LOCUS       NR_178046               1539 bp    RNA     linear   PRI 30-SEP-2022
DEFINITION  Homo sapiens Zn regulated GTPase metalloprotein activator 1C
            (ZNG1C), transcript variant 6, non-coding, non-coding RNA.
ACCESSION   NR_178046
VERSION     NR_178046.1
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1539)
  AUTHORS   Weiss A, Murdoch CC, Edmonds KA, Jordan MR, Monteith AJ, Perera YR,
            Rodriguez Nassif AM, Petoletti AM, Beavers WN, Munneke MJ, Drury
            SL, Krystofiak ES, Thalluri K, Wu H, Kruse ARS, DiMarchi RD,
            Caprioli RM, Spraggins JM, Chazin WJ, Giedroc DP and Skaar EP.
  TITLE     Zn-regulated GTPase metalloprotein activator 1 modulates vertebrate
            zinc homeostasis
  JOURNAL   Cell 185 (12), 2148-2163 (2022)
   PUBMED   35584702
REFERENCE   2  (bases 1 to 1539)
  AUTHORS   Haenig C, Atias N, Taylor AK, Mazza A, Schaefer MH, Russ J,
            Riechers SP, Jain S, Coughlin M, Fontaine JF, Freibaum BD,
            Brusendorf L, Zenkner M, Porras P, Stroedicke M, Schnoegl S,
            Arnsburg K, Boeddrich A, Pigazzini L, Heutink P, Taylor JP,
            Kirstein J, Andrade-Navarro MA, Sharan R and Wanker EE.
  TITLE     Interactome Mapping Provides a Network of Neurodegenerative Disease
            Proteins and Uncovers Widespread Protein Aggregation in Affected
            Brains
  JOURNAL   Cell Rep 32 (7), 108050 (2020)
   PUBMED   32814053
REFERENCE   3  (bases 1 to 1539)
  AUTHORS   Luck K, Kim DK, Lambourne L, Spirohn K, Begg BE, Bian W, Brignall
            R, Cafarelli T, Campos-Laborie FJ, Charloteaux B, Choi D, Cote AG,
            Daley M, Deimling S, Desbuleux A, Dricot A, Gebbia M, Hardy MF,
            Kishore N, Knapp JJ, Kovacs IA, Lemmens I, Mee MW, Mellor JC,
            Pollis C, Pons C, Richardson AD, Schlabach S, Teeking B, Yadav A,
            Babor M, Balcha D, Basha O, Bowman-Colin C, Chin SF, Choi SG,
            Colabella C, Coppin G, D'Amata C, De Ridder D, De Rouck S,
            Duran-Frigola M, Ennajdaoui H, Goebels F, Goehring L, Gopal A,
            Haddad G, Hatchi E, Helmy M, Jacob Y, Kassa Y, Landini S, Li R, van
            Lieshout N, MacWilliams A, Markey D, Paulson JN, Rangarajan S,
            Rasla J, Rayhan A, Rolland T, San-Miguel A, Shen Y, Sheykhkarimli
            D, Sheynkman GM, Simonovsky E, Tasan M, Tejeda A, Tropepe V,
            Twizere JC, Wang Y, Weatheritt RJ, Weile J, Xia Y, Yang X,
            Yeger-Lotem E, Zhong Q, Aloy P, Bader GD, De Las Rivas J, Gaudet S,
            Hao T, Rak J, Tavernier J, Hill DE, Vidal M, Roth FP and Calderwood
            MA.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   4  (bases 1 to 1539)
  AUTHORS   Oh JH, Yang JO, Hahn Y, Kim MR, Byun SS, Jeon YJ, Kim JM, Song KS,
            Noh SM, Kim S, Yoo HS, Kim YS and Kim NS.
  TITLE     Transcriptome analysis of human gastric cancer
  JOURNAL   Mamm Genome 16 (12), 942-954 (2005)
   PUBMED   16341674
REFERENCE   5  (bases 1 to 1539)
  AUTHORS   Wong A, Vallender EJ, Heretis K, Ilkin Y, Lahn BT, Martin CL and
            Ledbetter DH.
  TITLE     Diverse fates of paralogs following segmental duplication of
            telomeric genes
  JOURNAL   Genomics 84 (2), 239-247 (2004)
   PUBMED   15233989
REFERENCE   6  (bases 1 to 1539)
  AUTHORS   Fan Y, Newman T, Linardopoulou E and Trask BJ.
  TITLE     Gene content and function of the ancestral chromosome fusion site
            in human chromosome 2q13-2q14.1 and paralogous regions
  JOURNAL   Genome Res 12 (11), 1663-1672 (2002)
   PUBMED   12421752
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CP068269.2.
            
            Transcript Variant: This variant (6, non-coding) uses the same exon
            combination as variant (6, coding) but represents the allele
            present on the T2T-CHM13v2.0 genome assembly. This variant is
            represented as non-coding because the use of the 5'-most expected
            translational start codon renders the transcript a candidate for
            nonsense-mediated mRNA decay (NMD).
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR14038194.220633.1,
                                           SRR14038196.3299323.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-203               CP068269.2         80416505-80416707
            204-290             CP068269.2         80419742-80419828
            291-387             CP068269.2         80422145-80422241
            388-479             CP068269.2         80423337-80423428
            480-517             CP068269.2         80433050-80433087
            518-564             CP068269.2         80438986-80439032
            565-609             CP068269.2         80443465-80443509
            610-666             CP068269.2         80448563-80448619
            667-719             CP068269.2         80459670-80459722
            720-788             CP068269.2         80471266-80471334
            789-854             CP068269.2         80471438-80471503
            855-984             CP068269.2         80472650-80472779
            985-1539            CP068269.2         80473167-80473721
FEATURES             Location/Qualifiers
     source          1..1539
                     /organism="Homo sapiens"
                     /mol_type="transcribed RNA"
                     /db_xref="taxon:9606"
                     /chromosome="9"
                     /map="9q21.11"
     gene            1..1539
                     /gene="ZNG1C"
                     /gene_synonym="bA561O23.1; CBWD3"
                     /note="Zn regulated GTPase metalloprotein activator 1C"
                     /db_xref="GeneID:445571"
                     /db_xref="HGNC:HGNC:18519"
                     /db_xref="MIM:611080"
     misc_RNA        1..1539
                     /gene="ZNG1C"
                     /gene_synonym="bA561O23.1; CBWD3"
                     /product="Zn regulated GTPase metalloprotein activator 1C,
                     transcript variant 6, non-coding"
                     /db_xref="GeneID:445571"
                     /db_xref="HGNC:HGNC:18519"
                     /db_xref="MIM:611080"
     exon            1..203
                     /gene="ZNG1C"
                     /gene_synonym="bA561O23.1; CBWD3"
                     /inference="alignment:Splign:2.1.0"
     misc_feature    50..715
                     /gene="ZNG1C"
                     /gene_synonym="bA561O23.1; CBWD3"
                     /inference="COORDINATES:
                     alignment:Blast2seq::RefSeq|NM_201453.4"
                     /note="primary ORF has stop codon >50 nucleotides from the
                     terminal splice site; nonsense-mediated decay (NMD)
                     candidate"
     exon            204..290
                     /gene="ZNG1C"
                     /gene_synonym="bA561O23.1; CBWD3"
                     /inference="alignment:Splign:2.1.0"
     exon            291..387
                     /gene="ZNG1C"
                     /gene_synonym="bA561O23.1; CBWD3"
                     /inference="alignment:Splign:2.1.0"
     exon            388..479
                     /gene="ZNG1C"
                     /gene_synonym="bA561O23.1; CBWD3"
                     /inference="alignment:Splign:2.1.0"
     exon            480..517
                     /gene="ZNG1C"
                     /gene_synonym="bA561O23.1; CBWD3"
                     /inference="alignment:Splign:2.1.0"
     exon            518..564
                     /gene="ZNG1C"
                     /gene_synonym="bA561O23.1; CBWD3"
                     /inference="alignment:Splign:2.1.0"
     exon            565..609
                     /gene="ZNG1C"
                     /gene_synonym="bA561O23.1; CBWD3"
                     /inference="alignment:Splign:2.1.0"
     exon            610..666
                     /gene="ZNG1C"
                     /gene_synonym="bA561O23.1; CBWD3"
                     /inference="alignment:Splign:2.1.0"
     exon            667..719
                     /gene="ZNG1C"
                     /gene_synonym="bA561O23.1; CBWD3"
                     /inference="alignment:Splign:2.1.0"
     exon            720..788
                     /gene="ZNG1C"
                     /gene_synonym="bA561O23.1; CBWD3"
                     /inference="alignment:Splign:2.1.0"
     exon            789..854
                     /gene="ZNG1C"
                     /gene_synonym="bA561O23.1; CBWD3"
                     /inference="alignment:Splign:2.1.0"
     exon            855..984
                     /gene="ZNG1C"
                     /gene_synonym="bA561O23.1; CBWD3"
                     /inference="alignment:Splign:2.1.0"
     exon            985..1539
                     /gene="ZNG1C"
                     /gene_synonym="bA561O23.1; CBWD3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      

gtgttggtcccagcggttcagctgaggtagggacgtgctgtaggccggaatgttaccggctgttggatctgtggatgaggaagaggatcctgcggaggaggattgtcctgaattggttcccattgagacgacgcaaagcgaggaggaggaaaagtctggcctcggcgccaagatcccagtcacaattatcaccgggtatttaggtgctgggaagacaacacttctgaactatattttgacagagcaacatagtaaaagagtagcggtcattttaaatgaatctggggaaggaagtgcgctggagaaatccttagctgtcagccaaggtggagagctctatgaagagtggctggaacttagaaacggttgcctctgctgttcagtgaaggacaatggccttagagctattgagaatttgatgcaaaagaaggggaaatttgattacatactgttagagaccactggattagcagaccctggtatcataactattgtggattcaaaatatggattaaaacatttaacagaagagaaacctgatggccttatcaatgaagctactagatccataaatggactaggacaaatcttagaaacacaaagatcaagagttgatctctctaatgtattagatcttcatgcctttgatagtctctctggaataagtttgcagaaaaaaacttcagcatgtgccaggaacacaacctcaccttgatcagagtattgttacaatcacatttgacgtaccaggaaatgcaaaggaagatcatcttaatatgtttattcagaatcttctgtgggaaaagaatgtgagaaacaaggacaatcactgcatggaggtcataaggctgaagggattggtgtcaatcaaagacaaatcacaacaagtgattgtccagggtgtccatgagctctatgatctggaggagactccagtgagctggaaggatgacactgagagaacaaatcgattggtcctcattggcagaaatttagataaggatatccttaaacagctgtttatagctactgtgacagaaacagaaaagcagtggacaacacatttcaaagaagatcaagtttgtacataacactagaggcatttcttatcaaaaggattggataataaaaataagtttctactgggtatatttcaagcatttatttattactttagttacgaattccaatatactttaaaatggtatttgttttacagcatacataaaatgtagcaaatcagtactgtaaaacatttaacattcatacaattatatataatatccttttttttaaagaatggtatttcacaaaaatatcttttgaaattggctttggagtttacatatactgaacatgaaagtttataataatgatgatacaactttcaacattgtcattttttcttagaacttcagctgattgcagagatataatgattacattgttattaaatttttttaacacaagtaagtgtcaccattttatgacatgaaataaaaggttatgactgttattgatgttgatgttgacgacctg

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