LOCUS       XM_054326698            2441 bp    mRNA    linear   PRI 05-OCT-2023
DEFINITION  PREDICTED: Homo sapiens four and a half LIM domains 1 (FHL1),
            transcript variant X2, mRNA.
ACCESSION   XM_054326698
VERSION     XM_054326698.1
DBLINK      BioProject: PRJNA807723
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_060947) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_009914755.1-RS_2023_10
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.2
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 10/02/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2441
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /isolate="CHM13"
                     /db_xref="taxon:9606"
                     /chromosome="X"
                     /sex="female"
                     /cell_line="CHM13htert"
                     /tissue_type="hydatidiform mole"
                     /note="haploid cell line"
     gene            1..2441
                     /gene="FHL1"
                     /gene_synonym="FCMSU; FHL-1; FHL1A; FHL1B; FLH1A; KYOT;
                     RBMX1A; RBMX1B; SLIM; SLIM-1; SLIM1; SLIMMER; XMPMA"
                     /note="four and a half LIM domains 1; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 58
                     ESTs, 1150 long SRA reads, 3 Proteins, and 100% coverage
                     of the annotated genomic feature by RNAseq alignments,
                     including 79 samples with support for all annotated
                     introns"
                     /db_xref="GeneID:2273"
                     /db_xref="HGNC:HGNC:3702"
                     /db_xref="MIM:300163"
     CDS             65..1036
                     /gene="FHL1"
                     /gene_synonym="FCMSU; FHL-1; FHL1A; FHL1B; FLH1A; KYOT;
                     RBMX1A; RBMX1B; SLIM; SLIM-1; SLIM1; SLIMMER; XMPMA"
                     /codon_start=1
                     /product="four and a half LIM domains protein 1 isoform
                     X2"
                     /protein_id="XP_054182673.1"
                     /db_xref="GeneID:2273"
                     /db_xref="HGNC:HGNC:3702"
                     /db_xref="MIM:300163"
                     /translation="

MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGKRTVSRVSHPVSKARKPPVCHGKRLPLTLFPSANLRGRHPGGERTCPSWVVVLYRKNRSLAAPRGPGLVKAPVWWPMKDNPGTTTASTAKNAP"

     misc_feature    <77..163
                     /gene="FHL1"
                     /gene_synonym="FCMSU; FHL-1; FHL1A; FHL1B; FLH1A; KYOT;
                     RBMX1A; RBMX1B; SLIM; SLIM-1; SLIM1; SLIMMER; XMPMA"
                     /note="LIM is a small protein-protein interaction domain,
                     containing two zinc fingers; Region: LIM; cl02475"
                     /db_xref="CDD:413332"
     misc_feature    182..343
                     /gene="FHL1"
                     /gene_synonym="FCMSU; FHL-1; FHL1A; FHL1B; FLH1A; KYOT;
                     RBMX1A; RBMX1B; SLIM; SLIM-1; SLIM1; SLIMMER; XMPMA"
                     /note="The first LIM domain of Four and a half LIM domains
                     protein 1; Region: LIM1_FHL1; cd09344"
                     /db_xref="CDD:188730"
     misc_feature    order(182..184,191..193,248..250,257..259,266..268,
                     275..277,329..331,338..340)
                     /gene="FHL1"
                     /gene_synonym="FCMSU; FHL-1; FHL1A; FHL1B; FLH1A; KYOT;
                     RBMX1A; RBMX1B; SLIM; SLIM-1; SLIM1; SLIMMER; XMPMA"
                     /note="Zn binding site [ion binding]; other site"
                     /db_xref="CDD:188730"
     misc_feature    365..538
                     /gene="FHL1"
                     /gene_synonym="FCMSU; FHL-1; FHL1A; FHL1B; FLH1A; KYOT;
                     RBMX1A; RBMX1B; SLIM; SLIM-1; SLIM1; SLIMMER; XMPMA"
                     /note="The second LIM domain of Four and a half LIM
                     domains protein 1 (FHL1); Region: LIM2_FHL1; cd09424"
                     /db_xref="CDD:188808"
     misc_feature    order(365..367,374..376,431..433,440..442,449..451,
                     458..460,512..514,521..523)
                     /gene="FHL1"
                     /gene_synonym="FCMSU; FHL-1; FHL1A; FHL1B; FLH1A; KYOT;
                     RBMX1A; RBMX1B; SLIM; SLIM-1; SLIM1; SLIMMER; XMPMA"
                     /note="Zn binding site [ion binding]; other site"
                     /db_xref="CDD:188808"
     misc_feature    548..706
                     /gene="FHL1"
                     /gene_synonym="FCMSU; FHL-1; FHL1A; FHL1B; FLH1A; KYOT;
                     RBMX1A; RBMX1B; SLIM; SLIM-1; SLIM1; SLIMMER; XMPMA"
                     /note="The third LIM domain of Four and a half LIM domains
                     protein 1 (FHL1); Region: LIM3_FHL1; cd09429"
                     /db_xref="CDD:188813"
     misc_feature    order(548..550,557..559,608..610,617..619,626..628,
                     635..637,689..691,698..700)
                     /gene="FHL1"
                     /gene_synonym="FCMSU; FHL-1; FHL1A; FHL1B; FLH1A; KYOT;
                     RBMX1A; RBMX1B; SLIM; SLIM-1; SLIM1; SLIMMER; XMPMA"
                     /note="Zn binding site [ion binding]; other site"
                     /db_xref="CDD:188813"
ORIGIN      

gtgagactttggggctttcagttagtggaagagctgcggtccctccagctacaaggtgggcaccatggcggagaagtttgactgccactactgcagggatcccttgcaggggaagaagtatgtgcaaaaggatggccaccactgctgcctgaaatgctttgacaagttctgtgccaacacctgtgtggaatgccgcaagcccatcggtgcggactccaaggaggtgcactataagaaccgcttctggcatgacacctgcttccgctgtgccaagtgccttcaccccttggccaatgagacctttgtggccaaggacaacaagatcctgtgcaacaagtgcaccactcgggaggactcccccaagtgcaaggggtgcttcaaggccattgtggcaggagatcaaaacgtggagtacaaggggaccgtctggcacaaagactgcttcacctgtagtaactgcaagcaagtcatcgggactggaagcttcttccctaaaggggaggacttctactgcgtgacttgccatgagaccaagtttgccaagcattgcgtgaagtgcaacaaggccatcacatctggaggaatcacttaccaggatcagccctggcatgccgattgctttgtgtgtgttacctgctctaagaagctggctgggcagcgtttcaccgctgtggaggaccagtattactgcgtggattgctacaagaactttgtggccaagaagtgtgctggatgcaagaaccccatcactgggaaaaggactgtgtcaagagtgagccacccagtctctaaagctaggaagcccccagtgtgccacgggaaacgcttgcctctcaccctgtttcccagcgccaacctccggggcaggcatccgggtggagagaggacttgtccctcgtgggtggtggttctttatagaaaaaatcgaagcttagcagctcctcgaggcccgggtttggtaaaggctccagtgtggtggcctatgaaggacaatcctggcacgactactgcttccactgcaaaaaatgctccgtgaatctggccaacaagcgctttgttttccaccaggagcaagtgtattgtcccgactgtgccaaaaagctgtaaactgacaggggctcctgtcctgtaaaatggcatttgaatctcgttctttgtgtccttactttctgccctataccatcaataggggaagagtggtccttcccttctttaaagttctccttccgtcttttctcccattttacagtattactcaaataagggcacacagtgatcatattagcatttagcaaaaagcaaccctgcagcaaagtgaatttctgtccggctgcaatttaaaaatgaaaacttaggtagattgactcttctgcatgtttctcatagagcagaaaagtgctaatcatttagccacttagtgatgtaagcaagaagcataggagataaaacccccactgagatgcctctcatgcctcagctgggacccaccgtgtagacacacgacatgcaagagttgcagcggctgctccaactcactgctcaccctcttctgtgagcaggaaaagaaccctactgacatgcatggtttaacttcctcatcagaactctgcccttccttctgttcttttgtgctttcaaataactaacacgaacttccagaaaattaacatttgaacttagctgtaattctaaactgacctttccccgtactaacgtttggtttccccgtgtggcatgttttctgagcgttcctactttaaagcatggaacatgcaggtgatttgggaagtgtagaaagacctgagaaaacgagcctgtttcagaggaacatcgtcacaacgaatacttctggaagcttaacaaaactaaccctgctgtcctttttattgtttttaattaatatttttgttttaattgatagcaaaatagtttatgggtttggaaacttgcatgaaaatattttagccccctcagatgttcctgcagtgctgaaattcatcctacagaagtaaccgcaaaactctagagggggagttgagcaggcgccagggctgtcatcaacatggatatgacatttcacaacagtgactagttgaatcccttgtaacgtagtagttgtctgctctttgtccatgtgttaatgaggactgcaaagtcccttctgttgtgattcctaggacttttcctcaagaggaaatctggatttccacctaccgcttacctgaaatgcaggatcacctacttactgtattctacattattatatgacatagtataatgagacaatatcaaaagtaaacatgtaatgacaatacatactaacattcttgtaggagtggttagagaagctgatgcctcatttctacattctgtcattagctattatcatctaacgtttcagtgtatccttacagaaataaagcagcatatgaataacctgc

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