X1\" /protein_id=\"XP_054200965.1\" /db_xref=\"GeneID:10686\" /db_xref=\"HGNC:HGNC:2037\" /db_xref=\"MIM:603959\" /translation=\"MRDLLQYIACFFAFFSAGFLIVATWTDCWMVNADDSLEVSTKCRGLWWECVTNAFDGIRTCDEYDSILAEHPLKLVVTRALMITADILAGFGFLTLLLGLDCVKFLPDEPYIKVRICFVAGATLLIAGTPGIIGSVWYAVDVYVERSTLVLHNIFLGIQYKFGWSCWLGMAGSLGCFLAGAVLTCCLYLFKDVGPERNYPYSLRKAYSAAGVSMAKSYSAPRTETAKMYAVDTRV\" misc_feature 304..822 /gene=\"CLDN16\" /gene_synonym=\"HOMG3; PCLN1\" /note=\"PMP-22/EMP/MP20/Claudin family; Region: PMP22_Claudin; cl21598\" /db_xref=\"CDD:473919\"...","source":"Homo sapiens (human)","symbol":"CLDN16","synonym":"HOMG3; PCLN1","version":"XM_054344990.1"},{"aa_position":[],"accession":"XM_054324413","definition":"PREDICTED: Homo sapiens claudin 14 (CLDN14), transcript variant X2, mRNA.","division":"RefSeq","geneid":"23562","gi":"","length":"2277","nt_position":[],"snippet":"gene=\"CLDN14\" /gene_synonym=\"DFNB29\" /codon_start=1 /product=\"claudin-14 isoform X1\" /protein_id=\"XP_054180388.1\" /db_xref=\"GeneID:23562\" /db_xref=\"HGNC:HGNC:2035\" /db_xref=\"MIM:605608\" /translation=\"MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTGIYQCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKGTPAKTTFAILGGTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGTLLCLSCQDEAPYRPYQAPPRATTTTANTAPAYQPPAAYKDNRAPSVTSATHSGYRLNDYV\" misc_feature 1269..1745 /gene=\"CLDN14\" /gene_synonym=\"DFNB29\" /note=\"PMP-22/EMP/MP20/Claudin family; Region: PMP22_Claudin; cl21598\" /db_xref=\"CDD:473919\"...","source":"Homo sapiens (human)","symbol":"CLDN14","synonym":"DFNB29","version":"XM_054324413.1"},{"aa_position":[],"accession":"XM_054319738","definition":"PREDICTED: Homo sapiens claudin domain containing 2 (CLDND2), transcript variant X5, mRNA.","division":"RefSeq","geneid":"125875","gi":"","length":"1262","nt_position":[],"snippet":"LOCUS XM_054319738 1262 bp mRNA linear PRI 05-AUG-2025 DEFINITION PREDICTED: Homo sapiens claudin domain containing 2 (CLDND2), transcript variant X5, mRNA. ACCESSION XM_054319738 VERSION XM_054319738.1 DBLINK BioProject: PRJNA807723 KEYWORDS RefSeq. SOURCE Homo sapiens (human) ORGANISM Homo sapiens Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. COMMENT MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_060943)...","source":"Homo sapiens (human)","symbol":"CLDND2","synonym":"","version":"XM_054319738.1"},{"aa_position":[],"accession":"NM_001426402","definition":"Homo sapiens claudin 5 (CLDN5), transcript variant 5, mRNA.","division":"RefSeq","geneid":"7122","gi":"","length":"1699","nt_position":[],"snippet":"PRI 01-MAY-2025 DEFINITION Homo sapiens claudin 5 (CLDN5), transcript variant 5, mRNA. ACCESSION NM_001426402 VERSION NM_001426402.1 KEYWORDS RefSeq. SOURCE Homo sapiens (human) ORGANISM Homo sapiens Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. REFERENCE COMMENT REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from CP068256.2. Summary: This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components...","source":"Homo sapiens (human)","symbol":"CLDN5","synonym":"AWAL; BEC1; CPETRL1; TMDVCF; TMVCF","version":"NM_001426402.1"},{"aa_position":[],"accession":"XM_054340597","definition":"PREDICTED: Homo sapiens transmembrane protein 182 (TMEM182), transcript variant X5, mRNA.","division":"RefSeq","geneid":"130827","gi":"","length":"2010","nt_position":[],"snippet":"protein 182 isoform X4\" /protein_id=\"XP_054196572.1\" /db_xref=\"GeneID:130827\" /db_xref=\"HGNC:HGNC:26391\" /translation=\"MRLNIAIFFGALFGALGVLLFLVAFGSDYWLLATEVGRCSGEKNIENVTFHHEGFFWRCWFNGIVEENDSNIWKFWYTNQPPSKNCTHAYLSPYPFMRGEHNSTSYDSAVSLL\" misc_feature 230..>523 /gene=\"TMEM182\" /note=\"PMP-22/EMP/MP20/Claudin family; Region: PMP22_Claudin; cl21598\" /db_xref=\"CDD:473919\" polyA_site 2010 /gene=\"TMEM182\" /experiment=\"COORDINATES: polyA evidence [ECO:0006239]\" ORIGIN //...","source":"Homo sapiens (human)","symbol":"TMEM182","synonym":"","version":"XM_054340597.1"},{"aa_position":[],"accession":"XM_054340596","definition":"PREDICTED: Homo sapiens transmembrane protein 182 (TMEM182), transcript variant X4, mRNA.","division":"RefSeq","geneid":"130827","gi":"","length":"843","nt_position":[],"snippet":"protein 182 isoform X3\" /protein_id=\"XP_054196571.1\" /db_xref=\"GeneID:130827\" /db_xref=\"HGNC:HGNC:26391\" /translation=\"MRGEHNSTSYDSAVIYRGFWAVLMLLGVVAVVIASFLIICAAPFASHFLYKAGGGSYIAADGISSLCYSSLSKSLLSQPLRETSSAINDISLLQALMPLLGWTSHWTCITVGLY\" misc_feature 415 /gene=\"TMEM182\" /note=\"PMP-22/EMP/MP20/Claudin family; Region: PMP22_Claudin; cl21598\" /db_xref=\"CDD:473919\" polyA_site 843 /gene=\"TMEM182\" /experiment=\"COORDINATES: polyA evidence [ECO:0006239]\" ORIGIN //...","source":"Homo sapiens (human)","symbol":"TMEM182","synonym":"","version":"XM_054340596.1"},{"aa_position":[],"accession":"XM_054340595","definition":"PREDICTED: Homo sapiens transmembrane protein 182 (TMEM182), transcript variant X2, mRNA.","division":"RefSeq","geneid":"130827","gi":"","length":"3450","nt_position":[],"snippet":"db_xref=\"HGNC:HGNC:26391\" /translation=\"MRLNIAIFFGALFGALGVLLFLVAFGSDYWLLATEVGRCSGEKNIENVTFHHEGFFWRCWFNGIVEENDSNIWKFWYTNQPPSKNCTHAYLSPYPFMRGEHNSTSYDSAVSILFSLVVMLYVIWVQAVADMESYRNMKMKDCLDFTPSVLYGWSFFLAPAGIFFSLLAGLLFLVVGRHIQIHH\" misc_feature 230..709 /gene=\"TMEM182\" /note=\"PMP-22/EMP/MP20/Claudin family; Region: PMP22_Claudin; cl21598\" /db_xref=\"CDD:473919\" ORIGIN //...","source":"Homo sapiens (human)","symbol":"TMEM182","synonym":"","version":"XM_054340595.1"},{"aa_position":[],"accession":"XM_054340584","definition":"PREDICTED: Homo sapiens transmembrane protein 178A (TMEM178A), transcript variant X9, mRNA.","division":"RefSeq","geneid":"130733","gi":"","length":"1560","nt_position":[],"snippet":"id=\"XP_054196559.1\" /db_xref=\"GeneID:130733\" /db_xref=\"HGNC:HGNC:28517\" /translation=\"MAVAVLLCGCIVATVSFFWEESLTQHVAGLLFLMTGIFCTISLCTYAASISYDLNRLPKLIYSLPADVEHGYSWSIFCAWCSLGFIVAAGGLCIAYPFISRTKIAQLKSGRDSTV\" misc_feature <504..776 /gene=\"TMEM178A\" /gene_synonym=\"TMEM178\" /note=\"PMP-22/EMP/MP20/Claudin family; Region: PMP22_Claudin; cl21598\" /db_xref=\"CDD:473919\" ORIGIN //...","source":"Homo sapiens (human)","symbol":"TMEM178A","synonym":"TMEM178","version":"XM_054340584.1"},{"aa_position":[],"accession":"XM_054340582","definition":"PREDICTED: Homo sapiens transmembrane protein 178A (TMEM178A), transcript variant X7, mRNA.","division":"RefSeq","geneid":"130733","gi":"","length":"1621","nt_position":[],"snippet":"id=\"XP_054196557.1\" /db_xref=\"GeneID:130733\" /db_xref=\"HGNC:HGNC:28517\" /translation=\"MAVAVLLCGCIVATVSFFWEESLTQHVAGLLFLMTGIFCTISLCTYAASISYDLNRLPKLIYSLPADVEHGYSWSIFCAWCSLGFIVAAGGLCIAYPFISRTKIAQLKSGRDSTV\" misc_feature <565..837 /gene=\"TMEM178A\" /gene_synonym=\"TMEM178\" /note=\"PMP-22/EMP/MP20/Claudin family; Region: PMP22_Claudin; cl21598\" /db_xref=\"CDD:473919\" ORIGIN //...","source":"Homo sapiens (human)","symbol":"TMEM178A","synonym":"TMEM178","version":"XM_054340582.1"},{"aa_position":[],"accession":"XM_054340585","definition":"PREDICTED: Homo sapiens transmembrane protein 178A (TMEM178A), transcript variant X10, mRNA.","division":"RefSeq","geneid":"130733","gi":"","length":"1558","nt_position":[],"snippet":"id=\"XP_054196560.1\" /db_xref=\"GeneID:130733\" /db_xref=\"HGNC:HGNC:28517\" /translation=\"MAVAVLLCGCIVATVSFFWEESLTQHVAGLLFLMTGIFCTISLCTYAASISYDLNRLPKLIYSLPADVEHGYSWSIFCAWCSLGFIVAAGGLCIAYPFISRTKIAQLKSGRDSTV\" misc_feature <502..774 /gene=\"TMEM178A\" /gene_synonym=\"TMEM178\" /note=\"PMP-22/EMP/MP20/Claudin family; Region: PMP22_Claudin; cl21598\" /db_xref=\"CDD:473919\" ORIGIN //...","source":"Homo sapiens (human)","symbol":"TMEM178A","synonym":"TMEM178","version":"XM_054340585.1"},{"aa_position":[],"accession":"XM_054340583","definition":"PREDICTED: Homo sapiens transmembrane protein 178A (TMEM178A), transcript variant X8, mRNA.","division":"RefSeq","geneid":"130733","gi":"","length":"4492","nt_position":[],"snippet":"id=\"XP_054196558.1\" /db_xref=\"GeneID:130733\" /db_xref=\"HGNC:HGNC:28517\" /translation=\"MAVAVLLCGCIVATVSFFWEESLTQHVAGLLFLMTGIFCTISLCTYAASISYDLNRLPKLIYSLPADVEHGYSWSIFCAWCSLGFIVAAGGLCIAYPFISRTKIAQLKSGRDSTV\" misc_feature <3436..3708 /gene=\"TMEM178A\" /gene_synonym=\"TMEM178\" /note=\"PMP-22/EMP/MP20/Claudin family; Region: PMP22_Claudin; cl21598\" /db_xref=\"CDD:473919\" ORIGIN //...","source":"Homo sapiens (human)","symbol":"TMEM178A","synonym":"TMEM178","version":"XM_054340583.1"},{"aa_position":[],"accession":"XM_054340586","definition":"PREDICTED: Homo sapiens transmembrane protein 178A (TMEM178A), transcript variant X6, mRNA.","division":"RefSeq","geneid":"130733","gi":"","length":"14794","nt_position":[],"snippet":"id=\"XP_054196561.1\" /db_xref=\"GeneID:130733\" /db_xref=\"HGNC:HGNC:28517\" /translation=\"MAVAVLLCGCIVATVSFFWEESLTQHVAGLLFLMTGIFCTISLCTYAASISYDLNRLPKLIYSLPADVEHGYSWSIFCAWCSLGFIVAAGGLCIAYPFISRTKIAQLKSGRDSTV\" misc_feature <13738..14010 /gene=\"TMEM178A\" /gene_synonym=\"TMEM178\" /note=\"PMP-22/EMP/MP20/Claudin family; Region: PMP22_Claudin; cl21598\" /db_xref=\"CDD:473919\" ORIGIN //...","source":"Homo sapiens (human)","symbol":"TMEM178A","synonym":"TMEM178","version":"XM_054340586.1"},{"aa_position":[],"accession":"XM_054356978","definition":"PREDICTED: Homo sapiens transmembrane protein 178B (TMEM178B), transcript variant X2, mRNA.","division":"RefSeq","geneid":"100507421","gi":"","length":"3982","nt_position":[],"snippet":"MAAGRLLLYTGLSLALCALGMLAVAICSDHWYETDARKHRDRCKAFNTRRVDPGFIYLPLRASRSRLDRWEGKLLRARNRRQLFAMSPADECSRQYNSTNMGLWRKCHRQGFDPEIAALIRKGEIERCTYIKYHYSSATIPRNLTFNITKTIRQDEWHALHLRRMTAGFMGMAVAIILFGWIIGVLGCCWDRGLMQYVAGLLFLMGGKTGGIKECLPQPGQG\" misc_feature 545..>898 /gene=\"TMEM178B\" /note=\"PMP-22/EMP/MP20/Claudin family; Region: PMP22_Claudin; cl21598\" /db_xref=\"CDD:473919\" ORIGIN //...","source":"Homo sapiens (human)","symbol":"TMEM178B","synonym":"","version":"XM_054356978.1"},{"aa_position":[],"accession":"XM_054321079","definition":"PREDICTED: Homo sapiens natural killer cell granule protein 7 (NKG7), transcript variant X2, mRNA.","division":"RefSeq","geneid":"4818","gi":"","length":"627","nt_position":[],"snippet":"GeneID:4818\" /db_xref=\"HGNC:HGNC:7830\" /db_xref=\"MIM:606008\" /translation=\"MELCRSLALLGGSLGLMFCLIALSTDFWFEAVGPTHSAHSGLWPTGHGDIISAISMVVAMAVYTSERWDQPPHPQIQTFFSWSFYLGWVSAILLLCTGALSLGAHCGGPRPGYETL\" misc_feature <267..419 /gene=\"NKG7\" /gene_synonym=\"GIG1; GMP-17; p15-TIA-1\" /note=\"PMP-22/EMP/MP20/Claudin family; Region: PMP22_Claudin; cl21598\" /db_xref=\"CDD:473919\" ORIGIN //...","source":"Homo sapiens (human)","symbol":"NKG7","synonym":"GIG1; GMP-17; p15-TIA-1","version":"XM_054321079.1"},{"aa_position":[],"accession":"XM_054356977","definition":"PREDICTED: Homo sapiens transmembrane protein 178B (TMEM178B), transcript variant X4, mRNA.","division":"RefSeq","geneid":"100507421","gi":"","length":"14666","nt_position":[],"snippet":"misc_feature 545..>901 /gene=\"TMEM178B\" /note=\"PMP-22/EMP/MP20/Claudin family; Region: PMP22_Claudin; cl21598\" /db_xref=\"CDD:473919\" ORIGIN //...","source":"Homo sapiens (human)","symbol":"TMEM178B","synonym":"","version":"XM_054356977.1"},{"aa_position":[],"accession":"XM_054340594","definition":"PREDICTED: Homo sapiens transmembrane protein 182 (TMEM182), transcript variant X1, mRNA.","division":"RefSeq","geneid":"130827","gi":"","length":"1083","nt_position":[],"snippet":"translation=\"MRLNIAIFFGALFGALGVLLFLVAFGSDYWLLATEVGRCSGEKNIENVTFHHEGFFWRCWFNGIVEENDSNIWKFWYTNQPPSKNCTHAYLSPYPFMRGEHNSTSYDSAVIYRGFWAVLMLLGVVAVVIASFLIICAAPFASHFLYKAGGGSYIAADGISSLCYSSLSKSLLSQPLRETSSAINDISLLQALMPLLGWTSHWTCITVGLY\" misc_feature 230..>655 /gene=\"TMEM182\" /note=\"PMP-22/EMP/MP20/Claudin tight junction; Region: Claudin_2; pfam13903\" /db_xref=\"CDD:372799\" polyA_site 1083 /gene=\"TMEM182\" /experiment=\"COORDINATES: polyA evidence [ECO:0006239]\" ORIGIN //...","source":"Homo sapiens (human)","symbol":"TMEM182","synonym":"","version":"XM_054340594.1"},{"aa_position":[],"accession":"XM_054340580","definition":"PREDICTED: Homo sapiens transmembrane protein 178A (TMEM178A), transcript variant X3, mRNA.","division":"RefSeq","geneid":"130733","gi":"","length":"1412","nt_position":[],"snippet":"misc_feature 131..628 /gene=\"TMEM178A\" /gene_synonym=\"TMEM178\" /note=\"PMP-22/EMP/MP20/Claudin family; Region: PMP22_Claudin; cl21598\" /db_xref=\"CDD:473919\" ORIGIN //...","source":"Homo sapiens (human)","symbol":"TMEM178A","synonym":"TMEM178","version":"XM_054340580.1"},{"aa_position":[],"accession":"XM_054320174","definition":"PREDICTED: Homo sapiens epithelial membrane protein 3 (MAM blood group) (EMP3), transcript variant X1, mRNA.","division":"RefSeq","geneid":"2014","gi":"","length":"712","nt_position":[],"snippet":"HGNC:HGNC:3335\" /db_xref=\"MIM:602335\" /translation=\"MSLLLLVVSALHILILILLFVATLDKSWWTLPGKESLNLWYDCTWNNDTKTWACSNVSENGWLKAVQVLMVLSLILCCLSFILFMFQLYTMRRGGLFYATGLCQLCTSVAVFTGALIYAIHAEEILEKHPRGGSFGYCFALAWVAFPLALVSGIIYIHLRKRE\" misc_feature 195..605 /gene=\"EMP3\" /gene_synonym=\"YMP\" /note=\"PMP-22/EMP/MP20/Claudin family; Region: PMP22_Claudin; cl21598\" /db_xref=\"CDD:473919\" ORIGIN //...","source":"Homo sapiens (human)","symbol":"EMP3","synonym":"YMP","version":"XM_054320174.1"},{"aa_position":[],"accession":"XM_054315740","definition":"PREDICTED: Homo sapiens transmembrane protein 235 (TMEM235), transcript variant X6, mRNA.","division":"RefSeq","geneid":"283999","gi":"","length":"958","nt_position":[],"snippet":"misc_feature 299..>625 /gene=\"TMEM235\" /gene_synonym=\"ARGM1\" /note=\"PMP-22/EMP/MP20/Claudin family; Region: PMP22_Claudin; cl21598\" /db_xref=\"CDD:473919\" ORIGIN //...","source":"Homo sapiens (human)","symbol":"TMEM235","synonym":"ARGM1","version":"XM_054315740.1"},{"aa_position":[],"accession":"XM_054315739","definition":"PREDICTED: Homo sapiens transmembrane protein 235 (TMEM235), transcript variant X5, mRNA.","division":"RefSeq","geneid":"283999","gi":"","length":"1916","nt_position":[],"snippet":"misc_feature 299..>625 /gene=\"TMEM235\" /gene_synonym=\"ARGM1\" /note=\"PMP-22/EMP/MP20/Claudin family; Region: PMP22_Claudin; cl21598\" /db_xref=\"CDD:473919\" ORIGIN //...","source":"Homo sapiens (human)","symbol":"TMEM235","synonym":"ARGM1","version":"XM_054315739.1"},{"aa_position":[],"accession":"XM_054316517","definition":"PREDICTED: Homo sapiens peripheral myelin protein 22 (PMP22), transcript variant X2, mRNA.","division":"RefSeq","geneid":"5376","gi":"","length":"543","nt_position":[],"snippet":"HGNC:9118\" /db_xref=\"MIM:601097\" /translation=\"MSIIVLHVAVLVLLFVSTIVSQWIVGNGHATDLWQNCSTSSSGNVHHCFSSSPNEWLQSVQATMILSIIFSILSLFLFFCQLFTLTKGGRFYITGIFQILAESNSSQMCGYRD\" misc_feature 222..>476 /gene=\"PMP22\" /gene_synonym=\"CIDP; CMT1A; CMT1E; DSS; GAS-3; GAS3; HMSNIA; HNPP; Sp110\" /note=\"PMP-22/EMP/MP20/Claudin family; Region: PMP22_Claudin; cl21598\" /db_xref=\"CDD:473919\" ORIGIN //...","source":"Homo sapiens (human)","symbol":"PMP22","synonym":"CIDP; CMT1A; CMT1E; DSS; GAS-3; GAS3; HMSNIA; HNPP; Sp110","version":"XM_054316517.1"},{"aa_position":[],"accession":"XM_054315736","definition":"PREDICTED: Homo sapiens transmembrane protein 235 (TMEM235), transcript variant X2, mRNA.","division":"RefSeq","geneid":"283999","gi":"","length":"2281","nt_position":[],"snippet":"misc_feature 496..1005 /gene=\"TMEM235\" /gene_synonym=\"ARGM1\" /note=\"PMP-22/EMP/MP20/Claudin tight junction; Region: Claudin_2; pfam13903\" /db_xref=\"CDD:372799\" ORIGIN //...","source":"Homo sapiens (human)","symbol":"TMEM235","synonym":"ARGM1","version":"XM_054315736.1"},{"aa_position":[],"accession":"XM_054315738","definition":"PREDICTED: Homo sapiens transmembrane protein 235 (TMEM235), transcript variant X4, mRNA.","division":"RefSeq","geneid":"283999","gi":"","length":"2159","nt_position":[],"snippet":"misc_feature 299..883 /gene=\"TMEM235\" /gene_synonym=\"ARGM1\" /note=\"PMP-22/EMP/MP20/Claudin tight junction; Region: Claudin_2; pfam13903\" /db_xref=\"CDD:372799\" ORIGIN //...","source":"Homo sapiens (human)","symbol":"TMEM235","synonym":"ARGM1","version":"XM_054315738.1"},{"aa_position":[],"accession":"XM_054315737","definition":"PREDICTED: Homo sapiens transmembrane protein 235 (TMEM235), transcript variant X3, mRNA.","division":"RefSeq","geneid":"283999","gi":"","length":"2148","nt_position":[],"snippet":"misc_feature 299..883 /gene=\"TMEM235\" /gene_synonym=\"ARGM1\" /note=\"PMP-22/EMP/MP20/Claudin tight junction; Region: Claudin_2; pfam13903\" /db_xref=\"CDD:372799\" ORIGIN //...","source":"Homo sapiens (human)","symbol":"TMEM235","synonym":"ARGM1","version":"XM_054315737.1"},{"aa_position":[],"accession":"XM_054324980","definition":"PREDICTED: Homo sapiens calcium voltage-gated channel auxiliary subunit gamma 2 (CACNG2), transcript variant X1, mRNA.","division":"RefSeq","geneid":"10369","gi":"","length":"4312","nt_position":[],"snippet":"misc_feature <145..438 /gene=\"CACNG2\" /gene_synonym=\"MRD10\" /note=\"PMP-22/EMP/MP20/Claudin family; Region: PMP22_Claudin; cl21598\" /db_xref=\"CDD:473919\" ORIGIN //...","source":"Homo sapiens (human)","symbol":"CACNG2","synonym":"MRD10","version":"XM_054324980.1"},{"aa_position":[],"accession":"XM_054315735","definition":"PREDICTED: Homo sapiens transmembrane protein 235 (TMEM235), transcript variant X1, mRNA.","division":"RefSeq","geneid":"283999","gi":"","length":"2235","nt_position":[],"snippet":"misc_feature 299..970 /gene=\"TMEM235\" /gene_synonym=\"ARGM1\" /note=\"PMP-22/EMP/MP20/Claudin tight junction; Region: Claudin_2; pfam13903\" /db_xref=\"CDD:372799\" ORIGIN //...","source":"Homo sapiens (human)","symbol":"TMEM235","synonym":"ARGM1","version":"XM_054315735.1"},{"aa_position":[],"accession":"XM_054316516","definition":"PREDICTED: Homo sapiens peripheral myelin protein 22 (PMP22), transcript variant X1, mRNA.","division":"RefSeq","geneid":"5376","gi":"","length":"3312","nt_position":[],"snippet":"db_xref=\"MIM:601097\" /translation=\"MSIIVLHVAVLVLLFVSTIVSQWIVGNGHATDLWQNCSTSSSGNVHHCFSSSPNEWLQSVQATMILSIIFSILSLFLFFCQLFTLTKGGRFYITGIFQILAALPSLDKSDRAQETTSVFLKDKS\" misc_feature 222..>491 /gene=\"PMP22\" /gene_synonym=\"CIDP; CMT1A; CMT1E; DSS; GAS-3; GAS3; HMSNIA; HNPP; Sp110\" /note=\"PMP-22/EMP/MP20/Claudin family; Region: PMP22_Claudin; cl21598\" /db_xref=\"CDD:473919\" polyA_site 3312 /gene=\"PMP22\" /gene_synonym=\"CIDP; CMT1A; CMT1E; DSS; GAS-3; GAS3; HMSNIA; HNPP; Sp110\" /experiment=\"COORDINATES: polyA evidence [ECO:0006239]\" ORIGIN //...","source":"Homo sapiens (human)","symbol":"PMP22","synonym":"CIDP; CMT1A; CMT1E; DSS; GAS-3; GAS3; HMSNIA; HNPP; Sp110","version":"XM_054316516.1"},{"aa_position":[],"accession":"XM_054379666","definition":"PREDICTED: Homo sapiens GSG1 like (GSG1L), transcript variant X1, mRNA.","division":"RefSeq","geneid":"146395","gi":"","length":"1331","nt_position":[],"snippet":"misc_feature 360..686 /gene=\"GSG1L\" /gene_synonym=\"PRO19651\" /note=\"GSG1-like protein; Region: GSG-1; pfam07803\" /db_xref=\"CDD:462270\" misc_feature <594..995 /gene=\"GSG1L\" /gene_synonym=\"PRO19651\" /note=\"PMP-22/EMP/MP20/Claudin family; Region: PMP22_Claudin; cl21598\" /db_xref=\"CDD:473919\" ORIGIN //...","source":"Homo sapiens (human)","symbol":"GSG1L","synonym":"PRO19651","version":"XM_054379666.1"},{"aa_position":[],"accession":"NM_001101389","definition":"Homo sapiens claudin 25 (CLDN25), mRNA.","division":"RefSeq","geneid":"644672","gi":"","length":"690","nt_position":[],"snippet":"CH471065.1. On or before Oct 4, 2007 this sequence version replaced XM_927777.1, XM_938396.1. Summary: This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent...function of claudins JOURNAL Biochim Biophys Acta 1778 (3), 631-645 (2008) PUBMED 18036336 REMARK Review article REFERENCE 5 (bases 1 to 690) AUTHORS Katoh,M. and Katoh,M. TITLE CLDN23 gene, frequently down-regulated in intestinal-type gastric cancer, is a novel member of CLAUDIN gene family JOURNAL...","source":"Homo sapiens (human)","symbol":"CLDN25","synonym":"","version":"NM_001101389.1"},{"aa_position":[],"accession":"NM_001185149","definition":"Homo sapiens claudin 24 (CLDN24), mRNA.","division":"RefSeq","geneid":"100132463","gi":"","length":"663","nt_position":[],"snippet":"Jun 9, 2010 this sequence version replaced XM_001714660.1, XM_001716940.1, XM_001716970.1. Summary: This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent...function of claudins JOURNAL Biochim Biophys Acta 1778 (3), 631-645 (2008) PUBMED 18036336 REMARK Review article REFERENCE 3 (bases 1 to 663) AUTHORS Katoh,M. and Katoh,M. TITLE CLDN23 gene, frequently down-regulated in intestinal-type gastric cancer, is a novel member of CLAUDIN gene family JOURNAL...","source":"Homo sapiens (human)","symbol":"CLDN24","synonym":"CLDN21","version":"NM_001185149.1"},{"aa_position":[],"accession":"XM_047438140","definition":"PREDICTED: Homo sapiens claudin domain containing 2 (CLDND2), transcript variant X4, mRNA.","division":"RefSeq","geneid":"125875","gi":"","length":"601","nt_position":[],"snippet":"replace=\"c\" /replace=\"t\" /db_xref=\"dbSNP:2514179243\" CDS 54..557 /gene=\"CLDND2\" /codon_start=1 /product=\"claudin domain-containing protein 2 isoform X2\" /protein_id=\"XP_047294096.1\" /db_xref=\"GeneID:125875\" /db_xref=\"HGNC:HGNC:28511\" /translation=\"MGVKRSLQSGGILLSLVANVLMVLSTATNYWTRQQEGHSGLWQECNHGICSSIPCQTTLAVTVACMVLAVGVGVVGMVMGLRIRCDEGESLRGQTTSAFLFLGGLLLLTALIGYTVKNAWKNNVFFSWSYFSGWLALPFSILAGFCFLLADMIMQSTDAISGFPVCL\" misc_feature 81..485 /gene=\"CLDND2\" /note=\"PMP-22/EMP/MP20/Claudin family; Region: PMP22_Claudin; cl21598\" /db_xref=\"CDD:473919\" variation 55 /gene=\"CLDND2\" /replace=\"c\" /replace=\"g...","source":"Homo sapiens (human)","symbol":"CLDND2","synonym":"","version":"XM_047438140.1"},{"aa_position":[],"accession":"NM_014343","definition":"Homo sapiens claudin 15 (CLDN15), transcript variant 2, mRNA.","division":"RefSeq","geneid":"24146","gi":"","length":"1224","nt_position":[],"snippet":"s claudin 15 (CLDN15), transcript variant 2, mRNA. ACCESSION NM_014343 VERSION NM_014343.3 KEYWORDS RefSeq; MANE Select. SOURCE Homo sapiens (human) ORGANISM Homo sapiens Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. REFERENCE COMMENT REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AJ245738.1 and AK056103.1. On Jun 2, 2019 this sequence version replaced NM_014343.2. Summary: This gene encodes a member of the claudin family. Claudins...","source":"Homo sapiens (human)","symbol":"CLDN15","synonym":"","version":"NM_014343.3"},{"aa_position":[],"accession":"XM_047438139","definition":"PREDICTED: Homo sapiens claudin domain containing 2 (CLDND2), transcript variant X3, mRNA.","division":"RefSeq","geneid":"125875","gi":"","length":"614","nt_position":[],"snippet":"replace=\"c\" /replace=\"t\" /db_xref=\"dbSNP:2514179243\" CDS 67..570 /gene=\"CLDND2\" /codon_start=1 /product=\"claudin domain-containing protein 2 isoform X2\" /protein_id=\"XP_047294095.1\" /db_xref=\"GeneID:125875\" /db_xref=\"HGNC:HGNC:28511\" /translation=\"MGVKRSLQSGGILLSLVANVLMVLSTATNYWTRQQEGHSGLWQECNHGICSSIPCQTTLAVTVACMVLAVGVGVVGMVMGLRIRCDEGESLRGQTTSAFLFLGGLLLLTALIGYTVKNAWKNNVFFSWSYFSGWLALPFSILAGFCFLLADMIMQSTDAISGFPVCL\" misc_feature 94..498 /gene=\"CLDND2\" /note=\"PMP-22/EMP/MP20/Claudin family; Region: PMP22_Claudin; cl21598\" /db_xref=\"CDD:473919\" variation 68 /gene=\"CLDND2\" /replace=\"c\" /replace=\"g...","source":"Homo sapiens (human)","symbol":"CLDND2","synonym":"","version":"XM_047438139.1"},{"aa_position":[],"accession":"NM_012131","definition":"Homo sapiens claudin 17 (CLDN17), mRNA.","division":"RefSeq","geneid":"26285","gi":"","length":"1241","nt_position":[],"snippet":"sapiens claudin 17 (CLDN17), mRNA. ACCESSION NM_012131 VERSION NM_012131.3 KEYWORDS RefSeq; MANE Select. SOURCE Homo sapiens (human) ORGANISM Homo sapiens Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. REFERENCE COMMENT REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AP000884.1 and BC101503.1. On May 17, 2019 this sequence version replaced NM_012131.2. Summary: This gene encodes a member of the claudin family. Claudins are integral...","source":"Homo sapiens (human)","symbol":"CLDN17","synonym":"","version":"NM_012131.3"},{"aa_position":[],"accession":"NM_001001346","definition":"Homo sapiens claudin 20 (CLDN20), mRNA.","division":"RefSeq","geneid":"49861","gi":"","length":"1209","nt_position":[],"snippet":"sapiens claudin 20 (CLDN20), mRNA. ACCESSION NM_001001346 VERSION NM_001001346.3 KEYWORDS RefSeq; MANE Select. SOURCE Homo sapiens (human) ORGANISM Homo sapiens Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. REFERENCE COMMENT REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC020838.1 and AL139101.13. On Jun 5, 2010 this sequence version replaced NM_001001346.2. Summary: This gene encodes a member of the claudin family. Claudins are...","source":"Homo sapiens (human)","symbol":"CLDN20","synonym":"","version":"NM_001001346.3"},{"aa_position":[],"accession":"NM_012130","definition":"Homo sapiens claudin 14 (CLDN14), transcript variant epsilon, mRNA.","division":"RefSeq","geneid":"23562","gi":"","length":"1257","nt_position":[],"snippet":"LOCUS NM_012130 1257 bp mRNA linear PRI 20-NOV-2025 DEFINITION Homo sapiens claudin 14 (CLDN14), transcript variant epsilon, mRNA. ACCESSION NM_012130 VERSION NM_012130.4 KEYWORDS RefSeq. SOURCE Homo sapiens (human) ORGANISM Homo sapiens Eukaryota; Metazoa; Chordata; Craniata; Vertebrata;...from UniProtKB/Swiss-Prot (O95500.1); transmembrane region\" misc_feature 249..725 /gene=\"CLDN14\" /gene_synonym=\"DFNB29\" /note=\"PMP-22/EMP/MP20/Claudin family; Region: PMP22_Claudin; cl21598\" /db_xref=\"CDD:473919\" misc_feature 426..488 /gene=\"CLDN14\" /gene_synonym=\"DFNB29\" /note=\"propagated from...","source":"Homo sapiens (human)","symbol":"CLDN14","synonym":"DFNB29","version":"NM_012130.4"},{"aa_position":[],"accession":"NM_001412134","definition":"Homo sapiens calcium voltage-gated channel auxiliary subunit gamma 7 (CACNG7), transcript variant 3, mRNA.","division":"RefSeq","geneid":"59284","gi":"","length":"2607","nt_position":[],"snippet":"misc_feature 291..353 /gene=\"CACNG7\" /note=\"propagated from UniProtKB/Swiss-Prot (P62955.1); transmembrane region\" misc_feature 321..>698 /gene=\"CACNG7\" /note=\"PMP-22/EMP/MP20/Claudin family; Region: PMP22_Claudin; cl21598\" /db_xref=\"CDD:473919\" misc_feature 576..638 /gene=\"CACNG7\" /note=\"propagated from UniProtKB/Swiss-Prot (P62955.1); transmembrane region\" exon 466..552 /gene=\"CACNG7\" /inference=\"alignment:Splign:2.1.0\" exon 553..693 /gene=\"CACNG7\" /inference=\"alignment:Splign:2.1.0\" exon 694..2607 /gene=\"CACNG7\" /inference=\"alignment:Splign:2.1.0\" regulatory 2353..2358 /regulatory_class=\"...","source":"Homo sapiens (human)","symbol":"CACNG7","synonym":"","version":"NM_001412134.1"},{"aa_position":[],"accession":"NM_001185080","definition":"Homo sapiens claudin 15 (CLDN15), transcript variant 1, mRNA.","division":"RefSeq","geneid":"24146","gi":"","length":"2129","nt_position":[],"snippet":"ens claudin 15 (CLDN15), transcript variant 1, mRNA. ACCESSION NM_001185080 VERSION NM_001185080.2 KEYWORDS RefSeq. SOURCE Homo sapiens (human) ORGANISM Homo sapiens Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. REFERENCE COMMENT REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK056103.1 and DB158141.1. On Aug 13, 2020 this sequence version replaced NM_001185080.1. Summary: This gene encodes a member of the claudin family. Claudins...","source":"Homo sapiens (human)","symbol":"CLDN15","synonym":"","version":"NM_001185080.2"},{"aa_position":[],"accession":"NM_001146077","definition":"Homo sapiens claudin 14 (CLDN14), transcript variant 3, mRNA.","division":"RefSeq","geneid":"23562","gi":"","length":"1453","nt_position":[],"snippet":"LOCUS NM_001146077 1453 bp mRNA linear PRI 21-NOV-2025 DEFINITION Homo sapiens claudin 14 (CLDN14), transcript variant 3, mRNA. ACCESSION NM_001146077 VERSION NM_001146077.2 KEYWORDS RefSeq. SOURCE Homo sapiens (human) ORGANISM Homo sapiens Eukaryota; Metazoa; Chordata; Craniata; Vertebrata;...from UniProtKB/Swiss-Prot (O95500.1); transmembrane region\" misc_feature 445..921 /gene=\"CLDN14\" /gene_synonym=\"DFNB29\" /note=\"PMP-22/EMP/MP20/Claudin family; Region: PMP22_Claudin; cl21598\" /db_xref=\"CDD:473919\" misc_feature 622..684 /gene=\"CLDN14\" /gene_synonym=\"DFNB29\" /note=\"propagated from...","source":"Homo sapiens (human)","symbol":"CLDN14","synonym":"DFNB29","version":"NM_001146077.2"},{"aa_position":[],"accession":"NM_001306","definition":"Homo sapiens claudin 3 (CLDN3), mRNA.","division":"RefSeq","geneid":"1365","gi":"","length":"1274","nt_position":[],"snippet":"prostate.1 protein homolog\" /codon_start=1 /product=\"claudin-3\" /protein_id=\"NP_001297.1\" /db_xref=\"CCDS:CCDS5559.1\" /db_xref=\"GeneID:1365\" /db_xref=\"HGNC:HGNC:2045\" /db_xref=\"MIM:602910\" /translation=\"MSMGLEITGTALAVLGWLGTIVCCALPMWRVSAFIGSNIITSQNIWEGLWMNCVVQSTGQMQCKVYDSLLALPQDLQAARALIVVAILLAAFGLLVALVGAQCTNCVQDDTAKAKITIVAGVLFLLAALLTLVPVSWSANTIIRDFYNPVVPEAQKREMGAGLYVGWAAAALQLLGGALLCCSCPPREKKYTATKVVYSAPRSTGPGASLGTGYDRKDYV\" misc_feature 228..722 /gene=\"CLDN3\" /gene_synonym=\"C7orf1; CPE-R2; CPETR2; HRVP1; RVP1\" /note=\"PMP-22/EMP/MP20/Claudin family; Region: PMP22_Claudin; cl21598\" /db_xref=\"CDD...","source":"Homo sapiens (human)","symbol":"CLDN3","synonym":"C7orf1; CPE-R2; CPETR2; HRVP1; RVP1","version":"NM_001306.4"},{"aa_position":[],"accession":"NM_001146078","definition":"Homo sapiens claudin 14 (CLDN14), transcript variant gamma, mRNA.","division":"RefSeq","geneid":"23562","gi":"","length":"1514","nt_position":[],"snippet":"LOCUS NM_001146078 1514 bp mRNA linear PRI 20-NOV-2025 DEFINITION Homo sapiens claudin 14 (CLDN14), transcript variant gamma, mRNA. ACCESSION NM_001146078 VERSION NM_001146078.3 KEYWORDS RefSeq. SOURCE Homo sapiens (human) ORGANISM Homo sapiens Eukaryota; Metazoa; Chordata; Craniata; Vertebrata;...from UniProtKB/Swiss-Prot (O95500.1); transmembrane region\" misc_feature 506..982 /gene=\"CLDN14\" /gene_synonym=\"DFNB29\" /note=\"PMP-22/EMP/MP20/Claudin family; Region: PMP22_Claudin; cl21598\" /db_xref=\"CDD:473919\" misc_feature 683..745 /gene=\"CLDN14\" /gene_synonym=\"DFNB29\" /note=\"propagated from...","source":"Homo sapiens (human)","symbol":"CLDN14","synonym":"DFNB29","version":"NM_001146078.3"},{"aa_position":[],"accession":"NM_001195081","definition":"Homo sapiens claudin 34 (CLDN34), mRNA.","division":"RefSeq","geneid":"100288814","gi":"","length":"995","nt_position":[],"snippet":"LOCUS NM_001195081 995 bp mRNA linear PRI 28-APR-2025 DEFINITION Homo sapiens claudin 34 (CLDN34), mRNA. ACCESSION NM_001195081 XM_002343807 XM_002348146 VERSION NM_001195081.2 KEYWORDS RefSeq; MANE Select. SOURCE Homo sapiens (human) ORGANISM Homo sapiens Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. REFERENCE COMMENT VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC002365.1. On May 17, 2019 this sequence version...","source":"Homo sapiens (human)","symbol":"CLDN34","synonym":"","version":"NM_001195081.2"},{"aa_position":[],"accession":"NM_021195","definition":"Homo sapiens claudin 6 (CLDN6), mRNA.","division":"RefSeq","geneid":"9074","gi":"","length":"1366","nt_position":[],"snippet":"CDS 57..719 /gene=\"CLDN6\" /note=\"skullin\" /codon_start=1 /product=\"claudin-6\" /protein_id=\"NP_067018.2\" /db_xref=\"CCDS:CCDS10488.1\" /db_xref=\"GeneID:9074\" /db_xref=\"HGNC:HGNC:2048\" /db_xref=\"MIM:615798\" /translation=\"MASAGMQILGVVLTLLGWVNGLVSCALPMWKVTAFIGNSIVVAQVVWEGLWMSCVVQSTGQMQCKVYDSLLALPQDLQAARALCVIALLVALFGLLVYLAGAKCTTCVEEKDSKARLVLTSGIVFVISGVLTLIPVCWTAHAIIRDFYNPLVAEAQKRELGASLYLGWAASGLLLLGGGLLCCTCPSGGSQGPSHYMARYSTSAPAISRGPSEYPTKNYV\" misc_feature 69..566 /gene=\"CLDN6\" /note=\"PMP-22/EMP/MP20/Claudin family; Region: PMP22_Claudin; cl21598\" /db_xref=\"CDD:473919\" misc_feature 78..140 /gene=\"...","source":"Homo sapiens (human)","symbol":"CLDN6","synonym":"","version":"NM_021195.5"},{"aa_position":[],"accession":"NR_029638","definition":"Homo sapiens microRNA 224 (MIR224), microRNA.","division":"RefSeq","geneid":"407009","gi":"","length":"81","nt_position":[],"snippet":". REFERENCE 2 (bases 1 to 81) AUTHORS Yang,L., Wu,W.J., Lyu,L.C., Tu,Y., Gu,H., Chen,X.F., Chai,Y.J., Man,M.Q. and He,L. TITLE MiRNA-224-5p regulates the defective permeability barrier in sensitive skin by targeting claudin-5 JOURNAL Skin Res Technol 30 (5), e13720 (2024) PUBMED 38743384 REMARK GeneRIF: MiRNA-224-5p regulates the defective permeability barrier in sensitive skin by targeting claudin-5. REFERENCE 3 (bases 1 to 81) AUTHORS Wang,Q., Zhang,G., Zhang,M., Zhang,Y., Ruan,L. and Hao,H. TITLE...","source":"Homo sapiens (human)","symbol":"MIR224","synonym":"MIRN224; miRNA224","version":"NR_029638.1"},{"aa_position":[],"accession":"NM_001146079","definition":"Homo sapiens claudin 14 (CLDN14), transcript variant 5, mRNA.","division":"RefSeq","geneid":"23562","gi":"","length":"1784","nt_position":[],"snippet":"LOCUS NM_001146079 1784 bp mRNA linear PRI 20-NOV-2025 DEFINITION Homo sapiens claudin 14 (CLDN14), transcript variant 5, mRNA. ACCESSION NM_001146079 VERSION NM_001146079.2 KEYWORDS RefSeq; MANE Select. SOURCE Homo sapiens (human) ORGANISM Homo sapiens Eukaryota; Metazoa; Chordata; Craniata;...from UniProtKB/Swiss-Prot (O95500.1); transmembrane region\" misc_feature 776..1252 /gene=\"CLDN14\" /gene_synonym=\"DFNB29\" /note=\"PMP-22/EMP/MP20/Claudin family; Region: PMP22_Claudin; cl21598\" /db_xref=\"CDD:473919\" misc_feature 953..1015 /gene=\"CLDN14\" /gene_synonym=\"DFNB29\" /note=\"propagated from...","source":"Homo sapiens (human)","symbol":"CLDN14","synonym":"DFNB29","version":"NM_001146079.2"},{"aa_position":[],"accession":"NM_001410743","definition":"Homo sapiens occludin (OCLN), transcript variant 4, mRNA.","division":"RefSeq","geneid":"100506658","gi":"","length":"6021","nt_position":[],"snippet":"is overexpressed in tubo-ovarian high-grade serous carcinoma compared to mesothelioma and is a marker of tumor progression and chemoresistance. REFERENCE 3 (bases 1 to 6021) AUTHORS So,C.W., Sourisseau,M., Sarwar,S., Evans,M.J. and Randall,G. TITLE Roles of epidermal growth factor receptor, claudin-1 and occludin in multi-step entry of hepatitis C virus into polarized hepatoma spheroids JOURNAL PLoS Pathog 19 (12), e1011887 (2023) PUBMED 38157366 REMARK GeneRIF: Roles of epidermal growth factor receptor, claudin-1 and occludin in multi-step entry of hepatitis C virus into polarized hepatoma...","source":"Homo sapiens (human)","symbol":"OCLN","synonym":"BLCPMG; PPP1R115; PTORCH1","version":"NM_001410743.1"},{"aa_position":[],"accession":"NM_001205255","definition":"Homo sapiens occludin (OCLN), transcript variant 3, mRNA.","division":"RefSeq","geneid":"100506658","gi":"","length":"5502","nt_position":[],"snippet":"is overexpressed in tubo-ovarian high-grade serous carcinoma compared to mesothelioma and is a marker of tumor progression and chemoresistance. REFERENCE 3 (bases 1 to 5502) AUTHORS So,C.W., Sourisseau,M., Sarwar,S., Evans,M.J. and Randall,G. TITLE Roles of epidermal growth factor receptor, claudin-1 and occludin in multi-step entry of hepatitis C virus into polarized hepatoma spheroids JOURNAL PLoS Pathog 19 (12), e1011887 (2023) PUBMED 38157366 REMARK GeneRIF: Roles of epidermal growth factor receptor, claudin-1 and occludin in multi-step entry of hepatitis C virus into polarized hepatoma...","source":"Homo sapiens (human)","symbol":"OCLN","synonym":"BLCPMG; PPP1R115; PTORCH1","version":"NM_001205255.2"},{"aa_position":[],"accession":"NM_001438048","definition":"Homo sapiens occludin (OCLN), transcript variant 5, mRNA.","division":"RefSeq","geneid":"100506658","gi":"","length":"6019","nt_position":[],"snippet":"is overexpressed in tubo-ovarian high-grade serous carcinoma compared to mesothelioma and is a marker of tumor progression and chemoresistance. REFERENCE 3 (bases 1 to 6019) AUTHORS So,C.W., Sourisseau,M., Sarwar,S., Evans,M.J. and Randall,G. TITLE Roles of epidermal growth factor receptor, claudin-1 and occludin in multi-step entry of hepatitis C virus into polarized hepatoma spheroids JOURNAL PLoS Pathog 19 (12), e1011887 (2023) PUBMED 38157366 REMARK GeneRIF: Roles of epidermal growth factor receptor, claudin-1 and occludin in multi-step entry of hepatitis C virus into polarized hepatoma...","source":"Homo sapiens (human)","symbol":"OCLN","synonym":"BLCPMG; PPP1R115; PTORCH1","version":"NM_001438048.1"},{"aa_position":[],"accession":"NM_199328","definition":"Homo sapiens claudin 8 (CLDN8), mRNA.","division":"RefSeq","geneid":"9073","gi":"","length":"2092","nt_position":[],"snippet":"been curated by NCBI staff. The reference sequence was derived from DA629490.1, AY358707.1, AL049977.1 and AW235670.1. This sequence is a reference standard in the RefSeqGene project. On May 17, 2019 this sequence version replaced NM_199328.2. Summary: This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in...","source":"Homo sapiens (human)","symbol":"CLDN8","synonym":"HEL-S-79","version":"NM_199328.3"},{"aa_position":[],"accession":"NM_144492","definition":"Homo sapiens claudin 14 (CLDN14), transcript variant 1, mRNA.","division":"RefSeq","geneid":"23562","gi":"","length":"1974","nt_position":[],"snippet":"LOCUS NM_144492 1974 bp mRNA linear PRI 20-NOV-2025 DEFINITION Homo sapiens claudin 14 (CLDN14), transcript variant 1, mRNA. ACCESSION NM_144492 VERSION NM_144492.3 KEYWORDS RefSeq. SOURCE Homo sapiens (human) ORGANISM Homo sapiens Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;...from UniProtKB/Swiss-Prot (O95500.1); transmembrane region\" misc_feature 966..1442 /gene=\"CLDN14\" /gene_synonym=\"DFNB29\" /note=\"PMP-22/EMP/MP20/Claudin family; Region: PMP22_Claudin; cl21598\" /db_xref=\"CDD:473919\" misc_feature 1143..1205 /gene=\"CLDN14\" /gene_synonym=\"DFNB29\" /note=\"propagated from...","source":"Homo sapiens (human)","symbol":"CLDN14","synonym":"DFNB29","version":"NM_144492.3"},{"aa_position":[],"accession":"XM_047438138","definition":"PREDICTED: Homo sapiens claudin domain containing 2 (CLDND2), transcript variant X2, mRNA.","division":"RefSeq","geneid":"125875","gi":"","length":"1201","nt_position":[],"snippet":"gene=\"CLDND2\" /codon_start=1 /product=\"claudin domain-containing protein 2 isoform X1\" /protein_id=\"XP_047294094.1\" /db_xref=\"GeneID:125875\" /db_xref=\"HGNC:HGNC:28511\" /translation=\"MGVKRSLQSGGILLSLVANVLMVLSTATNYWTRQQEGHSGLWQECNHGICSSIPCQTTLAVTVACMVLAVGVGVVGMVMGLRIRCDEGESLRGQTTSAFLFLGGLLLLTALIGYTVKNAWKNNVFFSWSYFSGWLALPFSILAGKLDSGKRVEETAQKTLTPEAPQLPSQETPGTSRGLPNTLTTPADPAETPLEPQTPVPGALPAIRPRAHLPLPAPHPRPPRLLLSAGRHDHAEHRRHQWIPRVSVTAACLGQNKGTAFFSAAAPRAFLRVVGTQARGCIEAQGRHKDMNS\" misc_feature 81..491 /gene=\"CLDND2\" /note=\"PMP-22/EMP/MP20/Claudin family; Region: PMP22_Claudin; cl21598\" /db_xref=\"CDD...","source":"Homo sapiens (human)","symbol":"CLDND2","synonym":"","version":"XM_047438138.1"},{"aa_position":[],"accession":"XM_047438137","definition":"PREDICTED: Homo sapiens claudin domain containing 2 (CLDND2), transcript variant X1, mRNA.","division":"RefSeq","geneid":"125875","gi":"","length":"1214","nt_position":[],"snippet":"gene=\"CLDND2\" /codon_start=1 /product=\"claudin domain-containing protein 2 isoform X1\" /protein_id=\"XP_047294093.1\" /db_xref=\"GeneID:125875\" /db_xref=\"HGNC:HGNC:28511\" /translation=\"MGVKRSLQSGGILLSLVANVLMVLSTATNYWTRQQEGHSGLWQECNHGICSSIPCQTTLAVTVACMVLAVGVGVVGMVMGLRIRCDEGESLRGQTTSAFLFLGGLLLLTALIGYTVKNAWKNNVFFSWSYFSGWLALPFSILAGKLDSGKRVEETAQKTLTPEAPQLPSQETPGTSRGLPNTLTTPADPAETPLEPQTPVPGALPAIRPRAHLPLPAPHPRPPRLLLSAGRHDHAEHRRHQWIPRVSVTAACLGQNKGTAFFSAAAPRAFLRVVGTQARGCIEAQGRHKDMNS\" misc_feature 94..504 /gene=\"CLDND2\" /note=\"PMP-22/EMP/MP20/Claudin family; Region: PMP22_Claudin; cl21598\" /db_xref=\"CDD...","source":"Homo sapiens (human)","symbol":"CLDND2","synonym":"","version":"XM_047438137.1"},{"aa_position":[],"accession":"NM_001363066","definition":"Homo sapiens claudin 5 (CLDN5), transcript variant 4, mRNA.","division":"RefSeq","geneid":"7122","gi":"","length":"1384","nt_position":[],"snippet":"Hominidae; Homo. REFERENCE COMMENT REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC000082.4, AK124019.1 and BC032363.1. On Jun 2, 2019 this sequence version replaced NM_001363066.1. Summary: This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets. Mutations in this gene have been found in...","source":"Homo sapiens (human)","symbol":"CLDN5","synonym":"AWAL; BEC1; CPETRL1; TMDVCF; TMVCF","version":"NM_001363066.2"},{"aa_position":[],"accession":"NM_152353","definition":"Homo sapiens claudin domain containing 2 (CLDND2), mRNA.","division":"RefSeq","geneid":"125875","gi":"","length":"974","nt_position":[],"snippet":"gene=\"CLDND2\" /codon_start=1 /product=\"claudin domain-containing protein 2\" /protein_id=\"NP_689566.1\" /db_xref=\"CCDS:CCDS12829.1\" /db_xref=\"GeneID:125875\" /db_xref=\"HGNC:HGNC:28511\" /translation=\"MGVKRSLQSGGILLSLVANVLMVLSTATNYWTRQQEGHSGLWQECNHGICSSIPCQTTLAVTVACMVLAVGVGVVGMVMGLRIRCDEGESLRGQTTSAFLFLGGLLLLTALIGYTVKNAWKNNVFFSWSYFSGWLALPFSILAGFCFLLADMIMQSTDAISGFPVCL\" misc_feature 445..507 /gene=\"CLDND2\" /note=\"propagated from UniProtKB/Swiss-Prot (Q8NHS1.1); transmembrane region\" misc_feature 454..858 /gene=\"CLDND2\" /note=\"PMP-22/EMP/MP20/Claudin family; Region: PMP22_Claudin; cl21598\" /db_xref=\"...","source":"Homo sapiens (human)","symbol":"CLDND2","synonym":"","version":"NM_152353.3"},{"aa_position":[],"accession":"NM_001305","definition":"Homo sapiens claudin 4 (CLDN4), mRNA.","division":"RefSeq","geneid":"1364","gi":"","length":"1695","nt_position":[],"snippet":"record has been curated by NCBI staff. The reference sequence was derived from AC093168.3. This sequence is a reference standard in the RefSeqGene project. On Apr 15, 2020 this sequence version replaced NM_001305.4. Summary: The protein encoded by this intronless gene belongs to the claudin family. Claudins are integral membrane proteins that are components of the epithelial cell tight junctions, which regulate movement of solutes and ions through the paracellular space. This protein is a high-affinity receptor for Clostridium perfringens enterotoxin (CPE) and may play a role in internal organ...","source":"Homo sapiens (human)","symbol":"CLDN4","synonym":"CPE-R; CPER; CPETR; CPETR1; hCPE-R; WBSCR8","version":"NM_001305.5"},{"aa_position":[],"accession":"NM_001160100","definition":"Homo sapiens claudin 10 (CLDN10), transcript variant a_v1, mRNA.","division":"RefSeq","geneid":"9071","gi":"","length":"2448","nt_position":[],"snippet":"Homo. REFERENCE COMMENT REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK055855.1, BG697724.1, DB544708.1 and AL139376.17. On Aug 13, 2020 this sequence version replaced NM_001160100.1. Summary: This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in...","source":"Homo sapiens (human)","symbol":"CLDN10","synonym":"CPETRL3; HELIX; OSP-L; OSPL","version":"NM_001160100.2"},{"aa_position":[],"accession":"NM_020982","definition":"Homo sapiens claudin 9 (CLDN9), mRNA.","division":"RefSeq","geneid":"9080","gi":"","length":"1583","nt_position":[],"snippet":"claudin 9 (CLDN9), mRNA. ACCESSION NM_020982 XM_001715692 VERSION NM_020982.4 KEYWORDS RefSeq; MANE Select. SOURCE Homo sapiens (human) ORGANISM Homo sapiens Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. REFERENCE COMMENT REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK091002.1, BC051870.1 and AI791760.1. On Nov 23, 2018 this sequence version replaced NM_020982.3. Summary: This gene encodes a member of the claudin family. Claudins...","source":"Homo sapiens (human)","symbol":"CLDN9","synonym":"DFNB116","version":"NM_020982.4"},{"aa_position":[],"accession":"NM_182848","definition":"Homo sapiens claudin 10 (CLDN10), transcript variant a, mRNA.","division":"RefSeq","geneid":"9071","gi":"","length":"2505","nt_position":[],"snippet":"Homo. REFERENCE COMMENT REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK055855.1, BG697724.1, DB544708.1 and AL139376.17. On Aug 14, 2020 this sequence version replaced NM_182848.3. Summary: This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining...","source":"Homo sapiens (human)","symbol":"CLDN10","synonym":"CPETRL3; HELIX; OSP-L; OSPL","version":"NM_182848.4"},{"aa_position":[],"accession":"NM_006984","definition":"Homo sapiens claudin 10 (CLDN10), transcript variant b, mRNA.","division":"RefSeq","geneid":"9071","gi":"","length":"2466","nt_position":[],"snippet":"The reference sequence was derived from DA133712.1, BC010920.1, AK055855.1, BG697724.1, DB544708.1 and AL139376.17. This sequence is a reference standard in the RefSeqGene project. On Nov 22, 2018 this sequence version replaced NM_006984.4. Summary: This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in...","source":"Homo sapiens (human)","symbol":"CLDN10","synonym":"CPETRL3; HELIX; OSP-L; OSPL","version":"NM_006984.5"},{"aa_position":[],"accession":"XM_011526428","definition":"PREDICTED: Homo sapiens claudin domain containing 2 (CLDND2), transcript variant X5, mRNA.","division":"RefSeq","geneid":"125875","gi":"","length":"1262","nt_position":[],"snippet":"LOCUS XM_011526428 1262 bp mRNA linear PRI 05-AUG-2025 DEFINITION PREDICTED: Homo sapiens claudin domain containing 2 (CLDND2), transcript variant X5, mRNA. ACCESSION XM_011526428 VERSION XM_011526428.3 DBLINK BioProject: PRJNA168 KEYWORDS RefSeq. SOURCE Homo sapiens (human) ORGANISM Homo sapiens Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. COMMENT MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000019.10)...","source":"Homo sapiens (human)","symbol":"CLDND2","synonym":"","version":"XM_011526428.3"},{"aa_position":[],"accession":"NM_001438604","definition":"Homo sapiens occludin (OCLN), transcript variant 6, mRNA.","division":"RefSeq","geneid":"100506658","gi":"","length":"6234","nt_position":[],"snippet":"is overexpressed in tubo-ovarian high-grade serous carcinoma compared to mesothelioma and is a marker of tumor progression and chemoresistance. REFERENCE 3 (bases 1 to 6234) AUTHORS So,C.W., Sourisseau,M., Sarwar,S., Evans,M.J. and Randall,G. TITLE Roles of epidermal growth factor receptor, claudin-1 and occludin in multi-step entry of hepatitis C virus into polarized hepatoma spheroids JOURNAL PLoS Pathog 19 (12), e1011887 (2023) PUBMED 38157366 REMARK GeneRIF: Roles of epidermal growth factor receptor, claudin-1 and occludin in multi-step entry of hepatitis C virus into polarized hepatoma...","source":"Homo sapiens (human)","symbol":"OCLN","synonym":"BLCPMG; PPP1R115; PTORCH1","version":"NM_001438604.1"},{"aa_position":[],"accession":"NM_001002026","definition":"Homo sapiens claudin 18 (CLDN18), transcript variant 2, mRNA.","division":"RefSeq","geneid":"51208","gi":"","length":"3347","nt_position":[],"snippet":"Homo. REFERENCE COMMENT VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK098474.1, BM785703.1 and AY102073.1. On May 31, 2019 this sequence version replaced NM_001002026.2. Summary: This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in...","source":"Homo sapiens (human)","symbol":"CLDN18","synonym":"SFTA5; SFTPJ","version":"NM_001002026.3"},{"aa_position":[],"accession":"NM_003277","definition":"Homo sapiens claudin 5 (CLDN5), transcript variant 2, mRNA.","division":"RefSeq","geneid":"7122","gi":"","length":"1699","nt_position":[],"snippet":"sapiens claudin 5 (CLDN5), transcript variant 2, mRNA. ACCESSION NM_003277 VERSION NM_003277.4 KEYWORDS RefSeq. SOURCE Homo sapiens (human) ORGANISM Homo sapiens Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. REFERENCE COMMENT REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DB023636.1 and AK092561.1. On Jun 2, 2019 this sequence version replaced NM_003277.3. Summary: This gene encodes a member of the claudin family. Claudins are...","source":"Homo sapiens (human)","symbol":"CLDN5","synonym":"AWAL; BEC1; CPETRL1; TMDVCF; TMVCF","version":"NM_003277.4"},{"aa_position":[],"accession":"NM_012129","definition":"Homo sapiens claudin 12 (CLDN12), transcript variant 3, mRNA.","division":"RefSeq","geneid":"9069","gi":"","length":"3490","nt_position":[],"snippet":"Homo sapiens claudin 12 (CLDN12), transcript variant 3, mRNA. ACCESSION NM_012129 VERSION NM_012129.5 KEYWORDS RefSeq. SOURCE Homo sapiens (human) ORGANISM Homo sapiens Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. REFERENCE COMMENT REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC006153.2. On May 31, 2019 this sequence version replaced NM_012129.4. Summary: This gene encodes a member of the claudin family. Claudins are integral...","source":"Homo sapiens (human)","symbol":"CLDN12","synonym":"","version":"NM_012129.5"},{"aa_position":[],"accession":"NM_001185073","definition":"Homo sapiens claudin 12 (CLDN12), transcript variant 2, mRNA.","division":"RefSeq","geneid":"9069","gi":"","length":"3494","nt_position":[],"snippet":"sapiens claudin 12 (CLDN12), transcript variant 2, mRNA. ACCESSION NM_001185073 VERSION NM_001185073.3 KEYWORDS RefSeq. SOURCE Homo sapiens (human) ORGANISM Homo sapiens Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. REFERENCE COMMENT REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC006153.2. On May 31, 2019 this sequence version replaced NM_001185073.2. Summary: This gene encodes a member of the claudin family. Claudins are integral...","source":"Homo sapiens (human)","symbol":"CLDN12","synonym":"","version":"NM_001185073.3"},{"aa_position":[],"accession":"NM_016369","definition":"Homo sapiens claudin 18 (CLDN18), transcript variant 1, mRNA.","division":"RefSeq","geneid":"51208","gi":"","length":"3355","nt_position":[],"snippet":"COMMENT VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AY358479.1, AK098474.1, BM785703.1 and AY102073.1. On Nov 23, 2018 this sequence version replaced NM_016369.3. Summary: This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining...","source":"Homo sapiens (human)","symbol":"CLDN18","synonym":"SFTA5; SFTPJ","version":"NM_016369.4"},{"aa_position":[],"accession":"NM_001185072","definition":"Homo sapiens claudin 12 (CLDN12), transcript variant 1, mRNA.","division":"RefSeq","geneid":"9069","gi":"","length":"3533","nt_position":[],"snippet":"iens claudin 12 (CLDN12), transcript variant 1, mRNA. ACCESSION NM_001185072 VERSION NM_001185072.3 KEYWORDS RefSeq; MANE Select. SOURCE Homo sapiens (human) ORGANISM Homo sapiens Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. REFERENCE COMMENT REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC006153.2. On Nov 24, 2018 this sequence version replaced NM_001185072.2. Summary: This gene encodes a member of the claudin family. Claudins...","source":"Homo sapiens (human)","symbol":"CLDN12","synonym":"","version":"NM_001185072.3"},{"aa_position":[],"accession":"NM_001363067","definition":"Homo sapiens claudin 5 (CLDN5), transcript variant 3, mRNA.","division":"RefSeq","geneid":"7122","gi":"","length":"1800","nt_position":[],"snippet":"piens claudin 5 (CLDN5), transcript variant 3, mRNA. ACCESSION NM_001363067 XM_017028929 VERSION NM_001363067.2 KEYWORDS RefSeq. SOURCE Homo sapiens (human) ORGANISM Homo sapiens Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. REFERENCE COMMENT REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC000082.4. On Jun 2, 2019 this sequence version replaced NM_001363067.1. Summary: This gene encodes a member of the claudin family. Claudins are...","source":"Homo sapiens (human)","symbol":"CLDN5","synonym":"AWAL; BEC1; CPETRL1; TMDVCF; TMVCF","version":"NM_001363067.2"},{"aa_position":[],"accession":"NM_001111319","definition":"Homo sapiens claudin 22 (CLDN22), mRNA.","division":"RefSeq","geneid":"53842","gi":"","length":"2177","nt_position":[],"snippet":"was derived from AC093844.3. On Jan 10, 2020 this sequence version replaced NM_001111319.2. Summary: This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent...function of claudins JOURNAL Biochim Biophys Acta 1778 (3), 631-645 (2008) PUBMED 18036336 REMARK Review article REFERENCE 4 (bases 1 to 2177) AUTHORS Katoh,M. and Katoh,M. TITLE CLDN23 gene, frequently down-regulated in intestinal-type gastric cancer, is a novel member of CLAUDIN gene family...","source":"Homo sapiens (human)","symbol":"CLDN22","synonym":"CLDN21","version":"NM_001111319.3"},{"aa_position":[],"accession":"NM_021101","definition":"Homo sapiens claudin 1 (CLDN1), mRNA.","division":"RefSeq","geneid":"9076","gi":"","length":"3446","nt_position":[],"snippet":"associated epithelial membrane protein 1\" /codon_start=1 /product=\"claudin-1\" /protein_id=\"NP_066924.1\" /db_xref=\"CCDS:CCDS3295.1\" /db_xref=\"GeneID:9076\" /db_xref=\"HGNC:HGNC:2032\" /db_xref=\"MIM:603718\" /translation=\"MANAGLQLLGFILAFLGWIGAIVSTALPQWRIYSYAGDNIVTAQAMYEGLWMSCVSQSTGQIQCKVFDSLLNLSSTLQATRALMVVGILLGVIAIFVATVGMKCMKCLEDDEVQKMRMAVIGGAIFLLAGLAILVATAWYGNRIVQEFYDPMTPVNARYEFGQALFTGWAAASLCLLGGALLCCSCPRKTTSYPTPRPYPKPAPSSGKDYV\" misc_feature 253..759 /gene=\"CLDN1\" /gene_synonym=\"CLD1; ILVASC; SEMP1\" /note=\"PMP-22/EMP/MP20/Claudin family; Region: PMP22_Claudin; pfam00822\" /db_xref=\"CDD:395662\" misc...","source":"Homo sapiens (human)","symbol":"CLDN1","synonym":"CLD1; ILVASC; SEMP1","version":"NM_021101.5"},{"aa_position":[],"accession":"NM_148960","definition":"Homo sapiens claudin 19 (CLDN19), transcript variant 1, mRNA.","division":"RefSeq","geneid":"149461","gi":"","length":"2841","nt_position":[],"snippet":"is encoded by transcript variant 1\" /codon_start=1 /product=\"claudin-19 isoform a\" /protein_id=\"NP_683763.2\" /db_xref=\"CCDS:CCDS471.1\" /db_xref=\"GeneID:149461\" /db_xref=\"HGNC:HGNC:2040\" /db_xref=\"MIM:610036\" /translation=\"MANSGLQLLGYFLALGGWVGIIASTALPQWKQSSYAGDAIITAVGLYEGLWMSCASQSTGQVQCKLYDSLLALDGHIQSARALMVVAVLLGFVAMVLSVVGMKCTRVGDSNPIAKGRVAIAGGALFILAGLCTLTAVSWYATLVTQEFFNPSTPVNARYEFGPALFVGWASAGLAVLGGSFLCCTCPEPERPNSSPQPYRPGPSAAAREPVVKLPASAKGPLGV\" misc_feature 183..719 /gene=\"CLDN19\" /gene_synonym=\"HOMG5\" /note=\"PMP-22/EMP/MP20/Claudin family; Region: PMP22_Claudin; cl21598\" /db_xref=\"CDD:473919\"...","source":"Homo sapiens (human)","symbol":"CLDN19","synonym":"HOMG5","version":"NM_148960.3"},{"aa_position":[],"accession":"NM_006580","definition":"Homo sapiens claudin 16 (CLDN16), transcript variant 1, mRNA.","division":"RefSeq","geneid":"10686","gi":"","length":"2977","nt_position":[],"snippet":"deleterious mRNA alterations JOURNAL BMC Med Genet 20 (1), 6 (2019) PUBMED 30621608 REMARK GeneRIF: Mutations in CLDN16 that encodes claudin-16, a tight-junction protein involved in paracellular reabsorption of magnesium and calcium in the renal tubule. Publication Status: Online-Only REFERENCE 5 (bases 1 to 2977) AUTHORS Arcidiacono,T., Simonini,M., Lanzani,C., Citterio,L., Salvi,E., Barlassina,C., Spotti,D., Cusi,D., Manunta,P. and Vezzoli,G. TITLE Claudin-14 Gene Polymorphisms and Urine Calcium Excretion JOURNAL Clin J Am Soc Nephrol 13 (10), 1542-1549 (2018) PUBMED 30232134 REMARK GeneRIF...","source":"Homo sapiens (human)","symbol":"CLDN16","synonym":"HOMG3; PCLN1","version":"NM_006580.4"},{"aa_position":[],"accession":"NM_001185056","definition":"Homo sapiens claudin 11 (CLDN11), transcript variant 2, mRNA.","division":"RefSeq","geneid":"5010","gi":"","length":"2445","nt_position":[],"snippet":"ens claudin 11 (CLDN11), transcript variant 2, mRNA. ACCESSION NM_001185056 VERSION NM_001185056.2 KEYWORDS RefSeq. SOURCE Homo sapiens (human) ORGANISM Homo sapiens Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. REFERENCE COMMENT REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC008041.5 and DA258090.1. On Jun 2, 2019 this sequence version replaced NM_001185056.1. Summary: This gene encodes a member of the claudin family. Claudins...","source":"Homo sapiens (human)","symbol":"CLDN11","synonym":"HLD22; OSP; OTM","version":"NM_001185056.2"},{"aa_position":[],"accession":"NM_001378493","definition":"Homo sapiens claudin 16 (CLDN16), transcript variant 3, mRNA.","division":"RefSeq","geneid":"10686","gi":"","length":"3319","nt_position":[],"snippet":"deleterious mRNA alterations JOURNAL BMC Med Genet 20 (1), 6 (2019) PUBMED 30621608 REMARK GeneRIF: Mutations in CLDN16 that encodes claudin-16, a tight-junction protein involved in paracellular reabsorption of magnesium and calcium in the renal tubule. Publication Status: Online-Only REFERENCE 5 (bases 1 to 3319) AUTHORS Arcidiacono,T., Simonini,M., Lanzani,C., Citterio,L., Salvi,E., Barlassina,C., Spotti,D., Cusi,D., Manunta,P. and Vezzoli,G. TITLE Claudin-14 Gene Polymorphisms and Urine Calcium Excretion JOURNAL Clin J Am Soc Nephrol 13 (10), 1542-1549 (2018) PUBMED 30232134 REMARK GeneRIF...","source":"Homo sapiens (human)","symbol":"CLDN16","synonym":"HOMG3; PCLN1","version":"NM_001378493.1"},{"aa_position":[],"accession":"NM_005602","definition":"Homo sapiens claudin 11 (CLDN11), transcript variant 1, mRNA.","division":"RefSeq","geneid":"5010","gi":"","length":"2758","nt_position":[],"snippet":"Hominidae; Homo. REFERENCE COMMENT REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC328248.1, BC013577.1 and AC008041.5. On Jun 2, 2019 this sequence version replaced NM_005602.5. Summary: This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining...","source":"Homo sapiens (human)","symbol":"CLDN11","synonym":"HLD22; OSP; OTM","version":"NM_005602.6"},{"aa_position":[],"accession":"XM_047440736","definition":"PREDICTED: Homo sapiens claudin 14 (CLDN14), transcript variant X2, mRNA.","division":"RefSeq","geneid":"23562","gi":"","length":"2277","nt_position":[],"snippet":"gene=\"CLDN14\" /gene_synonym=\"DFNB29\" /codon_start=1 /product=\"claudin-14 isoform X1\" /protein_id=\"XP_047296692.1\" /db_xref=\"GeneID:23562\" /db_xref=\"HGNC:HGNC:2035\" /db_xref=\"MIM:605608\" /translation=\"MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTGIYQCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKGTPAKTTFAILGGTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGTLLCLSCQDEAPYRPYQAPPRATTTTANTAPAYQPPAAYKDNRAPSVTSATHSGYRLNDYV\" misc_feature 1269..1745 /gene=\"CLDN14\" /gene_synonym=\"DFNB29\" /note=\"PMP-22/EMP/MP20/Claudin family; Region: PMP22_Claudin; cl21598\" /db_xref=\"CDD:473919\"...","source":"Homo sapiens (human)","symbol":"CLDN14","synonym":"DFNB29","version":"XM_047440736.1"},{"aa_position":[],"accession":"NM_001378492","definition":"Homo sapiens claudin 16 (CLDN16), transcript variant 2, mRNA.","division":"RefSeq","geneid":"10686","gi":"","length":"3486","nt_position":[],"snippet":"deleterious mRNA alterations JOURNAL BMC Med Genet 20 (1), 6 (2019) PUBMED 30621608 REMARK GeneRIF: Mutations in CLDN16 that encodes claudin-16, a tight-junction protein involved in paracellular reabsorption of magnesium and calcium in the renal tubule. Publication Status: Online-Only REFERENCE 5 (bases 1 to 3486) AUTHORS Arcidiacono,T., Simonini,M., Lanzani,C., Citterio,L., Salvi,E., Barlassina,C., Spotti,D., Cusi,D., Manunta,P. and Vezzoli,G. TITLE Claudin-14 Gene Polymorphisms and Urine Calcium Excretion JOURNAL Clin J Am Soc Nephrol 13 (10), 1542-1549 (2018) PUBMED 30232134 REMARK GeneRIF...","source":"Homo sapiens (human)","symbol":"CLDN16","synonym":"HOMG3; PCLN1","version":"NM_001378492.1"},{"aa_position":[],"accession":"NM_001040200","definition":"Homo sapiens claudin domain containing 1 (CLDND1), transcript variant 7, mRNA.","division":"RefSeq","geneid":"56650","gi":"","length":"1700","nt_position":[],"snippet":"protein; claudin domain-containing protein 1; membrane protein GENX-3745; claudin-25\" /codon_start=1 /product=\"claudin domain-containing protein 1 isoform d\" /protein_id=\"NP_001035290.1\" /db_xref=\"CCDS:CCDS43116.1\" /db_xref=\"GeneID:56650\" /db_xref=\"HGNC:HGNC:1322\" /db_xref=\"MIM:619677\" /translation=\"MGESFDVVTKCVSFTLTEQFMEKFVDPGNHNSGIDLLRTYLWRCQFLLPFVSLGLMCFGALIGLCACICRSLYPTIATGILHLLAGLCTLGSVSCYVAGIELLHQKLELPDNVSGEFGWSFCLACVSAPLQFMASALFIWAAHTNRKEYTLMKAYRVA\" misc_feature <177..464 /gene=\"CLDND1\" /gene_synonym=\"C3orf4; CLDN-25; GENX-3745; Z38\" /note=\"PMP-22/EMP/MP20/Claudin family; Region: PMP22_...","source":"Homo sapiens (human)","symbol":"CLDND1","synonym":"C3orf4; CLDN-25; GENX-3745; Z38","version":"NM_001040200.2"},{"aa_position":[],"accession":"NM_001290098","definition":"Homo sapiens transmembrane protein 114 (TMEM114), transcript variant 4, mRNA.","division":"RefSeq","geneid":"283953","gi":"","length":"571","nt_position":[],"snippet":"note=\"isoform d is encoded by transcript variant 4; claudin-26\" /codon_start=1 /product=\"transmembrane protein 114 isoform d\" /protein_id=\"NP_001277027.1\" /db_xref=\"GeneID:283953\" /db_xref=\"HGNC:HGNC:33227\" /db_xref=\"MIM:611579\" /translation=\"MRVHLGGLAGAAALTGALSFVLLAAAIGTDFWYIIDTERLERTGPGAQDLLGSINRSQPEPLSSHSGLWRTCRVQSPCTPLMNPFRLENVTVSESSRQLLTAF\" misc_feature 19..81 /gene=\"TMEM114\" /note=\"propagated from UniProtKB/Swiss-Prot (B3SHH9.2); transmembrane region\" misc_feature 55..>261 /gene=\"TMEM114\" /note=\"PMP-22/EMP/MP20/Claudin family; Region: PMP22_Claudin; cl21598\" /db_xref=\"CDD:473919\" misc_...","source":"Homo sapiens (human)","symbol":"TMEM114","synonym":"","version":"NM_001290098.1"},{"aa_position":[],"accession":"NM_001130861","definition":"Homo sapiens claudin 5 (CLDN5), transcript variant 1, mRNA.","division":"RefSeq","geneid":"7122","gi":"","length":"2332","nt_position":[],"snippet":"DEFINITION Homo sapiens claudin 5 (CLDN5), transcript variant 1, mRNA. ACCESSION NM_001130861 VERSION NM_001130861.1 KEYWORDS RefSeq. SOURCE Homo sapiens (human) ORGANISM Homo sapiens Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. REFERENCE COMMENT REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK092561.1, AK124019.1 and BU688528.1. Summary: This gene encodes a member of the claudin family. Claudins are integral membrane proteins and...","source":"Homo sapiens (human)","symbol":"CLDN5","synonym":"AWAL; BEC1; CPETRL1; TMDVCF; TMVCF","version":"NM_001130861.1"},{"aa_position":[],"accession":"NM_194284","definition":"Homo sapiens claudin 23 (CLDN23), mRNA.","division":"RefSeq","geneid":"137075","gi":"","length":"2160","nt_position":[],"snippet":"BC125149.1 and BC016047.1. On May 17, 2019 this sequence version replaced NM_194284.2. Summary: This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes...AUTHORS Katoh,M. and Katoh,M. TITLE CLDN23 gene, frequently down-regulated in intestinal-type gastric cancer, is a novel member of CLAUDIN gene family JOURNAL Int J Mol Med 11 (6), 683-689 (2003) PUBMED 12736707 REMARK GeneRIF: characterization of CLDN23 gene, a candidate tumor suppressor...","source":"Homo sapiens (human)","symbol":"CLDN23","synonym":"CLDNL; hCG1646163","version":"NM_194284.3"},{"aa_position":[],"accession":"NM_001185117","definition":"Homo sapiens claudin 19 (CLDN19), transcript variant 3, mRNA.","division":"RefSeq","geneid":"149461","gi":"","length":"3499","nt_position":[],"snippet":"is encoded by transcript variant 3\" /codon_start=1 /product=\"claudin-19 isoform c\" /protein_id=\"NP_001172046.1\" /db_xref=\"CCDS:CCDS53306.1\" /db_xref=\"GeneID:149461\" /db_xref=\"HGNC:HGNC:2040\" /db_xref=\"MIM:610036\" /translation=\"MANSGLQLLGYFLALGGWVGIIASTALPQWKQSSYAGDAIITAVGLYEGLWMSCASQSTGQVQCKLYDSLLALDGHIQSARALMVVAVLLGFVAMVLSVVGMKCTRVGDSNPIAKGRVAIAGGALFILAGMNLAQPCSWAGPQLAWPCWAAPSSAAHARSQRDPTAAHSPIGLDPLLLPESTSELRLPWPAPHPVAPLPSIQPASQHPGQGHWGIGWA\" misc_feature 183..>590 /gene=\"CLDN19\" /gene_synonym=\"HOMG5\" /note=\"PMP-22/EMP/MP20/Claudin family; Region: PMP22_Claudin; cl21598\" /db_xref=\"CDD:473919\"...","source":"Homo sapiens (human)","symbol":"CLDN19","synonym":"HOMG5","version":"NM_001185117.2"},{"aa_position":[],"accession":"NM_001040183","definition":"Homo sapiens claudin domain containing 1 (CLDND1), transcript variant 3, mRNA.","division":"RefSeq","geneid":"56650","gi":"","length":"2005","nt_position":[],"snippet":"and Inoue,A. TITLE Claudin domain containing 1 contributing to endothelial cell adhesion decreases in presence of cerebellar hemorrhage JOURNAL J Neurosci Res 95 (10), 2051-2058 (2017) PUBMED 28244141 REMARK GeneRIF: suggest that the transient decrease of CLDND1 after cerebellar hemorrhage is responsible for low-molecular-weight selective vascular hyperpermeability REFERENCE 6 (bases 1 to 2005) AUTHORS Matsuoka,H., Shima,A., Uda,A., Ezaki,H. and Michihara,A. TITLE The retinoic acid receptor-related orphan receptor alpha positively regulates tight junction protein claudin domain-containing 1...","source":"Homo sapiens (human)","symbol":"CLDND1","synonym":"C3orf4; CLDN-25; GENX-3745; Z38","version":"NM_001040183.2"},{"aa_position":[],"accession":"NM_001040181","definition":"Homo sapiens claudin domain containing 1 (CLDND1), transcript variant 1, mRNA.","division":"RefSeq","geneid":"56650","gi":"","length":"2010","nt_position":[],"snippet":"and Inoue,A. TITLE Claudin domain containing 1 contributing to endothelial cell adhesion decreases in presence of cerebellar hemorrhage JOURNAL J Neurosci Res 95 (10), 2051-2058 (2017) PUBMED 28244141 REMARK GeneRIF: suggest that the transient decrease of CLDND1 after cerebellar hemorrhage is responsible for low-molecular-weight selective vascular hyperpermeability REFERENCE 6 (bases 1 to 2010) AUTHORS Matsuoka,H., Shima,A., Uda,A., Ezaki,H. and Michihara,A. TITLE The retinoic acid receptor-related orphan receptor alpha positively regulates tight junction protein claudin domain-containing 1...","source":"Homo sapiens (human)","symbol":"CLDND1","synonym":"C3orf4; CLDN-25; GENX-3745; Z38","version":"NM_001040181.2"},{"aa_position":[],"accession":"NM_001123395","definition":"Homo sapiens claudin 19 (CLDN19), transcript variant 2, mRNA.","division":"RefSeq","geneid":"149461","gi":"","length":"3584","nt_position":[],"snippet":"b is encoded by transcript variant 2\" /codon_start=1 /product=\"claudin-19 isoform b\" /protein_id=\"NP_001116867.1\" /db_xref=\"CCDS:CCDS44125.1\" /db_xref=\"GeneID:149461\" /db_xref=\"HGNC:HGNC:2040\" /db_xref=\"MIM:610036\" /translation=\"MANSGLQLLGYFLALGGWVGIIASTALPQWKQSSYAGDAIITAVGLYEGLWMSCASQSTGQVQCKLYDSLLALDGHIQSARALMVVAVLLGFVAMVLSVVGMKCTRVGDSNPIAKGRVAIAGGALFILAGLCTLTAVSWYATLVTQEFFNPSTPVNARYEFGPALFVGWASAGLAVLGGSFLCCTCPEPERPNSSPQPYRPGPSAAAREYV\" misc_feature 183..719 /gene=\"CLDN19\" /gene_synonym=\"HOMG5\" /note=\"PMP-22/EMP/MP20/Claudin family; Region: PMP22_Claudin; cl21598\" /db_xref=\"CDD:473919\" misc_...","source":"Homo sapiens (human)","symbol":"CLDN19","synonym":"HOMG5","version":"NM_001123395.2"},{"aa_position":[],"accession":"NM_001040182","definition":"Homo sapiens claudin domain containing 1 (CLDND1), transcript variant 4, mRNA.","division":"RefSeq","geneid":"56650","gi":"","length":"2054","nt_position":[],"snippet":"and Inoue,A. TITLE Claudin domain containing 1 contributing to endothelial cell adhesion decreases in presence of cerebellar hemorrhage JOURNAL J Neurosci Res 95 (10), 2051-2058 (2017) PUBMED 28244141 REMARK GeneRIF: suggest that the transient decrease of CLDND1 after cerebellar hemorrhage is responsible for low-molecular-weight selective vascular hyperpermeability REFERENCE 6 (bases 1 to 2054) AUTHORS Matsuoka,H., Shima,A., Uda,A., Ezaki,H. and Michihara,A. TITLE The retinoic acid receptor-related orphan receptor alpha positively regulates tight junction protein claudin domain-containing 1...","source":"Homo sapiens (human)","symbol":"CLDND1","synonym":"C3orf4; CLDN-25; GENX-3745; Z38","version":"NM_001040182.2"},{"aa_position":[],"accession":"NM_019895","definition":"Homo sapiens claudin domain containing 1 (CLDND1), transcript variant 2, mRNA.","division":"RefSeq","geneid":"56650","gi":"","length":"2061","nt_position":[],"snippet":"and Inoue,A. TITLE Claudin domain containing 1 contributing to endothelial cell adhesion decreases in presence of cerebellar hemorrhage JOURNAL J Neurosci Res 95 (10), 2051-2058 (2017) PUBMED 28244141 REMARK GeneRIF: suggest that the transient decrease of CLDND1 after cerebellar hemorrhage is responsible for low-molecular-weight selective vascular hyperpermeability REFERENCE 6 (bases 1 to 2061) AUTHORS Matsuoka,H., Shima,A., Uda,A., Ezaki,H. and Michihara,A. TITLE The retinoic acid receptor-related orphan receptor alpha positively regulates tight junction protein claudin domain-containing 1...","source":"Homo sapiens (human)","symbol":"CLDND1","synonym":"C3orf4; CLDN-25; GENX-3745; Z38","version":"NM_019895.3"},{"aa_position":[],"accession":"NR_031681","definition":"Homo sapiens microRNA 1275 (MIR1275), microRNA.","division":"RefSeq","geneid":"100302123","gi":"","length":"80","nt_position":[],"snippet":"Genome-wide association analysis of age-at-onset in Alzheimer's disease JOURNAL Mol Psychiatry 17 (12), 1340-1346 (2012) PUBMED 22005931 REFERENCE 7 (bases 1 to 80) AUTHORS Katsushima K, Shinjo K, Natsume A, Ohka F, Fujii M, Osada H, Sekido Y and Kondo Y. TITLE Contribution of microRNA-1275 to Claudin11 protein suppression via a polycomb-mediated silencing mechanism in human glioma stem-like cells JOURNAL J Biol Chem 287 (33), 27396-27406 (2012) PUBMED 22736761 REMARK GeneRIF: Treatment with 3-deazaneplanocin A, an inhibitor of H3K27 methyltransferase, attenuated CLDN11 induction by serum...","source":"Homo sapiens (human)","symbol":"MIR1275","synonym":"hsa-mir-1275; mir-1275; MIRN1275","version":"NR_031681.1"},{"aa_position":[],"accession":"XM_047447333","definition":"PREDICTED: Homo sapiens claudin 16 (CLDN16), transcript variant X1, mRNA.","division":"RefSeq","geneid":"10686","gi":"","length":"3083","nt_position":[],"snippet":"CLDN16\" /gene_synonym=\"HOMG3; PCLN1\" /codon_start=1 /product=\"claudin-16 isoform X1\" /protein_id=\"XP_047303289.1\" /db_xref=\"GeneID:10686\" /db_xref=\"HGNC:HGNC:2037\" /db_xref=\"MIM:603959\" /translation=\"MRDLLQYIACFFAFFSAGFLIVATWTDCWMVNADDSLEVSTKCRGLWWECVTNAFDGIRTCDEYDSILAEHPLKLVVTRALMITADILAGFGFLTLLLGLDCVKFLPDEPYIKVRICFVAGATLLIAGTPGIIGSVWYAVDVYVERSTLVLHNIFLGIQYKFGWSCWLGMAGSLGCFLAGAVLTCCLYLFKDVGPERNYPYSLRKAYSAAGVSMAKSYSAPRTETAKMYAVDTRV\" misc_feature 304..822 /gene=\"CLDN16\" /gene_synonym=\"HOMG3; PCLN1\" /note=\"PMP-22/EMP/MP20/Claudin family; Region: PMP22_Claudin; cl21598\" /db_xref=\"CDD:473919\"...","source":"Homo sapiens (human)","symbol":"CLDN16","synonym":"HOMG3; PCLN1","version":"XM_047447333.1"},{"aa_position":[],"accession":"NM_001040199","definition":"Homo sapiens claudin domain containing 1 (CLDND1), transcript variant 6, mRNA.","division":"RefSeq","geneid":"56650","gi":"","length":"2317","nt_position":[],"snippet":"and Inoue,A. TITLE Claudin domain containing 1 contributing to endothelial cell adhesion decreases in presence of cerebellar hemorrhage JOURNAL J Neurosci Res 95 (10), 2051-2058 (2017) PUBMED 28244141 REMARK GeneRIF: suggest that the transient decrease of CLDND1 after cerebellar hemorrhage is responsible for low-molecular-weight selective vascular hyperpermeability REFERENCE 6 (bases 1 to 2317) AUTHORS Matsuoka,H., Shima,A., Uda,A., Ezaki,H. and Michihara,A. TITLE The retinoic acid receptor-related orphan receptor alpha positively regulates tight junction protein claudin domain-containing 1...","source":"Homo sapiens (human)","symbol":"CLDND1","synonym":"C3orf4; CLDN-25; GENX-3745; Z38","version":"NM_001040199.2"},{"aa_position":[],"accession":"XM_047440735","definition":"PREDICTED: Homo sapiens claudin 14 (CLDN14), transcript variant X1, mRNA.","division":"RefSeq","geneid":"23562","gi":"","length":"3905","nt_position":[],"snippet":"gene=\"CLDN14\" /gene_synonym=\"DFNB29\" /codon_start=1 /product=\"claudin-14 isoform X1\" /protein_id=\"XP_047296691.1\" /db_xref=\"GeneID:23562\" /db_xref=\"HGNC:HGNC:2035\" /db_xref=\"MIM:605608\" /translation=\"MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTGIYQCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKGTPAKTTFAILGGTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGTLLCLSCQDEAPYRPYQAPPRATTTTANTAPAYQPPAAYKDNRAPSVTSATHSGYRLNDYV\" misc_feature 2897..3373 /gene=\"CLDN14\" /gene_synonym=\"DFNB29\" /note=\"PMP-22/EMP/MP20/Claudin family; Region: PMP22_Claudin; cl21598\" /db_xref=\"CDD:473919\"...","source":"Homo sapiens (human)","symbol":"CLDN14","synonym":"DFNB29","version":"XM_047440735.1"},{"aa_position":[],"accession":"NR_031638","definition":"Homo sapiens microRNA 1303 (MIR1303), microRNA.","division":"RefSeq","geneid":"100302284","gi":"","length":"86","nt_position":[],"snippet":"and miR-1303. Moreover, the levels of the five miRNAs were higher in patients with complications than in those without complications. Publication Status: Online-Only REFERENCE 7 (bases 1 to 86) AUTHORS Zhang,S.J., Feng,J.F., Wang,L., Guo,W., Du,Y.W., Ming,L. and Zhao,G.Q. TITLE miR-1303 targets claudin-18 gene to modulate proliferation and invasion of gastric cancer cells JOURNAL Dig Dis Sci 59 (8), 1754-1763 (2014) PUBMED 24647998 REMARK GeneRIF: Downregulation of miR-1303 can inhibit proliferation, migration and invasion of gastric cancer cells by targeting CLDN18. REFERENCE 8...","source":"Homo sapiens (human)","symbol":"MIR1303","synonym":"hsa-mir-1303; MIRN1303","version":"NR_031638.1"},{"aa_position":[],"accession":"XM_017003376","definition":"PREDICTED: Homo sapiens transmembrane protein 182 (TMEM182), transcript variant X4, mRNA.","division":"RefSeq","geneid":"130827","gi":"","length":"843","nt_position":[],"snippet":"protein 182 isoform X3\" /protein_id=\"XP_016858865.1\" /db_xref=\"GeneID:130827\" /db_xref=\"HGNC:HGNC:26391\" /translation=\"MRGEHNSTSYDSAVIYRGFWAVLMLLGVVAVVIASFLIICAAPFASHFLYKAGGGSYIAADGISSLCYSSLSKSLLSQPLRETSSAINDISLLQALMPLLGWTSHWTCITVGLY\" misc_feature 415 /gene=\"TMEM182\" /note=\"PMP-22/EMP/MP20/Claudin family; Region: PMP22_Claudin; cl21598\" /db_xref=\"CDD:473919\" variation 237..238 /gene=\"TMEM182\" /replace=\"\" /replace=\"tg\" /db_xref=\"dbSNP:2466715676\" variation 237 /gene=\"TMEM182\" /replace=\"c\" /replace=\"g\" /replace=\"t\" /db_xref=\"dbSNP:2466715660\" variation 238 /gene=\"TMEM182\" /replace=\"a\" /replace=\"...","source":"Homo sapiens (human)","symbol":"TMEM182","synonym":"","version":"XM_017003376.2"},{"aa_position":[],"accession":"NM_001382303","definition":"Homo sapiens ubiquitin specific peptidase 40 (USP40), transcript variant 11, mRNA.","division":"RefSeq","geneid":"55230","gi":"","length":"676","nt_position":[],"snippet":"positive feedback loop. REFERENCE 2 (bases 1 to 676) AUTHORS Wu,Q., Qiu,Y., Guo,J., Yuan,Z., Yang,Y., Zhu,Q., Zhang,Z., Guo,J., Wu,Y., Zhang,J., Huang,D., Tu,K. and Hu,X. TITLE USP40 promotes hepatocellular carcinoma cell proliferation, migration and stemness by deubiquitinating and stabilizing Claudin1 JOURNAL Biol Direct 19 (1), 13 (2024) PUBMED 38308285 REMARK GeneRIF: USP40 promotes hepatocellular carcinoma cell proliferation, migration and stemness by deubiquitinating and stabilizing Claudin1. Publication Status: Online-Only REFERENCE 3 (bases 1 to 676) AUTHORS Miao,J., Li,L., Shaheen,N...","source":"Homo sapiens (human)","symbol":"USP40","synonym":"","version":"NM_001382303.1"},{"aa_position":[],"accession":"XM_006723228","definition":"PREDICTED: Homo sapiens natural killer cell granule protein 7 (NKG7), transcript variant X2, mRNA.","division":"RefSeq","geneid":"4818","gi":"","length":"627","nt_position":[],"snippet":"GeneID:4818\" /db_xref=\"HGNC:HGNC:7830\" /db_xref=\"MIM:606008\" /translation=\"MELCRSLALLGGSLGLMFCLIALSTDFWFEAVGPTHSAHSGLWPTGHGDIISAISMVVAMAVYTSERWDQPPHPQIQTFFSWSFYLGWVSAILLLCTGALSLGAHCGGPRPGYETL\" misc_feature <267..419 /gene=\"NKG7\" /gene_synonym=\"GIG1; GMP-17; p15-TIA-1\" /note=\"PMP-22/EMP/MP20/Claudin family; Region: PMP22_Claudin; cl21598\" /db_xref=\"CDD:473919\" variation 120 /gene=\"NKG7\" /gene_synonym=\"GIG1; GMP-17; p15-TIA-1\" /replace=\"a\" /replace=\"c\" /db_xref=\"dbSNP:2514190625\" variation 121 /gene=\"NKG7\" /gene_synonym=\"GIG1; GMP-17; p15-TIA-1\" /replace=\"g\" /replace=\"t\" /db_xref=\"dbSNP...","source":"Homo sapiens (human)","symbol":"NKG7","synonym":"GIG1; GMP-17; p15-TIA-1","version":"XM_006723228.4"},{"aa_position":[],"accession":"XM_011526605","definition":"PREDICTED: Homo sapiens epithelial membrane protein 3 (MAM blood group) (EMP3), transcript variant X1, mRNA.","division":"RefSeq","geneid":"2014","gi":"","length":"712","nt_position":[],"snippet":"HGNC:HGNC:3335\" /db_xref=\"MIM:602335\" /translation=\"MSLLLLVVSALHILILILLFVATLDKSWWTLPGKESLNLWYDCTWNNDTKTWACSNVSENGWLKAVQVLMVLSLILCCLSFILFMFQLYTMRRGGLFYATGLCQLCTSVAVFTGALIYAIHAEEILEKHPRGGSFGYCFALAWVAFPLALVSGIIYIHLRKRE\" misc_feature 195..605 /gene=\"EMP3\" /gene_synonym=\"YMP\" /note=\"PMP-22/EMP/MP20/Claudin family; Region: PMP22_Claudin; cl21598\" /db_xref=\"CDD:473919\" variation 138 /gene=\"EMP3\" /gene_synonym=\"YMP\" /replace=\"a\" /replace=\"g\" /replace=\"t\" /db_xref=\"dbSNP:777112006\" variation 140 /gene=\"EMP3\" /gene_synonym=\"YMP\" /replace=\"c\" /replace=\"g\" /db_xref=\"dbSNP:146324824\" variation 141..146 /...","source":"Homo sapiens (human)","symbol":"EMP3","synonym":"YMP","version":"XM_011526605.4"},{"aa_position":[],"accession":"XM_024450806","definition":"PREDICTED: Homo sapiens peripheral myelin protein 22 (PMP22), transcript variant X2, mRNA.","division":"RefSeq","geneid":"5376","gi":"","length":"543","nt_position":[],"snippet":"HGNC:9118\" /db_xref=\"MIM:601097\" /translation=\"MSIIVLHVAVLVLLFVSTIVSQWIVGNGHATDLWQNCSTSSSGNVHHCFSSSPNEWLQSVQATMILSIIFSILSLFLFFCQLFTLTKGGRFYITGIFQILAESNSSQMCGYRD\" misc_feature 222..>476 /gene=\"PMP22\" /gene_synonym=\"CIDP; CMT1A; CMT1E; DSS; GAS-3; GAS3; HMSNIA; HNPP; Sp110\" /note=\"PMP-22/EMP/MP20/Claudin family; Region: PMP22_Claudin; cl21598\" /db_xref=\"CDD:473919\" variation 164 /gene=\"PMP22\" /gene_synonym=\"CIDP; CMT1A; CMT1E; DSS; GAS-3; GAS3; HMSNIA; HNPP; Sp110\" /replace=\"c\" /replace=\"t\" /db_xref=\"dbSNP:1474281036\" variation 165 /gene=\"PMP22\" /gene_synonym=\"CIDP; CMT1A; CMT1E; DSS; GAS-3;...","source":"Homo sapiens (human)","symbol":"PMP22","synonym":"CIDP; CMT1A; CMT1E; DSS; GAS-3; GAS3; HMSNIA; HNPP; Sp110","version":"XM_024450806.2"},{"aa_position":[],"accession":"NM_001290097","definition":"Homo sapiens transmembrane protein 114 (TMEM114), transcript variant 3, mRNA.","division":"RefSeq","geneid":"283953","gi":"","length":"1217","nt_position":[],"snippet":"CDS 516..944 /gene=\"TMEM114\" /note=\"isoform c is encoded by transcript variant 3; claudin-26\" /codon_start=1 /product=\"transmembrane protein 114 isoform c\" /protein_id=\"NP_001277026.1\" /db_xref=\"CCDS:CCDS76819.1\" /db_xref=\"GeneID:283953\" /db_xref=\"HGNC:HGNC:33227\" /db_xref=\"MIM:611579\" /translation=\"MNPFRLENVTVSESSRQLLTMHGTFVILLPLSLILMVFGGMTGFLSFLLQAYTGILFLFGAMVTLAGISVYIAYSAAAFREALCLLEEKALLDQVDISFGWSLALGWISFIAELLTGAAFLAAARELSLRRRQDQAI\" misc_feature <546..893 /gene=\"TMEM114\" /note=\"PMP-22/EMP/MP20/Claudin family; Region: PMP22_Claudin; cl21598\" /db_xref=\"CDD:473919\" variation 517 /gene=\"...","source":"Homo sapiens (human)","symbol":"TMEM114","synonym":"","version":"NM_001290097.2"},{"aa_position":[],"accession":"XM_006712287","definition":"PREDICTED: Homo sapiens transmembrane protein 182 (TMEM182), transcript variant X1, mRNA.","division":"RefSeq","geneid":"130827","gi":"","length":"1083","nt_position":[],"snippet":"translation=\"MRLNIAIFFGALFGALGVLLFLVAFGSDYWLLATEVGRCSGEKNIENVTFHHEGFFWRCWFNGIVEENDSNIWKFWYTNQPPSKNCTHAYLSPYPFMRGEHNSTSYDSAVIYRGFWAVLMLLGVVAVVIASFLIICAAPFASHFLYKAGGGSYIAADGISSLCYSSLSKSLLSQPLRETSSAINDISLLQALMPLLGWTSHWTCITVGLY\" misc_feature 230..>655 /gene=\"TMEM182\" /note=\"PMP-22/EMP/MP20/Claudin tight junction; Region: Claudin_2; pfam13903\" /db_xref=\"CDD:372799\" variation 190 /gene=\"TMEM182\" /replace=\"g\" /replace=\"t\" /db_xref=\"dbSNP:2466706475\" variation 192 /gene=\"TMEM182\" /replace=\"a\" /replace=\"g\" /db_xref=\"dbSNP:2466706482\" variation 194 /gene=\"TMEM182\" /replace=\"\" /replace=\"c\" /db_xref=\"...","source":"Homo sapiens (human)","symbol":"TMEM182","synonym":"","version":"XM_006712287.2"},{"aa_position":[],"accession":"XM_047430765","definition":"PREDICTED: Homo sapiens claudin 10 (CLDN10), transcript variant X1, mRNA.","division":"RefSeq","geneid":"9071","gi":"","length":"5543","nt_position":[],"snippet":"gene=\"CLDN10\" /gene_synonym=\"CPETRL3; HELIX; OSP-L; OSPL\" /codon_start=1 /product=\"claudin-10 isoform X1\" /protein_id=\"XP_047286721.1\" /db_xref=\"GeneID:9071\" /db_xref=\"HGNC:HGNC:2033\" /db_xref=\"MIM:617579\" /translation=\"MRKINKLWLLFMLEKGYIQACRGLMIAAVSLGFFGSIFALFGMKCTKVGGSDKAKAKIACLAGIVFILSGLCSMTGCSLYANKITTEFFDPLFVEQKYELGAALFIGWAGASLCIIGGVIFCFSISDNNKTPRYTYNGATSVMSSRTKYHGGEDFKTTNPSKQFDKNAYV\" misc_feature <3331..3648 /gene=\"CLDN10\" /gene_synonym=\"CPETRL3; HELIX; OSP-L; OSPL\" /note=\"PMP-22/EMP/MP20/Claudin family; Region: PMP22_Claudin; cl21598\" /db_xref=\"CDD:473919\" variation 3289 /gene=\"CLDN10\" /...","source":"Homo sapiens (human)","symbol":"CLDN10","synonym":"CPETRL3; HELIX; OSP-L; OSPL","version":"XM_047430765.1"},{"aa_position":[],"accession":"NM_001290095","definition":"Homo sapiens transmembrane protein 114 (TMEM114), transcript variant 2, mRNA.","division":"RefSeq","geneid":"283953","gi":"","length":"1480","nt_position":[],"snippet":"TMEM114\" /note=\"isoform b is encoded by transcript variant 2; claudin-26\" /codon_start=1 /product=\"transmembrane protein 114 isoform b\" /protein_id=\"NP_001277024.1\" /db_xref=\"CCDS:CCDS76820.1\" /db_xref=\"GeneID:283953\" /db_xref=\"HGNC:HGNC:33227\" /db_xref=\"MIM:611579\" /translation=\"MRVHLGGLAGAAALTGALSFVLLAAAIGTDFWYIIDTERLERTGPGAQDLLGSINRSQPEPLSSHSGLWRTCRVQSPCTPLMNPFRLENVTVSESSRQLLTMVTLAGISVYIAYSAAAFREALCLLEEKALLDQVDISFGWSLALGWISFIAELLTGAAFLAAARELSLRRRQDQAI\" misc_feature 728..1156 /gene=\"TMEM114\" /note=\"PMP-22/EMP/MP20/Claudin family; Region: PMP22_Claudin; cl21598\" /db_xref=\"CDD:473919\"...","source":"Homo sapiens (human)","symbol":"TMEM114","synonym":"","version":"NM_001290095.2"},{"aa_position":[],"accession":"NM_005601","definition":"Homo sapiens natural killer cell granule protein 7 (NKG7), transcript variant 1, mRNA.","division":"RefSeq","geneid":"4818","gi":"","length":"774","nt_position":[],"snippet":"misc_feature 144..206 /gene=\"NKG7\" /gene_synonym=\"GIG1; GMP-17; p15-TIA-1\" /note=\"propagated from UniProtKB/Swiss-Prot (Q16617.1); transmembrane region\" misc_feature 180..566 /gene=\"NKG7\" /gene_synonym=\"GIG1; GMP-17; p15-TIA-1\" /note=\"PMP-22/EMP/MP20/Claudin family; Region: PMP22_Claudin; cl21598\" /db_xref=\"CDD:473919\" misc_feature 300..362 /gene=\"NKG7\" /gene_synonym=\"GIG1; GMP-17; p15-TIA-1\" /note=\"propagated from UniProtKB/Swiss-Prot (Q16617.1); transmembrane region\" misc_feature 393..455 /gene=\"NKG7\" /gene_synonym=\"GIG1; GMP-17; p15-TIA-1\" /note=\"propagated from UniProtKB/Swiss-Prot...","source":"Homo sapiens (human)","symbol":"NKG7","synonym":"GIG1; GMP-17; p15-TIA-1","version":"NM_005601.4"},{"aa_position":[],"accession":"NM_001146336","definition":"Homo sapiens transmembrane protein 114 (TMEM114), transcript variant 1, mRNA.","division":"RefSeq","geneid":"283953","gi":"","length":"1618","nt_position":[],"snippet":"TMEM114\" /replace=\"a\" /replace=\"g\" /db_xref=\"dbSNP:2505945304\" CDS 674..1345 /gene=\"TMEM114\" /note=\"isoform a is encoded by transcript variant 1; claudin-26\" /codon_start=1 /product=\"transmembrane protein 114 isoform a\" /protein_id=\"NP_001139808.1\" /db_xref=\"CCDS:CCDS73825.1\" /db_xref=\"GeneID...note=\"propagated from UniProtKB/Swiss-Prot (B3SHH9.2); transmembrane region\" misc_feature 728..1294 /gene=\"TMEM114\" /note=\"PMP-22/EMP/MP20/Claudin family; Region: PMP22_Claudin; cl21598\" /db_xref=\"CDD:473919\" misc_feature 836..838 /gene=\"TMEM114\" /note=\"N-linked (GlcNAc...) asparagine. /evidence=ECO...","source":"Homo sapiens (human)","symbol":"TMEM114","synonym":"","version":"NM_001146336.2"},{"aa_position":[],"accession":"NM_001313905","definition":"Homo sapiens epithelial membrane protein 3 (MAM blood group) (EMP3), transcript variant 2, mRNA.","division":"RefSeq","geneid":"2014","gi":"","length":"645","nt_position":[],"snippet":"misc_feature 80..142 /gene=\"EMP3\" /gene_synonym=\"YMP\" /note=\"propagated from UniProtKB/Swiss-Prot (P54852.1); transmembrane region\" misc_feature 128..538 /gene=\"EMP3\" /gene_synonym=\"YMP\" /note=\"PMP-22/EMP/MP20/Claudin family; Region: PMP22_Claudin; cl21598\" /db_xref=\"CDD:473919\" misc_feature 209..211 /gene=\"EMP3\" /gene_synonym=\"YMP\" /note=\"N-linked (GlcNAc...) asparagine. /evidence=ECO:0000255; propagated from UniProtKB/Swiss-Prot (P54852.1); glycosylation site\" misc_feature 236..238 /gene=\"EMP3\" /gene_synonym=\"YMP\" /note=\"N-linked (GlcNAc...) asparagine. /evidence=ECO:0000255; propagated from...","source":"Homo sapiens (human)","symbol":"EMP3","synonym":"YMP","version":"NM_001313905.1"},{"aa_position":[],"accession":"XM_011515705","definition":"PREDICTED: Homo sapiens transmembrane protein 178B (TMEM178B), transcript variant X3, mRNA.","division":"RefSeq","geneid":"100507421","gi":"","length":"1799","nt_position":[],"snippet":"misc_feature 545..>901 /gene=\"TMEM178B\" /note=\"PMP-22/EMP/MP20/Claudin family; Region: PMP22_Claudin; cl21598\" /db_xref=\"CDD:473919\" variation 248 /gene=\"TMEM178B\" /replace=\"a\" /replace=\"c\" /db_xref=\"dbSNP:1794559263\" variation 250 /gene=\"TMEM178B\" /replace=\"a\" /replace=\"g\" /db_xref=\"dbSNP:1465631743\" variation 251 /gene=\"TMEM178B\" /replace=\"a\" /replace=\"g\" /db_xref=\"dbSNP:2535656954\" variation 255 /gene=\"TMEM178B\" /replace=\"a\" /replace=\"c\" /replace=\"t\" /db_xref=\"dbSNP:2535656961\" variation 256 /gene=\"TMEM178B\" /replace=\"c\" /replace=\"t\" /db_xref=\"dbSNP:1794559379\" variation 257 /gene=\"TMEM178B...","source":"Homo sapiens (human)","symbol":"TMEM178B","synonym":"","version":"XM_011515705.3"},{"aa_position":[],"accession":"XM_047435764","definition":"PREDICTED: Homo sapiens transmembrane protein 235 (TMEM235), transcript variant X6, mRNA.","division":"RefSeq","geneid":"283999","gi":"","length":"958","nt_position":[],"snippet":"misc_feature 299..>625 /gene=\"TMEM235\" /gene_synonym=\"ARGM1\" /note=\"PMP-22/EMP/MP20/Claudin family; Region: PMP22_Claudin; cl21598\" /db_xref=\"CDD:473919\" variation 218 /gene=\"TMEM235\" /gene_synonym=\"ARGM1\" /replace=\"a\" /replace=\"c\" /replace=\"g\" /db_xref=\"dbSNP:867349976\" variation 219 /gene=\"TMEM235\" /gene_synonym=\"ARGM1\" /replace=\"a\" /replace=\"t\" /db_xref=\"dbSNP:1025207372\" variation 220 /gene=\"TMEM235\" /gene_synonym=\"ARGM1\" /replace=\"a\" /replace=\"c\" /replace=\"g\" /db_xref=\"dbSNP:1312298646\" variation 221 /gene=\"TMEM235\" /gene_synonym=\"ARGM1\" /replace=\"a\" /replace=\"g\" /db_xref=\"dbSNP...","source":"Homo sapiens (human)","symbol":"TMEM235","synonym":"ARGM1","version":"XM_047435764.1"},{"aa_position":[],"accession":"XM_017003371","definition":"PREDICTED: Homo sapiens transmembrane protein 178A (TMEM178A), transcript variant X5, mRNA.","division":"RefSeq","geneid":"130733","gi":"","length":"1304","nt_position":[],"snippet":"id=\"XP_016858860.1\" /db_xref=\"GeneID:130733\" /db_xref=\"HGNC:HGNC:28517\" /translation=\"MAVAVLLCGCIVATVSFFWEESLTQHVAGLLFLMTGIFCTISLCTYAASISYDLNRLPKLIYSLPADVEHGYSWSIFCAWCSLGFIVAAGGLCIAYPFISRTKIAQLKSGRDSTV\" misc_feature <248..520 /gene=\"TMEM178A\" /gene_synonym=\"TMEM178\" /note=\"PMP-22/EMP/MP20/Claudin family; Region: PMP22_Claudin; cl21598\" /db_xref=\"CDD:473919\" variation 245 /gene=\"TMEM178A\" /gene_synonym=\"TMEM178\" /replace=\"a\" /replace=\"g\" /db_xref=\"dbSNP:2465487445\" variation 250 /gene=\"TMEM178A\" /gene_synonym=\"TMEM178\" /replace=\"c\" /replace=\"g\" /replace=\"t\" /db_xref=\"dbSNP:141844962\" variation...","source":"Homo sapiens (human)","symbol":"TMEM178A","synonym":"TMEM178","version":"XM_017003371.2"},{"aa_position":[],"accession":"NM_001425","definition":"Homo sapiens epithelial membrane protein 3 (MAM blood group) (EMP3), transcript variant 1, mRNA.","division":"RefSeq","geneid":"2014","gi":"","length":"649","nt_position":[],"snippet":"misc_feature 84..146 /gene=\"EMP3\" /gene_synonym=\"YMP\" /note=\"propagated from UniProtKB/Swiss-Prot (P54852.1); transmembrane region\" misc_feature 132..542 /gene=\"EMP3\" /gene_synonym=\"YMP\" /note=\"PMP-22/EMP/MP20/Claudin family; Region: PMP22_Claudin; cl21598\" /db_xref=\"CDD:473919\" misc_feature 213..215 /gene=\"EMP3\" /gene_synonym=\"YMP\" /note=\"N-linked (GlcNAc...) asparagine. /evidence=ECO:0000255; propagated from UniProtKB/Swiss-Prot (P54852.1); glycosylation site\" misc_feature 240..242 /gene=\"EMP3\" /gene_synonym=\"YMP\" /note=\"N-linked (GlcNAc...) asparagine. /evidence=ECO:0000255; propagated from...","source":"Homo sapiens (human)","symbol":"EMP3","synonym":"YMP","version":"NM_001425.3"},{"aa_position":[],"accession":"XM_006712288","definition":"PREDICTED: Homo sapiens transmembrane protein 182 (TMEM182), transcript variant X5, mRNA.","division":"RefSeq","geneid":"130827","gi":"","length":"2010","nt_position":[],"snippet":"protein 182 isoform X4\" /protein_id=\"XP_006712351.1\" /db_xref=\"GeneID:130827\" /db_xref=\"HGNC:HGNC:26391\" /translation=\"MRLNIAIFFGALFGALGVLLFLVAFGSDYWLLATEVGRCSGEKNIENVTFHHEGFFWRCWFNGIVEENDSNIWKFWYTNQPPSKNCTHAYLSPYPFMRGEHNSTSYDSAVSLL\" misc_feature 230..>523 /gene=\"TMEM182\" /note=\"PMP-22/EMP/MP20/Claudin family; Region: PMP22_Claudin; cl21598\" /db_xref=\"CDD:473919\" variation 190 /gene=\"TMEM182\" /replace=\"g\" /replace=\"t\" /db_xref=\"dbSNP:2466706475\" variation 192 /gene=\"TMEM182\" /replace=\"a\" /replace=\"g\" /db_xref=\"dbSNP:2466706482\" variation 194 /gene=\"TMEM182\" /replace=\"\" /replace=\"c\" /db_xref=\"...","source":"Homo sapiens (human)","symbol":"TMEM182","synonym":"","version":"XM_006712288.4"},{"aa_position":[],"accession":"NM_001330143","definition":"Homo sapiens peripheral myelin protein 22 (PMP22), transcript variant 8, mRNA.","division":"RefSeq","geneid":"5376","gi":"","length":"592","nt_position":[],"snippet":"PMP22\" /gene_synonym=\"CIDP; CMT1A; CMT1E; DSS; GAS-3; GAS3; HMSNIA; HNPP; Sp110\" /note=\"propagated from UniProtKB/Swiss-Prot (Q01453.1); transmembrane region\" misc_feature 271..>525 /gene=\"PMP22\" /gene_synonym=\"CIDP; CMT1A; CMT1E; DSS; GAS-3; GAS3; HMSNIA; HNPP; Sp110\" /note=\"PMP-22/EMP/MP20/Claudin family; Region: PMP22_Claudin; cl21598\" /db_xref=\"CDD:473919\" misc_feature 328..330 /gene=\"PMP22\" /gene_synonym=\"CIDP; CMT1A; CMT1E; DSS; GAS-3; GAS3; HMSNIA; HNPP; Sp110\" /note=\"N-linked (GlcNAc...) asparagine. /evidence=ECO:0000255; propagated from UniProtKB/Swiss-Prot (Q01453.1); glycosylation...","source":"Homo sapiens (human)","symbol":"PMP22","synonym":"CIDP; CMT1A; CMT1E; DSS; GAS-3; GAS3; HMSNIA; HNPP; Sp110","version":"NM_001330143.2"},{"aa_position":[],"accession":"NM_001167959","definition":"Homo sapiens transmembrane protein 178A (TMEM178A), transcript variant 2, mRNA.","division":"RefSeq","geneid":"130733","gi":"","length":"1364","nt_position":[],"snippet":"id=\"NP_001161431.1\" /db_xref=\"GeneID:130733\" /db_xref=\"HGNC:HGNC:28517\" /translation=\"MAVAVLLCGCIVATVSFFWEESLTQHVAGLLFLMTGIFCTISLCTYAASISYDLNRLPKLIYSLPADVEHGYSWSIFCAWCSLGFIVAAGGLCIAYPFISRTKIAQLKSGRDSTV\" misc_feature <308..580 /gene=\"TMEM178A\" /gene_synonym=\"TMEM178\" /note=\"PMP-22/EMP/MP20/Claudin family; Region: PMP22_Claudin; cl21598\" /db_xref=\"CDD:473919\" variation 305 /gene=\"TMEM178A\" /gene_synonym=\"TMEM178\" /replace=\"a\" /replace=\"g\" /db_xref=\"dbSNP:2465487445\" variation 310 /gene=\"TMEM178A\" /gene_synonym=\"TMEM178\" /replace=\"c\" /replace=\"g\" /replace=\"t\" /db_xref=\"dbSNP:141844962\" variation...","source":"Homo sapiens (human)","symbol":"TMEM178A","synonym":"TMEM178","version":"NM_001167959.2"},{"aa_position":[],"accession":"NR_133653","definition":"Homo sapiens RAB25, member RAS oncogene family (RAB25), transcript variant 2, non-coding RNA.","division":"RefSeq","geneid":"57111","gi":"","length":"904","nt_position":[],"snippet":"c\" /db_xref=\"dbSNP:2527718351\" ORIGIN // REFERENCE 1 (bases 1 to 904) AUTHORS Joshi,P., Ayyagari,V., Kandel,S., Modur,V., Iqbal,M.F., Robinson,K., Gao,J. and Rao,K. TITLE Loss of RAB25 Cooperates with Oncogenes in the Transformation of Human Mammary Epithelial Cells (HMECs) to Give Rise to Claudin-Low Tumors JOURNAL Biomed Res Int 2024, 8544837 (2024) PUBMED 38803515 REMARK GeneRIF: Loss of RAB25 Cooperates with Oncogenes in the Transformation of Human Mammary Epithelial Cells (HMECs) to Give Rise to Claudin-Low Tumors. Publication Status: Online-Only REFERENCE 2 (bases 1 to 904) AUTHORS Zhang...","source":"Homo sapiens (human)","symbol":"RAB25","synonym":"CATX-8; RAB11C","version":"NR_133653.2"},{"aa_position":[],"accession":"NM_031442","definition":"Homo sapiens transmembrane protein 47 (TMEM47), mRNA.","division":"RefSeq","geneid":"83604","gi":"","length":"4040","nt_position":[],"snippet":"CX788638.1 and AL596285.4. On Nov 22, 2018 this sequence version replaced NM_031442.3. Summary: This gene encodes a member of the PMP22/EMP/claudin protein family. The encoded protein is localized to the ER and the plasma membrane. In dogs, transcripts of this gene exist at high levels in the brain...Swiss-Prot (Q9BQJ4.1); acetylation site\" misc_feature 317..766 /gene=\"TMEM47\" /gene_synonym=\"BCMP1; TM4SF10; VAB-9\" /note=\"PMP-22/EMP/MP20/Claudin family; Region: PMP22_Claudin; cl21598\" /db_xref=\"CDD:473919\" misc_feature 317..379 /gene=\"TMEM47\" /gene_synonym=\"BCMP1; TM4SF10; VAB-9\" /note=\"...","source":"Homo sapiens (human)","symbol":"TMEM47","synonym":"BCMP1; TM4SF10; VAB-9","version":"NM_031442.4"},{"aa_position":[],"accession":"NR_110736","definition":"Homo sapiens transmembrane protein 114 (TMEM114), transcript variant 5, non-coding RNA.","division":"RefSeq","geneid":"283953","gi":"","length":"521","nt_position":[],"snippet":"PUBMED 22669729 REFERENCE 5 (bases 1 to 521) AUTHORS Maher,G.J., Hilton,E.N., Urquhart,J.E., Davidson,A.E., Spencer,H.L., Black,G.C. and Manson,F.D. TITLE The cataract-associated protein TMEM114, and TMEM235, are glycosylated transmembrane proteins that are distinct from claudin family members JOURNAL FEBS Lett 585 (14), 2187-2192 (2011) PUBMED 21689651 REMARK GeneRIF: Data demonstrate that TMEM114, and the closely related TMEM235, are closely related to members of the voltage dependent calcium channel gamma subunit family. REFERENCE 6 (bases 1 to 521) AUTHORS Mihelec,M., St Heaps,L., Flaherty...","source":"Homo sapiens (human)","symbol":"TMEM114","synonym":"","version":"NR_110736.2"},{"aa_position":[],"accession":"NM_001161748","definition":"Homo sapiens lens intrinsic membrane protein 2 (LIM2), transcript variant 2, mRNA.","division":"RefSeq","geneid":"3982","gi":"","length":"876","nt_position":[],"snippet":"MIM:154045\" /translation=\"MYSFMGGGLFCAWVGTILLVVAMATDHWMQYRLSGSFAHQGLWRYCLGNKCYLQTDSIAYWNATRAFMILSALCAISGIIMGIMAFAHQPTFSRISRPFSAGIMFFSSTLFVVLALAIYTGVTVSFLGRRFGDWRFSWSYILGWVAVLMTFFAGIFYMCAYRVHECRRLSTPR\" misc_feature 63..533 /gene=\"LIM2\" /gene_synonym=\"CTRCT19; MP17; MP19\" /note=\"PMP-22/EMP/MP20/Claudin family; Region: PMP22_Claudin; cl21598\" /db_xref=\"CDD:473919\" misc_feature 72..134 /gene=\"LIM2\" /gene_synonym=\"CTRCT19; MP17; MP19\" /note=\"propagated from UniProtKB/Swiss-Prot (P55344.2); transmembrane region\" misc_feature 189..191 /gene=\"LIM2\" /gene_synonym=\"CTRCT19; MP17; MP19\" /note=\"C-linked...","source":"Homo sapiens (human)","symbol":"LIM2","synonym":"CTRCT19; MP17; MP19","version":"NM_001161748.2"},{"aa_position":[],"accession":"XM_011545750","definition":"PREDICTED: Homo sapiens GSG1 like (GSG1L), transcript variant X1, mRNA.","division":"RefSeq","geneid":"146395","gi":"","length":"1331","nt_position":[],"snippet":"misc_feature 360..686 /gene=\"GSG1L\" /gene_synonym=\"PRO19651\" /note=\"GSG1-like protein; Region: GSG-1; pfam07803\" /db_xref=\"CDD:462270\" misc_feature <594..995 /gene=\"GSG1L\" /gene_synonym=\"PRO19651\" /note=\"PMP-22/EMP/MP20/Claudin family; Region: PMP22_Claudin; cl21598\" /db_xref=\"CDD:473919\" variation 293..294 /gene=\"GSG1L\" /gene_synonym=\"PRO19651\" /replace=\"\" /replace=\"ga\" /db_xref=\"dbSNP:2506724862\" variation 294 /gene=\"GSG1L\" /gene_synonym=\"PRO19651\" /replace=\"a\" /replace=\"g\" /db_xref=\"dbSNP:2506724854\" variation 295 /gene=\"GSG1L\" /gene_synonym=\"PRO19651\" /replace=\"a\" /replace=\"c\" /db_xref=\"...","source":"Homo sapiens (human)","symbol":"GSG1L","synonym":"PRO19651","version":"XM_011545750.3"},{"aa_position":[],"accession":"XM_005264145","definition":"PREDICTED: Homo sapiens transmembrane protein 178A (TMEM178A), transcript variant X3, mRNA.","division":"RefSeq","geneid":"130733","gi":"","length":"1412","nt_position":[],"snippet":"misc_feature 131..628 /gene=\"TMEM178A\" /gene_synonym=\"TMEM178\" /note=\"PMP-22/EMP/MP20/Claudin family; Region: PMP22_Claudin; cl21598\" /db_xref=\"CDD:473919\" variation 59 /gene=\"TMEM178A\" /gene_synonym=\"TMEM178\" /replace=\"a\" /replace=\"c\" /replace=\"t\" /db_xref=\"dbSNP:1478069949\" variation 62 /gene=\"TMEM178A\" /gene_synonym=\"TMEM178\" /replace=\"c\" /replace=\"g\" /db_xref=\"dbSNP:1003433093\" variation 63 /gene=\"TMEM178A\" /gene_synonym=\"TMEM178\" /replace=\"a\" /replace=\"g\" /db_xref=\"dbSNP:1670130006\" variation 64 /gene=\"TMEM178A\" /gene_synonym=\"TMEM178\" /replace=\"a\" /replace=\"g\" /replace=\"t\" /db_xref=\"...","source":"Homo sapiens (human)","symbol":"TMEM178A","synonym":"TMEM178","version":"XM_005264145.1"},{"aa_position":[],"accession":"NM_001697","definition":"Homo sapiens ATP synthase peripheral stalk subunit OSCP (ATP5PO), mRNA; nuclear gene for mitochondrial product.","division":"RefSeq","geneid":"539","gi":"","length":"756","nt_position":[],"snippet":"REMARK GeneRIF: A homozygous splice variant in ATP5PO, disrupts mitochondrial complex V function and causes Leigh syndrome in two unrelated families. REFERENCE 2 (bases 1 to 756) AUTHORS Yang,W., Zhang,K., Zhang,Z., Zhou,J., Li,L., Xu,Y., Qiu,J., Cai,L., Gong,Y. and Gong,K. TITLE Claudin-10 overexpression suppresses human clear cell renal cell carcinoma growth and metastasis by regulating ATP5O and causing mitochondrial dysfunction JOURNAL Int J Biol Sci 18 (6), 2329-2344 (2022) PUBMED 35414767 REMARK GeneRIF: Claudin-10 overexpression suppresses human clear cell renal cell carcinoma growth...","source":"Homo sapiens (human)","symbol":"ATP5PO","synonym":"ATP5O; ATPO; HMC08D05; MC5DN7; OSCP","version":"NM_001697.3"},{"aa_position":[],"accession":"NM_030657","definition":"Homo sapiens lens intrinsic membrane protein 2 (LIM2), transcript variant 1, mRNA.","division":"RefSeq","geneid":"3982","gi":"","length":"1002","nt_position":[],"snippet":"misc_feature 63..659 /gene=\"LIM2\" /gene_synonym=\"CTRCT19; MP17; MP19\" /note=\"PMP-22/EMP/MP20/Claudin family; Region: PMP22_Claudin; cl21598\" /db_xref=\"CDD:473919\" variation 63 /gene=\"LIM2\" /gene_synonym=\"CTRCT19; MP17; MP19\" /replace=\"a\" /replace=\"g\" /db_xref=\"dbSNP:2514207241\" variation 64 /gene=\"LIM2\" /gene_synonym=\"CTRCT19; MP17; MP19\" /replace=\"c\" /replace=\"g\" /replace=\"t\" /db_xref=\"dbSNP:200134867\" variation 65 /gene=\"LIM2\" /gene_synonym=\"CTRCT19; MP17; MP19\" /replace=\"a\" /replace=\"g\" /db_xref=\"dbSNP:1987101315\" variation 67 /gene=\"LIM2\" /gene_synonym=\"CTRCT19; MP17; MP19\" /replace=\"a\" /...","source":"Homo sapiens (human)","symbol":"LIM2","synonym":"CTRCT19; MP17; MP19","version":"NM_030657.4"},{"aa_position":[],"accession":"NM_001204212","definition":"Homo sapiens transmembrane protein 235 (TMEM235), transcript variant 3, mRNA.","division":"RefSeq","geneid":"283999","gi":"","length":"2289","nt_position":[],"snippet":"encoded by transcript variant 3; transmembrane protein ENSP364084; claudin-27\" /codon_start=1 /product=\"transmembrane protein 235 isoform 3\" /protein_id=\"NP_001191141.1\" /db_xref=\"CCDS:CCDS56048.1\" /db_xref=\"GeneID:283999\" /db_xref=\"HGNC:HGNC:27563\" /db_xref=\"MIM:620272\" /translation=\"MARLGALLLAAALGALLSFALLAAAVASDYWYILEVADAGNGSAWPGRAELLSSHSGLWRICEGVLTLAGVSIYISYSHLAFAETVQQYGPQHMQGVRVSFGWSMALAWGSCALEAFSGTLLLSAAWTLSLSPPICGHLSPQQVGGRGGD\" misc_feature <831..1013 /gene=\"TMEM235\" /gene_synonym=\"ARGM1\" /note=\"PMP-22/EMP/MP20/Claudin family; Region: PMP22_Claudin; cl21598\" /db_xref=\"CDD:473919\"...","source":"Homo sapiens (human)","symbol":"TMEM235","synonym":"ARGM1","version":"NM_001204212.2"},{"aa_position":[],"accession":"NM_001395503","definition":"Homo sapiens transmembrane protein 235 (TMEM235), transcript variant 6, mRNA.","division":"RefSeq","geneid":"283999","gi":"","length":"2260","nt_position":[],"snippet":"gene=\"TMEM235\" /gene_synonym=\"ARGM1\" /note=\"isoform 1 precursor is encoded by transcript variant 6; transmembrane protein ENSP364084; claudin-27\" /codon_start=1 /product=\"transmembrane protein 235 isoform 1 precursor\" /protein_id=\"NP_001382432.1\" /db_xref=\"CCDS:CCDS56046.1\" /db_xref=\"GeneID...ECO:0000255; propagated from UniProtKB/Swiss-Prot (A6NFC5.3)\" misc_feature 475..984 /gene=\"TMEM235\" /gene_synonym=\"ARGM1\" /note=\"PMP-22/EMP/MP20/Claudin tight junction; Region: Claudin_2; pfam13903\" /db_xref=\"CDD:372799\" mat_peptide 478..1062 /gene=\"TMEM235\" /gene_synonym=\"ARGM1\" /product=\"...","source":"Homo sapiens (human)","symbol":"TMEM235","synonym":"ARGM1","version":"NM_001395503.1"},{"aa_position":[],"accession":"NM_001371476","definition":"Homo sapiens calcium voltage-gated channel auxiliary subunit gamma 5 (CACNG5), transcript variant 2, mRNA.","division":"RefSeq","geneid":"27091","gi":"","length":"2001","nt_position":[],"snippet":"misc_feature 259..321 /gene=\"CACNG5\" /note=\"propagated from UniProtKB/Swiss-Prot (Q9UF02.2); transmembrane region\" misc_feature 289..>690 /gene=\"CACNG5\" /note=\"PMP-22/EMP/MP20/Claudin family; Region: PMP22_Claudin; cl21598\" /db_xref=\"CDD:473919\" misc_feature 544..606 /gene=\"CACNG5\" /note=\"propagated from UniProtKB/Swiss-Prot (Q9UF02.2); transmembrane region\" variation 238 /gene=\"CACNG5\" /replace=\"a\" /replace=\"g\" /db_xref=\"dbSNP:1977095183\" variation 240..242 /gene=\"CACNG5\" /replace=\"gag\" /replace=\"gaggag\" /db_xref=\"dbSNP:770695367\" variation 240 /gene=\"CACNG5\" /replace=\"g\" /replace=\"t\" /db_...","source":"Homo sapiens (human)","symbol":"CACNG5","synonym":"","version":"NM_001371476.1"},{"aa_position":[],"accession":"NM_001204211","definition":"Homo sapiens transmembrane protein 235 (TMEM235), transcript variant 2, mRNA.","division":"RefSeq","geneid":"283999","gi":"","length":"2427","nt_position":[],"snippet":"variant 2; transmembrane protein ENSP364084; claudin-27\" /codon_start=1 /product=\"transmembrane protein 235 isoform 2\" /protein_id=\"NP_001191140.1\" /db_xref=\"CCDS:CCDS56047.1\" /db_xref=\"GeneID:283999\" /db_xref=\"HGNC:HGNC:27563\" /db_xref=\"MIM:620272\" /translation=\"MARLGALLLAAALGALLSFALLAAAVASDYWYILEVADAGNGSAWPGRAELLSSHSGLWRICEVLHRAVIVVLPLSLVLLVCGWICGLLSSLAQSVSLLLFTGCYFLLGSVLTLAGVSIYISYSHLAFAETVQQYGPQHMQGVRVSFGWSMALAWGSCALEAFSGTLLLSAAWTLSLSPPICGHLSPQQVGGRGGD\" misc_feature 723..1151 /gene=\"TMEM235\" /gene_synonym=\"ARGM1\" /note=\"PMP-22/EMP/MP20/Claudin family; Region: PMP22_Claudin; cl21598\" /db_...","source":"Homo sapiens (human)","symbol":"TMEM235","synonym":"ARGM1","version":"NM_001204211.2"},{"aa_position":[],"accession":"NM_152390","definition":"Homo sapiens transmembrane protein 178A (TMEM178A), transcript variant 1, mRNA.","division":"RefSeq","geneid":"130733","gi":"","length":"1664","nt_position":[],"snippet":"Swiss-Prot (Q8NBL3.1)\" misc_feature 179..310 /gene=\"TMEM178A\" /gene_synonym=\"TMEM178\" /note=\"propagated from UniProtKB/Swiss-Prot (Q8NBL3.1); Region: Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite\" misc_feature 374..880 /gene=\"TMEM178A\" /gene_synonym=\"TMEM178\" /note=\"PMP-22/EMP/MP20/Claudin family; Region: PMP22_Claudin; cl21598\" /db_xref=\"CDD:473919\" misc_feature 530..532 /gene=\"TMEM178A\" /gene_synonym=\"TMEM178\" /note=\"N-linked (GlcNAc...) asparagine. /evidence=ECO:0000255; propagated from UniProtKB/Swiss-Prot (Q8NBL3.1); glycosylation site\" misc_feature 596..658 /gene=\"TMEM178A\" /gene_...","source":"Homo sapiens (human)","symbol":"TMEM178A","synonym":"TMEM178","version":"NM_152390.3"},{"aa_position":[],"accession":"NM_020387","definition":"Homo sapiens RAB25, member RAS oncogene family (RAB25), transcript variant 1, mRNA.","division":"RefSeq","geneid":"57111","gi":"","length":"1100","nt_position":[],"snippet":"c\" /db_xref=\"dbSNP:2527718351\" ORIGIN // REFERENCE 1 (bases 1 to 1100) AUTHORS Joshi,P., Ayyagari,V., Kandel,S., Modur,V., Iqbal,M.F., Robinson,K., Gao,J. and Rao,K. TITLE Loss of RAB25 Cooperates with Oncogenes in the Transformation of Human Mammary Epithelial Cells (HMECs) to Give Rise to Claudin-Low Tumors JOURNAL Biomed Res Int 2024, 8544837 (2024) PUBMED 38803515 REMARK GeneRIF: Loss of RAB25 Cooperates with Oncogenes in the Transformation of Human Mammary Epithelial Cells (HMECs) to Give Rise to Claudin-Low Tumors. Publication Status: Online-Only REFERENCE 2 (bases 1 to 1100) AUTHORS...","source":"Homo sapiens (human)","symbol":"RAB25","synonym":"CATX-8; RAB11C","version":"NM_020387.4"},{"aa_position":[],"accession":"NM_001278923","definition":"Homo sapiens annexin A8 like 1 (ANXA8L1), transcript variant 3, mRNA.","division":"RefSeq","geneid":"728113","gi":"","length":"1737","nt_position":[],"snippet":"Z.E., Illei,P.B., Ashfaq,R., Infante,J.R., Murphy,K., Pandey,A., Schulick,R., Winter,J., Sharma,R., Maitra,A., Goggins,M. and Hruban,R.H. TITLE New markers of pancreatic cancer identified through differential gene expression analyses: claudin 18 and annexin A8 JOURNAL Am J Surg Pathol 32 (2), 188-196 (2008) PUBMED 18223320 REMARK GeneRIF: Claudin 18 and annexin A8 are frequently highly overexpressed in infiltrating ductal adenocarcinomas. REFERENCE 2 (bases 1 to 1737) AUTHORS Gerke,V., Creutz,C.E. and Moss,S.E. TITLE Annexins: linking Ca2+ signalling to membrane dynamics JOURNAL Nat Rev Mol...","source":"Homo sapiens (human)","symbol":"ANXA8L1","synonym":"ANXA8; ANXA8L2; bA145E20.2; VAC-beta","version":"NM_001278923.2"},{"aa_position":[],"accession":"NM_001278924","definition":"Homo sapiens annexin A8 like 1 (ANXA8L1), transcript variant 2, mRNA.","division":"RefSeq","geneid":"728113","gi":"","length":"1755","nt_position":[],"snippet":"Z.E., Illei,P.B., Ashfaq,R., Infante,J.R., Murphy,K., Pandey,A., Schulick,R., Winter,J., Sharma,R., Maitra,A., Goggins,M. and Hruban,R.H. TITLE New markers of pancreatic cancer identified through differential gene expression analyses: claudin 18 and annexin A8 JOURNAL Am J Surg Pathol 32 (2), 188-196 (2008) PUBMED 18223320 REMARK GeneRIF: Claudin 18 and annexin A8 are frequently highly overexpressed in infiltrating ductal adenocarcinomas. REFERENCE 2 (bases 1 to 1755) AUTHORS Gerke,V., Creutz,C.E. and Moss,S.E. TITLE Annexins: linking Ca2+ signalling to membrane dynamics JOURNAL Nat Rev Mol...","source":"Homo sapiens (human)","symbol":"ANXA8L1","synonym":"ANXA8; ANXA8L2; bA145E20.2; VAC-beta","version":"NM_001278924.2"},{"aa_position":[],"accession":"NM_001318755","definition":"Homo sapiens transmembrane protein 25 (TMEM25), transcript variant 7, mRNA.","division":"RefSeq","geneid":"84866","gi":"","length":"1416","nt_position":[],"snippet":"and integrated analysis of the potential function of TMEM25 in renal clear cell carcinoma with low expression status. REFERENCE 2 (bases 1 to 1416) AUTHORS Kamakura,S., Hayase,J., Kohda,A., Iwakiri,Y., Chishiki,K., Izaki,T. and Sumimoto,H. TITLE TMEM25 is a Par3-binding protein that attenuates claudin assembly during tight junction development JOURNAL EMBO Rep 25 (1), 144-167 (2024) PUBMED 38177906 REMARK GeneRIF: TMEM25 is a Par3-binding protein that attenuates claudin assembly during tight junction development. REFERENCE 3 (bases 1 to 1416) AUTHORS An,B., Ando,A., Akuta,H., Morishita,F. and...","source":"Homo sapiens (human)","symbol":"TMEM25","synonym":"","version":"NM_001318755.2"},{"aa_position":[],"accession":"NM_006539","definition":"Homo sapiens calcium voltage-gated channel auxiliary subunit gamma 3 (CACNG3), mRNA.","division":"RefSeq","geneid":"10368","gi":"","length":"1917","nt_position":[],"snippet":"misc_feature 436..1008 /gene=\"CACNG3\" /note=\"PMP-22/EMP/MP20/Claudin family; Region: PMP22_Claudin; cl21598\" /db_xref=\"CDD:473919\" misc_feature 442..504 /gene=\"CACNG3\" /note=\"propagated from UniProtKB/Swiss-Prot (O60359.1); transmembrane region\" misc_feature 730..792 /gene=\"CACNG3\" /note=\"propagated from UniProtKB/Swiss-Prot (O60359.1); transmembrane region\" misc_feature 823..885 /gene=\"CACNG3\" /note=\"propagated from UniProtKB/Swiss-Prot (O60359.1); transmembrane region\" misc_feature 961..1023 /gene=\"CACNG3\" /note=\"propagated from UniProtKB/Swiss-Prot (O60359.1); transmembrane region\" misc_...","source":"Homo sapiens (human)","symbol":"CACNG3","synonym":"","version":"NM_006539.4"},{"aa_position":[],"accession":"XM_017024461","definition":"PREDICTED: Homo sapiens transmembrane protein 235 (TMEM235), transcript variant X5, mRNA.","division":"RefSeq","geneid":"283999","gi":"","length":"1916","nt_position":[],"snippet":"misc_feature 299..>625 /gene=\"TMEM235\" /gene_synonym=\"ARGM1\" /note=\"PMP-22/EMP/MP20/Claudin family; Region: PMP22_Claudin; cl21598\" /db_xref=\"CDD:473919\" variation 218 /gene=\"TMEM235\" /gene_synonym=\"ARGM1\" /replace=\"a\" /replace=\"c\" /replace=\"g\" /db_xref=\"dbSNP:867349976\" variation 219 /gene=\"TMEM235\" /gene_synonym=\"ARGM1\" /replace=\"a\" /replace=\"t\" /db_xref=\"dbSNP:1025207372\" variation 220 /gene=\"TMEM235\" /gene_synonym=\"ARGM1\" /replace=\"a\" /replace=\"c\" /replace=\"g\" /db_xref=\"dbSNP:1312298646\" variation 221 /gene=\"TMEM235\" /gene_synonym=\"ARGM1\" /replace=\"a\" /replace=\"g\" /db_xref=\"dbSNP...","source":"Homo sapiens (human)","symbol":"TMEM235","synonym":"ARGM1","version":"XM_017024461.2"},{"aa_position":[],"accession":"NM_001204210","definition":"Homo sapiens transmembrane protein 235 (TMEM235), transcript variant 1, mRNA.","division":"RefSeq","geneid":"283999","gi":"","length":"2508","nt_position":[],"snippet":"gene=\"TMEM235\" /gene_synonym=\"ARGM1\" /note=\"isoform 1 precursor is encoded by transcript variant 1; transmembrane protein ENSP364084; claudin-27\" /codon_start=1 /product=\"transmembrane protein 235 isoform 1 precursor\" /protein_id=\"NP_001191139.1\" /db_xref=\"CCDS:CCDS56046.1\" /db_xref=\"GeneID...ECO:0000255; propagated from UniProtKB/Swiss-Prot (A6NFC5.3)\" misc_feature 723..1232 /gene=\"TMEM235\" /gene_synonym=\"ARGM1\" /note=\"PMP-22/EMP/MP20/Claudin tight junction; Region: Claudin_2; pfam13903\" /db_xref=\"CDD:372799\" mat_peptide 726..1310 /gene=\"TMEM235\" /gene_synonym=\"ARGM1\" /product=\"...","source":"Homo sapiens (human)","symbol":"TMEM235","synonym":"ARGM1","version":"NM_001204210.2"},{"aa_position":[],"accession":"NR_168056","definition":"Homo sapiens ubiquitin specific peptidase 40 (USP40), transcript variant 19, non-coding RNA.","division":"RefSeq","geneid":"55230","gi":"","length":"2609","nt_position":[],"snippet":"feedback loop. REFERENCE 2 (bases 1 to 2609) AUTHORS Wu,Q., Qiu,Y., Guo,J., Yuan,Z., Yang,Y., Zhu,Q., Zhang,Z., Guo,J., Wu,Y., Zhang,J., Huang,D., Tu,K. and Hu,X. TITLE USP40 promotes hepatocellular carcinoma cell proliferation, migration and stemness by deubiquitinating and stabilizing Claudin1 JOURNAL Biol Direct 19 (1), 13 (2024) PUBMED 38308285 REMARK GeneRIF: USP40 promotes hepatocellular carcinoma cell proliferation, migration and stemness by deubiquitinating and stabilizing Claudin1. Publication Status: Online-Only REFERENCE 3 (bases 1 to 2609) AUTHORS Miao,J., Li,L., Shaheen,N., Wei,J...","source":"Homo sapiens (human)","symbol":"USP40","synonym":"","version":"NR_168056.1"},{"aa_position":[],"accession":"NM_000727","definition":"Homo sapiens calcium voltage-gated channel auxiliary subunit gamma 1 (CACNG1), mRNA.","division":"RefSeq","geneid":"786","gi":"","length":"1302","nt_position":[],"snippet":"misc_feature 138..194 /gene=\"CACNG1\" /gene_synonym=\"CACNLG\" /note=\"propagated from UniProtKB/Swiss-Prot (Q06432.1); transmembrane region\" misc_feature 162..674 /gene=\"CACNG1\" /gene_synonym=\"CACNLG\" /note=\"PMP-22/EMP/MP20/Claudin tight junction; Region: Claudin_2; pfam13903\" /db_xref=\"CDD:372799\" misc_feature 234..236 /gene=\"CACNG1\" /gene_synonym=\"CACNLG\" /note=\"N-linked (GlcNAc...) asparagine. /evidence=ECO:0000255; propagated from UniProtKB/Swiss-Prot (Q06432.1); glycosylation site\" misc_feature 342..344 /gene=\"CACNG1\" /gene_synonym=\"CACNLG\" /note=\"N-linked (GlcNAc...) asparagine. /evidence=...","source":"Homo sapiens (human)","symbol":"CACNG1","synonym":"CACNLG","version":"NM_000727.4"},{"aa_position":[],"accession":"NM_001388480","definition":"Homo sapiens transmembrane protein 235 (TMEM235), transcript variant 4, mRNA.","division":"RefSeq","geneid":"283999","gi":"","length":"2667","nt_position":[],"snippet":"ENSP364084; claudin-27\" /codon_start=1 /product=\"transmembrane protein 235 isoform 4\" /protein_id=\"NP_001375409.1\" /db_xref=\"GeneID:283999\" /db_xref=\"HGNC:HGNC:27563\" /db_xref=\"MIM:620272\" /translation=\"MARLGALLLAAALGALLSFALLAAAVASDYWYILEVADAGNGSAWPGRAELLSSHSGLWRICEGQNGCIPLVDPFASESLDVSTSVQHLISLLPLPLRFQEDVSTQTCPSAVLLSLTTVLHRAVIVVLPLSLVLLVCGWICGLLSSLAQSVSLLLFTGCYFLLGTLTTCRVLAKCSSEGSSEGPPVPAAGVLTLAGVSIYISYSHLAFAETVQQYGPQHMQGVRVSFGWSMALAWGSCALEAFSGTLLLSAAWTLSLSPPICGHLSPQQVGGRGGD\" misc_feature 723..1391 /gene=\"TMEM235\" /gene_synonym=\"ARGM1\" /note=\"PMP-22/EMP/MP20/Claudin tight junction; Region:...","source":"Homo sapiens (human)","symbol":"TMEM235","synonym":"ARGM1","version":"NM_001388480.1"},{"aa_position":[],"accession":"NM_001382302","definition":"Homo sapiens ubiquitin specific peptidase 40 (USP40), transcript variant 10, mRNA.","division":"RefSeq","geneid":"55230","gi":"","length":"2736","nt_position":[],"snippet":"feedback loop. REFERENCE 2 (bases 1 to 2736) AUTHORS Wu,Q., Qiu,Y., Guo,J., Yuan,Z., Yang,Y., Zhu,Q., Zhang,Z., Guo,J., Wu,Y., Zhang,J., Huang,D., Tu,K. and Hu,X. TITLE USP40 promotes hepatocellular carcinoma cell proliferation, migration and stemness by deubiquitinating and stabilizing Claudin1 JOURNAL Biol Direct 19 (1), 13 (2024) PUBMED 38308285 REMARK GeneRIF: USP40 promotes hepatocellular carcinoma cell proliferation, migration and stemness by deubiquitinating and stabilizing Claudin1. Publication Status: Online-Only REFERENCE 3 (bases 1 to 2736) AUTHORS Miao,J., Li,L., Shaheen,N., Wei,J...","source":"Homo sapiens (human)","symbol":"USP40","synonym":"","version":"NM_001382302.1"},{"aa_position":[],"accession":"NM_001098845","definition":"Homo sapiens annexin A8 like 1 (ANXA8L1), transcript variant 1, mRNA.","division":"RefSeq","geneid":"728113","gi":"","length":"1908","nt_position":[],"snippet":"Z.E., Illei,P.B., Ashfaq,R., Infante,J.R., Murphy,K., Pandey,A., Schulick,R., Winter,J., Sharma,R., Maitra,A., Goggins,M. and Hruban,R.H. TITLE New markers of pancreatic cancer identified through differential gene expression analyses: claudin 18 and annexin A8 JOURNAL Am J Surg Pathol 32 (2), 188-196 (2008) PUBMED 18223320 REMARK GeneRIF: Claudin 18 and annexin A8 are frequently highly overexpressed in infiltrating ductal adenocarcinomas. REFERENCE 2 (bases 1 to 1908) AUTHORS Gerke,V., Creutz,C.E. and Moss,S.E. TITLE Annexins: linking Ca2+ signalling to membrane dynamics JOURNAL Nat Rev Mol...","source":"Homo sapiens (human)","symbol":"ANXA8L1","synonym":"ANXA8; ANXA8L2; bA145E20.2; VAC-beta","version":"NM_001098845.3"},{"aa_position":[],"accession":"NM_001388481","definition":"Homo sapiens transmembrane protein 235 (TMEM235), transcript variant 5, mRNA.","division":"RefSeq","geneid":"283999","gi":"","length":"2805","nt_position":[],"snippet":"CDS 642..1610 /gene=\"TMEM235\" /gene_synonym=\"ARGM1\" /note=\"isoform 5 is encoded by transcript variant 5; transmembrane protein ENSP364084; claudin-27\" /codon_start=1 /product=\"transmembrane protein 235 isoform 5\" /protein_id=\"NP_001375410.1\" /db_xref=\"CCDS:CCDS92405.1\" /db_xref=\"GeneID:283999\" /db_...misc_feature 723..1529 /gene=\"TMEM235\" /gene_synonym=\"ARGM1\" /note=\"PMP-22/EMP/MP20/Claudin family; Region: PMP22_Claudin; cl21598\" /db_xref=\"CDD:473919\" variation 642 /gene=\"TMEM235\" /gene_synonym=\"ARGM1\" /replace=\"a\" /replace=\"c\" /replace=\"g\" /db_xref=\"dbSNP:867349976\" variation 643 /gene=\"...","source":"Homo sapiens (human)","symbol":"TMEM235","synonym":"ARGM1","version":"NM_001388481.1"},{"aa_position":[],"accession":"NM_007193","definition":"Homo sapiens annexin A10 (ANXA10), mRNA.","division":"RefSeq","geneid":"11199","gi":"","length":"1441","nt_position":[],"snippet":"and Metastasis Via the miR-580-3p/ANXA10 Pathway. REFERENCE 2 (bases 1 to 1441) AUTHORS Isidro RA, Abukhiran I, Dunseth CD, Gosse MD, Humble RM, Pelletier DJ, Varshney N, Bellizzi AM and Hornick JL. TITLE Strong Annexin A10 Expression Supports a Pancreatic Primary and Combined Annexin A10, Claudin 18, and SOX2 Expression Supports an Esophagogastric Origin in Carcinomas of Unknown Primary JOURNAL Am J Surg Pathol 47 (4), 440-452 (2023) PUBMED 36730833 REMARK GeneRIF: Strong Annexin A10 Expression Supports a Pancreatic Primary and Combined Annexin A10, Claudin 18, and SOX2 Expression Supports an...","source":"Homo sapiens (human)","symbol":"ANXA10","synonym":"ANX14","version":"NM_007193.5"},{"aa_position":[],"accession":"NM_001310219","definition":"Homo sapiens GSG1 like 2 (GSG1L2), mRNA.","division":"RefSeq","geneid":"644070","gi":"","length":"2668","nt_position":[],"snippet":"sig_peptide 9..95 /gene=\"GSG1L2\" /inference=\"COORDINATES: ab initio prediction:SignalP:4.0\" misc_feature 69..365 /gene=\"GSG1L2\" /note=\"GSG1-like protein; Region: GSG-1; pfam07803\" /db_xref=\"CDD:462270\" misc_feature <273..674 /gene=\"GSG1L2\" /note=\"PMP-22/EMP/MP20/Claudin family; Region: PMP22_Claudin; cl21598\" /db_xref=\"CDD:473919\" variation 9 /gene=\"GSG1L2\" /replace=\"a\" /replace=\"g\" /replace=\"t\" /db_xref=\"dbSNP:1440036493\" variation 10 /gene=\"GSG1L2\" /replace=\"a\" /replace=\"c\" /replace=\"t\" /db_xref=\"dbSNP:1323706033\" variation 12 /gene=\"GSG1L2\" /replace=\"a\" /replace=\"c\" /replace=\"g\" /db_xref=\"...","source":"Homo sapiens (human)","symbol":"GSG1L2","synonym":"","version":"NM_001310219.2"},{"aa_position":[],"accession":"NM_001166343","definition":"Homo sapiens MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase (MFNG), transcript variant 2, mRNA.","division":"RefSeq","geneid":"4242","gi":"","length":"2031","nt_position":[],"snippet":"is distinct from other glycosyltransferases, these proteins have a fucose-specific beta-1,3-N-acetylglucosaminyltransferase activity that leads to elongation of O-linked fucose residues on Notch, which alters Notch signaling. The protein encoded by this gene may control Notch signaling in claudin-low breast cancer. [provided by RefSeq, May 2018]. Transcript Variant: This variant (2) uses an alternate splice site in the 5' exon and lacks an alternate 5' coding exon, compared to variant 1, resulting in a protein that maintains the reading frame but is shorter, compared to isoform 1. Publication...","source":"Homo sapiens (human)","symbol":"MFNG","synonym":"","version":"NM_001166343.2"},{"aa_position":[],"accession":"NR_029413","definition":"Homo sapiens MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase (MFNG), transcript variant 3, non-coding RNA.","division":"RefSeq","geneid":"4242","gi":"","length":"2024","nt_position":[],"snippet":"is distinct from other glycosyltransferases, these proteins have a fucose-specific beta-1,3-N-acetylglucosaminyltransferase activity that leads to elongation of O-linked fucose residues on Notch, which alters Notch signaling. The protein encoded by this gene may control Notch signaling in claudin-low breast cancer. [provided by RefSeq, May 2018]. Transcript Variant: This variant (3) lacks an alternate internal exon, compared to variant 1. This variant is represented as non-coding because the use of the 5'-most supported translational start codon, as used in variant 1, renders the transcript a...","source":"Homo sapiens (human)","symbol":"MFNG","synonym":"","version":"NR_029413.2"},{"aa_position":[],"accession":"XM_017011636","definition":"PREDICTED: Homo sapiens transmembrane protein 178B (TMEM178B), transcript variant X2, mRNA.","division":"RefSeq","geneid":"100507421","gi":"","length":"3982","nt_position":[],"snippet":"MAAGRLLLYTGLSLALCALGMLAVAICSDHWYETDARKHRDRCKAFNTRRVDPGFIYLPLRASRSRLDRWEGKLLRARNRRQLFAMSPADECSRQYNSTNMGLWRKCHRQGFDPEIAALIRKGEIERCTYIKYHYSSATIPRNLTFNITKTIRQDEWHALHLRRMTAGFMGMAVAIILFGWIIGVLGCCWDRGLMQYVAGLLFLMGGKTGGIKECLPQPGQG\" misc_feature 545..>898 /gene=\"TMEM178B\" /note=\"PMP-22/EMP/MP20/Claudin family; Region: PMP22_Claudin; cl21598\" /db_xref=\"CDD:473919\" variation 248 /gene=\"TMEM178B\" /replace=\"a\" /replace=\"c\" /db_xref=\"dbSNP:1794559263\" variation 250 /gene=\"TMEM178B\" /replace=\"a\" /replace=\"g\" /db_xref=\"dbSNP:1465631743\" variation 251 /gene=\"TMEM178B\" /replace=\"a\" /replace=\"g\" /db_xref=\"dbSNP...","source":"Homo sapiens (human)","symbol":"TMEM178B","synonym":"","version":"XM_017011636.2"},{"aa_position":[],"accession":"NR_134852","definition":"Homo sapiens transmembrane protein 25 (TMEM25), transcript variant 9, non-coding RNA.","division":"RefSeq","geneid":"84866","gi":"","length":"1879","nt_position":[],"snippet":"and integrated analysis of the potential function of TMEM25 in renal clear cell carcinoma with low expression status. REFERENCE 2 (bases 1 to 1879) AUTHORS Kamakura,S., Hayase,J., Kohda,A., Iwakiri,Y., Chishiki,K., Izaki,T. and Sumimoto,H. TITLE TMEM25 is a Par3-binding protein that attenuates claudin assembly during tight junction development JOURNAL EMBO Rep 25 (1), 144-167 (2024) PUBMED 38177906 REMARK GeneRIF: TMEM25 is a Par3-binding protein that attenuates claudin assembly during tight junction development. REFERENCE 3 (bases 1 to 1879) AUTHORS An,B., Ando,A., Akuta,H., Morishita,F. and...","source":"Homo sapiens (human)","symbol":"TMEM25","synonym":"","version":"NR_134852.2"},{"aa_position":[],"accession":"NM_002405","definition":"Homo sapiens MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase (MFNG), transcript variant 1, mRNA.","division":"RefSeq","geneid":"4242","gi":"","length":"2073","nt_position":[],"snippet":"is distinct from other glycosyltransferases, these proteins have a fucose-specific beta-1,3-N-acetylglucosaminyltransferase activity that leads to elongation of O-linked fucose residues on Notch, which alters Notch signaling. The protein encoded by this gene may control Notch signaling in claudin-low breast cancer. [provided by RefSeq, May 2018]. Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to...","source":"Homo sapiens (human)","symbol":"MFNG","synonym":"","version":"NM_002405.4"},{"aa_position":[],"accession":"NM_001144038","definition":"Homo sapiens transmembrane protein 25 (TMEM25), transcript variant 5, mRNA.","division":"RefSeq","geneid":"84866","gi":"","length":"2130","nt_position":[],"snippet":"and integrated analysis of the potential function of TMEM25 in renal clear cell carcinoma with low expression status. REFERENCE 2 (bases 1 to 2130) AUTHORS Kamakura,S., Hayase,J., Kohda,A., Iwakiri,Y., Chishiki,K., Izaki,T. and Sumimoto,H. TITLE TMEM25 is a Par3-binding protein that attenuates claudin assembly during tight junction development JOURNAL EMBO Rep 25 (1), 144-167 (2024) PUBMED 38177906 REMARK GeneRIF: TMEM25 is a Par3-binding protein that attenuates claudin assembly during tight junction development. REFERENCE 3 (bases 1 to 2130) AUTHORS An,B., Ando,A., Akuta,H., Morishita,F. and...","source":"Homo sapiens (human)","symbol":"TMEM25","synonym":"","version":"NM_001144038.2"},{"aa_position":[],"accession":"XM_017024459","definition":"PREDICTED: Homo sapiens transmembrane protein 235 (TMEM235), transcript variant X3, mRNA.","division":"RefSeq","geneid":"283999","gi":"","length":"2148","nt_position":[],"snippet":"misc_feature 299..883 /gene=\"TMEM235\" /gene_synonym=\"ARGM1\" /note=\"PMP-22/EMP/MP20/Claudin tight junction; Region: Claudin_2; pfam13903\" /db_xref=\"CDD:372799\" variation 218 /gene=\"TMEM235\" /gene_synonym=\"ARGM1\" /replace=\"a\" /replace=\"c\" /replace=\"g\" /db_xref=\"dbSNP:867349976\" variation 219 /gene=\"TMEM235\" /gene_synonym=\"ARGM1\" /replace=\"a\" /replace=\"t\" /db_xref=\"dbSNP:1025207372\" variation 220 /gene=\"TMEM235\" /gene_synonym=\"ARGM1\" /replace=\"a\" /replace=\"c\" /replace=\"g\" /db_xref=\"dbSNP:1312298646\" variation 221 /gene=\"TMEM235\" /gene_synonym=\"ARGM1\" /replace=\"a\" /replace=\"g\" /db_xref=\"dbSNP...","source":"Homo sapiens (human)","symbol":"TMEM235","synonym":"ARGM1","version":"XM_017024459.2"},{"aa_position":[],"accession":"XM_047435763","definition":"PREDICTED: Homo sapiens transmembrane protein 235 (TMEM235), transcript variant X4, mRNA.","division":"RefSeq","geneid":"283999","gi":"","length":"2159","nt_position":[],"snippet":"misc_feature 299..883 /gene=\"TMEM235\" /gene_synonym=\"ARGM1\" /note=\"PMP-22/EMP/MP20/Claudin tight junction; Region: Claudin_2; pfam13903\" /db_xref=\"CDD:372799\" variation 218 /gene=\"TMEM235\" /gene_synonym=\"ARGM1\" /replace=\"a\" /replace=\"c\" /replace=\"g\" /db_xref=\"dbSNP:867349976\" variation 219 /gene=\"TMEM235\" /gene_synonym=\"ARGM1\" /replace=\"a\" /replace=\"t\" /db_xref=\"dbSNP:1025207372\" variation 220 /gene=\"TMEM235\" /gene_synonym=\"ARGM1\" /replace=\"a\" /replace=\"c\" /replace=\"g\" /db_xref=\"dbSNP:1312298646\" variation 221 /gene=\"TMEM235\" /gene_synonym=\"ARGM1\" /replace=\"a\" /replace=\"g\" /db_xref=\"dbSNP...","source":"Homo sapiens (human)","symbol":"TMEM235","synonym":"ARGM1","version":"XM_047435763.1"},{"aa_position":[],"accession":"XM_011524620","definition":"PREDICTED: Homo sapiens transmembrane protein 235 (TMEM235), transcript variant X1, mRNA.","division":"RefSeq","geneid":"283999","gi":"","length":"2235","nt_position":[],"snippet":"misc_feature 299..970 /gene=\"TMEM235\" /gene_synonym=\"ARGM1\" /note=\"PMP-22/EMP/MP20/Claudin tight junction; Region: Claudin_2; pfam13903\" /db_xref=\"CDD:372799\" variation 218 /gene=\"TMEM235\" /gene_synonym=\"ARGM1\" /replace=\"a\" /replace=\"c\" /replace=\"g\" /db_xref=\"dbSNP:867349976\" variation 219 /gene=\"TMEM235\" /gene_synonym=\"ARGM1\" /replace=\"a\" /replace=\"t\" /db_xref=\"dbSNP:1025207372\" variation 220 /gene=\"TMEM235\" /gene_synonym=\"ARGM1\" /replace=\"a\" /replace=\"c\" /replace=\"g\" /db_xref=\"dbSNP:1312298646\" variation 221 /gene=\"TMEM235\" /gene_synonym=\"ARGM1\" /replace=\"a\" /replace=\"g\" /db_xref=\"dbSNP...","source":"Homo sapiens (human)","symbol":"TMEM235","synonym":"ARGM1","version":"XM_011524620.3"},{"aa_position":[],"accession":"NM_001144036","definition":"Homo sapiens transmembrane protein 25 (TMEM25), transcript variant 3, mRNA.","division":"RefSeq","geneid":"84866","gi":"","length":"1976","nt_position":[],"snippet":"and integrated analysis of the potential function of TMEM25 in renal clear cell carcinoma with low expression status. REFERENCE 2 (bases 1 to 1976) AUTHORS Kamakura,S., Hayase,J., Kohda,A., Iwakiri,Y., Chishiki,K., Izaki,T. and Sumimoto,H. TITLE TMEM25 is a Par3-binding protein that attenuates claudin assembly during tight junction development JOURNAL EMBO Rep 25 (1), 144-167 (2024) PUBMED 38177906 REMARK GeneRIF: TMEM25 is a Par3-binding protein that attenuates claudin assembly during tight junction development. REFERENCE 3 (bases 1 to 1976) AUTHORS An,B., Ando,A., Akuta,H., Morishita,F. and...","source":"Homo sapiens (human)","symbol":"TMEM25","synonym":"","version":"NM_001144036.2"},{"aa_position":[],"accession":"NM_001260490","definition":"Homo sapiens lipolysis stimulated lipoprotein receptor (LSR), transcript variant 5, mRNA.","division":"RefSeq","geneid":"51599","gi":"","length":"1608","nt_position":[],"snippet":"REFERENCE 2 (bases 1 to 1608) AUTHORS Arai,W., Konno,T., Kohno,T., Kodera,Y., Tsujiwaki,M., Shindo,Y., Chiba,H., Miyajima,M., Sakuma,Y., Watanabe,A. and Kojima,T. TITLE Downregulation of angulin-1/LSR induces malignancy via upregulation of EGF-dependent claudin-2 and TGF-beta-dependent cell metabolism in human lung adenocarcinoma A549 cells JOURNAL Oncotarget 14, 261-275 (2023) PUBMED 36961882 REMARK GeneRIF: Downregulation of angulin-1/LSR induces malignancy via upregulation of EGF-dependent claudin-2 and TGF-beta-dependent cell metabolism in human lung...","source":"Homo sapiens (human)","symbol":"LSR","synonym":"ILDR3; LISCH7","version":"NM_001260490.2"},{"aa_position":[],"accession":"NM_000048","definition":"Homo sapiens argininosuccinate lyase (ASL), transcript variant 2, mRNA.","division":"RefSeq","geneid":"435","gi":"","length":"2140","nt_position":[],"snippet":"AUTHORS Kho,J., Polak,U., Jiang,M.M., Odom,J.D., Hunter,J.V., Ali,S.M., Burrage,L.C., Nagamani,S.C., Pautler,R.G., Thompson,H.P., Urayama,A., Jin,Z. and Lee,B. TITLE Argininosuccinate lyase deficiency causes blood-brain barrier disruption via nitric oxide-mediated dysregulation of claudin expression JOURNAL JCI Insight 8 (17), e168475 (2023) PUBMED 37490345 REMARK GeneRIF: Argininosuccinate lyase deficiency causes blood-brain barrier disruption via nitric oxide-mediated dysregulation of claudin expression. Publication Status: Online-Only REFERENCE 2 (bases 1 to 2140) AUTHORS Kido,J.,...","source":"Homo sapiens (human)","symbol":"ASL","synonym":"ASAL; ASLD","version":"NM_000048.4"},{"aa_position":[],"accession":"NM_001144037","definition":"Homo sapiens transmembrane protein 25 (TMEM25), transcript variant 4, mRNA.","division":"RefSeq","geneid":"84866","gi":"","length":"2265","nt_position":[],"snippet":"and integrated analysis of the potential function of TMEM25 in renal clear cell carcinoma with low expression status. REFERENCE 2 (bases 1 to 2265) AUTHORS Kamakura,S., Hayase,J., Kohda,A., Iwakiri,Y., Chishiki,K., Izaki,T. and Sumimoto,H. TITLE TMEM25 is a Par3-binding protein that attenuates claudin assembly during tight junction development JOURNAL EMBO Rep 25 (1), 144-167 (2024) PUBMED 38177906 REMARK GeneRIF: TMEM25 is a Par3-binding protein that attenuates claudin assembly during tight junction development. REFERENCE 3 (bases 1 to 2265) AUTHORS An,B., Ando,A., Akuta,H., Morishita,F. and...","source":"Homo sapiens (human)","symbol":"TMEM25","synonym":"","version":"NM_001144037.2"},{"aa_position":[],"accession":"XM_017003375","definition":"PREDICTED: Homo sapiens transmembrane protein 182 (TMEM182), transcript variant X2, mRNA.","division":"RefSeq","geneid":"130827","gi":"","length":"3450","nt_position":[],"snippet":"db_xref=\"HGNC:HGNC:26391\" /translation=\"MRLNIAIFFGALFGALGVLLFLVAFGSDYWLLATEVGRCSGEKNIENVTFHHEGFFWRCWFNGIVEENDSNIWKFWYTNQPPSKNCTHAYLSPYPFMRGEHNSTSYDSAVSILFSLVVMLYVIWVQAVADMESYRNMKMKDCLDFTPSVLYGWSFFLAPAGIFFSLLAGLLFLVVGWHIQIHH\" misc_feature 230..709 /gene=\"TMEM182\" /note=\"PMP-22/EMP/MP20/Claudin family; Region: PMP22_Claudin; cl21598\" /db_xref=\"CDD:473919\" variation 190 /gene=\"TMEM182\" /replace=\"g\" /replace=\"t\" /db_xref=\"dbSNP:2466706475\" variation 192 /gene=\"TMEM182\" /replace=\"a\" /replace=\"g\" /db_xref=\"dbSNP:2466706482\" variation 194 /gene=\"TMEM182\" /replace=\"\" /replace=\"c\" /db_xref=\"dbSNP...","source":"Homo sapiens (human)","symbol":"TMEM182","synonym":"","version":"XM_017003375.2"},{"aa_position":[],"accession":"XM_047435762","definition":"PREDICTED: Homo sapiens transmembrane protein 235 (TMEM235), transcript variant X2, mRNA.","division":"RefSeq","geneid":"283999","gi":"","length":"2351","nt_position":[],"snippet":"misc_feature 566..1075 /gene=\"TMEM235\" /gene_synonym=\"ARGM1\" /note=\"PMP-22/EMP/MP20/Claudin tight junction; Region: Claudin_2; pfam13903\" /db_xref=\"CDD:372799\" variation 182 /gene=\"TMEM235\" /gene_synonym=\"ARGM1\" /replace=\"a\" /replace=\"g\" /db_xref=\"dbSNP:1444469283\" variation 184 /gene=\"TMEM235\" /gene_synonym=\"ARGM1\" /replace=\"a\" /replace=\"g\" /db_xref=\"dbSNP:2510942322\" variation 186 /gene=\"TMEM235\" /gene_synonym=\"ARGM1\" /replace=\"c\" /replace=\"t\" /db_xref=\"dbSNP:1424385165\" variation 187 /gene=\"TMEM235\" /gene_synonym=\"ARGM1\" /replace=\"a\" /replace=\"g\" /db_xref=\"dbSNP:1262934174\" variation 190 /...","source":"Homo sapiens (human)","symbol":"TMEM235","synonym":"ARGM1","version":"XM_047435762.1"},{"aa_position":[],"accession":"NM_001024946","definition":"Homo sapiens argininosuccinate lyase (ASL), transcript variant 4, mRNA.","division":"RefSeq","geneid":"435","gi":"","length":"2244","nt_position":[],"snippet":"AUTHORS Kho,J., Polak,U., Jiang,M.M., Odom,J.D., Hunter,J.V., Ali,S.M., Burrage,L.C., Nagamani,S.C., Pautler,R.G., Thompson,H.P., Urayama,A., Jin,Z. and Lee,B. TITLE Argininosuccinate lyase deficiency causes blood-brain barrier disruption via nitric oxide-mediated dysregulation of claudin expression JOURNAL JCI Insight 8 (17), e168475 (2023) PUBMED 37490345 REMARK GeneRIF: Argininosuccinate lyase deficiency causes blood-brain barrier disruption via nitric oxide-mediated dysregulation of claudin expression. Publication Status: Online-Only REFERENCE 2 (bases 1 to 2244) AUTHORS Kido,J.,...","source":"Homo sapiens (human)","symbol":"ASL","synonym":"ASAL; ASLD","version":"NM_001024946.2"},{"aa_position":[],"accession":"NR_168055","definition":"Homo sapiens ubiquitin specific peptidase 40 (USP40), transcript variant 18, non-coding RNA.","division":"RefSeq","geneid":"55230","gi":"","length":"3558","nt_position":[],"snippet":"feedback loop. REFERENCE 2 (bases 1 to 3558) AUTHORS Wu,Q., Qiu,Y., Guo,J., Yuan,Z., Yang,Y., Zhu,Q., Zhang,Z., Guo,J., Wu,Y., Zhang,J., Huang,D., Tu,K. and Hu,X. TITLE USP40 promotes hepatocellular carcinoma cell proliferation, migration and stemness by deubiquitinating and stabilizing Claudin1 JOURNAL Biol Direct 19 (1), 13 (2024) PUBMED 38308285 REMARK GeneRIF: USP40 promotes hepatocellular carcinoma cell proliferation, migration and stemness by deubiquitinating and stabilizing Claudin1. Publication Status: Online-Only REFERENCE 3 (bases 1 to 3558) AUTHORS Miao,J., Li,L., Shaheen,N., Wei,J...","source":"Homo sapiens (human)","symbol":"USP40","synonym":"","version":"NR_168055.1"},{"aa_position":[],"accession":"NM_001382301","definition":"Homo sapiens ubiquitin specific peptidase 40 (USP40), transcript variant 9, mRNA.","division":"RefSeq","geneid":"55230","gi":"","length":"3038","nt_position":[],"snippet":"feedback loop. REFERENCE 2 (bases 1 to 3038) AUTHORS Wu,Q., Qiu,Y., Guo,J., Yuan,Z., Yang,Y., Zhu,Q., Zhang,Z., Guo,J., Wu,Y., Zhang,J., Huang,D., Tu,K. and Hu,X. TITLE USP40 promotes hepatocellular carcinoma cell proliferation, migration and stemness by deubiquitinating and stabilizing Claudin1 JOURNAL Biol Direct 19 (1), 13 (2024) PUBMED 38308285 REMARK GeneRIF: USP40 promotes hepatocellular carcinoma cell proliferation, migration and stemness by deubiquitinating and stabilizing Claudin1. Publication Status: Online-Only REFERENCE 3 (bases 1 to 3038) AUTHORS Miao,J., Li,L., Shaheen,N., Wei,J...","source":"Homo sapiens (human)","symbol":"USP40","synonym":"","version":"NM_001382301.1"},{"aa_position":[],"accession":"NM_031897","definition":"Homo sapiens calcium voltage-gated channel auxiliary subunit gamma 6 (CACNG6), transcript variant 3, mRNA.","division":"RefSeq","geneid":"59285","gi":"","length":"2288","nt_position":[],"snippet":"note=\"propagated from UniProtKB/Swiss-Prot (Q9BXT2.1); Region: Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite\" misc_feature 1368..1430 /gene=\"CACNG6\" /note=\"propagated from UniProtKB/Swiss-Prot (Q9BXT2.1); transmembrane region\" misc_feature 1401..1748 /gene=\"CACNG6\" /note=\"PMP-22/EMP/MP20/Claudin family; Region: PMP22_Claudin; cl21598\" /db_xref=\"CDD:473919\" variation 1243 /gene=\"CACNG6\" /replace=\"c\" /replace=\"t\" /db_xref=\"dbSNP:778346177\" variation 1245 /gene=\"CACNG6\" /replace=\"a\" /replace=\"c\" /replace=\"t\" /db_xref=\"dbSNP:2069476315\" variation 1246 /gene=\"CACNG6\" /replace=\"c\" /replace=\"t\" /...","source":"Homo sapiens (human)","symbol":"CACNG6","synonym":"","version":"NM_031897.3"},{"aa_position":[],"accession":"NM_001385215","definition":"Homo sapiens lipolysis stimulated lipoprotein receptor (LSR), transcript variant 6, mRNA.","division":"RefSeq","geneid":"51599","gi":"","length":"1725","nt_position":[],"snippet":"REFERENCE 2 (bases 1 to 1725) AUTHORS Arai,W., Konno,T., Kohno,T., Kodera,Y., Tsujiwaki,M., Shindo,Y., Chiba,H., Miyajima,M., Sakuma,Y., Watanabe,A. and Kojima,T. TITLE Downregulation of angulin-1/LSR induces malignancy via upregulation of EGF-dependent claudin-2 and TGF-beta-dependent cell metabolism in human lung adenocarcinoma A549 cells JOURNAL Oncotarget 14, 261-275 (2023) PUBMED 36961882 REMARK GeneRIF: Downregulation of angulin-1/LSR induces malignancy via upregulation of EGF-dependent claudin-2 and TGF-beta-dependent cell metabolism in human lung...","source":"Homo sapiens (human)","symbol":"LSR","synonym":"ILDR3; LISCH7","version":"NM_001385215.1"},{"aa_position":[],"accession":"NM_001024944","definition":"Homo sapiens argininosuccinate lyase (ASL), transcript variant 3, mRNA.","division":"RefSeq","geneid":"435","gi":"","length":"2262","nt_position":[],"snippet":"AUTHORS Kho,J., Polak,U., Jiang,M.M., Odom,J.D., Hunter,J.V., Ali,S.M., Burrage,L.C., Nagamani,S.C., Pautler,R.G., Thompson,H.P., Urayama,A., Jin,Z. and Lee,B. TITLE Argininosuccinate lyase deficiency causes blood-brain barrier disruption via nitric oxide-mediated dysregulation of claudin expression JOURNAL JCI Insight 8 (17), e168475 (2023) PUBMED 37490345 REMARK GeneRIF: Argininosuccinate lyase deficiency causes blood-brain barrier disruption via nitric oxide-mediated dysregulation of claudin expression. Publication Status: Online-Only REFERENCE 2 (bases 1 to 2262) AUTHORS Kido,J.,...","source":"Homo sapiens (human)","symbol":"ASL","synonym":"ASAL; ASLD","version":"NM_001024944.2"},{"aa_position":[],"accession":"NM_205835","definition":"Homo sapiens lipolysis stimulated lipoprotein receptor (LSR), transcript variant 3, mRNA.","division":"RefSeq","geneid":"51599","gi":"","length":"1728","nt_position":[],"snippet":"REFERENCE 2 (bases 1 to 1728) AUTHORS Arai,W., Konno,T., Kohno,T., Kodera,Y., Tsujiwaki,M., Shindo,Y., Chiba,H., Miyajima,M., Sakuma,Y., Watanabe,A. and Kojima,T. TITLE Downregulation of angulin-1/LSR induces malignancy via upregulation of EGF-dependent claudin-2 and TGF-beta-dependent cell metabolism in human lung adenocarcinoma A549 cells JOURNAL Oncotarget 14, 261-275 (2023) PUBMED 36961882 REMARK GeneRIF: Downregulation of angulin-1/LSR induces malignancy via upregulation of EGF-dependent claudin-2 and TGF-beta-dependent cell metabolism in human lung...","source":"Homo sapiens (human)","symbol":"LSR","synonym":"ILDR3; LISCH7","version":"NM_205835.4"},{"aa_position":[],"accession":"NM_014405","definition":"Homo sapiens calcium voltage-gated channel auxiliary subunit gamma 4 (CACNG4), mRNA.","division":"RefSeq","geneid":"27092","gi":"","length":"3583","nt_position":[],"snippet":"misc_feature 221..811 /gene=\"CACNG4\" /note=\"PMP-22/EMP/MP20/Claudin family; Region: PMP22_Claudin; cl21598\" /db_xref=\"CDD:473919\" misc_feature 233..295 /gene=\"CACNG4\" /note=\"propagated from UniProtKB/Swiss-Prot (Q9UBN1.1); transmembrane region\" misc_feature 329..331 /gene=\"CACNG4\" /note=\"N-linked (GlcNAc...) asparagine. /evidence=ECO:0000255; propagated from UniProtKB/Swiss-Prot (Q9UBN1.1); glycosylation site\" misc_feature 338..340 /gene=\"CACNG4\" /note=\"N-linked (GlcNAc...) asparagine. /evidence=ECO:0000255; propagated from UniProtKB/Swiss-Prot (Q9UBN1.1); glycosylation site\" misc_feature...","source":"Homo sapiens (human)","symbol":"CACNG4","synonym":"","version":"NM_014405.4"},{"aa_position":[],"accession":"NM_001318757","definition":"Homo sapiens transmembrane protein 25 (TMEM25), transcript variant 8, mRNA.","division":"RefSeq","geneid":"84866","gi":"","length":"2129","nt_position":[],"snippet":"and integrated analysis of the potential function of TMEM25 in renal clear cell carcinoma with low expression status. REFERENCE 2 (bases 1 to 2129) AUTHORS Kamakura,S., Hayase,J., Kohda,A., Iwakiri,Y., Chishiki,K., Izaki,T. and Sumimoto,H. TITLE TMEM25 is a Par3-binding protein that attenuates claudin assembly during tight junction development JOURNAL EMBO Rep 25 (1), 144-167 (2024) PUBMED 38177906 REMARK GeneRIF: TMEM25 is a Par3-binding protein that attenuates claudin assembly during tight junction development. REFERENCE 3 (bases 1 to 2129) AUTHORS An,B., Ando,A., Akuta,H., Morishita,F. and...","source":"Homo sapiens (human)","symbol":"TMEM25","synonym":"","version":"NM_001318757.2"},{"aa_position":[],"accession":"NM_145815","definition":"Homo sapiens calcium voltage-gated channel auxiliary subunit gamma 6 (CACNG6), transcript variant 2, mRNA.","division":"RefSeq","geneid":"59285","gi":"","length":"2363","nt_position":[],"snippet":"translation=\"MMWSNFFLQEENRRRGAAGRRRAHGQGRSGLTPEREGKVKLALLLAAVGATLAVLSVGTEFWVELNTYKANGSAVCEAAHLGLWKACTKRLWQADVPVDRDTCGPAELPGEANCTYFKFFTTGENARIFQRTTKKGLLLLVSLEVFRHSVRALLQRVSPEPPPAPRLTYEYSWSLGCGVGAGLILLLGAGCFLLLTLPSWPWGSLCPKRGHRAT\" misc_feature 1401..1823 /gene=\"CACNG6\" /note=\"PMP-22/EMP/MP20/Claudin family; Region: PMP22_Claudin; cl21598\" /db_xref=\"CDD:473919\" variation 1243 /gene=\"CACNG6\" /replace=\"c\" /replace=\"t\" /db_xref=\"dbSNP:778346177\" variation 1245 /gene=\"CACNG6\" /replace=\"a\" /replace=\"c\" /replace=\"t\" /db_xref=\"dbSNP:2069476315\" variation 1246 /gene=\"CACNG6\" /replace=\"c\" /replace=\"t\" /db...","source":"Homo sapiens (human)","symbol":"CACNG6","synonym":"","version":"NM_145815.2"},{"aa_position":[],"accession":"NM_001024943","definition":"Homo sapiens argininosuccinate lyase (ASL), transcript variant 1, mRNA.","division":"RefSeq","geneid":"435","gi":"","length":"2322","nt_position":[],"snippet":"AUTHORS Kho,J., Polak,U., Jiang,M.M., Odom,J.D., Hunter,J.V., Ali,S.M., Burrage,L.C., Nagamani,S.C., Pautler,R.G., Thompson,H.P., Urayama,A., Jin,Z. and Lee,B. TITLE Argininosuccinate lyase deficiency causes blood-brain barrier disruption via nitric oxide-mediated dysregulation of claudin expression JOURNAL JCI Insight 8 (17), e168475 (2023) PUBMED 37490345 REMARK GeneRIF: Argininosuccinate lyase deficiency causes blood-brain barrier disruption via nitric oxide-mediated dysregulation of claudin expression. Publication Status: Online-Only REFERENCE 2 (bases 1 to 2322) AUTHORS Kido,J.,...","source":"Homo sapiens (human)","symbol":"ASL","synonym":"ASAL; ASLD","version":"NM_001024943.2"},{"aa_position":[],"accession":"NM_001260489","definition":"Homo sapiens lipolysis stimulated lipoprotein receptor (LSR), transcript variant 4, mRNA.","division":"RefSeq","geneid":"51599","gi":"","length":"1872","nt_position":[],"snippet":"REFERENCE 2 (bases 1 to 1872) AUTHORS Arai,W., Konno,T., Kohno,T., Kodera,Y., Tsujiwaki,M., Shindo,Y., Chiba,H., Miyajima,M., Sakuma,Y., Watanabe,A. and Kojima,T. TITLE Downregulation of angulin-1/LSR induces malignancy via upregulation of EGF-dependent claudin-2 and TGF-beta-dependent cell metabolism in human lung adenocarcinoma A549 cells JOURNAL Oncotarget 14, 261-275 (2023) PUBMED 36961882 REMARK GeneRIF: Downregulation of angulin-1/LSR induces malignancy via upregulation of EGF-dependent claudin-2 and TGF-beta-dependent cell metabolism in human lung...","source":"Homo sapiens (human)","symbol":"LSR","synonym":"ILDR3; LISCH7","version":"NM_001260489.2"},{"aa_position":[],"accession":"NM_015925","definition":"Homo sapiens lipolysis stimulated lipoprotein receptor (LSR), transcript variant 1, mRNA.","division":"RefSeq","geneid":"51599","gi":"","length":"1875","nt_position":[],"snippet":"REFERENCE 2 (bases 1 to 1875) AUTHORS Arai,W., Konno,T., Kohno,T., Kodera,Y., Tsujiwaki,M., Shindo,Y., Chiba,H., Miyajima,M., Sakuma,Y., Watanabe,A. and Kojima,T. TITLE Downregulation of angulin-1/LSR induces malignancy via upregulation of EGF-dependent claudin-2 and TGF-beta-dependent cell metabolism in human lung adenocarcinoma A549 cells JOURNAL Oncotarget 14, 261-275 (2023) PUBMED 36961882 REMARK GeneRIF: Downregulation of angulin-1/LSR induces malignancy via upregulation of EGF-dependent claudin-2 and TGF-beta-dependent cell metabolism in human lung...","source":"Homo sapiens (human)","symbol":"LSR","synonym":"ILDR3; LISCH7","version":"NM_015925.7"},{"aa_position":[],"accession":"NM_205834","definition":"Homo sapiens lipolysis stimulated lipoprotein receptor (LSR), transcript variant 2, mRNA.","division":"RefSeq","geneid":"51599","gi":"","length":"1932","nt_position":[],"snippet":"REFERENCE 2 (bases 1 to 1932) AUTHORS Arai,W., Konno,T., Kohno,T., Kodera,Y., Tsujiwaki,M., Shindo,Y., Chiba,H., Miyajima,M., Sakuma,Y., Watanabe,A. and Kojima,T. TITLE Downregulation of angulin-1/LSR induces malignancy via upregulation of EGF-dependent claudin-2 and TGF-beta-dependent cell metabolism in human lung adenocarcinoma A549 cells JOURNAL Oncotarget 14, 261-275 (2023) PUBMED 36961882 REMARK GeneRIF: Downregulation of angulin-1/LSR induces malignancy via upregulation of EGF-dependent claudin-2 and TGF-beta-dependent cell metabolism in human lung...","source":"Homo sapiens (human)","symbol":"LSR","synonym":"ILDR3; LISCH7","version":"NM_205834.4"},{"aa_position":[],"accession":"NM_001384801","definition":"Homo sapiens calcium voltage-gated channel auxiliary subunit gamma 7 (CACNG7), transcript variant 2, mRNA.","division":"RefSeq","geneid":"59284","gi":"","length":"2608","nt_position":[],"snippet":"misc_feature 291..353 /gene=\"CACNG7\" /note=\"propagated from UniProtKB/Swiss-Prot (P62955.1); transmembrane region\" misc_feature 321..>698 /gene=\"CACNG7\" /note=\"PMP-22/EMP/MP20/Claudin family; Region: PMP22_Claudin; cl21598\" /db_xref=\"CDD:473919\" misc_feature 576..638 /gene=\"CACNG7\" /note=\"propagated from UniProtKB/Swiss-Prot (P62955.1); transmembrane region\" misc_feature <753..1142 /gene=\"CACNG7\" /note=\"EBNA-3B; Provisional; Region: PHA03378\" /db_xref=\"CDD:223065\" variation 271..297 /gene=\"CACNG7\" /replace=\"tga\" /replace=\"tgagtcactgcagcagccgcgccctga\" /db_xref=\"dbSNP:1399685190\" variation 272 /...","source":"Homo sapiens (human)","symbol":"CACNG7","synonym":"","version":"NM_001384801.1"},{"aa_position":[],"accession":"NM_145814","definition":"Homo sapiens calcium voltage-gated channel auxiliary subunit gamma 6 (CACNG6), transcript variant 1, mRNA.","division":"RefSeq","geneid":"59285","gi":"","length":"2501","nt_position":[],"snippet":"note=\"propagated from UniProtKB/Swiss-Prot (Q9BXT2.1); Region: Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite\" misc_feature 1368..1430 /gene=\"CACNG6\" /note=\"propagated from UniProtKB/Swiss-Prot (Q9BXT2.1); transmembrane region\" misc_feature 1401..1961 /gene=\"CACNG6\" /note=\"PMP-22/EMP/MP20/Claudin family; Region: PMP22_Claudin; cl21598\" /db_xref=\"CDD:473919\" misc_feature 1668..1730 /gene=\"CACNG6\" /note=\"propagated from UniProtKB/Swiss-Prot (Q9BXT2.1); transmembrane region\" misc_feature 1746..1808 /gene=\"CACNG6\" /note=\"propagated from UniProtKB/Swiss-Prot (Q9BXT2.1); transmembrane region\"...","source":"Homo sapiens (human)","symbol":"CACNG6","synonym":"","version":"NM_145814.2"},{"aa_position":[],"accession":"NM_001144035","definition":"Homo sapiens transmembrane protein 25 (TMEM25), transcript variant 6, mRNA.","division":"RefSeq","geneid":"84866","gi":"","length":"2285","nt_position":[],"snippet":"and integrated analysis of the potential function of TMEM25 in renal clear cell carcinoma with low expression status. REFERENCE 2 (bases 1 to 2285) AUTHORS Kamakura,S., Hayase,J., Kohda,A., Iwakiri,Y., Chishiki,K., Izaki,T. and Sumimoto,H. TITLE TMEM25 is a Par3-binding protein that attenuates claudin assembly during tight junction development JOURNAL EMBO Rep 25 (1), 144-167 (2024) PUBMED 38177906 REMARK GeneRIF: TMEM25 is a Par3-binding protein that attenuates claudin assembly during tight junction development. REFERENCE 3 (bases 1 to 2285) AUTHORS An,B., Ando,A., Akuta,H., Morishita,F. and...","source":"Homo sapiens (human)","symbol":"TMEM25","synonym":"","version":"NM_001144035.2"},{"aa_position":[],"accession":"NM_001144034","definition":"Homo sapiens transmembrane protein 25 (TMEM25), transcript variant 2, mRNA.","division":"RefSeq","geneid":"84866","gi":"","length":"2288","nt_position":[],"snippet":"and integrated analysis of the potential function of TMEM25 in renal clear cell carcinoma with low expression status. REFERENCE 2 (bases 1 to 2288) AUTHORS Kamakura,S., Hayase,J., Kohda,A., Iwakiri,Y., Chishiki,K., Izaki,T. and Sumimoto,H. TITLE TMEM25 is a Par3-binding protein that attenuates claudin assembly during tight junction development JOURNAL EMBO Rep 25 (1), 144-167 (2024) PUBMED 38177906 REMARK GeneRIF: TMEM25 is a Par3-binding protein that attenuates claudin assembly during tight junction development. REFERENCE 3 (bases 1 to 2288) AUTHORS An,B., Ando,A., Akuta,H., Morishita,F. and...","source":"Homo sapiens (human)","symbol":"TMEM25","synonym":"","version":"NM_001144034.2"},{"aa_position":[],"accession":"NM_001256541","definition":"Homo sapiens transmembrane protein 204 (TMEM204), transcript variant 2, mRNA.","division":"RefSeq","geneid":"79652","gi":"","length":"1684","nt_position":[],"snippet":"gene_synonym=\"C16orf30; CLP24\" /replace=\"a\" /replace=\"c\" /replace=\"t\" /db_xref=\"dbSNP:374458197\" variation 461 /gene=\"TMEM204\" /gene_synonym=\"C16orf30; CLP24\" /replace=\"a\" /replace=\"g\" /replace=\"t\" /db_xref=\"dbSNP:79799097\" CDS 462..1142 /gene=\"TMEM204\" /gene_synonym=\"C16orf30; CLP24\" /note=\"claudin-like protein 24; claudin-like protein of 24 kDa\" /codon_start=1 /product=\"transmembrane protein 204\" /protein_id=\"NP_001243470.1\" /db_xref=\"CCDS:CCDS42098.1\" /db_xref=\"GeneID:79652\" /db_xref=\"HGNC:HGNC:14158\" /db_xref=\"MIM:611002\" /translation=\"...","source":"Homo sapiens (human)","symbol":"TMEM204","synonym":"C16orf30; CLP24","version":"NM_001256541.2"},{"aa_position":[],"accession":"NM_001382299","definition":"Homo sapiens ubiquitin specific peptidase 40 (USP40), transcript variant 7, mRNA.","division":"RefSeq","geneid":"55230","gi":"","length":"3495","nt_position":[],"snippet":"feedback loop. REFERENCE 2 (bases 1 to 3495) AUTHORS Wu,Q., Qiu,Y., Guo,J., Yuan,Z., Yang,Y., Zhu,Q., Zhang,Z., Guo,J., Wu,Y., Zhang,J., Huang,D., Tu,K. and Hu,X. TITLE USP40 promotes hepatocellular carcinoma cell proliferation, migration and stemness by deubiquitinating and stabilizing Claudin1 JOURNAL Biol Direct 19 (1), 13 (2024) PUBMED 38308285 REMARK GeneRIF: USP40 promotes hepatocellular carcinoma cell proliferation, migration and stemness by deubiquitinating and stabilizing Claudin1. Publication Status: Online-Only REFERENCE 3 (bases 1 to 3495) AUTHORS Miao,J., Li,L., Shaheen,N., Wei,J...","source":"Homo sapiens (human)","symbol":"USP40","synonym":"","version":"NM_001382299.1"},{"aa_position":[],"accession":"NM_024600","definition":"Homo sapiens transmembrane protein 204 (TMEM204), transcript variant 1, mRNA.","division":"RefSeq","geneid":"79652","gi":"","length":"1833","nt_position":[],"snippet":"gene_synonym=\"C16orf30; CLP24\" /replace=\"a\" /replace=\"c\" /replace=\"t\" /db_xref=\"dbSNP:374458197\" variation 610 /gene=\"TMEM204\" /gene_synonym=\"C16orf30; CLP24\" /replace=\"a\" /replace=\"g\" /replace=\"t\" /db_xref=\"dbSNP:79799097\" CDS 611..1291 /gene=\"TMEM204\" /gene_synonym=\"C16orf30; CLP24\" /note=\"claudin-like protein 24; claudin-like protein of 24 kDa\" /codon_start=1 /product=\"transmembrane protein 204\" /protein_id=\"NP_078876.2\" /db_xref=\"CCDS:CCDS42098.1\" /db_xref=\"GeneID:79652\" /db_xref=\"HGNC:HGNC:14158\" /db_xref=\"MIM:611002\" /translation=\"...","source":"Homo sapiens (human)","symbol":"TMEM204","synonym":"C16orf30; CLP24","version":"NM_024600.6"},{"aa_position":[],"accession":"NM_031896","definition":"Homo sapiens calcium voltage-gated channel auxiliary subunit gamma 7 (CACNG7), transcript variant 1, mRNA.","division":"RefSeq","geneid":"59284","gi":"","length":"2754","nt_position":[],"snippet":"misc_feature 291..353 /gene=\"CACNG7\" /note=\"propagated from UniProtKB/Swiss-Prot (P62955.1); transmembrane region\" misc_feature 315..854 /gene=\"CACNG7\" /note=\"PMP-22/EMP/MP20/Claudin family; Region: PMP22_Claudin; cl21598\" /db_xref=\"CDD:473919\" misc_feature 576..638 /gene=\"CACNG7\" /note=\"propagated from UniProtKB/Swiss-Prot (P62955.1); transmembrane region\" misc_feature 654..716 /gene=\"CACNG7\" /note=\"propagated from UniProtKB/Swiss-Prot (P62955.1); transmembrane region\" misc_feature 804..866 /gene=\"CACNG7\" /note=\"propagated from UniProtKB/Swiss-Prot (P62955.1); transmembrane region\" misc_...","source":"Homo sapiens (human)","symbol":"CACNG7","synonym":"","version":"NM_031896.5"},{"aa_position":[],"accession":"NM_032780","definition":"Homo sapiens transmembrane protein 25 (TMEM25), transcript variant 1, mRNA.","division":"RefSeq","geneid":"84866","gi":"","length":"2420","nt_position":[],"snippet":"and integrated analysis of the potential function of TMEM25 in renal clear cell carcinoma with low expression status. REFERENCE 2 (bases 1 to 2420) AUTHORS Kamakura,S., Hayase,J., Kohda,A., Iwakiri,Y., Chishiki,K., Izaki,T. and Sumimoto,H. TITLE TMEM25 is a Par3-binding protein that attenuates claudin assembly during tight junction development JOURNAL EMBO Rep 25 (1), 144-167 (2024) PUBMED 38177906 REMARK GeneRIF: TMEM25 is a Par3-binding protein that attenuates claudin assembly during tight junction development. REFERENCE 3 (bases 1 to 2420) AUTHORS An,B., Ando,A., Akuta,H., Morishita,F. and...","source":"Homo sapiens (human)","symbol":"TMEM25","synonym":"","version":"NM_032780.4"},{"aa_position":[],"accession":"NR_168051","definition":"Homo sapiens ubiquitin specific peptidase 40 (USP40), transcript variant 14, non-coding RNA.","division":"RefSeq","geneid":"55230","gi":"","length":"3681","nt_position":[],"snippet":"feedback loop. REFERENCE 2 (bases 1 to 3681) AUTHORS Wu,Q., Qiu,Y., Guo,J., Yuan,Z., Yang,Y., Zhu,Q., Zhang,Z., Guo,J., Wu,Y., Zhang,J., Huang,D., Tu,K. and Hu,X. TITLE USP40 promotes hepatocellular carcinoma cell proliferation, migration and stemness by deubiquitinating and stabilizing Claudin1 JOURNAL Biol Direct 19 (1), 13 (2024) PUBMED 38308285 REMARK GeneRIF: USP40 promotes hepatocellular carcinoma cell proliferation, migration and stemness by deubiquitinating and stabilizing Claudin1. Publication Status: Online-Only REFERENCE 3 (bases 1 to 3681) AUTHORS Miao,J., Li,L., Shaheen,N., Wei,J...","source":"Homo sapiens (human)","symbol":"USP40","synonym":"","version":"NR_168051.1"},{"aa_position":[],"accession":"NM_001382300","definition":"Homo sapiens ubiquitin specific peptidase 40 (USP40), transcript variant 8, mRNA.","division":"RefSeq","geneid":"55230","gi":"","length":"3641","nt_position":[],"snippet":"feedback loop. REFERENCE 2 (bases 1 to 3641) AUTHORS Wu,Q., Qiu,Y., Guo,J., Yuan,Z., Yang,Y., Zhu,Q., Zhang,Z., Guo,J., Wu,Y., Zhang,J., Huang,D., Tu,K. and Hu,X. TITLE USP40 promotes hepatocellular carcinoma cell proliferation, migration and stemness by deubiquitinating and stabilizing Claudin1 JOURNAL Biol Direct 19 (1), 13 (2024) PUBMED 38308285 REMARK GeneRIF: USP40 promotes hepatocellular carcinoma cell proliferation, migration and stemness by deubiquitinating and stabilizing Claudin1. Publication Status: Online-Only REFERENCE 3 (bases 1 to 3641) AUTHORS Miao,J., Li,L., Shaheen,N., Wei,J...","source":"Homo sapiens (human)","symbol":"USP40","synonym":"","version":"NM_001382300.1"},{"aa_position":[],"accession":"NM_001382297","definition":"Homo sapiens ubiquitin specific peptidase 40 (USP40), transcript variant 5, mRNA.","division":"RefSeq","geneid":"55230","gi":"","length":"3651","nt_position":[],"snippet":"feedback loop. REFERENCE 2 (bases 1 to 3651) AUTHORS Wu,Q., Qiu,Y., Guo,J., Yuan,Z., Yang,Y., Zhu,Q., Zhang,Z., Guo,J., Wu,Y., Zhang,J., Huang,D., Tu,K. and Hu,X. TITLE USP40 promotes hepatocellular carcinoma cell proliferation, migration and stemness by deubiquitinating and stabilizing Claudin1 JOURNAL Biol Direct 19 (1), 13 (2024) PUBMED 38308285 REMARK GeneRIF: USP40 promotes hepatocellular carcinoma cell proliferation, migration and stemness by deubiquitinating and stabilizing Claudin1. Publication Status: Online-Only REFERENCE 3 (bases 1 to 3651) AUTHORS Miao,J., Li,L., Shaheen,N., Wei,J...","source":"Homo sapiens (human)","symbol":"USP40","synonym":"","version":"NM_001382297.1"},{"aa_position":[],"accession":"NR_168050","definition":"Homo sapiens ubiquitin specific peptidase 40 (USP40), transcript variant 13, non-coding RNA.","division":"RefSeq","geneid":"55230","gi":"","length":"3757","nt_position":[],"snippet":"feedback loop. REFERENCE 2 (bases 1 to 3757) AUTHORS Wu,Q., Qiu,Y., Guo,J., Yuan,Z., Yang,Y., Zhu,Q., Zhang,Z., Guo,J., Wu,Y., Zhang,J., Huang,D., Tu,K. and Hu,X. TITLE USP40 promotes hepatocellular carcinoma cell proliferation, migration and stemness by deubiquitinating and stabilizing Claudin1 JOURNAL Biol Direct 19 (1), 13 (2024) PUBMED 38308285 REMARK GeneRIF: USP40 promotes hepatocellular carcinoma cell proliferation, migration and stemness by deubiquitinating and stabilizing Claudin1. Publication Status: Online-Only REFERENCE 3 (bases 1 to 3757) AUTHORS Miao,J., Li,L., Shaheen,N., Wei,J...","source":"Homo sapiens (human)","symbol":"USP40","synonym":"","version":"NR_168050.1"},{"aa_position":[],"accession":"NM_153322","definition":"Homo sapiens peripheral myelin protein 22 (PMP22), transcript variant 3, mRNA.","division":"RefSeq","geneid":"5376","gi":"","length":"1714","nt_position":[],"snippet":"MSIIVLHVAVLVLLFVSTIVSQWIVGNGHATDLWQNCSTSSSGNVHHCFSSSPNEWLQSVQATMILSIIFSILSLFLFFCQLFTLTKGGRFYITGIFQILAGLCVMSAAAIYTVRHPEWHLNSDYSYGFAYILAWVAFPLALLSGVIYVILRKRE\" misc_feature 94..552 /gene=\"PMP22\" /gene_synonym=\"CIDP; CMT1A; CMT1E; DSS; GAS-3; GAS3; HMSNIA; HNPP; Sp110\" /note=\"PMP-22/EMP/MP20/Claudin family; Region: PMP22_Claudin; pfam00822\" /db_xref=\"CDD:395662\" misc_feature 97..186 /gene=\"PMP22\" /gene_synonym=\"CIDP; CMT1A; CMT1E; DSS; GAS-3; GAS3; HMSNIA; HNPP; Sp110\" /note=\"propagated from UniProtKB/Swiss-Prot (Q01453.1); transmembrane region\" misc_feature 214..216 /gene=\"PMP22\" /gene_synonym=\"...","source":"Homo sapiens (human)","symbol":"PMP22","synonym":"CIDP; CMT1A; CMT1E; DSS; GAS-3; GAS3; HMSNIA; HNPP; Sp110","version":"NM_153322.3"},{"aa_position":[],"accession":"NM_153321","definition":"Homo sapiens peripheral myelin protein 22 (PMP22), transcript variant 2, mRNA.","division":"RefSeq","geneid":"5376","gi":"","length":"1779","nt_position":[],"snippet":"MSIIVLHVAVLVLLFVSTIVSQWIVGNGHATDLWQNCSTSSSGNVHHCFSSSPNEWLQSVQATMILSIIFSILSLFLFFCQLFTLTKGGRFYITGIFQILAGLCVMSAAAIYTVRHPEWHLNSDYSYGFAYILAWVAFPLALLSGVIYVILRKRE\" misc_feature 159..617 /gene=\"PMP22\" /gene_synonym=\"CIDP; CMT1A; CMT1E; DSS; GAS-3; GAS3; HMSNIA; HNPP; Sp110\" /note=\"PMP-22/EMP/MP20/Claudin family; Region: PMP22_Claudin; pfam00822\" /db_xref=\"CDD:395662\" misc_feature 162..251 /gene=\"PMP22\" /gene_synonym=\"CIDP; CMT1A; CMT1E; DSS; GAS-3; GAS3; HMSNIA; HNPP; Sp110\" /note=\"propagated from UniProtKB/Swiss-Prot (Q01453.1); transmembrane region\" misc_feature 279..281 /gene=\"PMP22\" /gene_synonym...","source":"Homo sapiens (human)","symbol":"PMP22","synonym":"CIDP; CMT1A; CMT1E; DSS; GAS-3; GAS3; HMSNIA; HNPP; Sp110","version":"NM_153321.3"},{"aa_position":[],"accession":"NM_001281455","definition":"Homo sapiens peripheral myelin protein 22 (PMP22), transcript variant 4, mRNA.","division":"RefSeq","geneid":"5376","gi":"","length":"1783","nt_position":[],"snippet":"MSIIVLHVAVLVLLFVSTIVSQWIVGNGHATDLWQNCSTSSSGNVHHCFSSSPNEWLQSVQATMILSIIFSILSLFLFFCQLFTLTKGGRFYITGIFQILAGLCVMSAAAIYTVRHPEWHLNSDYSYGFAYILAWVAFPLALLSGVIYVILRKRE\" misc_feature 163..621 /gene=\"PMP22\" /gene_synonym=\"CIDP; CMT1A; CMT1E; DSS; GAS-3; GAS3; HMSNIA; HNPP; Sp110\" /note=\"PMP-22/EMP/MP20/Claudin family; Region: PMP22_Claudin; pfam00822\" /db_xref=\"CDD:395662\" misc_feature 166..255 /gene=\"PMP22\" /gene_synonym=\"CIDP; CMT1A; CMT1E; DSS; GAS-3; GAS3; HMSNIA; HNPP; Sp110\" /note=\"propagated from UniProtKB/Swiss-Prot (Q01453.1); transmembrane region\" misc_feature 283..285 /gene=\"PMP22\" /gene_synonym...","source":"Homo sapiens (human)","symbol":"PMP22","synonym":"CIDP; CMT1A; CMT1E; DSS; GAS-3; GAS3; HMSNIA; HNPP; Sp110","version":"NM_001281455.2"},{"aa_position":[],"accession":"NM_001281456","definition":"Homo sapiens peripheral myelin protein 22 (PMP22), transcript variant 5, mRNA.","division":"RefSeq","geneid":"5376","gi":"","length":"1824","nt_position":[],"snippet":"MSIIVLHVAVLVLLFVSTIVSQWIVGNGHATDLWQNCSTSSSGNVHHCFSSSPNEWLQSVQATMILSIIFSILSLFLFFCQLFTLTKGGRFYITGIFQILAGLCVMSAAAIYTVRHPEWHLNSDYSYGFAYILAWVAFPLALLSGVIYVILRKRE\" misc_feature 204..662 /gene=\"PMP22\" /gene_synonym=\"CIDP; CMT1A; CMT1E; DSS; GAS-3; GAS3; HMSNIA; HNPP; Sp110\" /note=\"PMP-22/EMP/MP20/Claudin family; Region: PMP22_Claudin; pfam00822\" /db_xref=\"CDD:395662\" misc_feature 207..296 /gene=\"PMP22\" /gene_synonym=\"CIDP; CMT1A; CMT1E; DSS; GAS-3; GAS3; HMSNIA; HNPP; Sp110\" /note=\"propagated from UniProtKB/Swiss-Prot (Q01453.1); transmembrane region\" misc_feature 324..326 /gene=\"PMP22\" /gene_synonym...","source":"Homo sapiens (human)","symbol":"PMP22","synonym":"CIDP; CMT1A; CMT1E; DSS; GAS-3; GAS3; HMSNIA; HNPP; Sp110","version":"NM_001281456.2"},{"aa_position":[],"accession":"NM_000304","definition":"Homo sapiens peripheral myelin protein 22 (PMP22), transcript variant 1, mRNA.","division":"RefSeq","geneid":"5376","gi":"","length":"1828","nt_position":[],"snippet":"MSIIVLHVAVLVLLFVSTIVSQWIVGNGHATDLWQNCSTSSSGNVHHCFSSSPNEWLQSVQATMILSIIFSILSLFLFFCQLFTLTKGGRFYITGIFQILAGLCVMSAAAIYTVRHPEWHLNSDYSYGFAYILAWVAFPLALLSGVIYVILRKRE\" misc_feature 208..666 /gene=\"PMP22\" /gene_synonym=\"CIDP; CMT1A; CMT1E; DSS; GAS-3; GAS3; HMSNIA; HNPP; Sp110\" /note=\"PMP-22/EMP/MP20/Claudin family; Region: PMP22_Claudin; pfam00822\" /db_xref=\"CDD:395662\" misc_feature 211..300 /gene=\"PMP22\" /gene_synonym=\"CIDP; CMT1A; CMT1E; DSS; GAS-3; GAS3; HMSNIA; HNPP; Sp110\" /note=\"propagated from UniProtKB/Swiss-Prot (Q01453.1); transmembrane region\" misc_feature 328..330 /gene=\"PMP22\" /gene_synonym...","source":"Homo sapiens (human)","symbol":"PMP22","synonym":"CIDP; CMT1A; CMT1E; DSS; GAS-3; GAS3; HMSNIA; HNPP; Sp110","version":"NM_000304.4"},{"aa_position":[],"accession":"NM_001385648","definition":"Homo sapiens UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8 (B3GNT8), transcript variant 1, mRNA.","division":"RefSeq","geneid":"374907","gi":"","length":"1543","nt_position":[],"snippet":"AUTHORS Perez,A.G., Andrade-Da-Costa,J., De Souza,W.F., De Souza Ferreira,M., Boroni,M., De Oliveira,I.M., Freire-Neto,C.A., Fernandes,P.V., De Lanna,C.A., Souza-Santos,P.T., Morgado-Diaz,J.A. and De-Freitas-Junior,J.C.M. TITLE N-glycosylation and receptor tyrosine kinase signaling affect claudin-3 levels in colorectal cancer cells JOURNAL Oncol Rep 44 (4), 1649-1661 (2020) PUBMED 32945502 REMARK GeneRIF: Nglycosylation and receptor tyrosine kinase signaling affect claudin3 levels in colorectal cancer cells. REFERENCE 3 (bases 1 to 1543) AUTHORS Shen,L., Dong,X., Wang,Y., Qiu,L., Peng,F. and...","source":"Homo sapiens (human)","symbol":"B3GNT8","synonym":"B3GALT7; beta3Gn-T8; BGALT15","version":"NM_001385648.2"},{"aa_position":[],"accession":"NM_001321346","definition":"Homo sapiens transmembrane protein 182 (TMEM182), transcript variant 5, mRNA.","division":"RefSeq","geneid":"130827","gi":"","length":"3210","nt_position":[],"snippet":"isoform d\" /protein_id=\"NP_001308275.2\" /db_xref=\"CCDS:CCDS92825.1\" /db_xref=\"GeneID:130827\" /db_xref=\"HGNC:HGNC:26391\" /translation=\"MRGEHNSTSYDSAVSILFSLVVMLYVIWVQAVADMESYRNMKMKDCLDFTPSVLYGWSFFLAPAGIFFSLLAGLLFLVVGWHIQIHH\" misc_feature <278..469 /gene=\"TMEM182\" /note=\"PMP-22/EMP/MP20/Claudin family; Region: PMP22_Claudin; cl21598\" /db_xref=\"CDD:473919\" variation 237..238 /gene=\"TMEM182\" /replace=\"\" /replace=\"tg\" /db_xref=\"dbSNP:2466715676\" variation 237 /gene=\"TMEM182\" /replace=\"c\" /replace=\"g\" /replace=\"t\" /db_xref=\"dbSNP:2466715660\" variation 238 /gene=\"TMEM182\" /replace=\"a\" /replace=\"g\" /...","source":"Homo sapiens (human)","symbol":"TMEM182","synonym":"","version":"NM_001321346.2"},{"aa_position":[],"accession":"NM_001271329","definition":"Homo sapiens MARVEL domain containing 3 (MARVELD3), transcript variant 3, mRNA.","division":"RefSeq","geneid":"91862","gi":"","length":"2054","nt_position":[],"snippet":"couples tight junctions to the MEKK1-JNK pathway to regulate cell behavior and survival. REFERENCE 4 (bases 1 to 2054) AUTHORS Cording,J., Berg,J., Kading,N., Bellmann,C., Tscheik,C., Westphal,J.K., Milatz,S., Gunzel,D., Wolburg,H., Piontek,J., Huber,O. and Blasig,I.E. TITLE In tight junctions, claudins regulate the interactions between occludin, tricellulin and marvelD3, which, inversely, modulate claudin oligomerization JOURNAL J Cell Sci 126 (Pt 2), 554-564 (2013) PUBMED 23203797 REFERENCE 5 (bases 1 to 2054) AUTHORS Timmann,C., Thye,T., Vens,M., Evans,J., May,J., Ehmen,C., Sievertsen,J.,...","source":"Homo sapiens (human)","symbol":"MARVELD3","synonym":"MARVD3; MRVLDC3","version":"NM_001271329.2"},{"aa_position":[],"accession":"NM_001363605","definition":"Homo sapiens transmembrane protein 225 (TMEM225), transcript variant 2, mRNA.","division":"RefSeq","geneid":"338661","gi":"","length":"991","nt_position":[],"snippet":"xref=\"dbSNP:745859884\" variation 245 /gene=\"TMEM225\" /gene_synonym=\"PMP22CD; PPP1R154; SPATA47\" /replace=\"a\" /replace=\"c\" /replace=\"t\" /db_xref=\"dbSNP:1863030109\" CDS 246..773 /gene=\"TMEM225\" /gene_synonym=\"PMP22CD; PPP1R154; SPATA47\" /note=\"isoform 2 is encoded by transcript variant 2; PMP22 claudin domain-containing protein; protein phosphatase 1, regulatory subunit 154; spermatogenesis associated 47\" /codon_start=1 /product=\"transmembrane protein 225 isoform 2\" /protein_id=\"NP_001350534.1\" /db_xref=\"GeneID:338661\" /db_xref=\"HGNC:HGNC:32390\" /translation=\"...","source":"Homo sapiens (human)","symbol":"TMEM225","synonym":"PMP22CD; PPP1R154; SPATA47","version":"NM_001363605.2"},{"aa_position":[],"accession":"NM_001321345","definition":"Homo sapiens transmembrane protein 182 (TMEM182), transcript variant 4, mRNA.","division":"RefSeq","geneid":"130827","gi":"","length":"3348","nt_position":[],"snippet":"db_xref=\"CCDS:CCDS82490.1\" /db_xref=\"GeneID:130827\" /db_xref=\"HGNC:HGNC:26391\" /translation=\"MRGEHNSTSYDSAVIYRGFWAVLMLLGVVAVVIASFLIICAAPFASHFLYKAGGGSYIAAGILFSLVVMLYVIWVQAVADMESYRNMKMKDCLDFTPSVLYGWSFFLAPAGIFFSLLAGLLFLVVGWHIQIHH\" misc_feature <236..607 /gene=\"TMEM182\" /note=\"PMP-22/EMP/MP20/Claudin family; Region: PMP22_Claudin; cl21598\" /db_xref=\"CDD:473919\" variation 237..238 /gene=\"TMEM182\" /replace=\"\" /replace=\"tg\" /db_xref=\"dbSNP:2466715676\" variation 237 /gene=\"TMEM182\" /replace=\"c\" /replace=\"g\" /replace=\"t\" /db_xref=\"dbSNP:2466715660\" variation 238 /gene=\"TMEM182\" /replace=\"a\" /replace=\"g...","source":"Homo sapiens (human)","symbol":"TMEM182","synonym":"","version":"NM_001321345.2"},{"aa_position":[],"accession":"XM_017028531","definition":"PREDICTED: Homo sapiens calcium voltage-gated channel auxiliary subunit gamma 2 (CACNG2), transcript variant X1, mRNA.","division":"RefSeq","geneid":"10369","gi":"","length":"4320","nt_position":[],"snippet":"misc_feature <152..445 /gene=\"CACNG2\" /gene_synonym=\"MRD10\" /note=\"PMP-22/EMP/MP20/Claudin family; Region: PMP22_Claudin; cl21598\" /db_xref=\"CDD:473919\" variation 113 /gene=\"CACNG2\" /gene_synonym=\"MRD10\" /replace=\"a\" /replace=\"g\" /db_xref=\"dbSNP:1023530496\" variation 114 /gene=\"CACNG2\" /gene_synonym=\"MRD10\" /replace=\"a\" /replace=\"c\" /replace=\"g\" /replace=\"t\" /db_xref=\"dbSNP:543217939\" variation 116 /gene=\"CACNG2\" /gene_synonym=\"MRD10\" /replace=\"a\" /replace=\"g\" /db_xref=\"dbSNP:1935199692\" variation 117 /gene=\"CACNG2\" /gene_synonym=\"MRD10\" /replace=\"a\" /replace=\"g\" /db_xref=\"dbSNP:183960906\"...","source":"Homo sapiens (human)","symbol":"CACNG2","synonym":"MRD10","version":"XM_017028531.3"},{"aa_position":[],"accession":"NM_001321344","definition":"Homo sapiens transmembrane protein 182 (TMEM182), transcript variant 3, mRNA.","division":"RefSeq","geneid":"130827","gi":"","length":"3433","nt_position":[],"snippet":"db_xref=\"HGNC:HGNC:26391\" /translation=\"MIENVTFHHEGFFWRCWFNGIVEENDSNIWKFWYTNQPPSKNCTHAYLSPYPFMRGEHNSTSYDSAVIYRGFWAVLMLLGVVAVVIASFLIICAAPFASHFLYKAGGGSYIAAGILFSLVVMLYVIWVQAVADMESYRNMKMKDCLDFTPSVLYGWSFFLAPAGIFFSLLAGLLFLVVGWHIQIHH\" misc_feature 165..692 /gene=\"TMEM182\" /note=\"PMP-22/EMP/MP20/Claudin tight junction; Region: Claudin_2; pfam13903\" /db_xref=\"CDD:372799\" variation 162 /gene=\"TMEM182\" /replace=\"a\" /replace=\"g\" /replace=\"t\" /db_xref=\"dbSNP:1341844888\" exon 165..264 /gene=\"TMEM182\" /inference=\"alignment:Splign:2.1.0\" variation 165 /gene=\"TMEM182\" /replace=\"a\" /replace=\"g\" /db_xref=\"dbSNP...","source":"Homo sapiens (human)","symbol":"TMEM182","synonym":"","version":"NM_001321344.2"},{"aa_position":[],"accession":"XM_047436306","definition":"PREDICTED: Homo sapiens peripheral myelin protein 22 (PMP22), transcript variant X1, mRNA.","division":"RefSeq","geneid":"5376","gi":"","length":"3312","nt_position":[],"snippet":"db_xref=\"MIM:601097\" /translation=\"MSIIVLHVAVLVLLFVSTIVSQWIVGNGHATDLWQNCSTSSSGNVHHCFSSSPNEWLQSVQATMILSIIFSILSLFLFFCQLFTLTKGGRFYITGIFQILAALPSLDKSDRAQETTSVFLKDKS\" misc_feature 222..>491 /gene=\"PMP22\" /gene_synonym=\"CIDP; CMT1A; CMT1E; DSS; GAS-3; GAS3; HMSNIA; HNPP; Sp110\" /note=\"PMP-22/EMP/MP20/Claudin family; Region: PMP22_Claudin; cl21598\" /db_xref=\"CDD:473919\" variation 164 /gene=\"PMP22\" /gene_synonym=\"CIDP; CMT1A; CMT1E; DSS; GAS-3; GAS3; HMSNIA; HNPP; Sp110\" /replace=\"c\" /replace=\"t\" /db_xref=\"dbSNP:1474281036\" variation 165 /gene=\"PMP22\" /gene_synonym=\"CIDP; CMT1A; CMT1E; DSS; GAS-3;...","source":"Homo sapiens (human)","symbol":"PMP22","synonym":"CIDP; CMT1A; CMT1E; DSS; GAS-3; GAS3; HMSNIA; HNPP; Sp110","version":"XM_047436306.1"},{"aa_position":[],"accession":"NM_001321343","definition":"Homo sapiens transmembrane protein 182 (TMEM182), transcript variant 2, mRNA.","division":"RefSeq","geneid":"130827","gi":"","length":"3560","nt_position":[],"snippet":"db_xref=\"HGNC:HGNC:26391\" /translation=\"MIENVTFHHEGFFWRCWFNGIVEENDSNIWKFWYTNQPPSKNCTHAYLSPYPFMRGEHNSTSYDSAVIYRGFWAVLMLLGVVAVVIASFLIICAAPFASHFLYKAGGGSYIAAGILFSLVVMLYVIWVQAVADMESYRNMKMKDCLDFTPSVLYGWSFFLAPAGIFFSLLAGLLFLVVGWHIQIHH\" misc_feature 292..819 /gene=\"TMEM182\" /note=\"PMP-22/EMP/MP20/Claudin tight junction; Region: Claudin_2; pfam13903\" /db_xref=\"CDD:372799\" variation 289 /gene=\"TMEM182\" /replace=\"a\" /replace=\"g\" /replace=\"t\" /db_xref=\"dbSNP:1341844888\" exon 292..391 /gene=\"TMEM182\" /inference=\"alignment:Splign:2.1.0\" variation 292 /gene=\"TMEM182\" /replace=\"a\" /replace=\"g\" /db_xref=\"dbSNP...","source":"Homo sapiens (human)","symbol":"TMEM182","synonym":"","version":"NM_001321343.2"},{"aa_position":[],"accession":"NM_198540","definition":"Homo sapiens UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8 (B3GNT8), transcript variant 2, mRNA.","division":"RefSeq","geneid":"374907","gi":"","length":"1894","nt_position":[],"snippet":"AUTHORS Perez,A.G., Andrade-Da-Costa,J., De Souza,W.F., De Souza Ferreira,M., Boroni,M., De Oliveira,I.M., Freire-Neto,C.A., Fernandes,P.V., De Lanna,C.A., Souza-Santos,P.T., Morgado-Diaz,J.A. and De-Freitas-Junior,J.C.M. TITLE N-glycosylation and receptor tyrosine kinase signaling affect claudin-3 levels in colorectal cancer cells JOURNAL Oncol Rep 44 (4), 1649-1661 (2020) PUBMED 32945502 REMARK GeneRIF: Nglycosylation and receptor tyrosine kinase signaling affect claudin3 levels in colorectal cancer cells. REFERENCE 3 (bases 1 to 1894) AUTHORS Shen,L., Dong,X., Wang,Y., Qiu,L., Peng,F. and...","source":"Homo sapiens (human)","symbol":"B3GNT8","synonym":"B3GALT7; beta3Gn-T8; BGALT15","version":"NM_198540.2"},{"aa_position":[],"accession":"NM_001017967","definition":"Homo sapiens MARVEL domain containing 3 (MARVELD3), transcript variant 1, mRNA.","division":"RefSeq","geneid":"91862","gi":"","length":"2217","nt_position":[],"snippet":"couples tight junctions to the MEKK1-JNK pathway to regulate cell behavior and survival. REFERENCE 4 (bases 1 to 2217) AUTHORS Cording,J., Berg,J., Kading,N., Bellmann,C., Tscheik,C., Westphal,J.K., Milatz,S., Gunzel,D., Wolburg,H., Piontek,J., Huber,O. and Blasig,I.E. TITLE In tight junctions, claudins regulate the interactions between occludin, tricellulin and marvelD3, which, inversely, modulate claudin oligomerization JOURNAL J Cell Sci 126 (Pt 2), 554-564 (2013) PUBMED 23203797 REFERENCE 5 (bases 1 to 2217) AUTHORS Timmann,C., Thye,T., Vens,M., Evans,J., May,J., Ehmen,C., Sievertsen,J.,...","source":"Homo sapiens (human)","symbol":"MARVELD3","synonym":"MARVD3; MRVLDC3","version":"NM_001017967.4"},{"aa_position":[],"accession":"NM_144632","definition":"Homo sapiens transmembrane protein 182 (TMEM182), transcript variant 1, mRNA.","division":"RefSeq","geneid":"130827","gi":"","length":"3588","nt_position":[],"snippet":"sig_peptide 188..265 /gene=\"TMEM182\" /note=\"/evidence=ECO:0000255; propagated from UniProtKB/Swiss-Prot (Q6ZP80.2)\" misc_feature 230..847 /gene=\"TMEM182\" /note=\"PMP-22/EMP/MP20/Claudin tight junction; Region: Claudin_2; pfam13903\" /db_xref=\"CDD:372799\" mat_peptide 266..874 /gene=\"TMEM182\" /product=\"Transmembrane protein 182. /id=PRO_0000290226\" /note=\"propagated from UniProtKB/Swiss-Prot (Q6ZP80.2)\" misc_feature 326..328 /gene=\"TMEM182\" /note=\"N-linked (GlcNAc...) asparagine. /evidence=ECO:0000255; propagated from UniProtKB/Swiss-Prot (Q6ZP80.2); glycosylation site\" misc_feature 332..364 /gene...","source":"Homo sapiens (human)","symbol":"TMEM182","synonym":"","version":"NM_144632.5"},{"aa_position":[],"accession":"NM_001013743","definition":"Homo sapiens transmembrane protein 225 (TMEM225), transcript variant 1, mRNA.","division":"RefSeq","geneid":"338661","gi":"","length":"1141","nt_position":[],"snippet":"xref=\"dbSNP:745859884\" variation 245 /gene=\"TMEM225\" /gene_synonym=\"PMP22CD; PPP1R154; SPATA47\" /replace=\"a\" /replace=\"c\" /replace=\"t\" /db_xref=\"dbSNP:1863030109\" CDS 246..923 /gene=\"TMEM225\" /gene_synonym=\"PMP22CD; PPP1R154; SPATA47\" /note=\"isoform 1 is encoded by transcript variant 1; PMP22 claudin domain-containing protein; protein phosphatase 1, regulatory subunit 154; spermatogenesis associated 47\" /codon_start=1 /product=\"transmembrane protein 225 isoform 1\" /protein_id=\"NP_001013765.2\" /db_xref=\"CCDS:CCDS31697.1\" /db_xref=\"GeneID:338661\" /db_xref=\"HGNC:HGNC:32390\" /translation=\"...","source":"Homo sapiens (human)","symbol":"TMEM225","synonym":"PMP22CD; PPP1R154; SPATA47","version":"NM_001013743.3"},{"aa_position":[],"accession":"NR_168054","definition":"Homo sapiens ubiquitin specific peptidase 40 (USP40), transcript variant 17, non-coding RNA.","division":"RefSeq","geneid":"55230","gi":"","length":"5516","nt_position":[],"snippet":"feedback loop. REFERENCE 2 (bases 1 to 5516) AUTHORS Wu,Q., Qiu,Y., Guo,J., Yuan,Z., Yang,Y., Zhu,Q., Zhang,Z., Guo,J., Wu,Y., Zhang,J., Huang,D., Tu,K. and Hu,X. TITLE USP40 promotes hepatocellular carcinoma cell proliferation, migration and stemness by deubiquitinating and stabilizing Claudin1 JOURNAL Biol Direct 19 (1), 13 (2024) PUBMED 38308285 REMARK GeneRIF: USP40 promotes hepatocellular carcinoma cell proliferation, migration and stemness by deubiquitinating and stabilizing Claudin1. Publication Status: Online-Only REFERENCE 3 (bases 1 to 5516) AUTHORS Miao,J., Li,L., Shaheen,N., Wei,J...","source":"Homo sapiens (human)","symbol":"USP40","synonym":"","version":"NR_168054.1"},{"aa_position":[],"accession":"NM_001382295","definition":"Homo sapiens ubiquitin specific peptidase 40 (USP40), transcript variant 3, mRNA.","division":"RefSeq","geneid":"55230","gi":"","length":"5690","nt_position":[],"snippet":"feedback loop. REFERENCE 2 (bases 1 to 5690) AUTHORS Wu,Q., Qiu,Y., Guo,J., Yuan,Z., Yang,Y., Zhu,Q., Zhang,Z., Guo,J., Wu,Y., Zhang,J., Huang,D., Tu,K. and Hu,X. TITLE USP40 promotes hepatocellular carcinoma cell proliferation, migration and stemness by deubiquitinating and stabilizing Claudin1 JOURNAL Biol Direct 19 (1), 13 (2024) PUBMED 38308285 REMARK GeneRIF: USP40 promotes hepatocellular carcinoma cell proliferation, migration and stemness by deubiquitinating and stabilizing Claudin1. Publication Status: Online-Only REFERENCE 3 (bases 1 to 5690) AUTHORS Miao,J., Li,L., Shaheen,N., Wei,J...","source":"Homo sapiens (human)","symbol":"USP40","synonym":"","version":"NM_001382295.1"},{"aa_position":[],"accession":"NM_018218","definition":"Homo sapiens ubiquitin specific peptidase 40 (USP40), transcript variant 2, mRNA.","division":"RefSeq","geneid":"55230","gi":"","length":"5692","nt_position":[],"snippet":"feedback loop. REFERENCE 2 (bases 1 to 5692) AUTHORS Wu,Q., Qiu,Y., Guo,J., Yuan,Z., Yang,Y., Zhu,Q., Zhang,Z., Guo,J., Wu,Y., Zhang,J., Huang,D., Tu,K. and Hu,X. TITLE USP40 promotes hepatocellular carcinoma cell proliferation, migration and stemness by deubiquitinating and stabilizing Claudin1 JOURNAL Biol Direct 19 (1), 13 (2024) PUBMED 38308285 REMARK GeneRIF: USP40 promotes hepatocellular carcinoma cell proliferation, migration and stemness by deubiquitinating and stabilizing Claudin1. Publication Status: Online-Only REFERENCE 3 (bases 1 to 5692) AUTHORS Miao,J., Li,L., Shaheen,N., Wei,J...","source":"Homo sapiens (human)","symbol":"USP40","synonym":"","version":"NM_018218.4"},{"aa_position":[],"accession":"NM_001365479","definition":"Homo sapiens ubiquitin specific peptidase 40 (USP40), transcript variant 1, mRNA.","division":"RefSeq","geneid":"55230","gi":"","length":"5695","nt_position":[],"snippet":"feedback loop. REFERENCE 2 (bases 1 to 5695) AUTHORS Wu,Q., Qiu,Y., Guo,J., Yuan,Z., Yang,Y., Zhu,Q., Zhang,Z., Guo,J., Wu,Y., Zhang,J., Huang,D., Tu,K. and Hu,X. TITLE USP40 promotes hepatocellular carcinoma cell proliferation, migration and stemness by deubiquitinating and stabilizing Claudin1 JOURNAL Biol Direct 19 (1), 13 (2024) PUBMED 38308285 REMARK GeneRIF: USP40 promotes hepatocellular carcinoma cell proliferation, migration and stemness by deubiquitinating and stabilizing Claudin1. Publication Status: Online-Only REFERENCE 3 (bases 1 to 5695) AUTHORS Miao,J., Li,L., Shaheen,N., Wei,J...","source":"Homo sapiens (human)","symbol":"USP40","synonym":"","version":"NM_001365479.2"},{"aa_position":[],"accession":"NM_001382298","definition":"Homo sapiens ubiquitin specific peptidase 40 (USP40), transcript variant 6, mRNA.","division":"RefSeq","geneid":"55230","gi":"","length":"5759","nt_position":[],"snippet":"feedback loop. REFERENCE 2 (bases 1 to 5759) AUTHORS Wu,Q., Qiu,Y., Guo,J., Yuan,Z., Yang,Y., Zhu,Q., Zhang,Z., Guo,J., Wu,Y., Zhang,J., Huang,D., Tu,K. and Hu,X. TITLE USP40 promotes hepatocellular carcinoma cell proliferation, migration and stemness by deubiquitinating and stabilizing Claudin1 JOURNAL Biol Direct 19 (1), 13 (2024) PUBMED 38308285 REMARK GeneRIF: USP40 promotes hepatocellular carcinoma cell proliferation, migration and stemness by deubiquitinating and stabilizing Claudin1. Publication Status: Online-Only REFERENCE 3 (bases 1 to 5759) AUTHORS Miao,J., Li,L., Shaheen,N., Wei,J...","source":"Homo sapiens (human)","symbol":"USP40","synonym":"","version":"NM_001382298.1"},{"aa_position":[],"accession":"NM_001382296","definition":"Homo sapiens ubiquitin specific peptidase 40 (USP40), transcript variant 4, mRNA.","division":"RefSeq","geneid":"55230","gi":"","length":"5755","nt_position":[],"snippet":"feedback loop. REFERENCE 2 (bases 1 to 5755) AUTHORS Wu,Q., Qiu,Y., Guo,J., Yuan,Z., Yang,Y., Zhu,Q., Zhang,Z., Guo,J., Wu,Y., Zhang,J., Huang,D., Tu,K. and Hu,X. TITLE USP40 promotes hepatocellular carcinoma cell proliferation, migration and stemness by deubiquitinating and stabilizing Claudin1 JOURNAL Biol Direct 19 (1), 13 (2024) PUBMED 38308285 REMARK GeneRIF: USP40 promotes hepatocellular carcinoma cell proliferation, migration and stemness by deubiquitinating and stabilizing Claudin1. Publication Status: Online-Only REFERENCE 3 (bases 1 to 5755) AUTHORS Miao,J., Li,L., Shaheen,N., Wei,J...","source":"Homo sapiens (human)","symbol":"USP40","synonym":"","version":"NM_001382296.1"},{"aa_position":[],"accession":"NR_168049","definition":"Homo sapiens ubiquitin specific peptidase 40 (USP40), transcript variant 12, non-coding RNA.","division":"RefSeq","geneid":"55230","gi":"","length":"5803","nt_position":[],"snippet":"feedback loop. REFERENCE 2 (bases 1 to 5803) AUTHORS Wu,Q., Qiu,Y., Guo,J., Yuan,Z., Yang,Y., Zhu,Q., Zhang,Z., Guo,J., Wu,Y., Zhang,J., Huang,D., Tu,K. and Hu,X. TITLE USP40 promotes hepatocellular carcinoma cell proliferation, migration and stemness by deubiquitinating and stabilizing Claudin1 JOURNAL Biol Direct 19 (1), 13 (2024) PUBMED 38308285 REMARK GeneRIF: USP40 promotes hepatocellular carcinoma cell proliferation, migration and stemness by deubiquitinating and stabilizing Claudin1. Publication Status: Online-Only REFERENCE 3 (bases 1 to 5803) AUTHORS Miao,J., Li,L., Shaheen,N., Wei,J...","source":"Homo sapiens (human)","symbol":"USP40","synonym":"","version":"NR_168049.1"},{"aa_position":[],"accession":"NR_168052","definition":"Homo sapiens ubiquitin specific peptidase 40 (USP40), transcript variant 15, non-coding RNA.","division":"RefSeq","geneid":"55230","gi":"","length":"5833","nt_position":[],"snippet":"feedback loop. REFERENCE 2 (bases 1 to 5833) AUTHORS Wu,Q., Qiu,Y., Guo,J., Yuan,Z., Yang,Y., Zhu,Q., Zhang,Z., Guo,J., Wu,Y., Zhang,J., Huang,D., Tu,K. and Hu,X. TITLE USP40 promotes hepatocellular carcinoma cell proliferation, migration and stemness by deubiquitinating and stabilizing Claudin1 JOURNAL Biol Direct 19 (1), 13 (2024) PUBMED 38308285 REMARK GeneRIF: USP40 promotes hepatocellular carcinoma cell proliferation, migration and stemness by deubiquitinating and stabilizing Claudin1. Publication Status: Online-Only REFERENCE 3 (bases 1 to 5833) AUTHORS Miao,J., Li,L., Shaheen,N., Wei,J...","source":"Homo sapiens (human)","symbol":"USP40","synonym":"","version":"NR_168052.1"},{"aa_position":[],"accession":"NR_168053","definition":"Homo sapiens ubiquitin specific peptidase 40 (USP40), transcript variant 16, non-coding RNA.","division":"RefSeq","geneid":"55230","gi":"","length":"5842","nt_position":[],"snippet":"feedback loop. REFERENCE 2 (bases 1 to 5842) AUTHORS Wu,Q., Qiu,Y., Guo,J., Yuan,Z., Yang,Y., Zhu,Q., Zhang,Z., Guo,J., Wu,Y., Zhang,J., Huang,D., Tu,K. and Hu,X. TITLE USP40 promotes hepatocellular carcinoma cell proliferation, migration and stemness by deubiquitinating and stabilizing Claudin1 JOURNAL Biol Direct 19 (1), 13 (2024) PUBMED 38308285 REMARK GeneRIF: USP40 promotes hepatocellular carcinoma cell proliferation, migration and stemness by deubiquitinating and stabilizing Claudin1. Publication Status: Online-Only REFERENCE 3 (bases 1 to 5842) AUTHORS Miao,J., Li,L., Shaheen,N., Wei,J...","source":"Homo sapiens (human)","symbol":"USP40","synonym":"","version":"NR_168053.1"},{"aa_position":[],"accession":"NM_052858","definition":"Homo sapiens MARVEL domain containing 3 (MARVELD3), transcript variant 2, mRNA.","division":"RefSeq","geneid":"91862","gi":"","length":"2914","nt_position":[],"snippet":"couples tight junctions to the MEKK1-JNK pathway to regulate cell behavior and survival. REFERENCE 4 (bases 1 to 2914) AUTHORS Cording,J., Berg,J., Kading,N., Bellmann,C., Tscheik,C., Westphal,J.K., Milatz,S., Gunzel,D., Wolburg,H., Piontek,J., Huber,O. and Blasig,I.E. TITLE In tight junctions, claudins regulate the interactions between occludin, tricellulin and marvelD3, which, inversely, modulate claudin oligomerization JOURNAL J Cell Sci 126 (Pt 2), 554-564 (2013) PUBMED 23203797 REFERENCE 5 (bases 1 to 2914) AUTHORS Timmann,C., Thye,T., Vens,M., Evans,J., May,J., Ehmen,C., Sievertsen,J.,...","source":"Homo sapiens (human)","symbol":"MARVELD3","synonym":"MARVD3; MRVLDC3","version":"NM_052858.6"},{"aa_position":[],"accession":"NM_001006625","definition":"Homo sapiens podoplanin (PDPN), transcript variant 4, mRNA.","division":"RefSeq","geneid":"10630","gi":"","length":"2642","nt_position":[],"snippet":"PUBMED 37658727 REMARK GeneRIF: Podoplanin-positive cells located in the basal layer of Bowen disease include tumor cells with cancer stem cell properties. REFERENCE 5 (bases 1 to 2642) AUTHORS Kabra,H., Mohanty,N.R., Tripathy,S., Mohanty,M., Senapati,U. and Rath,J. TITLE Expression of Claudin-4 and D2-40 and their significance in prostatic adenocarcinoma JOURNAL J Cancer Res Ther 19 (Suppl 2), S800-S806 (2023) PUBMED 38384059 REMARK GeneRIF: Expression of Claudin-4 and D2-40 and their significance in prostatic adenocarcinoma. REFERENCE 6 (bases 1 to 2642) AUTHORS Kato,Y., Fujita,N., Kunita,A...","source":"Homo sapiens (human)","symbol":"PDPN","synonym":"AGGRUS; D2-40; GP36; Gp38; GP40; HT1A-1; OTS8; PA2.26; T1A; T1A-2; T1A2; TI1A","version":"NM_001006625.2"},{"aa_position":[],"accession":"NM_001006624","definition":"Homo sapiens podoplanin (PDPN), transcript variant 3, mRNA.","division":"RefSeq","geneid":"10630","gi":"","length":"2648","nt_position":[],"snippet":"PUBMED 37658727 REMARK GeneRIF: Podoplanin-positive cells located in the basal layer of Bowen disease include tumor cells with cancer stem cell properties. REFERENCE 5 (bases 1 to 2648) AUTHORS Kabra,H., Mohanty,N.R., Tripathy,S., Mohanty,M., Senapati,U. and Rath,J. TITLE Expression of Claudin-4 and D2-40 and their significance in prostatic adenocarcinoma JOURNAL J Cancer Res Ther 19 (Suppl 2), S800-S806 (2023) PUBMED 38384059 REMARK GeneRIF: Expression of Claudin-4 and D2-40 and their significance in prostatic adenocarcinoma. REFERENCE 6 (bases 1 to 2648) AUTHORS Kato,Y., Fujita,N., Kunita,A...","source":"Homo sapiens (human)","symbol":"PDPN","synonym":"AGGRUS; D2-40; GP36; Gp38; GP40; HT1A-1; OTS8; PA2.26; T1A; T1A-2; T1A2; TI1A","version":"NM_001006624.2"},{"aa_position":[],"accession":"NM_001385053","definition":"Homo sapiens podoplanin (PDPN), transcript variant 5, mRNA.","division":"RefSeq","geneid":"10630","gi":"","length":"2717","nt_position":[],"snippet":"PUBMED 37658727 REMARK GeneRIF: Podoplanin-positive cells located in the basal layer of Bowen disease include tumor cells with cancer stem cell properties. REFERENCE 5 (bases 1 to 2717) AUTHORS Kabra,H., Mohanty,N.R., Tripathy,S., Mohanty,M., Senapati,U. and Rath,J. TITLE Expression of Claudin-4 and D2-40 and their significance in prostatic adenocarcinoma JOURNAL J Cancer Res Ther 19 (Suppl 2), S800-S806 (2023) PUBMED 38384059 REMARK GeneRIF: Expression of Claudin-4 and D2-40 and their significance in prostatic adenocarcinoma. REFERENCE 6 (bases 1 to 2717) AUTHORS Kato,Y., Fujita,N., Kunita,A...","source":"Homo sapiens (human)","symbol":"PDPN","synonym":"AGGRUS; D2-40; GP36; Gp38; GP40; HT1A-1; OTS8; PA2.26; T1A; T1A-2; T1A2; TI1A","version":"NM_001385053.1"},{"aa_position":[],"accession":"NM_006474","definition":"Homo sapiens podoplanin (PDPN), transcript variant 1, mRNA.","division":"RefSeq","geneid":"10630","gi":"","length":"2737","nt_position":[],"snippet":"PUBMED 37658727 REMARK GeneRIF: Podoplanin-positive cells located in the basal layer of Bowen disease include tumor cells with cancer stem cell properties. REFERENCE 5 (bases 1 to 2737) AUTHORS Kabra,H., Mohanty,N.R., Tripathy,S., Mohanty,M., Senapati,U. and Rath,J. TITLE Expression of Claudin-4 and D2-40 and their significance in prostatic adenocarcinoma JOURNAL J Cancer Res Ther 19 (Suppl 2), S800-S806 (2023) PUBMED 38384059 REMARK GeneRIF: Expression of Claudin-4 and D2-40 and their significance in prostatic adenocarcinoma. REFERENCE 6 (bases 1 to 2737) AUTHORS Kato,Y., Fujita,N., Kunita,A...","source":"Homo sapiens (human)","symbol":"PDPN","synonym":"AGGRUS; D2-40; GP36; Gp38; GP40; HT1A-1; OTS8; PA2.26; T1A; T1A-2; T1A2; TI1A","version":"NM_006474.5"},{"aa_position":[],"accession":"NM_198389","definition":"Homo sapiens podoplanin (PDPN), transcript variant 2, mRNA.","division":"RefSeq","geneid":"10630","gi":"","length":"2822","nt_position":[],"snippet":"PUBMED 37658727 REMARK GeneRIF: Podoplanin-positive cells located in the basal layer of Bowen disease include tumor cells with cancer stem cell properties. REFERENCE 5 (bases 1 to 2822) AUTHORS Kabra,H., Mohanty,N.R., Tripathy,S., Mohanty,M., Senapati,U. and Rath,J. TITLE Expression of Claudin-4 and D2-40 and their significance in prostatic adenocarcinoma JOURNAL J Cancer Res Ther 19 (Suppl 2), S800-S806 (2023) PUBMED 38384059 REMARK GeneRIF: Expression of Claudin-4 and D2-40 and their significance in prostatic adenocarcinoma. REFERENCE 6 (bases 1 to 2822) AUTHORS Kato,Y., Fujita,N., Kunita,A...","source":"Homo sapiens (human)","symbol":"PDPN","synonym":"AGGRUS; D2-40; GP36; Gp38; GP40; HT1A-1; OTS8; PA2.26; T1A; T1A-2; T1A2; TI1A","version":"NM_198389.2"},{"aa_position":[],"accession":"NM_001205254","definition":"Homo sapiens occludin (OCLN), transcript variant 2, mRNA.","division":"RefSeq","geneid":"100506658","gi":"","length":"6181","nt_position":[],"snippet":"is overexpressed in tubo-ovarian high-grade serous carcinoma compared to mesothelioma and is a marker of tumor progression and chemoresistance. REFERENCE 3 (bases 1 to 6181) AUTHORS So,C.W., Sourisseau,M., Sarwar,S., Evans,M.J. and Randall,G. TITLE Roles of epidermal growth factor receptor, claudin-1 and occludin in multi-step entry of hepatitis C virus into polarized hepatoma spheroids JOURNAL PLoS Pathog 19 (12), e1011887 (2023) PUBMED 38157366 REMARK GeneRIF: Roles of epidermal growth factor receptor, claudin-1 and occludin in multi-step entry of hepatitis C virus into polarized hepatoma...","source":"Homo sapiens (human)","symbol":"OCLN","synonym":"BLCPMG; PPP1R115; PTORCH1","version":"NM_001205254.2"},{"aa_position":[],"accession":"NM_002538","definition":"Homo sapiens occludin (OCLN), transcript variant 1, mRNA.","division":"RefSeq","geneid":"100506658","gi":"","length":"6183","nt_position":[],"snippet":"is overexpressed in tubo-ovarian high-grade serous carcinoma compared to mesothelioma and is a marker of tumor progression and chemoresistance. REFERENCE 3 (bases 1 to 6183) AUTHORS So,C.W., Sourisseau,M., Sarwar,S., Evans,M.J. and Randall,G. TITLE Roles of epidermal growth factor receptor, claudin-1 and occludin in multi-step entry of hepatitis C virus into polarized hepatoma spheroids JOURNAL PLoS Pathog 19 (12), e1011887 (2023) PUBMED 38157366 REMARK GeneRIF: Roles of epidermal growth factor receptor, claudin-1 and occludin in multi-step entry of hepatitis C virus into polarized hepatoma...","source":"Homo sapiens (human)","symbol":"OCLN","synonym":"BLCPMG; PPP1R115; PTORCH1","version":"NM_002538.4"},{"aa_position":[],"accession":"NM_031895","definition":"Homo sapiens calcium voltage-gated channel auxiliary subunit gamma 8 (CACNG8), mRNA.","division":"RefSeq","geneid":"59283","gi":"","length":"8850","nt_position":[],"snippet":"misc_feature 255..875 /gene=\"CACNG8\" /note=\"PMP-22/EMP/MP20/Claudin family; Region: PMP22_Claudin; cl21598\" /db_xref=\"CDD:473919\" misc_feature 261..323 /gene=\"CACNG8\" /note=\"propagated from UniProtKB/Swiss-Prot (Q8WXS5.3); transmembrane region\" misc_feature 591..653 /gene=\"CACNG8\" /note=\"propagated from UniProtKB/Swiss-Prot (Q8WXS5.3); transmembrane region\" misc_feature 678..740 /gene=\"CACNG8\" /note=\"propagated from UniProtKB/Swiss-Prot (Q8WXS5.3); transmembrane region\" misc_feature 828..890 /gene=\"CACNG8\" /note=\"propagated from UniProtKB/Swiss-Prot (Q8WXS5.3); transmembrane region\" misc_...","source":"Homo sapiens (human)","symbol":"CACNG8","synonym":"","version":"NM_031895.6"},{"aa_position":[],"accession":"NM_022121","definition":"Homo sapiens p53 apoptosis effector related to PMP22 (PERP), mRNA.","division":"RefSeq","geneid":"64065","gi":"","length":"4198","nt_position":[],"snippet":"gene=\"PERP\" /gene_synonym=\"dJ496H19.1; EKVP7; KCP1; KRTCAP1; OLMS2; PIGPC1; THW\" /note=\"propagated from UniProtKB/Swiss-Prot (Q96FX8.1); transmembrane region\" misc_feature 128..571 /gene=\"PERP\" /gene_synonym=\"dJ496H19.1; EKVP7; KCP1; KRTCAP1; OLMS2; PIGPC1; THW\" /note=\"PMP-22/EMP/MP20/Claudin family; Region: PMP22_Claudin; cl21598\" /db_xref=\"CDD:473919\" misc_feature 314..376 /gene=\"PERP\" /gene_synonym=\"dJ496H19.1; EKVP7; KCP1; KRTCAP1; OLMS2; PIGPC1; THW\" /note=\"propagated from UniProtKB/Swiss-Prot (Q96FX8.1); transmembrane region\" misc_feature 407..469 /gene=\"PERP\" /gene_synonym=\"dJ496H19.1;...","source":"Homo sapiens (human)","symbol":"PERP","synonym":"dJ496H19.1; EKVP7; KCP1; KRTCAP1; OLMS2; PIGPC1; THW","version":"NM_022121.5"},{"aa_position":[],"accession":"NM_001423","definition":"Homo sapiens epithelial membrane protein 1 (EMP1), mRNA.","division":"RefSeq","geneid":"2012","gi":"","length":"5913","nt_position":[],"snippet":"db_xref=\"MIM:602333\" /translation=\"MLVLLAGIFVVHIATVIMLFVSTIANVWLVSNTVDASVGLWKNCTNISCSDSLSYASEDALKTVQAFMILSIIFCVIALLVFVFQLFTMEKGNRFFLSGATTLVCWLCILVGVSIYTSHYANRDGTQYHHGYSYILGWICFCFSFIIGVLYLVLRKK\" misc_feature 190..642 /gene=\"EMP1\" /gene_synonym=\"CL-20; EMP-1; TMP\" /note=\"PMP-22/EMP/MP20/Claudin family; Region: PMP22_Claudin; pfam00822\" /db_xref=\"CDD:395662\" misc_feature 190..252 /gene=\"EMP1\" /gene_synonym=\"CL-20; EMP-1; TMP\" /note=\"propagated from UniProtKB/Swiss-Prot (P54849.3); transmembrane region\" misc_feature 316..318 /gene=\"EMP1\" /gene_synonym=\"CL-20; EMP-1; TMP\" /note=\"N-linked...","source":"Homo sapiens (human)","symbol":"EMP1","synonym":"CL-20; EMP-1; TMP","version":"NM_001423.3"},{"aa_position":[],"accession":"NM_001424","definition":"Homo sapiens epithelial membrane protein 2 (EMP2), mRNA.","division":"RefSeq","geneid":"2013","gi":"","length":"5097","nt_position":[],"snippet":"HGNC:3334\" /db_xref=\"MIM:602334\" /translation=\"MLVLLAFIIAFHITSAALLFIATVDNAWWVGDEFFADVWRICTNNTNCTVINDSFQEYSTLQAVQATMILSTILCCIAFFIFVLQLFRLKQGERFVLTSIIQLMSCLCVMIAASIYTDRREDIHDKNAKFYPVTREGSYGYSYILAWVAFACTFISGMMYLILRKRK\" misc_feature 111..590 /gene=\"EMP2\" /gene_synonym=\"XMP\" /note=\"PMP-22/EMP/MP20/Claudin family; Region: PMP22_Claudin; pfam00822\" /db_xref=\"CDD:395662\" misc_feature 111..173 /gene=\"EMP2\" /gene_synonym=\"XMP\" /note=\"propagated from UniProtKB/Swiss-Prot (P54851.1); transmembrane region\" misc_feature 240..242 /gene=\"EMP2\" /gene_synonym=\"XMP\" /note=\"N-linked (GlcNAc...) asparagine. /...","source":"Homo sapiens (human)","symbol":"EMP2","synonym":"XMP","version":"NM_001424.6"},{"aa_position":[],"accession":"NM_001109763","definition":"Homo sapiens GSG1 like (GSG1L), transcript variant 1, mRNA.","division":"RefSeq","geneid":"146395","gi":"","length":"5128","nt_position":[],"snippet":"propagated from UniProtKB/Swiss-Prot (Q6UXU4.2); transmembrane region\" misc_feature 360..686 /gene=\"GSG1L\" /gene_synonym=\"PRO19651\" /note=\"GSG1-like protein; Region: GSG-1; pfam07803\" /db_xref=\"CDD:462270\" misc_feature <594..995 /gene=\"GSG1L\" /gene_synonym=\"PRO19651\" /note=\"PMP-22/EMP/MP20/Claudin family; Region: PMP22_Claudin; cl21598\" /db_xref=\"CDD:473919\" misc_feature 687..749 /gene=\"GSG1L\" /gene_synonym=\"PRO19651\" /note=\"propagated from UniProtKB/Swiss-Prot (Q6UXU4.2); transmembrane region\" misc_feature 810..872 /gene=\"GSG1L\" /gene_synonym=\"PRO19651\" /note=\"propagated from UniProtKB/Swiss-...","source":"Homo sapiens (human)","symbol":"GSG1L","synonym":"PRO19651","version":"NM_001109763.2"},{"aa_position":[],"accession":"NM_001379051","definition":"Homo sapiens calcium voltage-gated channel auxiliary subunit gamma 2 (CACNG2), transcript variant 2, mRNA.","division":"RefSeq","geneid":"10369","gi":"","length":"5351","nt_position":[],"snippet":"misc_feature 955..1476 /gene=\"CACNG2\" /gene_synonym=\"MRD10\" /note=\"PMP-22/EMP/MP20/Claudin family; Region: PMP22_Claudin; cl21598\" /db_xref=\"CDD:473919\" variation 957 /gene=\"CACNG2\" /gene_synonym=\"MRD10\" /replace=\"a\" /replace=\"g\" /db_xref=\"dbSNP:2517782430\" variation 959 /gene=\"CACNG2\" /gene_synonym=\"MRD10\" /replace=\"c\" /replace=\"t\" /db_xref=\"dbSNP:753360030\" variation 960 /gene=\"CACNG2\" /gene_synonym=\"MRD10\" /replace=\"c\" /replace=\"t\" /db_xref=\"dbSNP:765903646\" variation 967 /gene=\"CACNG2\" /gene_synonym=\"MRD10\" /replace=\"c\" /replace=\"g\" /db_xref=\"dbSNP:2517782418\" variation 969 /gene=\"...","source":"Homo sapiens (human)","symbol":"CACNG2","synonym":"MRD10","version":"NM_001379051.1"},{"aa_position":[],"accession":"NM_001323900","definition":"Homo sapiens GSG1 like (GSG1L), transcript variant 3, mRNA.","division":"RefSeq","geneid":"146395","gi":"","length":"5182","nt_position":[],"snippet":"misc_feature 360..686 /gene=\"GSG1L\" /gene_synonym=\"PRO19651\" /note=\"GSG1-like protein; Region: GSG-1; pfam07803\" /db_xref=\"CDD:462270\" misc_feature <594..995 /gene=\"GSG1L\" /gene_synonym=\"PRO19651\" /note=\"PMP-22/EMP/MP20/Claudin family; Region: PMP22_Claudin; cl21598\" /db_xref=\"CDD:473919\" variation 293..294 /gene=\"GSG1L\" /gene_synonym=\"PRO19651\" /replace=\"\" /replace=\"ga\" /db_xref=\"dbSNP:2506724862\" variation 294 /gene=\"GSG1L\" /gene_synonym=\"PRO19651\" /replace=\"a\" /replace=\"g\" /db_xref=\"dbSNP:2506724854\" variation 295 /gene=\"GSG1L\" /gene_synonym=\"PRO19651\" /replace=\"a\" /replace=\"c\" /db_xref=\"...","source":"Homo sapiens (human)","symbol":"GSG1L","synonym":"PRO19651","version":"NM_001323900.2"},{"aa_position":[],"accession":"NM_006078","definition":"Homo sapiens calcium voltage-gated channel auxiliary subunit gamma 2 (CACNG2), transcript variant 1, mRNA.","division":"RefSeq","geneid":"10369","gi":"","length":"5642","nt_position":[],"snippet":"misc_feature 1192..1767 /gene=\"CACNG2\" /gene_synonym=\"MRD10\" /note=\"PMP-22/EMP/MP20/Claudin family; Region: PMP22_Claudin; pfam00822\" /db_xref=\"CDD:395662\" misc_feature 1204..1266 /gene=\"CACNG2\" /gene_synonym=\"MRD10\" /note=\"propagated from UniProtKB/Swiss-Prot (Q9Y698.1); transmembrane region\" misc_feature 1318..1320 /gene=\"CACNG2\" /gene_synonym=\"MRD10\" /note=\"N-linked (GlcNAc...) asparagine. /evidence=ECO:0000255; propagated from UniProtKB/Swiss-Prot (Q9Y698.1); glycosylation site\" misc_feature 1486..1548 /gene=\"CACNG2\" /gene_synonym=\"MRD10\" /note=\"propagated from UniProtKB/Swiss-Prot...","source":"Homo sapiens (human)","symbol":"CACNG2","synonym":"MRD10","version":"NM_006078.5"},{"aa_position":[],"accession":"NM_153685","definition":"Homo sapiens PILR alpha associated neural protein (PIANP), transcript variant 1, mRNA.","division":"RefSeq","geneid":"196500","gi":"","length":"2339","nt_position":[],"snippet":"juxtamembrane region and modulates barrier properties and E-Cadherin processing JOURNAL Biochem Biophys Res Commun 475 (4), 342-349 (2016) PUBMED 27216462 REMARK GeneRIF: Functionally, Leda-1/Pianp increased the transepithelial electrical resistance generated by a polarized cell sheet. While Claudin 1 and 4 expression and activities of small GTPases were not affected, gamma-Secretase-mediated cleavage of E-Cadherin was attenuated by Leda-1/Pianp. REFERENCE 3 (bases 1 to 2339) AUTHORS Evdokimov,K., Biswas,S., Adrian,M., Weber,J., Schledzewski,K., Winkler,M., Goerdt,S. and Geraud,C. TITLE...","source":"Homo sapiens (human)","symbol":"PIANP","synonym":"C12orf53; leda-1; LEDA1; PANP","version":"NM_153685.4"},{"aa_position":[],"accession":"NM_001244015","definition":"Homo sapiens PILR alpha associated neural protein (PIANP), transcript variant 3, mRNA.","division":"RefSeq","geneid":"196500","gi":"","length":"2418","nt_position":[],"snippet":"juxtamembrane region and modulates barrier properties and E-Cadherin processing JOURNAL Biochem Biophys Res Commun 475 (4), 342-349 (2016) PUBMED 27216462 REMARK GeneRIF: Functionally, Leda-1/Pianp increased the transepithelial electrical resistance generated by a polarized cell sheet. While Claudin 1 and 4 expression and activities of small GTPases were not affected, gamma-Secretase-mediated cleavage of E-Cadherin was attenuated by Leda-1/Pianp. REFERENCE 3 (bases 1 to 2418) AUTHORS Evdokimov,K., Biswas,S., Adrian,M., Weber,J., Schledzewski,K., Winkler,M., Goerdt,S. and Geraud,C. TITLE...","source":"Homo sapiens (human)","symbol":"PIANP","synonym":"C12orf53; leda-1; LEDA1; PANP","version":"NM_001244015.2"},{"aa_position":[],"accession":"NM_145811","definition":"Homo sapiens calcium voltage-gated channel auxiliary subunit gamma 5 (CACNG5), transcript variant 1, mRNA.","division":"RefSeq","geneid":"27091","gi":"","length":"10576","nt_position":[],"snippet":"misc_feature 259..321 /gene=\"CACNG5\" /note=\"propagated from UniProtKB/Swiss-Prot (Q9UF02.2); transmembrane region\" misc_feature 289..822 /gene=\"CACNG5\" /note=\"PMP-22/EMP/MP20/Claudin family; Region: PMP22_Claudin; cl21598\" /db_xref=\"CDD:473919\" misc_feature 544..606 /gene=\"CACNG5\" /note=\"propagated from UniProtKB/Swiss-Prot (Q9UF02.2); transmembrane region\" misc_feature 622..684 /gene=\"CACNG5\" /note=\"propagated from UniProtKB/Swiss-Prot (Q9UF02.2); transmembrane region\" misc_feature 763..825 /gene=\"CACNG5\" /note=\"propagated from UniProtKB/Swiss-Prot (Q9UF02.2); transmembrane region\" variation...","source":"Homo sapiens (human)","symbol":"CACNG5","synonym":"","version":"NM_145811.3"},{"aa_position":[],"accession":"NM_001195278","definition":"Homo sapiens transmembrane protein 178B (TMEM178B), mRNA.","division":"RefSeq","geneid":"100507421","gi":"","length":"10726","nt_position":[],"snippet":"note=\"/evidence=ECO:0000255; propagated from UniProtKB/Swiss-Prot (H3BS89.1)\" mat_peptide 317..1129 /gene=\"TMEM178B\" /product=\"Transmembrane protein 178B. /id=PRO_0000419261\" /note=\"propagated from UniProtKB/Swiss-Prot (H3BS89.1)\" misc_feature 545..1045 /gene=\"TMEM178B\" /note=\"PMP-22/EMP/MP20/Claudin family; Region: PMP22_Claudin; cl21598\" /db_xref=\"CDD:473919\" misc_feature 689..691 /gene=\"TMEM178B\" /note=\"N-linked (GlcNAc...) asparagine. /evidence=ECO:0000255; propagated from UniProtKB/Swiss-Prot (H3BS89.1); glycosylation site\" misc_feature 701..703 /gene=\"TMEM178B\" /note=\"N-linked...","source":"Homo sapiens (human)","symbol":"TMEM178B","synonym":"","version":"NM_001195278.2"},{"aa_position":[],"accession":"NM_001244014","definition":"Homo sapiens PILR alpha associated neural protein (PIANP), transcript variant 2, mRNA.","division":"RefSeq","geneid":"196500","gi":"","length":"2711","nt_position":[],"snippet":"juxtamembrane region and modulates barrier properties and E-Cadherin processing JOURNAL Biochem Biophys Res Commun 475 (4), 342-349 (2016) PUBMED 27216462 REMARK GeneRIF: Functionally, Leda-1/Pianp increased the transepithelial electrical resistance generated by a polarized cell sheet. While Claudin 1 and 4 expression and activities of small GTPases were not affected, gamma-Secretase-mediated cleavage of E-Cadherin was attenuated by Leda-1/Pianp. REFERENCE 3 (bases 1 to 2711) AUTHORS Evdokimov,K., Biswas,S., Adrian,M., Weber,J., Schledzewski,K., Winkler,M., Goerdt,S. and Geraud,C. TITLE...","source":"Homo sapiens (human)","symbol":"PIANP","synonym":"C12orf53; leda-1; LEDA1; PANP","version":"NM_001244014.2"},{"aa_position":[],"accession":"NM_001393385","definition":"Homo sapiens capping protein inhibiting regulator of actin dynamics (CRACD), transcript variant 6, mRNA.","division":"RefSeq","geneid":"57482","gi":"","length":"6691","nt_position":[],"snippet":"and metastasis via CRAD-dependent mechanotransduction. REFERENCE 2 (bases 1 to 6691) AUTHORS Cui,A., Xue,Y., Wang,X., Huang,Y., Han,X., Li,X., Niu,D., Niu,S., Zhao,Y., Yang,X. and Yu,W. TITLE Knockdown of CRAD suppresses the growth and promotes the apoptosis of human lung cancer cells via Claudin 4 JOURNAL Biosci Rep 40 (10) (2020) PUBMED 33006362 REMARK GeneRIF: Knockdown of CRAD suppresses the growth and promotes the apoptosis of human lung cancer cells via Claudin 4. REFERENCE 3 (bases 1 to 6691) AUTHORS Zhou,M., Fan,J., Li,Z., Li,P., Sun,Y., Yang,Y., Zhou,X., Wang,J., Wang,Y., Qi,H., Cai,W...","source":"Homo sapiens (human)","symbol":"CRACD","synonym":"CRAD; KIAA1211","version":"NM_001393385.1"},{"aa_position":[],"accession":"NM_001393383","definition":"Homo sapiens capping protein inhibiting regulator of actin dynamics (CRACD), transcript variant 4, mRNA.","division":"RefSeq","geneid":"57482","gi":"","length":"6761","nt_position":[],"snippet":"and metastasis via CRAD-dependent mechanotransduction. REFERENCE 2 (bases 1 to 6761) AUTHORS Cui,A., Xue,Y., Wang,X., Huang,Y., Han,X., Li,X., Niu,D., Niu,S., Zhao,Y., Yang,X. and Yu,W. TITLE Knockdown of CRAD suppresses the growth and promotes the apoptosis of human lung cancer cells via Claudin 4 JOURNAL Biosci Rep 40 (10) (2020) PUBMED 33006362 REMARK GeneRIF: Knockdown of CRAD suppresses the growth and promotes the apoptosis of human lung cancer cells via Claudin 4. REFERENCE 3 (bases 1 to 6761) AUTHORS Zhou,M., Fan,J., Li,Z., Li,P., Sun,Y., Yang,Y., Zhou,X., Wang,J., Wang,Y., Qi,H., Cai,W...","source":"Homo sapiens (human)","symbol":"CRACD","synonym":"CRAD; KIAA1211","version":"NM_001393383.1"},{"aa_position":[],"accession":"NM_001393382","definition":"Homo sapiens capping protein inhibiting regulator of actin dynamics (CRACD), transcript variant 3, mRNA.","division":"RefSeq","geneid":"57482","gi":"","length":"6827","nt_position":[],"snippet":"and metastasis via CRAD-dependent mechanotransduction. REFERENCE 2 (bases 1 to 6827) AUTHORS Cui,A., Xue,Y., Wang,X., Huang,Y., Han,X., Li,X., Niu,D., Niu,S., Zhao,Y., Yang,X. and Yu,W. TITLE Knockdown of CRAD suppresses the growth and promotes the apoptosis of human lung cancer cells via Claudin 4 JOURNAL Biosci Rep 40 (10) (2020) PUBMED 33006362 REMARK GeneRIF: Knockdown of CRAD suppresses the growth and promotes the apoptosis of human lung cancer cells via Claudin 4. REFERENCE 3 (bases 1 to 6827) AUTHORS Zhou,M., Fan,J., Li,Z., Li,P., Sun,Y., Yang,Y., Zhou,X., Wang,J., Wang,Y., Qi,H., Cai,W...","source":"Homo sapiens (human)","symbol":"CRACD","synonym":"CRAD; KIAA1211","version":"NM_001393382.1"},{"aa_position":[],"accession":"NM_001393384","definition":"Homo sapiens capping protein inhibiting regulator of actin dynamics (CRACD), transcript variant 5, mRNA.","division":"RefSeq","geneid":"57482","gi":"","length":"6908","nt_position":[],"snippet":"and metastasis via CRAD-dependent mechanotransduction. REFERENCE 2 (bases 1 to 6908) AUTHORS Cui,A., Xue,Y., Wang,X., Huang,Y., Han,X., Li,X., Niu,D., Niu,S., Zhao,Y., Yang,X. and Yu,W. TITLE Knockdown of CRAD suppresses the growth and promotes the apoptosis of human lung cancer cells via Claudin 4 JOURNAL Biosci Rep 40 (10) (2020) PUBMED 33006362 REMARK GeneRIF: Knockdown of CRAD suppresses the growth and promotes the apoptosis of human lung cancer cells via Claudin 4. REFERENCE 3 (bases 1 to 6908) AUTHORS Zhou,M., Fan,J., Li,Z., Li,P., Sun,Y., Yang,Y., Zhou,X., Wang,J., Wang,Y., Qi,H., Cai,W...","source":"Homo sapiens (human)","symbol":"CRACD","synonym":"CRAD; KIAA1211","version":"NM_001393384.1"},{"aa_position":[],"accession":"NM_020722","definition":"Homo sapiens capping protein inhibiting regulator of actin dynamics (CRACD), transcript variant 2, mRNA.","division":"RefSeq","geneid":"57482","gi":"","length":"6898","nt_position":[],"snippet":"and metastasis via CRAD-dependent mechanotransduction. REFERENCE 2 (bases 1 to 6898) AUTHORS Cui,A., Xue,Y., Wang,X., Huang,Y., Han,X., Li,X., Niu,D., Niu,S., Zhao,Y., Yang,X. and Yu,W. TITLE Knockdown of CRAD suppresses the growth and promotes the apoptosis of human lung cancer cells via Claudin 4 JOURNAL Biosci Rep 40 (10) (2020) PUBMED 33006362 REMARK GeneRIF: Knockdown of CRAD suppresses the growth and promotes the apoptosis of human lung cancer cells via Claudin 4. REFERENCE 3 (bases 1 to 6898) AUTHORS Zhou,M., Fan,J., Li,Z., Li,P., Sun,Y., Yang,Y., Zhou,X., Wang,J., Wang,Y., Qi,H., Cai,W...","source":"Homo sapiens (human)","symbol":"CRACD","synonym":"CRAD; KIAA1211","version":"NM_020722.2"},{"aa_position":[],"accession":"NM_001393381","definition":"Homo sapiens capping protein inhibiting regulator of actin dynamics (CRACD), transcript variant 1, mRNA.","division":"RefSeq","geneid":"57482","gi":"","length":"7044","nt_position":[],"snippet":"and metastasis via CRAD-dependent mechanotransduction. REFERENCE 2 (bases 1 to 7044) AUTHORS Cui,A., Xue,Y., Wang,X., Huang,Y., Han,X., Li,X., Niu,D., Niu,S., Zhao,Y., Yang,X. and Yu,W. TITLE Knockdown of CRAD suppresses the growth and promotes the apoptosis of human lung cancer cells via Claudin 4 JOURNAL Biosci Rep 40 (10) (2020) PUBMED 33006362 REMARK GeneRIF: Knockdown of CRAD suppresses the growth and promotes the apoptosis of human lung cancer cells via Claudin 4. REFERENCE 3 (bases 1 to 7044) AUTHORS Zhou,M., Fan,J., Li,Z., Li,P., Sun,Y., Yang,Y., Zhou,X., Wang,J., Wang,Y., Qi,H., Cai,W...","source":"Homo sapiens (human)","symbol":"CRACD","synonym":"CRAD; KIAA1211","version":"NM_001393381.1"},{"aa_position":[],"accession":"XM_047443422","definition":"PREDICTED: Homo sapiens transmembrane protein 178A (TMEM178A), transcript variant X6, mRNA.","division":"RefSeq","geneid":"130733","gi":"","length":"14976","nt_position":[],"snippet":"id=\"XP_047299378.1\" /db_xref=\"GeneID:130733\" /db_xref=\"HGNC:HGNC:28517\" /translation=\"MAVAVLLCGCIVATVSFFWEESLTQHVAGLLFLMTGIFCTISLCTYAASISYDLNRLPKLIYSLPADVEHGYSWSIFCAWCSLGFIVAAGGLCIAYPFISRTKIAQLKSGRDSTV\" misc_feature <13920..14192 /gene=\"TMEM178A\" /gene_synonym=\"TMEM178\" /note=\"PMP-22/EMP/MP20/Claudin family; Region: PMP22_Claudin; cl21598\" /db_xref=\"CDD:473919\" variation 13917 /gene=\"TMEM178A\" /gene_synonym=\"TMEM178\" /replace=\"a\" /replace=\"g\" /db_xref=\"dbSNP:2465487445\" variation 13922 /gene=\"TMEM178A\" /gene_synonym=\"TMEM178\" /replace=\"c\" /replace=\"g\" /replace=\"t\" /db_xref=\"dbSNP:141844962\"...","source":"Homo sapiens (human)","symbol":"TMEM178A","synonym":"TMEM178","version":"XM_047443422.1"},{"aa_position":[],"accession":"NR_046207","definition":"Homo sapiens solute carrier family 12 member 2 (SLC12A2), transcript variant 3, non-coding RNA.","division":"RefSeq","geneid":"6558","gi":"","length":"6940","nt_position":[],"snippet":". REFERENCE 4 (bases 1 to 6940) AUTHORS Koumangoye,R., Penny,P. and Delpire,E. TITLE Loss of NKCC1 function increases epithelial tight junction permeability by upregulating claudin-2 expression JOURNAL Am J Physiol Cell Physiol 323 (4), C1251-C1263 (2022) PUBMED 35968893 REMARK GeneRIF: Loss of NKCC1 function increases epithelial tight junction permeability by upregulating claudin-2 expression. REFERENCE 5 (bases 1 to 6940) AUTHORS Mohaghghegh,H., Ananloo,E.S., Hadjighasem,M...","source":"Homo sapiens (human)","symbol":"SLC12A2","synonym":"BSC; BSC-2; BSC2; CCC1; hNKCC1; KILQS; NKCC1; PPP1R141","version":"NR_046207.2"},{"aa_position":[],"accession":"NM_001256461","definition":"Homo sapiens solute carrier family 12 member 2 (SLC12A2), transcript variant 2, mRNA.","division":"RefSeq","geneid":"6558","gi":"","length":"6826","nt_position":[],"snippet":". REFERENCE 4 (bases 1 to 6826) AUTHORS Koumangoye,R., Penny,P. and Delpire,E. TITLE Loss of NKCC1 function increases epithelial tight junction permeability by upregulating claudin-2 expression JOURNAL Am J Physiol Cell Physiol 323 (4), C1251-C1263 (2022) PUBMED 35968893 REMARK GeneRIF: Loss of NKCC1 function increases epithelial tight junction permeability by upregulating claudin-2 expression. REFERENCE 5 (bases 1 to 6826) AUTHORS Mohaghghegh,H., Ananloo,E.S., Hadjighasem,M...","source":"Homo sapiens (human)","symbol":"SLC12A2","synonym":"BSC; BSC-2; BSC2; CCC1; hNKCC1; KILQS; NKCC1; PPP1R141","version":"NM_001256461.2"},{"aa_position":[],"accession":"NM_001046","definition":"Homo sapiens solute carrier family 12 member 2 (SLC12A2), transcript variant 1, mRNA.","division":"RefSeq","geneid":"6558","gi":"","length":"6874","nt_position":[],"snippet":". REFERENCE 4 (bases 1 to 6874) AUTHORS Koumangoye,R., Penny,P. and Delpire,E. TITLE Loss of NKCC1 function increases epithelial tight junction permeability by upregulating claudin-2 expression JOURNAL Am J Physiol Cell Physiol 323 (4), C1251-C1263 (2022) PUBMED 35968893 REMARK GeneRIF: Loss of NKCC1 function increases epithelial tight junction permeability by upregulating claudin-2 expression. REFERENCE 5 (bases 1 to 6874) AUTHORS Mohaghghegh,H., Ananloo,E.S., Hadjighasem,M...","source":"Homo sapiens (human)","symbol":"SLC12A2","synonym":"BSC; BSC-2; BSC2; CCC1; hNKCC1; KILQS; NKCC1; PPP1R141","version":"NM_001046.3"},{"aa_position":[],"accession":"NM_016441","definition":"Homo sapiens cysteine rich transmembrane BMP regulator 1 (CRIM1), mRNA.","division":"RefSeq","geneid":"51232","gi":"","length":"6060","nt_position":[],"snippet":"and may play an important role in the in the pathogenesis of pterygium. REFERENCE 5 (bases 1 to 6060) AUTHORS Ogasawara,N., Kudo,T., Sato,M., Kawasaki,Y., Yonezawa,S., Takahashi,S., Miyagi,Y., Natori,Y. and Sugiyama,A. TITLE Reduction of Membrane Protein CRIM1 Decreases E-Cadherin and Increases Claudin-1 and MMPs, Enhancing the Migration and Invasion of Renal Carcinoma Cells JOURNAL Biol Pharm Bull 41 (4), 604-611 (2018) PUBMED 29607933 REMARK GeneRIF: CRIM1 regulates the expression of several epithelial-mesenchymal transition (EMT) related factors and appears to play a role in suppressing...","source":"Homo sapiens (human)","symbol":"CRIM1","synonym":"CRIM-1; S52","version":"NM_016441.3"}],"summary":[{"count":253,"keyword":"claudin"},{"count":253,"keyword":"[INTERSECTION]"}],"time":"2026-05-17 17:27:09","version":"GGRNA.v2 : RefSeq release 233 (Jan, 2026)"}