LOCUS       XM_054348270            2549 bp    mRNA    linear   PRI 05-OCT-2023
DEFINITION  PREDICTED: Homo sapiens HESX homeobox 1 (HESX1), transcript variant
            X2, mRNA.
ACCESSION   XM_054348270
VERSION     XM_054348270.1
DBLINK      BioProject: PRJNA807723
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_060927) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_009914755.1-RS_2023_10
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.2
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 10/02/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2549
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /isolate="CHM13"
                     /db_xref="taxon:9606"
                     /chromosome="3"
                     /sex="female"
                     /cell_line="CHM13htert"
                     /tissue_type="hydatidiform mole"
                     /note="haploid cell line"
     gene            1..2549
                     /gene="HESX1"
                     /gene_synonym="ANF; CPHD5; RPX"
                     /note="HESX homeobox 1; Derived by automated computational
                     analysis using gene prediction method: Gnomon. Supporting
                     evidence includes similarity to: 4 mRNAs, 1 EST, 52 long
                     SRA reads, 1 Protein, and 99% coverage of the annotated
                     genomic feature by RNAseq alignments, including 8 samples
                     with support for all annotated introns"
                     /db_xref="GeneID:8820"
                     /db_xref="HGNC:HGNC:4877"
                     /db_xref="MIM:601802"
     CDS             1633..2190
                     /gene="HESX1"
                     /gene_synonym="ANF; CPHD5; RPX"
                     /codon_start=1
                     /product="homeobox expressed in ES cells 1 isoform X1"
                     /protein_id="XP_054204245.1"
                     /db_xref="GeneID:8820"
                     /db_xref="HGNC:HGNC:4877"
                     /db_xref="MIM:601802"
                     /translation="

MSPSLQEGAQLGENKPSTCSFSIERILGLDQKKDCVPLMKPHRPWADTCSSSGKDGNLCLHVPNPPSGISFPSVVDHPMPEERASKYENYFSASERLSLKRELSWYRGRRPRTAFTQNQIEVLENVFRVNCYPGIDIREDLAQKLNLEEDRIQIWFQNRRAKLKRSHRESQFLMAKKNFNTNLLE"

     misc_feature    order(1957..1971,1975..1977,2026..2028,2044..2046,
                     2083..2085,2089..2094,2101..2106,2110..2118,2122..2127)
                     /gene="HESX1"
                     /gene_synonym="ANF; CPHD5; RPX"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:238039"
     misc_feature    1963..2124
                     /gene="HESX1"
                     /gene_synonym="ANF; CPHD5; RPX"
                     /note="Homeobox domain; Region: Homeobox; pfam00046"
                     /db_xref="CDD:425441"
     misc_feature    order(1963..1965,1972..1974,2092..2094,2101..2106,
                     2113..2115)
                     /gene="HESX1"
                     /gene_synonym="ANF; CPHD5; RPX"
                     /note="specific DNA base contacts [nucleotide binding];
                     other site"
                     /db_xref="CDD:238039"
ORIGIN      

ggcggtggtcgggaggttcccgtgcggcgctaggctctcccgcgagcgcgggcgtcggaagcggcggaggtggcagtgtctgccctgggatggccttccctgcacgcgcgcgtttgtatctaaatcgcaggggaccgtctcttcctcagcttgccggcgcgaggagccagagcctcgagttagggccacacgggggaatttggggcgggttgacttttcccgcaacatattttgtcagagaccttggagaaagtcctactgctggcgccttttagtttcctcagatgataacattcccaactccgctcgaagcgtccagtcttaatcccctccagcagaatggtgctgactaactcagatgtctgagatccgcagctgtgtcaataatagggctttctggcaaacttgtgaacgtaggctcgaaattgtttttctggacgcttgaatatcagtatattcagttgaaaacatgtgattttgttgccagtttatcagttcctacctggcctcccgaggtcagtccttcaggactgacgctgcaactccaactcccatgtttcttttaaatcacaaaggaaaatatcttttaaaaatcaggatacactgattaattatgttagtaactaattggcatttgttgaatcaaaaagttttggaagcgttaaatagttttagcctctaattttacaataaagtgaagctcaaagttgggaatttgaccggatgagggctacaagcctatcctttcctcctccctcttcatctttcccaacctgtcaccctggctcgtttatgtctctgtatagttgtaggctttcatcattatacagagaaaataacaaagtaagtagtgtcttctaaacatctagccattaattccaccaatccattccattttcattcaagaaataccagagatgctgagtaaagattaattagctgcctggttccacagatacatgggaacaaatccagaatagtagtagctcaaatccaaatatagtaacaaatagaagttatatattttaaacgaaaatagtagattttcccatgatctcttgaaagaaaaataaaattatatttttaaagttttgttgagtagacttgcattgtagttttacggaattatttttagtgttacaatctttaaaagttttccccttagattgtttatcagccagtctctctctcccgaagagttctttagtttttgaggaagttgatttggaggcagttcttacaatgagttaagggttcccagttgtgttacagtttctttttccttgatatctcatttctactctgccaacaagaacaccatgcaccccagctctaaagaaggaagactttcaagaatggagtgtagtggcatgatcacagttcattgcagcctcaacctcctacgctcaagtgatcctcccacctgagcctcctgagtagctgggatcacaggcgcatgctaccacgcccggctgaaggtttttcaatttttgaagagacgaggtcccactgtgttgcccagcccccttgtcagcggagctataaggtgaactgcaggaagatcccagccctatacacgtggggcagagccagcagaggccagagctgttgctctgtgcagaccacgagaggatgtctcccagccttcaggaaggcgctcagctcggggaaaacaaaccctcaacttgctccttttcaattgagagaatcttaggactggaccagaagaaagactgtgttccattaatgaaaccccacaggccctgggcagacacctgcagctcatcagggaaagatggtaacttatgtctacatgtcccaaatcctcccagtgggatttcattccctagcgtggtggatcacccaatgccagaagaaagagcttcgaaatatgaaaattacttttcagcctcagaaagactgtctttgaaaagagagttgagttggtatagaggccgaagaccaagaactgcttttactcaaaaccagattgaagtgttagaaaatgtctttagagtaaactgctatcctggtatcgatattagagaagacttagctcaaaaattgaatctagaggaagacagaatccagatttggtttcaaaatcggcgtgcaaaactgaaaaggtcccatagagaatcacagtttctaatggcgaaaaaaaatttcaacacaaatctgctggaatagatagaaaactaaacaagtgaaattatcttctaattgcagagcatgaagaatcagtggaaatattaagtgttaaaatgtgatgttttctttcctgcatttaatctgaatattgtcattttttctgaaaatatattgtaaatactattatagcatggtacatatttgggcacttttagttatagtaaagaccttttatatatattttaataaacattttcagaaaagattgctattttttaagtaagccaaattaatctaataaattagtttgttaaaatcaatagactcatgactaagtgattccacaagctggattctaattataaagtatttcaagtaaaataatctgaagaacaaaa

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