2025-10-18 11:41:31, GGRNA.v2 : RefSeq release 232 (Sep, 2025)
LOCUS NR_029489 82 bp RNA linear PRI 11-SEP-2024 DEFINITION Homo sapiens microRNA 19a (MIR19A), microRNA. ACCESSION NR_029489 VERSION NR_029489.1 KEYWORDS RefSeq. SOURCE Homo sapiens (human) ORGANISM Homo sapiens Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. REFERENCE 1 (bases 1 to 82) AUTHORS Luo,J., Wang,L., Cui,C., Chen,H., Zeng,W. and Li,X. TITLE MicroRNA-19a-3p inhibits endothelial dysfunction in atherosclerosis by targeting JCAD JOURNAL BMC Cardiovasc Disord 24 (1), 394 (2024) PUBMED 39080547 REMARK GeneRIF: MicroRNA-19a-3p inhibits endothelial dysfunction in atherosclerosis by targeting JCAD. Publication Status: Online-Only REFERENCE 2 (bases 1 to 82) AUTHORS Fernandez-Sanjurjo,M., Pinto-Hernandez,P., Davalos,A., Diaz-Martinez,A.E., Martin-Hernandez,R., Castilla-Silgado,J., Toyos-Rodriguez,C., Whitham,M., Amado-Rodriguez,L., Muniz-Albaiceta,G., Terrados,N., Fernandez-Garcia,B. and Iglesias-Gutierrez,E. TITLE Next-generation sequencing reveals that miR-16-5p, miR-19a-3p, miR-451a, and miR-25-3p cargo in plasma extracellular vesicles differentiates sedentary young males from athletes JOURNAL Eur J Sport Sci 24 (6), 766-776 (2024) PUBMED 38874986 REMARK GeneRIF: Next-generation sequencing reveals that miR-16-5p, miR-19a-3p, miR-451a, and miR-25-3p cargo in plasma extracellular vesicles differentiates sedentary young males from athletes. REFERENCE 3 (bases 1 to 82) AUTHORS Chen,H., Li,X., Chen,W., Wu,T. and Liu,S. TITLE LncRNA HOTAIR Inhibits miR-19a-3p to Alleviate Foam Cell Formation and Inflammatory Response in Atherosclerosis JOURNAL Int J Med Sci 21 (3), 521-529 (2024) PUBMED 38250607 REMARK GeneRIF: LncRNA HOTAIR Inhibits miR-19a-3p to Alleviate Foam Cell Formation and Inflammatory Response in Atherosclerosis. Publication Status: Online-Only REFERENCE 4 (bases 1 to 82) AUTHORS Yang,X., Luo,Y., Li,M., Jin,Z., Chen,G. and Gan,C. TITLE Long non-coding RNA NBR2 suppresses the progression of colorectal cancer by downregulating miR-19a to regulate M2 macrophage polarization JOURNAL Chin J Physiol 66 (6), 546-557 (2023) PUBMED 38149567 REMARK GeneRIF: Long non-coding RNA NBR2 suppresses the progression of colorectal cancer by downregulating miR-19a to regulate M2 macrophage polarization. REFERENCE 5 (bases 1 to 82) AUTHORS Du,L., Dou,K., Zhang,D., Xia,H., Liang,N., Wang,N., Sun,J. and Bai,R. TITLE MiR-19a-3p Promotes Aerobic Glycolysis in Ovarian Cancer Cells via IGFBP3/PI3K/AKT Pathway JOURNAL Folia Biol (Praha) 69 (5-6), 163-172 (2023) PUBMED 38583177 REMARK GeneRIF: MiR-19a-3p Promotes Aerobic Glycolysis in Ovarian Cancer Cells via IGFBP3/PI3K/AKT Pathway. REFERENCE 6 (bases 1 to 82) AUTHORS Griffiths-Jones,S., Grocock,R.J., van Dongen,S., Bateman,A. and Enright,A.J. TITLE miRBase: microRNA sequences, targets and gene nomenclature JOURNAL Nucleic Acids Res 34 (Database issue), D140-D144 (2006) PUBMED 16381832 REFERENCE 7 (bases 1 to 82) AUTHORS Ota,A., Tagawa,H., Karnan,S., Tsuzuki,S., Karpas,A., Kira,S., Yoshida,Y. and Seto,M. TITLE Identification and characterization of a novel gene, C13orf25, as a target for 13q31-q32 amplification in malignant lymphoma JOURNAL Cancer Res 64 (9), 3087-3095 (2004) PUBMED 15126345 REFERENCE 8 (bases 1 to 82) AUTHORS Dostie,J., Mourelatos,Z., Yang,M., Sharma,A. and Dreyfuss,G. TITLE Numerous microRNPs in neuronal cells containing novel microRNAs JOURNAL RNA 9 (2), 180-186 (2003) PUBMED 12554860 REMARK Erratum:[RNA. 2003 May;9(5):631-2] REFERENCE 9 (bases 1 to 82) AUTHORS Mourelatos,Z., Dostie,J., Paushkin,S., Sharma,A., Charroux,B., Abel,L., Rappsilber,J., Mann,M. and Dreyfuss,G. TITLE miRNPs: a novel class of ribonucleoproteins containing numerous microRNAs JOURNAL Genes Dev 16 (6), 720-728 (2002) PUBMED 11914277 REFERENCE 10 (bases 1 to 82) AUTHORS Lagos-Quintana,M., Rauhut,R., Lendeckel,W. and Tuschl,T. TITLE Identification of novel genes coding for small expressed RNAs JOURNAL Science 294 (5543), 853-858 (2001) PUBMED 11679670 COMMENT PROVISIONAL REFSEQ: This record is based on preliminary annotation provided by NCBI staff in collaboration with miRBase. The reference sequence was derived from AL162375.24. This sequence is a reference standard in the RefSeqGene project. Summary: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]. Sequence Note: This record represents a predicted microRNA stem-loop as defined by miRBase. Some sequence at the 5' and 3' ends may not be included in the intermediate precursor miRNA produced by Drosha cleavage. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript is intronless :: LM608162.1 [ECO:0000345] ##Evidence-Data-END## PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-82 AL162375.24 23217-23298 FEATURES Location/Qualifiers source 1..82 /organism="Homo sapiens" /mol_type="transcribed RNA" /db_xref="taxon:9606" /chromosome="13" /map="13q31.3" gene 1..82 /gene="MIR19A" /gene_synonym="C13orf25; hsa-mir-19a; miR-19a; MIR17HG; MIRH1; MIRHG1; MIRN19A; miRNA19A" /note="microRNA 19a" /db_xref="GeneID:406979" /db_xref="HGNC:HGNC:31574" /db_xref="MIM:609418" /db_xref="miRBase:MI0000073" precursor_RNA 1..82 /gene="MIR19A" /gene_synonym="C13orf25; hsa-mir-19a; miR-19a; MIR17HG; MIRH1; MIRHG1; MIRN19A; miRNA19A" /product="microRNA 19a" /db_xref="GeneID:406979" /db_xref="HGNC:HGNC:31574" /db_xref="MIM:609418" /db_xref="miRBase:MI0000073" exon 1..82 /gene="MIR19A" /gene_synonym="C13orf25; hsa-mir-19a; miR-19a; MIR17HG; MIRH1; MIRHG1; MIRN19A; miRNA19A" /inference="alignment:Splign:2.1.0" variation 1 /gene="MIR19A" /gene_synonym="C13orf25; hsa-mir-19a; miR-19a; MIR17HG; MIRH1; MIRHG1; MIRN19A; miRNA19A" /replace="a" /replace="g" /db_xref="dbSNP:1594014031" variation 2 /gene="MIR19A" /gene_synonym="C13orf25; hsa-mir-19a; miR-19a; MIR17HG; MIRH1; MIRHG1; MIRN19A; miRNA19A" /replace="c" /replace="t" /db_xref="dbSNP:750595412" variation 6 /gene="MIR19A" /gene_synonym="C13orf25; hsa-mir-19a; miR-19a; MIR17HG; MIRH1; MIRHG1; MIRN19A; miRNA19A" /replace="c" /replace="t" /db_xref="dbSNP:2501246793" variation 7..10 /gene="MIR19A" /gene_synonym="C13orf25; hsa-mir-19a; miR-19a; MIR17HG; MIRH1; MIRHG1; MIRN19A; miRNA19A" /replace="ct" /replace="ctct" /db_xref="dbSNP:761092550" variation 7 /gene="MIR19A" /gene_synonym="C13orf25; hsa-mir-19a; miR-19a; MIR17HG; MIRH1; MIRHG1; MIRN19A; miRNA19A" /replace="a" /replace="c" /replace="t" /db_xref="dbSNP:1477297925" variation 9 /gene="MIR19A" /gene_synonym="C13orf25; hsa-mir-19a; miR-19a; MIR17HG; MIRH1; MIRHG1; MIRN19A; miRNA19A" /replace="c" /replace="t" /db_xref="dbSNP:1168187778" variation 10..12 /gene="MIR19A" /gene_synonym="C13orf25; hsa-mir-19a; miR-19a; MIR17HG; MIRH1; MIRHG1; MIRN19A; miRNA19A" /replace="t" /replace="tgt" /db_xref="dbSNP:1875275146" variation 10 /gene="MIR19A" /gene_synonym="C13orf25; hsa-mir-19a; miR-19a; MIR17HG; MIRH1; MIRHG1; MIRN19A; miRNA19A" /replace="g" /replace="t" /db_xref="dbSNP:2501246842" ncRNA 14..35 /ncRNA_class="miRNA" /gene="MIR19A" /gene_synonym="C13orf25; hsa-mir-19a; miR-19a; MIR17HG; MIRH1; MIRHG1; MIRN19A; miRNA19A" /product="hsa-miR-19a-5p" /db_xref="miRBase:MIMAT0004490" /db_xref="GeneID:406979" /db_xref="HGNC:HGNC:31574" /db_xref="MIM:609418" /db_xref="miRBase:MI0000073" variation 14 /gene="MIR19A" /gene_synonym="C13orf25; hsa-mir-19a; miR-19a; MIR17HG; MIRH1; MIRHG1; MIRN19A; miRNA19A" /replace="a" /replace="c" /replace="g" /db_xref="dbSNP:1875275359" variation 15 /gene="MIR19A" /gene_synonym="C13orf25; hsa-mir-19a; miR-19a; MIR17HG; MIRH1; MIRHG1; MIRN19A; miRNA19A" /replace="a" /replace="g" /db_xref="dbSNP:756288295" variation 16 /gene="MIR19A" /gene_synonym="C13orf25; hsa-mir-19a; miR-19a; MIR17HG; MIRH1; MIRHG1; MIRN19A; miRNA19A" /replace="a" /replace="t" /db_xref="dbSNP:1566344357" variation 18 /gene="MIR19A" /gene_synonym="C13orf25; hsa-mir-19a; miR-19a; MIR17HG; MIRH1; MIRHG1; MIRN19A; miRNA19A" /replace="c" /replace="t" /db_xref="dbSNP:1875275939" variation 19 /gene="MIR19A" /gene_synonym="C13orf25; hsa-mir-19a; miR-19a; MIR17HG; MIRH1; MIRHG1; MIRN19A; miRNA19A" /replace="c" /replace="t" /db_xref="dbSNP:1051963210" variation 20 /gene="MIR19A" /gene_synonym="C13orf25; hsa-mir-19a; miR-19a; MIR17HG; MIRH1; MIRHG1; MIRN19A; miRNA19A" /replace="g" /replace="t" /db_xref="dbSNP:1875276298" variation 21 /gene="MIR19A" /gene_synonym="C13orf25; hsa-mir-19a; miR-19a; MIR17HG; MIRH1; MIRHG1; MIRN19A; miRNA19A" /replace="c" /replace="t" /db_xref="dbSNP:780315531" variation 22 /gene="MIR19A" /gene_synonym="C13orf25; hsa-mir-19a; miR-19a; MIR17HG; MIRH1; MIRHG1; MIRN19A; miRNA19A" /replace="a" /replace="g" /db_xref="dbSNP:1162564162" variation 24 /gene="MIR19A" /gene_synonym="C13orf25; hsa-mir-19a; miR-19a; MIR17HG; MIRH1; MIRHG1; MIRN19A; miRNA19A" /replace="a" /replace="g" /db_xref="dbSNP:2501246925" variation 26 /gene="MIR19A" /gene_synonym="C13orf25; hsa-mir-19a; miR-19a; MIR17HG; MIRH1; MIRHG1; MIRN19A; miRNA19A" /replace="c" /replace="t" /db_xref="dbSNP:1170543143" variation 28 /gene="MIR19A" /gene_synonym="C13orf25; hsa-mir-19a; miR-19a; MIR17HG; MIRH1; MIRHG1; MIRN19A; miRNA19A" /replace="c" /replace="g" /db_xref="dbSNP:1388542964" variation 31 /gene="MIR19A" /gene_synonym="C13orf25; hsa-mir-19a; miR-19a; MIR17HG; MIRH1; MIRHG1; MIRN19A; miRNA19A" /replace="c" /replace="g" /replace="t" /db_xref="dbSNP:1442807536" variation 33 /gene="MIR19A" /gene_synonym="C13orf25; hsa-mir-19a; miR-19a; MIR17HG; MIRH1; MIRHG1; MIRN19A; miRNA19A" /replace="a" /replace="c" /db_xref="dbSNP:1403138754" variation 35..42 /gene="MIR19A" /gene_synonym="C13orf25; hsa-mir-19a; miR-19a; MIR17HG; MIRH1; MIRHG1; MIRN19A; miRNA19A" /replace="aagaa" /replace="aagaagaa" /db_xref="dbSNP:764765453" variation 36 /gene="MIR19A" /gene_synonym="C13orf25; hsa-mir-19a; miR-19a; MIR17HG; MIRH1; MIRHG1; MIRN19A; miRNA19A" /replace="a" /replace="g" /replace="t" /db_xref="dbSNP:1341300736" variation 38 /gene="MIR19A" /gene_synonym="C13orf25; hsa-mir-19a; miR-19a; MIR17HG; MIRH1; MIRHG1; MIRN19A; miRNA19A" /replace="a" /replace="t" /db_xref="dbSNP:2501247020" variation 40 /gene="MIR19A" /gene_synonym="C13orf25; hsa-mir-19a; miR-19a; MIR17HG; MIRH1; MIRHG1; MIRN19A; miRNA19A" /replace="c" /replace="g" /db_xref="dbSNP:2501247031" variation 46 /gene="MIR19A" /gene_synonym="C13orf25; hsa-mir-19a; miR-19a; MIR17HG; MIRH1; MIRHG1; MIRN19A; miRNA19A" /replace="a" /replace="g" /db_xref="dbSNP:1399638017" variation 47 /gene="MIR19A" /gene_synonym="C13orf25; hsa-mir-19a; miR-19a; MIR17HG; MIRH1; MIRHG1; MIRN19A; miRNA19A" /replace="a" /replace="g" /db_xref="dbSNP:2501247050" ncRNA 49..71 /ncRNA_class="miRNA" /gene="MIR19A" /gene_synonym="C13orf25; hsa-mir-19a; miR-19a; MIR17HG; MIRH1; MIRHG1; MIRN19A; miRNA19A" /product="hsa-miR-19a-3p" /db_xref="miRBase:MIMAT0000073" /db_xref="GeneID:406979" /db_xref="HGNC:HGNC:31574" /db_xref="MIM:609418" /db_xref="miRBase:MI0000073" variation 49 /gene="MIR19A" /gene_synonym="C13orf25; hsa-mir-19a; miR-19a; MIR17HG; MIRH1; MIRHG1; MIRN19A; miRNA19A" /replace="g" /replace="t" /db_xref="dbSNP:750154321" variation 51..66 /gene="MIR19A" /gene_synonym="C13orf25; hsa-mir-19a; miR-19a; MIR17HG; MIRH1; MIRHG1; MIRN19A; miRNA19A" /replace="tgcaaa" /replace="tgcaaatctatgcaaa" /db_xref="dbSNP:2501247069" variation 52 /gene="MIR19A" /gene_synonym="C13orf25; hsa-mir-19a; miR-19a; MIR17HG; MIRH1; MIRHG1; MIRN19A; miRNA19A" /replace="a" /replace="g" /db_xref="dbSNP:749350150" variation 53 /gene="MIR19A" /gene_synonym="C13orf25; hsa-mir-19a; miR-19a; MIR17HG; MIRH1; MIRHG1; MIRN19A; miRNA19A" /replace="c" /replace="g" /db_xref="dbSNP:1875278335" variation 55 /gene="MIR19A" /gene_synonym="C13orf25; hsa-mir-19a; miR-19a; MIR17HG; MIRH1; MIRHG1; MIRN19A; miRNA19A" /replace="a" /replace="g" /db_xref="dbSNP:890231900" variation 58 /gene="MIR19A" /gene_synonym="C13orf25; hsa-mir-19a; miR-19a; MIR17HG; MIRH1; MIRHG1; MIRN19A; miRNA19A" /replace="c" /replace="g" /replace="t" /db_xref="dbSNP:1323869733" variation 60 /gene="MIR19A" /gene_synonym="C13orf25; hsa-mir-19a; miR-19a; MIR17HG; MIRH1; MIRHG1; MIRN19A; miRNA19A" /replace="a" /replace="g" /db_xref="dbSNP:1182598123" variation 67 /gene="MIR19A" /gene_synonym="C13orf25; hsa-mir-19a; miR-19a; MIR17HG; MIRH1; MIRHG1; MIRN19A; miRNA19A" /replace="a" /replace="c" /db_xref="dbSNP:755092873" variation 68 /gene="MIR19A" /gene_synonym="C13orf25; hsa-mir-19a; miR-19a; MIR17HG; MIRH1; MIRHG1; MIRN19A; miRNA19A" /replace="c" /replace="g" /db_xref="dbSNP:1265327793" variation 70 /gene="MIR19A" /gene_synonym="C13orf25; hsa-mir-19a; miR-19a; MIR17HG; MIRH1; MIRHG1; MIRN19A; miRNA19A" /replace="a" /replace="g" /db_xref="dbSNP:778783279" variation 71 /gene="MIR19A" /gene_synonym="C13orf25; hsa-mir-19a; miR-19a; MIR17HG; MIRH1; MIRHG1; MIRN19A; miRNA19A" /replace="a" /replace="g" /replace="t" /db_xref="dbSNP:748058730" variation 72..77 /gene="MIR19A" /gene_synonym="C13orf25; hsa-mir-19a; miR-19a; MIR17HG; MIRH1; MIRHG1; MIRN19A; miRNA19A" /replace="tgg" /replace="tggtgg" /db_xref="dbSNP:1875279684" variation 72 /gene="MIR19A" /gene_synonym="C13orf25; hsa-mir-19a; miR-19a; MIR17HG; MIRH1; MIRHG1; MIRN19A; miRNA19A" /replace="a" /replace="c" /replace="t" /db_xref="dbSNP:771832462" variation 77 /gene="MIR19A" /gene_synonym="C13orf25; hsa-mir-19a; miR-19a; MIR17HG; MIRH1; MIRHG1; MIRN19A; miRNA19A" /replace="a" /replace="g" /db_xref="dbSNP:772879142" variation 78 /gene="MIR19A" /gene_synonym="C13orf25; hsa-mir-19a; miR-19a; MIR17HG; MIRH1; MIRHG1; MIRN19A; miRNA19A" /replace="c" /replace="t" /db_xref="dbSNP:993053169" variation 80 /gene="MIR19A" /gene_synonym="C13orf25; hsa-mir-19a; miR-19a; MIR17HG; MIRH1; MIRHG1; MIRN19A; miRNA19A" /replace="c" /replace="t" /db_xref="dbSNP:1257895319" variation 82 /gene="MIR19A" /gene_synonym="C13orf25; hsa-mir-19a; miR-19a; MIR17HG; MIRH1; MIRHG1; MIRN19A; miRNA19A" /replace="c" /replace="g" /replace="t" /db_xref="dbSNP:374554651" ORIGIN
gcagtcctctgttagttttgcatagttgcactacaagaagaatgtagttgtgcaaatctatgcaaaactgatggtggcctgc
//
by
@meso_cacase at
DBCLS
This page is licensed under a
Creative Commons Attribution 4.0 International License (CC BY 4.0).
If you use GGRNA in your work, please cite:
Naito Y, Bono H. (2012)
GGRNA: an ultrafast, transcript-oriented search engine for genes and transcripts.
Nucleic Acids Res., 40, W592-W596.
[Full Text]