LOCUS       XM_054341014            7198 bp    mRNA    linear   PRI 05-OCT-2023
DEFINITION  PREDICTED: Homo sapiens empty spiracles homeobox 1 (EMX1),
            transcript variant X2, mRNA.
ACCESSION   XM_054341014
VERSION     XM_054341014.1
DBLINK      BioProject: PRJNA807723
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_060926) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_009914755.1-RS_2023_10
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.2
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 10/02/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7198
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /isolate="CHM13"
                     /db_xref="taxon:9606"
                     /chromosome="2"
                     /sex="female"
                     /cell_line="CHM13htert"
                     /tissue_type="hydatidiform mole"
                     /note="haploid cell line"
     gene            1..7198
                     /gene="EMX1"
                     /note="empty spiracles homeobox 1; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 1
                     mRNA, 6 ESTs, 20 long SRA reads, 2 Proteins, and 62%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 8 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:2016"
                     /db_xref="HGNC:HGNC:3340"
                     /db_xref="MIM:600034"
     CDS             5902..6261
                     /gene="EMX1"
                     /codon_start=1
                     /product="homeobox protein EMX1 isoform X1"
                     /protein_id="XP_054196989.1"
                     /db_xref="GeneID:2016"
                     /db_xref="HGNC:HGNC:3340"
                     /db_xref="MIM:600034"
                     /translation="

MVASDVPQDGLLLHGPFARKPKRIRTAFSPSQLLRLERAFEKNHYVVGAERKQLAGSLSLSETQVKVWFQNRRTKYKRQKLEEEGPESEQKKKGSHHINRWRIATKQANGEDIDVTSND"

     misc_feature    order(5965..5979,5983..5985,6034..6036,6052..6054,
                     6091..6093,6097..6102,6109..6114,6118..6126,6130..6135)
                     /gene="EMX1"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:238039"
     misc_feature    order(5971..5973,5980..5982,6100..6102,6109..6114,
                     6121..6123)
                     /gene="EMX1"
                     /note="specific DNA base contacts [nucleotide binding];
                     other site"
                     /db_xref="CDD:238039"
     misc_feature    5974..6132
                     /gene="EMX1"
                     /note="Homeobox domain; Region: Homeobox; pfam00046"
                     /db_xref="CDD:425441"
ORIGIN      

caagcagtctttctgccacagcctcccaaagtgctgagattataggtgtgagccattgtacctggcttggagtaatgtttttgagcaaagcaaatgtacaggacatgcacagagaggcacagggagcacagagtccctggatgaatgctctggctggtggcagtattgtcacagggcaggctacccaaaggtgagcagaacacatgaggctagacaggtacaacttgctcatgaagagcctcgaatgccaagcttaggagtttgaactttattggaacactgacactaatagttaatgtttactgagtgcttactatgtgctaagagctatgcatgaatcacctcattctaattctcttaactctccacagcaggtcttattatttccagattgctgatgaaaaactgagtcacagagaggtaaaaaaaaaaaacaaaaacaccctgggtccagagttgtgtgaaaaaattttaacaggttagagttgtgttgtagaaatctggtagccagccacgtgtaagacgaattgtagaaaggagagatcacaaatggctatcataagagaatcactgggaaaaggtaataagaacccaaattagaggcaaggagaacagaaagaaatgaaagaatgcaaagactgactggatgtgcacagcagtgaccgagagaaaggaggtatcacaggtgcctcttagctgctaagcctgggtgtcctgcagaaaggggcagctattatcagaagagagaagccagagagaggcacagatttggtggggatgatgttgagctccgtttgggggtatggtgagtgtctagggggcctgtaggaacccctccagaaaaattctcacaagcatttgaaaatcagtgacttgatctggagaaaaatatagggctggcattacaaacctgccggggtctgcattacagtattggttgaaagtgtggaaattgataatgatagatggttggtagatacatagatagatagatagatagatagatagatagatagatagatagaataaatagcatgatacatggaatgagggaagggctaaggataaagatgccttcatggatgcccacagttaggagaagaaagtagagcccatgaaggaacaactcccagagtttgcagatccaggcaagtatcttgttcagaaaataaagggaagggagtttccaaaagaaaagggggttgaaggtactcagatgctgaggagcctataaacaattgtgactaaaaaagactcaaatttggaaataaggtgtcctaatgaacatttcagaggatggagagagattcttaaagtcagcctttggaagaataactatatagaacacttccagaggccaaactagtgacaatggatcaaaagaattaaaatattgcatatctggaaattacacagctagaaatatgtagaaaagaaacacaaacatgcggtaagatacagctatggagctgtttgtcgaaattttgttaaaacagtgaaaatctgtaaactgtattaatgtccaacaataaaaaatatttaatgagaggcaaagatgctttgattggttataaagataaagaagttacaatactatgtacagtatgatcctttttttaaagggaggcacatatagaaagaactggaaggatatactgtaagaatttcacgatgtttgtttctgggtagtaggatttgacaattataagatctctgttttcccttcactccccccttttggattatctgtattttttataactctgtccaatagacatataatgtgagacacataattttaaatgttctagtggccacatttaaaaagtagaaagaaacagataaaataatcttcttaagatatttcattttactcaatatatccattactatgtgtaatcgatataaaaatattaatattttaaatgttttagcactaagcctgtttaacactaaatgcagtggatattcacatttacagaacatctctgtttgggccatccacttctcaagcaccacattaccgcatttggcttctagcacggctctatgaaataatagcagttaatatttatcaaaagcctactatgttccaggcactgctccaagttcatcaggtggagattataactcattaggtctcaataactccatgaggttgaacttattgtgctctccacaagcacgtgttgcttgcccttgtcctcataccataatgaaatgtttggagcttttgcaaaagccattttcctaatatgatgggcatccaagtctggttgcaaaggcttggatagagggcaagtgagagaattggagagagactaaaaatcattcaagaaattttgtggtgaaaaagacaagtcaaaagactgagagaaacatgaggacagaaaactctttgtaaggcaaggagacataaagatgaagtcaggctgaataggaaagaaggaggtgaaaggtgaaagagagatggctgggggtgtggctggtccaaattctcacaagatctctgttggagaaacattgcctggcttgtgctggtggcgagatgtacatagcagcttctcagctagagggagcagggagtcatggccttgtgagggagacagatggagacacacacaacccccatcgcaggtgaatgctatgaaagaatggggtggagggcttcccagggagatgaactgagttttaagaacgaagttagccagcaaagaagcaaaaggaagaggatatagacttgaggattacatcactggatgactgagccactgattggatgtggaggatgagagagtgatgctttgaggtgattcccaagttctccgcatggacaaaggcagagacaataacttgtactgagtgctctttggagtctgacattgatccagtgcaccacatatgttatctcatttactcctcacagaggtcccgtataacgcttgcaatttcacagatacgcaagctgaggcaaaataattggcccagggctcaccactaataaataggagagtctggatttggggccaggttattccagaaatagagagagggagggaaaacgttaatgtggggccagagccagaacaggtaggctaggctgtatcagcctgggaggcatcgggctattctccaaaaagtgaggctccgggttgcaggagatgggacctccaggaaactggtgggaggctggacaggggcaaagtgaaaggtaagcagcctgaagatgggtgggatgtagtggactccagcgtgaagagcctccagtctctggcagagctcagcagcttgggtgggaggaaacgaagggcagggagcagaaggtggtggggggaacgggttttggttaagatgggcagctgtccagtggtgaagaggggaagtatttgtgtatacgatcagttgtgggggacggtggtagagggagcagtatgagagtctgggaggaacagggcaggggagatggcacaggagaagattggggtgggggtgggggcactgatactgaatccagtacacagaggcaggcttagagaccccctgagggtgacaaattcttctcttaacttgctgcagaggaaacgacaagagaataggtcctaagaggagtgaaaatagaggaaactggccaagggataaagataagcagagctatggaagaaaaggaagaaaattagggaattactggagaggaagctgacagaaaggggcgctgggagaggaaaaggtgagggaggacgaaaacggaactcctatcacccagcgcattccagcaccccctccccctcccccgggaagtctgcgactgcatcctcacagggatggaatgggagtggaagctaggccaggctgggaccccggggctgtcccagcccaaccaagacggtgaccagactcaagttactgatcctccgctgtttcttcatctgtaaagtggagttaatgacagacagctggatgtcaacgttttttgttgtttgttttagagatgggatctccctgtatcgcccaggctggagtgcagcggtatgatcacggctcactgcagcctcgacctcctgggctcgagagatcttcctgtctcagcctcccgagtagaaatgtcagcatttgaatgcctcacaagggaaggtggtgtaataaaaggtctattgatttagatatgaacaagtatacccagagccacacgaatgaaaggaggtggccagtgtagatgcaagtctaggacggtcggtagattccaagcttctctacctgcccagttaaacaagttcgtggcccctggccagcctctcggtgggggtctgcgacagaacgggtgggattcattaccaggctaggagcgcaaggccctcgggccgggttcagcttgctgggctcctgtcttgtctcagcccccagcacttgctctgtcaccgcagagcacaggcccaggcaacgtttacccaactgaacccgcatccctgtgggaaccttgttccaacaaaatcccgtcgttgtctccttccatatggaacgaaaatctccttctgtacctctgcccagctccgcacccccgcccccttagagatacggcctggtcgggtcctggtccccccctcggcggcgcttccacttttcccagactgagggtggggaaaaggaggagggggaagaaatcagaggaggaaaagtcgggaggtaggggagccgggagacaggagagggggaaaataaagagcctgagacacaaacgagaggaaaagaccatcacagaaagctggaaatctccggagaggccagcgagaacccgcgctccccacggattccatcattccttccgaaggcgcctctgcggtgtctcagccgtgccaggccccggggttcccaggacgcggaggagtgctgggtgcggccgcctcgcctccccacccctggccgcccctccccacctcgcccaagggggccggaacggcgtcggcgcgcgggggcttttcggagcagtcgagtggaaaatagactttaacccgctttgtggcggccggggcgccctgagcgctctccaaaccacggctcccggcgctcaggcgggccgctgccaagacccggcctggagtccccgcagagttgcgcggcgcacggaccccgtggccttggggcgtcaggaggcccaacccagatctgcgcgcccaggcagcgctcaggccgctagaatggaccccggcagcggcgaggaagcggaactctctgcggctccctctccgcagtgcgccggcaaggtccaggtcccagcctccccaccgccgcccgcgccctcctaggcctcggagcggcgcctttctgcggcctcgaaggtggggtgggaaagtttggggagtcccggctctcacagcctgtcgtgagaactgcccccggggaattcgtccgccgtacggaaaaactggccggagcagagtcgtccgcggttccgcggtcgcgggtggaaggtgaaggtcgagggaggtcaggctgcttctgcgtgtcctgacggctggcgtgttctcttgagatgggctcgggctacttggccagcttcaatttaagccacagtgtctccgaggccctgacctggtccggcccgccgacacttgagcccccagagcctcagagaaggcgagggggtggatctcccagtgccgaggcccgccgtcctggtccaagccggtcgcggcaccgtgtctgggcactggagctgcttccagccccgcgaacagctggagggtggcagtgggaccgctccggcggcttctcccgcgcagtgccccgcctggccccttgtgaagggagtgagcgtcccctttccagagctgtcccccgtgacatccagaaaacgcgaaacctcaggaacaaggtcgcagcttcagaccgcggcccaggaggccgatggtggccagcgacgtgccccaggacgggctgcttctgcacggccccttcgcacgcaagcccaagcggatccgcacggccttctcgccctcgcagctgctgcggctggagcgcgccttcgagaagaaccactacgtggtgggcgccgagcggaagcagctggccggcagtctcagcctctccgagacgcaggtgaaggtgtggttccagaaccggaggacaaagtacaaacggcagaagctggaggaggaagggcctgagtccgagcagaagaagaagggctcccatcacatcaaccggtggcgcattgccacgaagcaggccaatggggaggacatcgatgtcacctccaatgactagggtgggcaaccacaaacccacgagggcagagtgctgcttgctgctggccaggcccctgcgtgggcccaagctggactctggccactccctggccaggctttggggaggcctggagtcatggccccacagggcttgaagcccggggccgccattgacagagggacaagcaatgggctggctgaggcctgggaccacttggccttctcctcggagagcctgcctgcctgggcgggcccgcccgccaccgcagcctcccagctgctctccgtgtctccaatctcccttttgttttgatgcatttctgttttaatttattttccaggcaccactgtagtttagtgatccccagtgtcccccttccctatgggaataataaaagtctctctcttaatgacacgggcatccagctccagccccagagcctggggtggtagattccggctctgagggccagtgggggctggtagagcaaacgcgttcagggcctgggagcctggggtggggtactggtggagggggtcaagggtaattcattaactcctctcttttgttgggggaccctggtctctacctccagctccacagcaggagaaacaggctagacatagggaagggccatcctgtatcttgagggaggacaggcccaggtctttcttaacgtattgagaggtgggaatcaggcccaggtagttcaatgggagagggagagtgcttccctctgcctagagactctggtggcttctccagttgaggagaaaccagaggaaaggggaggattggggtctgggggagggaacaccattcacaaaggctgacggttccagtccgaagtcgtgggcccaccaggatgctcacctgtccttggagaaccgctgggcaggttgagactgcagagacagggcttaaggctgagcctgcaaccagtccccagtgactc

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