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Previous release (v1)
2026-10-05 20:36:32, GGRNA.v2 : RefSeq release 233 (Jan, 2026)
LOCUS NR_031719 61 bp RNA linear PRI 15-MAY-2022
DEFINITION Homo sapiens microRNA 1538 (MIR1538), microRNA.
ACCESSION NR_031719
VERSION NR_031719.1
KEYWORDS RefSeq.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 61)
AUTHORS Zhang X, Yang Y, Zhang W, Huang K, Xu L, Shahid N, Pan Y, Xu C,
Jiao X and Yang K.
TITLE Downregulation of MiR-1538 promotes proliferation and metastasis of
colorectal cancer by targeting DNMT3A
JOURNAL Biochem Biophys Res Commun 609, 119-126 (2022)
PUBMED 35429679
REMARK GeneRIF: Downregulation of MiR-1538 promotes proliferation and
metastasis of colorectal cancer by targeting DNMT3A.
REFERENCE 2 (bases 1 to 61)
AUTHORS Azuma-Mukai A, Oguri H, Mituyama T, Qian ZR, Asai K, Siomi H and
Siomi MC.
TITLE Characterization of endogenous human Argonautes and their miRNA
partners in RNA silencing
JOURNAL Proc Natl Acad Sci U S A 105 (23), 7964-7969 (2008)
PUBMED 18524951
REFERENCE 3 (bases 1 to 61)
AUTHORS Griffiths-Jones S, Grocock RJ, van Dongen S, Bateman A and Enright
AJ.
TITLE miRBase: microRNA sequences, targets and gene nomenclature
JOURNAL Nucleic Acids Res 34 (Database issue), D140-D144 (2006)
PUBMED 16381832
COMMENT PROVISIONAL REFSEQ: This record is based on preliminary annotation
provided by NCBI staff in collaboration with miRBase. The reference
sequence was derived from AC009032.8.
Summary: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs
that are involved in post-transcriptional regulation of gene
expression in multicellular organisms by affecting both the
stability and translation of mRNAs. miRNAs are transcribed by RNA
polymerase II as part of capped and polyadenylated primary
transcripts (pri-miRNAs) that can be either protein-coding or
non-coding. The primary transcript is cleaved by the Drosha
ribonuclease III enzyme to produce an approximately 70-nt stem-loop
precursor miRNA (pre-miRNA), which is further cleaved by the
cytoplasmic Dicer ribonuclease to generate the mature miRNA and
antisense miRNA star (miRNA*) products. The mature miRNA is
incorporated into a RNA-induced silencing complex (RISC), which
recognizes target mRNAs through imperfect base pairing with the
miRNA and most commonly results in translational inhibition or
destabilization of the target mRNA. The RefSeq represents the
predicted microRNA stem-loop. [provided by RefSeq, Sep 2009].
Sequence Note: This record represents a predicted microRNA
stem-loop as defined by miRBase. Some sequence at the 5' and 3'
ends may not be included in the intermediate precursor miRNA
produced by Drosha cleavage.
PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP
1-61 AC009032.8 67628-67688
FEATURES Location/Qualifiers
source 1..61
/organism="Homo sapiens"
/mol_type="transcribed RNA"
/db_xref="taxon:9606"
/chromosome="16"
/map="16q22.1"
gene 1..61
/gene="MIR1538"
/gene_synonym="hsa-mir-1538; MIRN1538"
/note="microRNA 1538"
/db_xref="GeneID:100302119"
/db_xref="HGNC:HGNC:35382"
/db_xref="miRBase:MI0007259"
precursor_RNA 1..61
/gene="MIR1538"
/gene_synonym="hsa-mir-1538; MIRN1538"
/product="microRNA 1538"
/db_xref="GeneID:100302119"
/db_xref="HGNC:HGNC:35382"
/db_xref="miRBase:MI0007259"
exon 1..61
/gene="MIR1538"
/gene_synonym="hsa-mir-1538; MIRN1538"
/inference="alignment:Splign:2.1.0"
variation 5
/gene="MIR1538"
/gene_synonym="hsa-mir-1538; MIRN1538"
/replace="a"
/replace="t"
/db_xref="dbSNP:2015990264"
variation 6
/gene="MIR1538"
/gene_synonym="hsa-mir-1538; MIRN1538"
/replace="c"
/replace="g"
/db_xref="dbSNP:1597317885"
variation 7
/gene="MIR1538"
/gene_synonym="hsa-mir-1538; MIRN1538"
/replace="a"
/replace="g"
/db_xref="dbSNP:1597317880"
variation 10
/gene="MIR1538"
/gene_synonym="hsa-mir-1538; MIRN1538"
/replace="a"
/replace="g"
/db_xref="dbSNP:1252426259"
variation 12..16
/gene="MIR1538"
/gene_synonym="hsa-mir-1538; MIRN1538"
/replace="ca"
/replace="caaca"
/db_xref="dbSNP:2015989753"
variation 12
/gene="MIR1538"
/gene_synonym="hsa-mir-1538; MIRN1538"
/replace="c"
/replace="t"
/db_xref="dbSNP:1165342808"
variation 13
/gene="MIR1538"
/gene_synonym="hsa-mir-1538; MIRN1538"
/replace="a"
/replace="c"
/db_xref="dbSNP:1028696691"
variation 15..22
/gene="MIR1538"
/gene_synonym="hsa-mir-1538; MIRN1538"
/replace="c"
/replace="catgggcc"
/db_xref="dbSNP:1337644606"
variation 15
/gene="MIR1538"
/gene_synonym="hsa-mir-1538; MIRN1538"
/replace="c"
/replace="g"
/replace="t"
/db_xref="dbSNP:996237540"
variation 16
/gene="MIR1538"
/gene_synonym="hsa-mir-1538; MIRN1538"
/replace="a"
/replace="c"
/replace="g"
/replace="t"
/db_xref="dbSNP:965963740"
variation 17
/gene="MIR1538"
/gene_synonym="hsa-mir-1538; MIRN1538"
/replace="a"
/replace="c"
/replace="g"
/replace="t"
/db_xref="dbSNP:1018800171"
variation 18..20
/gene="MIR1538"
/gene_synonym="hsa-mir-1538; MIRN1538"
/replace="gg"
/replace="ggg"
/db_xref="dbSNP:1317920336"
variation 18
/gene="MIR1538"
/gene_synonym="hsa-mir-1538; MIRN1538"
/replace="a"
/replace="g"
/replace="t"
/db_xref="dbSNP:889676100"
variation 19
/gene="MIR1538"
/gene_synonym="hsa-mir-1538; MIRN1538"
/replace="c"
/replace="g"
/replace="t"
/db_xref="dbSNP:1251768476"
variation 20
/gene="MIR1538"
/gene_synonym="hsa-mir-1538; MIRN1538"
/replace="c"
/replace="g"
/replace="t"
/db_xref="dbSNP:1050122481"
variation 21
/gene="MIR1538"
/gene_synonym="hsa-mir-1538; MIRN1538"
/replace="c"
/replace="t"
/db_xref="dbSNP:549049579"
variation 22
/gene="MIR1538"
/gene_synonym="hsa-mir-1538; MIRN1538"
/replace="c"
/replace="g"
/replace="t"
/db_xref="dbSNP:1266588922"
variation 24
/gene="MIR1538"
/gene_synonym="hsa-mir-1538; MIRN1538"
/replace="a"
/replace="c"
/replace="g"
/replace="t"
/db_xref="dbSNP:886245948"
variation 31
/gene="MIR1538"
/gene_synonym="hsa-mir-1538; MIRN1538"
/replace="a"
/replace="g"
/replace="t"
/db_xref="dbSNP:1487510827"
variation 32
/gene="MIR1538"
/gene_synonym="hsa-mir-1538; MIRN1538"
/replace="a"
/replace="c"
/replace="g"
/replace="t"
/db_xref="dbSNP:1049621441"
variation 34..42
/gene="MIR1538"
/gene_synonym="hsa-mir-1538; MIRN1538"
/replace="cggc"
/replace="cggcgcggc"
/db_xref="dbSNP:2543527218"
variation 34
/gene="MIR1538"
/gene_synonym="hsa-mir-1538; MIRN1538"
/replace="a"
/replace="c"
/replace="g"
/replace="t"
/db_xref="dbSNP:994894154"
variation 35
/gene="MIR1538"
/gene_synonym="hsa-mir-1538; MIRN1538"
/replace="a"
/replace="c"
/replace="g"
/db_xref="dbSNP:905934140"
variation 36
/gene="MIR1538"
/gene_synonym="hsa-mir-1538; MIRN1538"
/replace="a"
/replace="c"
/replace="g"
/db_xref="dbSNP:1597317803"
variation 37
/gene="MIR1538"
/gene_synonym="hsa-mir-1538; MIRN1538"
/replace="a"
/replace="c"
/replace="t"
/db_xref="dbSNP:191393746"
ncRNA 39..61
/ncRNA_class="miRNA"
/gene="MIR1538"
/gene_synonym="hsa-mir-1538; MIRN1538"
/product="hsa-miR-1538"
/db_xref="miRBase:MIMAT0007400"
/db_xref="GeneID:100302119"
/db_xref="HGNC:HGNC:35382"
/db_xref="miRBase:MI0007259"
variation 39
/gene="MIR1538"
/gene_synonym="hsa-mir-1538; MIRN1538"
/replace="a"
/replace="c"
/replace="t"
/db_xref="dbSNP:1268793405"
variation 40
/gene="MIR1538"
/gene_synonym="hsa-mir-1538; MIRN1538"
/replace="c"
/replace="g"
/replace="t"
/db_xref="dbSNP:945480240"
variation 41
/gene="MIR1538"
/gene_synonym="hsa-mir-1538; MIRN1538"
/replace="a"
/replace="g"
/replace="t"
/db_xref="dbSNP:1229814496"
variation 42
/gene="MIR1538"
/gene_synonym="hsa-mir-1538; MIRN1538"
/replace="c"
/replace="t"
/db_xref="dbSNP:2015987934"
variation 43
/gene="MIR1538"
/gene_synonym="hsa-mir-1538; MIRN1538"
/replace="a"
/replace="c"
/replace="t"
/db_xref="dbSNP:950011608"
variation 44
/gene="MIR1538"
/gene_synonym="hsa-mir-1538; MIRN1538"
/replace="a"
/replace="c"
/replace="g"
/replace="t"
/db_xref="dbSNP:376409664"
variation 45
/gene="MIR1538"
/gene_synonym="hsa-mir-1538; MIRN1538"
/replace="a"
/replace="c"
/replace="g"
/db_xref="dbSNP:2015987673"
variation 46
/gene="MIR1538"
/gene_synonym="hsa-mir-1538; MIRN1538"
/replace="a"
/replace="c"
/replace="g"
/replace="t"
/db_xref="dbSNP:1357756517"
variation 47
/gene="MIR1538"
/gene_synonym="hsa-mir-1538; MIRN1538"
/replace="c"
/replace="g"
/db_xref="dbSNP:2015987493"
variation 48
/gene="MIR1538"
/gene_synonym="hsa-mir-1538; MIRN1538"
/replace="c"
/replace="g"
/replace="t"
/db_xref="dbSNP:1312567081"
variation 49
/gene="MIR1538"
/gene_synonym="hsa-mir-1538; MIRN1538"
/replace="c"
/replace="g"
/replace="t"
/db_xref="dbSNP:1302764916"
variation 51
/gene="MIR1538"
/gene_synonym="hsa-mir-1538; MIRN1538"
/replace="c"
/replace="t"
/db_xref="dbSNP:1251934183"
variation 52..55
/gene="MIR1538"
/gene_synonym="hsa-mir-1538; MIRN1538"
/replace="tgct"
/replace="tgcttgct"
/db_xref="dbSNP:2015986844"
variation 52
/gene="MIR1538"
/gene_synonym="hsa-mir-1538; MIRN1538"
/replace="c"
/replace="g"
/replace="t"
/db_xref="dbSNP:1482881000"
variation 53
/gene="MIR1538"
/gene_synonym="hsa-mir-1538; MIRN1538"
/replace="c"
/replace="g"
/replace="t"
/db_xref="dbSNP:917909479"
variation 54
/gene="MIR1538"
/gene_synonym="hsa-mir-1538; MIRN1538"
/replace="a"
/replace="c"
/replace="g"
/replace="t"
/db_xref="dbSNP:1476031503"
variation 55
/gene="MIR1538"
/gene_synonym="hsa-mir-1538; MIRN1538"
/replace="c"
/replace="t"
/db_xref="dbSNP:1188596906"
variation 56
/gene="MIR1538"
/gene_synonym="hsa-mir-1538; MIRN1538"
/replace="a"
/replace="c"
/replace="g"
/replace="t"
/db_xref="dbSNP:1396563161"
variation 58
/gene="MIR1538"
/gene_synonym="hsa-mir-1538; MIRN1538"
/replace="c"
/replace="g"
/replace="t"
/db_xref="dbSNP:1421950418"
variation 59
/gene="MIR1538"
/gene_synonym="hsa-mir-1538; MIRN1538"
/replace="a"
/replace="c"
/db_xref="dbSNP:2015986499"
variation 61
/gene="MIR1538"
/gene_synonym="hsa-mir-1538; MIRN1538"
/replace="a"
/replace="g"
/replace="t"
/db_xref="dbSNP:1056432623"
ORIGIN
gggaacagcagcaacatgggcctcgcttcctgccggcgcggcccgggctgctgctgttcct
//
by
@meso_cacase at
DBCLS
This page is licensed under a
Creative Commons Attribution 4.0 International License (CC BY 4.0).
If you use GGRNA in your work, please cite:
Naito Y, Bono H. (2012)
GGRNA: an ultrafast, transcript-oriented search engine for genes and transcripts.
Nucleic Acids Res., 40, W592-W596.
[Full Text]