LOCUS       XM_011546256            2705 bp    mRNA    linear   PRI 05-OCT-2023
DEFINITION  PREDICTED: Homo sapiens inactive glutathione hydrolase 2
            (LOC102724197), transcript variant X14, mRNA.
ACCESSION   XM_011546256
VERSION     XM_011546256.4
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NT_187386.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_011546256.3.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2023_10
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.2
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 10/02/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2705
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="22"
                     /map="unlocalized"
     gene            1..2705
                     /gene="LOC102724197"
                     /note="inactive glutathione hydrolase 2; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 13 Proteins, and 97% coverage of the annotated genomic
                     feature by RNAseq alignments"
                     /db_xref="GeneID:102724197"
     variation       1
                     /gene="LOC102724197"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2087108588"
     variation       167
                     /gene="LOC102724197"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2087108638"
     variation       189
                     /gene="LOC102724197"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2087108687"
     variation       683
                     /gene="LOC102724197"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2087108925"
     variation       708
                     /gene="LOC102724197"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:2087108962"
     variation       751
                     /gene="LOC102724197"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2087108997"
     variation       810
                     /gene="LOC102724197"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2087109027"
     CDS             833..2542
                     /gene="LOC102724197"
                     /codon_start=1
                     /product="inactive glutathione hydrolase 2 isoform X8"
                     /protein_id="XP_011544558.1"
                     /db_xref="GeneID:102724197"
                     /translation="

MKKKLVVLGLLAVVLVLVIVSLCLWLPSASKEPDNHVYTRAAVAADAKQCLEIGRDTLRDGGSAVDAAIAALLCVGLMNAHSMGIGVGLFLTIYNSTTHESEVINAREVAPRLAFASMFNSSEQSQKGGLSVAVPGEIRGYELAHQRHGRLPWARLFQPSIQLARQGFPVGKGLAAVLENKRTVIEQQPVLCEVFCRDRKVLWEGERLTLPRLADTYEMLAIEGAQAFYNGSLMAQIVKDIQAAGGIVTAEDLNNYCAELIEHPLNISLGDAVLYMPSARLSGPVLALILNILKGYNFSRESVETPEQKGLTYYRIVEAFRFAYAKRTLLGDPKFVDVTEVVRNMTSEFFTAQLRSQISDHTTHPISYYKPEFYTPDDGGTAHLSVVAEDGSAVSATSTINLYFGSKVCSPVSGILFNNEWTTSALPAFTNEFGAPPSPANFIQPGKQPLLSMCPTIMVGQDGQVRMVVGAAGGTQITTDTALAIIYNLWFGYDVKRAVEEPRLHNKLLPNVTTVERNIDQAVTAALETRHHHTQIASTFIAVVQAIVRTAGGWAAASDSRKGGEPAGY"

     misc_feature    995..2524
                     /gene="LOC102724197"
                     /note="Gamma-glutamyltranspeptidase; Region:
                     G_glu_transpept; pfam01019"
                     /db_xref="CDD:425991"
     variation       893
                     /gene="LOC102724197"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2087109772"
     variation       894
                     /gene="LOC102724197"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2087109826"
     variation       895
                     /gene="LOC102724197"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2087109887"
     variation       916
                     /gene="LOC102724197"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2087109948"
     variation       956
                     /gene="LOC102724197"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2087110002"
     variation       958
                     /gene="LOC102724197"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2087110068"
     variation       959
                     /gene="LOC102724197"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2087110123"
     variation       965
                     /gene="LOC102724197"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2087110190"
     variation       984
                     /gene="LOC102724197"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2087110268"
     variation       1017
                     /gene="LOC102724197"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:2087113219"
     variation       1114
                     /gene="LOC102724197"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2087113297"
     variation       1154
                     /gene="LOC102724197"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2087113433"
     variation       1178
                     /gene="LOC102724197"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2087113509"
     variation       1231
                     /gene="LOC102724197"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2087119285"
     variation       1250
                     /gene="LOC102724197"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:2087119369"
     variation       1288
                     /gene="LOC102724197"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2087119435"
     variation       1381
                     /gene="LOC102724197"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1556066253"
     variation       1382
                     /gene="LOC102724197"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2087119620"
     variation       1439
                     /gene="LOC102724197"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2087120283"
     variation       1464
                     /gene="LOC102724197"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:71226280"
     variation       1772
                     /gene="LOC102724197"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2087122402"
     variation       1805
                     /gene="LOC102724197"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2087122496"
     variation       1883
                     /gene="LOC102724197"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1556066369"
     polyA_site      2705
                     /gene="LOC102724197"
                     /experiment="COORDINATES: polyA evidence [ECO:0006239]"
ORIGIN      

actactgccaggtctctctgctcttggtgtctgcatccagggctgggagggggtcaaatgtatcacactatcggccccaggcccaccaagcctggggaggtggccacccttccatgatggcatttggatgttccctgtgtgtggggagggcacggggactccattcatagaccacctctgggacagtgtgtctgcctctgaggtcagacgctctgcactgggacagcgtggagtggagggaaaccaagcttggggctcattggaggggcttgctggcagacaccgccctttgtgggaaactgactgtgggagaggggaaccccaacctctgtcaccacatccctcttccctgttgtcacacctgtcacctgctgccgtagccatgagacttcccaagggtcactgctgccactcactgcacagcctggaagggagtccacaggggacatacagtgagcaagagacctgtgccactcaggcctcctgggggtgtccccagtgcagccatgatgataatcacagctaccattcaccaagccctgcccacagtctaacctactctattcacaacactcccagcagcaaggcaagtgaggtgctgccgtcatccaggctggacagttcagtgatttgcctgaggccccacagcaggagaacgagaaggctgcctgatcagagagtctctgaagaagattctgtggctacaggcttcagcagagtgtgagggagaccccggttatttcctcagctgtttccaccaaatcctcctgtctttcgtggccaacaccccaggcaaggcttggggcccccgtctgctgctggacgcagagccatgaagaagaagttagtggtgctgggcctgctggccgtggtcctggtgctggtcattgtcagcctctgtctctggctgccctcggcctccaaggaacctgacaaccatgtgtacaccagggctgccgtggccgcggatgccaagcagtgcttggagattgggagggacacactgcgggacggtggctctgcagtggatgcagccattgcagccctgttgtgtgtggggctcatgaatgcccacagcatgggcatcggggttggcctcttcctcaccatctacaacagcaccactcatgagtctgaggtcatcaatgcccgcgaggtggcccccaggctggcctttgccagcatgttcaacagctcggagcagtcccagaagggagggctgtcggtggcggtgcctggggagatccgaggctatgagctggcacaccagcggcatgggcggctgccctgggctcgcctcttccagcccagcatccagctggcccgccagggcttccccgtgggcaagggcttggcggcagtcctggaaaacaagcggaccgtcatcgagcagcagcctgtcttgtgtgaggtgttctgccgggatagaaaggtgctttgggagggggagagactgaccctgccgcggctggctgacacctacgagatgctggccatcgagggtgcccaggccttctacaacggcagcctcatggcccagattgtgaaggacatccaggcggctgggggcattgtgacagctgaggacctgaacaactactgtgctgagctgatcgagcacccgctgaacatcagcctgggagacgcggtgctgtacatgcccagtgcgcggctcagcgggcccgtgctggccctcatcctcaacatcctcaaagggtacaacttctcccgggagagcgtggagacccccgagcagaagggcctgacgtactaccgcatcgtagaggctttccggtttgcctacgccaagaggaccctgcttggggaccccaagtttgtggatgtgactgaggtggtccgcaacatgacctctgagttcttcactgcccagctccggtcccagatctctgaccacaccactcacccgatctcctactacaagcccgagttctacacgccggatgacgggggcactgctcacctgtctgtcgtcgcagaggacggcagtgctgtgtccgccaccagcaccatcaacctctactttggctccaaggtctgctccccggtcagtgggatcctgttcaataatgaatggacgacttcagctctcccagcattcaccaatgagtttggggcacccccctcacctgccaatttcatccagccagggaagcagccgctcttgtccatgtgcccgacgatcatggtgggccaggacggccaggtccggatggtggtgggagctgctgggggcacgcagatcaccacagacactgcactggccatcatctacaacctctggttcggctatgacgtgaagagggccgtggaggagccccggctgcacaacaagcttctgcccaacgtcacgacagtggagagaaacattgaccaggcagtgactgcagccctggagacccggcaccatcacacccagatcgcgtccaccttcatcgctgtggtgcaagccatcgtccgcacggctggtggctgggcagctgcctcggactccaggaaaggcggggaacctgctggctactgagtgctccaggcagacaaggctgacaagcaatccagggacaagatactcaccaggatgaggaagaggactttgggggacgggcttcccctgtgagcagcagagcagcataataaatgaggccactgtgccaggctccaggtggcctccctggcctgtctcccca

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