LOCUS       XM_054363527            1468 bp    mRNA    linear   PRI 05-OCT-2023
DEFINITION  PREDICTED: Homo sapiens Zn regulated GTPase metalloprotein
            activator 1F (ZNG1F), transcript variant X6, mRNA.
ACCESSION   XM_054363527
VERSION     XM_054363527.1
DBLINK      BioProject: PRJNA807723
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_060933) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_009914755.1-RS_2023_10
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.2
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 10/02/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1468
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /isolate="CHM13"
                     /db_xref="taxon:9606"
                     /chromosome="9"
                     /sex="female"
                     /cell_line="CHM13htert"
                     /tissue_type="hydatidiform mole"
                     /note="haploid cell line"
     gene            1..1468
                     /gene="ZNG1F"
                     /gene_synonym="CBWD6; CBWD7"
                     /note="Zn regulated GTPase metalloprotein activator 1F;
                     Derived by automated computational analysis using gene
                     prediction method: Gnomon. Supporting evidence includes
                     similarity to: 34 ESTs, 279 long SRA reads, 2 Proteins,
                     and 100% coverage of the annotated genomic feature by
                     RNAseq alignments, including 117 samples with support for
                     all annotated introns"
                     /db_xref="GeneID:644019"
                     /db_xref="HGNC:HGNC:31978"
     CDS             60..1043
                     /gene="ZNG1F"
                     /gene_synonym="CBWD6; CBWD7"
                     /codon_start=1
                     /product="zinc-regulated GTPase metalloprotein activator
                     1F isoform X6"
                     /protein_id="XP_054219502.1"
                     /db_xref="GeneID:644019"
                     /db_xref="HGNC:HGNC:31978"
                     /translation="

MLPAVGSVDEEEDPAEEDCPELVPIETTQSEEEEKSGLGAKIPVTIITGYLGAGKTTLLNYILTEQHSKRVAVILNESGEGSALEKSLAVSQGGELYEEWLELRNGCLCCSVKDNGLRAIENLMQKKGKFDDILLETTGLADPGIITIVDSKYGLKHLTEEKPDGLINEATRSINGLGQILETQRSSLQKKLQHVPGTQPHLDQSIVTITFDVPGNAKEEHLNMFIQNLLWEKNVRNKDNHCMEVIRLKGLVSIKDKSQQVIVQGVHELCDLEETPVSWKDDTERTNRLVLIGRNLDKDILKQLFIATVTETEKQWTTHFKEDQVCT"

     misc_feature    <114..>245
                     /gene="ZNG1F"
                     /gene_synonym="CBWD6; CBWD7"
                     /note="Predicted ATPase of the ABC class [General function
                     prediction only]; Region: COG3044"
                     /db_xref="CDD:225586"
     misc_feature    186..617
                     /gene="ZNG1F"
                     /gene_synonym="CBWD6; CBWD7"
                     /note="cobalamin synthesis protein CobW; Region:
                     CobW-like; cd03112"
                     /db_xref="CDD:349766"
     misc_feature    order(213..230,465..467,543..545)
                     /gene="ZNG1F"
                     /gene_synonym="CBWD6; CBWD7"
                     /note="putative active site [active]"
                     /db_xref="CDD:349766"
     misc_feature    order(282..284,297..299,384..386)
                     /gene="ZNG1F"
                     /gene_synonym="CBWD6; CBWD7"
                     /note="Zn binding site [ion binding]; other site"
                     /db_xref="CDD:349766"
     misc_feature    675..974
                     /gene="ZNG1F"
                     /gene_synonym="CBWD6; CBWD7"
                     /note="Cobalamin synthesis protein cobW C-terminal domain;
                     Region: CobW_C; pfam07683"
                     /db_xref="CDD:429593"
ORIGIN      

gcggtacggcgtgttggtcccagcggttcagctgaggtagggacgtgctgtaggccggaatgttaccggctgttggatctgtggatgaggaagaggatcctgcggaggaggattgtcctgaattggttcccattgagacgacgcaaagcgaggaggaggaaaagtctggcctcggcgccaagatcccagtcacaattatcaccgggtatttaggtgctgggaagacaacacttctgaactatattttgacagagcaacatagtaaaagagtagcggtcattttaaatgaatctggggaaggaagtgcgctggagaaatccttagctgtcagccaaggtggagagctctatgaagagtggctggaacttagaaacggttgcctctgctgttcagtgaaggacaatggccttagagctattgagaatttgatgcaaaagaaggggaaatttgatgacatactgttagagaccactggattagcagaccctggtatcataactattgtggattcaaaatatggattaaaacatttaacagaagagaaacctgatggccttatcaatgaagctactagatccataaatggactaggacaaatcttagaaacacaaagatcaagtttgcagaaaaaacttcagcatgtgccaggaacacaacctcaccttgatcagagtattgttacaatcacatttgacgtaccaggaaatgcaaaggaagaacatcttaatatgtttattcagaatcttctgtgggaaaagaatgtgagaaacaaggacaatcactgcatggaggtcataaggctgaagggattggtgtcaatcaaagacaaatcacaacaagtgattgtccagggtgtccatgagctctgtgatctggaggagactccagtgagctggaaggatgacactgagagaacaaatcgattggtcctcattggcagaaatttagataaggatatccttaaacagctgtttatagctactgtgacagaaacagaaaagcagtggacaacacatttcaaagaagatcaagtttgtacataacactagaggcatttcttatcaaaaggattggataataaaaataagtttctactgggtatatttcaagcatttatttattactttagttacgaattccaatatactttaaaatggtatttgttttacagcatacataaaatgtagcaaatcagtactgtaaaacatttaacattcatacaattatatataatatccttttttttaaagaatggtatttcacaaaaatatcttttgaaattggctttggagtttacatatactgaacatgaaagtttataataatgatgatacaactttcaacattgtcattttttcttagaacttcagctgattgcagagatataatgattacattgttattaaatttttttaacacaagtaagtgtcaccattttatgacatgaaataaaaggttatgactgtta

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