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Previous release (v1)
2024-04-28 08:14:27, GGRNA.v2 : RefSeq release 222 (Jan, 2024)
LOCUS NM_001406511 6652 bp mRNA linear PRI 12-DEC-2023
DEFINITION Homo sapiens ATPase copper transporting beta (ATP7B), transcript
variant 6, mRNA.
ACCESSION NM_001406511 XM_005266430
VERSION NM_001406511.1
KEYWORDS RefSeq.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 6652)
AUTHORS Ruturaj, Mishra M, Saha S, Maji S, Rodriguez-Boulan E, Schreiner R
and Gupta A.
TITLE Regulation of the apico-basolateral trafficking polarity of the
homologous copper-ATPases ATP7A and ATP7B
JOURNAL J Cell Sci 137 (5) (2024)
PUBMED 38032054
REMARK GeneRIF: Regulation of the apico-basolateral trafficking polarity
of the homologous copper-ATPases ATP7A and ATP7B.
REFERENCE 2 (bases 1 to 6652)
AUTHORS Gorukmez O, Ozgur T, Gorukmez O and Topak A.
TITLE ATP7B Gene Variant Profile Identified by NGS in Wilson's Disease
JOURNAL Fetal Pediatr Pathol 42 (6), 891-900 (2023)
PUBMED 37737146
REMARK GeneRIF: ATP7B Gene Variant Profile Identified by NGS in Wilson's
Disease.
REFERENCE 3 (bases 1 to 6652)
AUTHORS Chakraborty K, Das S, Pal A, Maji S, Rai B, Gupta A and
Bhattacharjee A.
TITLE Wilson disease-causing mutations in the carboxyl terminus of ATP7B
regulates its localization and Golgi exit selectively in the
unpolarized cells
JOURNAL Metallomics 15 (9) (2023)
PUBMED 37660282
REMARK GeneRIF: Wilson disease-causing mutations in the carboxyl terminus
of ATP7B regulates its localization and Golgi exit selectively in
the unpolarized cells.
REFERENCE 4 (bases 1 to 6652)
AUTHORS Xue Z, Chen H, Yu L and Jiang P.
TITLE A Systematic Review and Meta-Analysis of the R778L Mutation in
ATP7B With Wilson Disease in China
JOURNAL Pediatr Neurol 145, 135-147 (2023)
PUBMED 37354629
REMARK GeneRIF: A Systematic Review and Meta-Analysis of the R778L
Mutation in ATP7B With Wilson Disease in China.
REFERENCE 5 (bases 1 to 6652)
AUTHORS Petrukhin K, Lutsenko S, Chernov I, Ross BM, Kaplan JH and Gilliam
TC.
TITLE Characterization of the Wilson disease gene encoding a P-type
copper transporting ATPase: genomic organization, alternative
splicing, and structure/function predictions
JOURNAL Hum Mol Genet 3 (9), 1647-1656 (1994)
PUBMED 7833924
REFERENCE 6 (bases 1 to 6652)
AUTHORS Petrukhin K, Fischer SG, Pirastu M, Tanzi RE, Chernov I, Devoto M,
Brzustowicz LM, Cayanis E, Vitale E, Russo JJ et al.
TITLE Mapping, cloning and genetic characterization of the region
containing the Wilson disease gene
JOURNAL Nat Genet 5 (4), 338-343 (1993)
PUBMED 8298640
REFERENCE 7 (bases 1 to 6652)
AUTHORS Bull PC, Thomas GR, Rommens JM, Forbes JR and Cox DW.
TITLE The Wilson disease gene is a putative copper transporting P-type
ATPase similar to the Menkes gene
JOURNAL Nat Genet 5 (4), 327-337 (1993)
PUBMED 8298639
REMARK Erratum:[Nat Genet 1994 Feb;6(2):214]
REFERENCE 8 (bases 1 to 6652)
AUTHORS Yamaguchi Y, Heiny ME and Gitlin JD.
TITLE Isolation and characterization of a human liver cDNA as a candidate
gene for Wilson disease
JOURNAL Biochem Biophys Res Commun 197 (1), 271-277 (1993)
PUBMED 8250934
REFERENCE 9 (bases 1 to 6652)
AUTHORS Weiss,K.H. and Schilsky,M.
TITLE Wilson Disease
JOURNAL (in) Adam MP, Feldman J, Mirzaa GM, Pagon RA, Wallace SE, Bean LJH,
Gripp KW and Amemiya A (Eds.);
GENEREVIEWS(R);
(1993)
PUBMED 20301685
REFERENCE 10 (bases 1 to 6652)
AUTHORS Klein,C., Lohmann,K., Marras,C. and Munchau,A.
TITLE Hereditary Dystonia Overview
JOURNAL (in) Adam MP, Feldman J, Mirzaa GM, Pagon RA, Wallace SE, Bean LJH,
Gripp KW and Amemiya A (Eds.);
GENEREVIEWS(R);
(1993)
PUBMED 20301334
COMMENT REVIEWED REFSEQ: This record has been curated by NCBI staff. The
reference sequence was derived from AL139082.18, AL138821.12 and
AL162377.10.
On May 17, 2022 this sequence version replaced XM_005266430.5.
Summary: This gene is a member of the P-type cation transport
ATPase family and encodes a protein with several membrane-spanning
domains, an ATPase consensus sequence, a hinge domain, a
phosphorylation site, and at least 2 putative copper-binding sites.
This protein is a monomer, and functions as a copper-transporting
ATPase which exports copper out of the cells, such as the efflux of
hepatic copper into the bile. Alternate transcriptional splice
variants, encoding different isoforms with distinct cellular
localizations, have been characterized. Mutations in this gene have
been associated with Wilson disease which is characterized by
copper accumulation. [provided by RefSeq, Dec 2019].
Publication Note: This RefSeq record includes a subset of the
publications that are available for this gene. Please see the Gene
record to access additional publications.
##Evidence-Data-START##
Transcript exon combination :: SRR18074969.3649111.1,
SRR18074967.1112693.1 [ECO:0000332]
RNAseq introns :: mixed sample support SAMEA1965299,
SAMEA1966682 [ECO:0006172]
##Evidence-Data-END##
PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP
1-113 AL139082.18 30483-30595 c
114-218 AL139082.18 29750-29854 c
219-1452 AL138821.12 33967-35200 c
1453-1710 AL138821.12 30524-30781 c
1711-1874 AL138821.12 28476-28639 c
1875-2036 AL138821.12 24904-25065 c
2037-2113 AL138821.12 21869-21945 c
2114-2288 AL138821.12 20180-20354 c
2289-2522 AL138821.12 18343-18576 c
2523-2614 AL138821.12 17548-17639 c
2615-2742 AL138821.12 10304-10431 c
2743-2897 AL138821.12 10039-10193 c
2898-3032 AL138821.12 9694-9828 c
3033-3227 AL138821.12 6316-6510 c
3228-3410 AL138821.12 4141-4323 c
3411-3579 AL138821.12 2418-2586 c
3580-3723 AL138821.12 1113-1256 c
3724-3866 AL162377.10 168087-168229 c
3867-4070 AL162377.10 166512-166715 c
4071-4188 AL162377.10 166312-166429 c
4189-4291 AL162377.10 164629-164731 c
4292-6652 AL162377.10 161705-164065 c
FEATURES Location/Qualifiers
source 1..6652
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="13"
/map="13q14.3"
gene 1..6652
/gene="ATP7B"
/gene_synonym="PWD; WC1; WD; WND"
/note="ATPase copper transporting beta"
/db_xref="GeneID:540"
/db_xref="HGNC:HGNC:870"
/db_xref="MIM:606882"
exon 1..113
/gene="ATP7B"
/gene_synonym="PWD; WC1; WD; WND"
/inference="alignment:Splign:2.1.0"
exon 114..218
/gene="ATP7B"
/gene_synonym="PWD; WC1; WD; WND"
/inference="alignment:Splign:2.1.0"
CDS 168..4565
/gene="ATP7B"
/gene_synonym="PWD; WC1; WD; WND"
/EC_number="7.2.2.8"
/note="isoform a is encoded by transcript variant 6;
copper-transporting ATPase 2; copper pump 2; ATPase, Cu++
transporting, beta polypeptide; Wilson disease-associated
protein; ATPase, Cu(2+)- transporting, beta polypeptide;
copper-transporting protein ATP7B"
/codon_start=1
/product="copper-transporting ATPase 2 isoform a"
/protein_id="NP_001393440.1"
/db_xref="CCDS:CCDS41892.1"
/db_xref="GeneID:540"
/db_xref="HGNC:HGNC:870"
/db_xref="MIM:606882"
/translation="
MPEQERQITAREGASRKILSKLSLPTRAWEPAMKKSFAFDNVGYEGGLDGLGPSSQVATSTVRILGMTCQSCVKSIEDRISNLKGIISMKVSLEQGSATVKYVPSVVCLQQVCHQIGDMGFEASIAEGKAASWPSRSLPAQEAVVKLRVEGMTCQSCVSSIEGKVRKLQGVVRVKVSLSNQEAVITYQPYLIQPEDLRDHVNDMGFEAAIKSKVAPLSLGPIDIERLQSTNPKRPLSSANQNFNNSETLGHQGSHVVTLQLRIDGMHCKSCVLNIEENIGQLLGVQSIQVSLENKTAQVKYDPSCTSPVALQRAIEALPPGNFKVSLPDGAEGSGTDHRSSSSHSPGSPPRNQVQGTCSTTLIAIAGMTCASCVHSIEGMISQLEGVQQISVSLAEGTATVLYNPSVISPEELRAAIEDMGFEASVVSESCSTNPLGNHSAGNSMVQTTDGTPTSVQEVAPHTGRLPANHAPDILAKSPQSTRAVAPQKCFLQIKGMTCASCVSNIERNLQKEAGVLSVLVALMAGKAEIKYDPEVIQPLEIAQFIQDLGFEAAVMEDYAGSDGNIELTITGMTCASCVHNIESKLTRTNGITYASVALATSKALVKFDPEIIGPRDIIKIIEEIGFHASLAQRNPNAHHLDHKMEIKQWKKSFLCSLVFGIPVMALMIYMLIPSNEPHQSMVLDHNIIPGLSILNLIFFILCTFVQLLGGWYFYVQAYKSLRHRSANMDVLIVLATSIAYVYSLVILVVAVAEKAERSPVTFFDTPPMLFVFIALGRWLEHLAKSKTSEALAKLMSLQATEATVVTLGEDNLIIREEQVPMELVQRGDIVKVVPGGKFPVDGKVLEGNTMADESLITGEAMPVTKKPGSTVIAGSINAHGSVLIKATHVGNDTTLAQIVKLVEEAQMSKAPIQQLADRFSGYFVPFIIIMSTLTLVVWIVIGFIDFGVVQRYFPNPNKHISQTEVIIRFAFQTSITVLCIACPCSLGLATPTAVMVGTGVAAQNGILIKGGKPLEMAHKIKTVMFDKTGTITHGVPRVMRVLLLGDVATLPLRKVLAVVGTAEASSEHPLGVAVTKYCKEELGTETLGYCTDFQAVPGCGIGCKVSNVEGILAHSERPLSAPASHLNEAGSLPAEKDAVPQTFSVLIGNREWLRRNGLTISSDVSDAMTDHEMKGQTAILVAIDGVLCGMIAIADAVKQEAALAVHTLQSMGVDVVLITGDNRKTARAIATQVGINKVFAEVLPSHKVAKVQELQNKGKKVAMVGDGVNDSPALAQADMGVAIGTGTDVAIEAADVVLIRNDLLDVVASIHLSKRTVRRIRINLVLALIYNLVGIPIAAGVFMPIGIVLQPWMGSAAMAASSVSVVLSSLQLKCYKKPDLERYEAQAHGHMKPLTASQVSVHIGMDDRWRDSPRATPWDQVSYVSQVSLSSLTSDKPSRHSAAADDDGDKWSLLLNGRDEEQYI"
misc_feature 234..236
/gene="ATP7B"
/gene_synonym="PWD; WC1; WD; WND"
/note="Phosphoserine.
/evidence=ECO:0007744|PubMed:23186163; propagated from
UniProtKB/Swiss-Prot (P35670.4); phosphorylation site"
misc_feature 348..539
/gene="ATP7B"
/gene_synonym="PWD; WC1; WD; WND"
/note="Heavy-metal-associated domain (HMA) is a conserved
domain of approximately 30 amino acid residues found in a
number of proteins that transport or detoxify heavy
metals, for example, the CPx-type heavy metal ATPases and
copper chaperones. HMA domain...; Region: HMA; cd00371"
/db_xref="CDD:238219"
misc_feature order(366..374,381..383)
/gene="ATP7B"
/gene_synonym="PWD; WC1; WD; WND"
/note="metal-binding site [ion binding]"
/db_xref="CDD:238219"
misc_feature 603..794
/gene="ATP7B"
/gene_synonym="PWD; WC1; WD; WND"
/note="Heavy-metal-associated domain (HMA) is a conserved
domain of approximately 30 amino acid residues found in a
number of proteins that transport or detoxify heavy
metals, for example, the CPx-type heavy metal ATPases and
copper chaperones. HMA domain...; Region: HMA; cd00371"
/db_xref="CDD:238219"
misc_feature order(621..629,636..638)
/gene="ATP7B"
/gene_synonym="PWD; WC1; WD; WND"
/note="metal-binding site [ion binding]"
/db_xref="CDD:238219"
misc_feature 855..914
/gene="ATP7B"
/gene_synonym="PWD; WC1; WD; WND"
/note="propagated from UniProtKB/Swiss-Prot (P35670.4);
Region: Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite"
misc_feature 945..1121
/gene="ATP7B"
/gene_synonym="PWD; WC1; WD; WND"
/note="Heavy-metal-associated domain (HMA) is a conserved
domain of approximately 30 amino acid residues found in a
number of proteins that transport or detoxify heavy
metals, for example, the CPx-type heavy metal ATPases and
copper chaperones. HMA domain...; Region: HMA; cd00371"
/db_xref="CDD:238219"
misc_feature order(963..971,978..980)
/gene="ATP7B"
/gene_synonym="PWD; WC1; WD; WND"
/note="metal-binding site [ion binding]"
/db_xref="CDD:238219"
misc_feature 1131..1232
/gene="ATP7B"
/gene_synonym="PWD; WC1; WD; WND"
/note="propagated from UniProtKB/Swiss-Prot (P35670.4);
Region: Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite"
misc_feature 1254..1442
/gene="ATP7B"
/gene_synonym="PWD; WC1; WD; WND"
/note="Heavy-metal-associated domain (HMA) is a conserved
domain of approximately 30 amino acid residues found in a
number of proteins that transport or detoxify heavy
metals, for example, the CPx-type heavy metal ATPases and
copper chaperones. HMA domain...; Region: HMA; cd00371"
/db_xref="CDD:238219"
misc_feature order(1269..1277,1284..1286)
/gene="ATP7B"
/gene_synonym="PWD; WC1; WD; WND"
/note="metal-binding site [ion binding]"
/db_xref="CDD:238219"
misc_feature 1599..1601
/gene="ATP7B"
/gene_synonym="PWD; WC1; WD; WND"
/note="Phosphoserine.
/evidence=ECO:0007744|PubMed:23186163; propagated from
UniProtKB/Swiss-Prot (P35670.4); phosphorylation site"
misc_feature 1608..1610
/gene="ATP7B"
/gene_synonym="PWD; WC1; WD; WND"
/note="Phosphoserine.
/evidence=ECO:0000250|UniProtKB:Q64535; propagated from
UniProtKB/Swiss-Prot (P35670.4); phosphorylation site"
misc_feature 1641..1829
/gene="ATP7B"
/gene_synonym="PWD; WC1; WD; WND"
/note="Heavy-metal-associated domain (HMA) is a conserved
domain of approximately 30 amino acid residues found in a
number of proteins that transport or detoxify heavy
metals, for example, the CPx-type heavy metal ATPases and
copper chaperones. HMA domain...; Region: HMA; cd00371"
/db_xref="CDD:238219"
misc_feature order(1656..1664,1671..1673)
/gene="ATP7B"
/gene_synonym="PWD; WC1; WD; WND"
/note="metal-binding site [ion binding]"
/db_xref="CDD:238219"
misc_feature 1866..2057
/gene="ATP7B"
/gene_synonym="PWD; WC1; WD; WND"
/note="Heavy-metal-associated domain (HMA) is a conserved
domain of approximately 30 amino acid residues found in a
number of proteins that transport or detoxify heavy
metals, for example, the CPx-type heavy metal ATPases and
copper chaperones. HMA domain...; Region: HMA; cd00371"
/db_xref="CDD:238219"
misc_feature order(1884..1892,1899..1901)
/gene="ATP7B"
/gene_synonym="PWD; WC1; WD; WND"
/note="metal-binding site [ion binding]"
/db_xref="CDD:238219"
misc_feature 2121..4229
/gene="ATP7B"
/gene_synonym="PWD; WC1; WD; WND"
/note="P-type heavy metal-transporting ATPase, similar to
human copper-transporting ATPases, ATP7A and ATP7B;
Region: P-type_ATPase_Cu-like; cd02094"
/db_xref="CDD:319783"
misc_feature 2127..2192
/gene="ATP7B"
/gene_synonym="PWD; WC1; WD; WND"
/note="propagated from UniProtKB/Swiss-Prot (P35670.4);
transmembrane region"
misc_feature 2259..2318
/gene="ATP7B"
/gene_synonym="PWD; WC1; WD; WND"
/note="propagated from UniProtKB/Swiss-Prot (P35670.4);
transmembrane region"
misc_feature 2340..2402
/gene="ATP7B"
/gene_synonym="PWD; WC1; WD; WND"
/note="propagated from UniProtKB/Swiss-Prot (P35670.4);
transmembrane region"
misc_feature 2460..2522
/gene="ATP7B"
/gene_synonym="PWD; WC1; WD; WND"
/note="propagated from UniProtKB/Swiss-Prot (P35670.4);
transmembrane region"
misc_feature 2925..2993
/gene="ATP7B"
/gene_synonym="PWD; WC1; WD; WND"
/note="propagated from UniProtKB/Swiss-Prot (P35670.4);
transmembrane region"
misc_feature 3084..3149
/gene="ATP7B"
/gene_synonym="PWD; WC1; WD; WND"
/note="propagated from UniProtKB/Swiss-Prot (P35670.4);
transmembrane region"
misc_feature order(3114..3116,3120..3122,4158..4160)
/gene="ATP7B"
/gene_synonym="PWD; WC1; WD; WND"
/note="putative Cu binding site [ion binding]; other site"
/db_xref="CDD:319783"
misc_feature order(3246..3254,3456..3458,3609..3617,3705..3707,
3825..3833,3891..3893,3900..3902,3909..3911,3966..3968,
3975..3977)
/gene="ATP7B"
/gene_synonym="PWD; WC1; WD; WND"
/note="putative ATP binding site [chemical binding]; other
site"
/db_xref="CDD:319783"
misc_feature 4134..4187
/gene="ATP7B"
/gene_synonym="PWD; WC1; WD; WND"
/note="propagated from UniProtKB/Swiss-Prot (P35670.4);
transmembrane region"
misc_feature 4221..4280
/gene="ATP7B"
/gene_synonym="PWD; WC1; WD; WND"
/note="propagated from UniProtKB/Swiss-Prot (P35670.4);
transmembrane region"
misc_feature 4359..4361
/gene="ATP7B"
/gene_synonym="PWD; WC1; WD; WND"
/note="Phosphoserine.
/evidence=ECO:0000250|UniProtKB:Q64535; propagated from
UniProtKB/Swiss-Prot (P35670.4); phosphorylation site"
exon 219..1452
/gene="ATP7B"
/gene_synonym="PWD; WC1; WD; WND"
/inference="alignment:Splign:2.1.0"
exon 1453..1710
/gene="ATP7B"
/gene_synonym="PWD; WC1; WD; WND"
/inference="alignment:Splign:2.1.0"
exon 1711..1874
/gene="ATP7B"
/gene_synonym="PWD; WC1; WD; WND"
/inference="alignment:Splign:2.1.0"
exon 1875..2036
/gene="ATP7B"
/gene_synonym="PWD; WC1; WD; WND"
/inference="alignment:Splign:2.1.0"
exon 2037..2113
/gene="ATP7B"
/gene_synonym="PWD; WC1; WD; WND"
/inference="alignment:Splign:2.1.0"
exon 2114..2288
/gene="ATP7B"
/gene_synonym="PWD; WC1; WD; WND"
/inference="alignment:Splign:2.1.0"
exon 2289..2522
/gene="ATP7B"
/gene_synonym="PWD; WC1; WD; WND"
/inference="alignment:Splign:2.1.0"
exon 2523..2614
/gene="ATP7B"
/gene_synonym="PWD; WC1; WD; WND"
/inference="alignment:Splign:2.1.0"
exon 2615..2742
/gene="ATP7B"
/gene_synonym="PWD; WC1; WD; WND"
/inference="alignment:Splign:2.1.0"
exon 2743..2897
/gene="ATP7B"
/gene_synonym="PWD; WC1; WD; WND"
/inference="alignment:Splign:2.1.0"
exon 2898..3032
/gene="ATP7B"
/gene_synonym="PWD; WC1; WD; WND"
/inference="alignment:Splign:2.1.0"
exon 3033..3227
/gene="ATP7B"
/gene_synonym="PWD; WC1; WD; WND"
/inference="alignment:Splign:2.1.0"
exon 3228..3410
/gene="ATP7B"
/gene_synonym="PWD; WC1; WD; WND"
/inference="alignment:Splign:2.1.0"
exon 3411..3579
/gene="ATP7B"
/gene_synonym="PWD; WC1; WD; WND"
/inference="alignment:Splign:2.1.0"
exon 3580..3723
/gene="ATP7B"
/gene_synonym="PWD; WC1; WD; WND"
/inference="alignment:Splign:2.1.0"
exon 3724..3866
/gene="ATP7B"
/gene_synonym="PWD; WC1; WD; WND"
/inference="alignment:Splign:2.1.0"
exon 3867..4070
/gene="ATP7B"
/gene_synonym="PWD; WC1; WD; WND"
/inference="alignment:Splign:2.1.0"
exon 4071..4188
/gene="ATP7B"
/gene_synonym="PWD; WC1; WD; WND"
/inference="alignment:Splign:2.1.0"
exon 4189..4291
/gene="ATP7B"
/gene_synonym="PWD; WC1; WD; WND"
/inference="alignment:Splign:2.1.0"
exon 4292..6652
/gene="ATP7B"
/gene_synonym="PWD; WC1; WD; WND"
/inference="alignment:Splign:2.1.0"
regulatory 6625..6630
/regulatory_class="polyA_signal_sequence"
/gene="ATP7B"
/gene_synonym="PWD; WC1; WD; WND"
/note="hexamer: AATAAA"
polyA_site 6652
/gene="ATP7B"
/gene_synonym="PWD; WC1; WD; WND"
/note="major polyA site"
ORIGIN
ctcccccactagaagcccccgcctgggcgcctgcgcccccgttcccggcccaaagcccgccgcccgttggaggccattggctggcctttgcgcacagcggatcgattttccaggtgaccttttgctctgagccagatcagagaagaattcggtgtccgtgcgggacgatgcctgagcaggagagacagatcacagccagagaaggggccagtcggaaaatcttatctaagctttctttgcctacccgtgcctgggaaccagcaatgaagaagagttttgcttttgacaatgttggctatgaaggtggtctggatggcctgggcccttcttctcaggtggccaccagcacagtcaggatcttgggcatgacttgccagtcatgtgtgaagtccattgaggacaggatttccaatttgaaaggcatcatcagcatgaaggtttccctggaacaaggcagtgccactgtgaaatatgtgccatcggttgtgtgcctgcaacaggtttgccatcaaattggggacatgggcttcgaggccagcattgcagaaggaaaggcagcctcctggccctcaaggtccttgcctgcccaggaggctgtggtcaagctccgggtggagggcatgacctgccagtcctgtgtcagctccattgaaggcaaggtccggaaactgcaaggagtagtgagagtcaaagtctcactcagcaaccaagaggccgtcatcacttatcagccttatctcattcagcccgaagacctcagggaccatgtaaatgacatgggatttgaagctgccatcaagagcaaagtggctcccttaagcctgggaccaattgatattgagcggttacaaagcactaacccaaagagacctttatcttctgctaaccagaattttaataattctgagaccttggggcaccaaggaagccatgtggtcaccctccaactgagaatagatggaatgcattgtaagtcttgcgtcttgaatattgaagaaaatattggccagctcctaggggttcaaagtattcaagtgtccttggagaacaaaactgcccaagtaaagtatgacccttcttgtaccagcccagtggctctgcagagggctatcgaggcacttccacctgggaattttaaagtttctcttcctgatggagccgaagggagtgggacagatcacaggtcttccagttctcattcccctggctccccaccgagaaaccaggtccagggcacatgcagtaccactctgattgccattgccggcatgacctgtgcatcctgtgtccattccattgaaggcatgatctcccaactggaaggggtgcagcaaatatcggtgtctttggccgaagggactgcaacagttctttataatccctctgtaattagcccagaagaactcagagctgctatagaagacatgggatttgaggcttcagtcgtttctgaaagctgttctactaaccctcttggaaaccacagtgctgggaattccatggtgcaaactacagatggtacacctacatctgtgcaggaagtggctccccacactgggaggctccctgcaaaccatgccccggacatcttggcaaagtccccacaatcaaccagagcagtggcaccgcagaagtgcttcttacagatcaaaggcatgacctgtgcatcctgtgtgtctaacatagaaaggaatctgcagaaagaagctggtgttctctccgtgttggttgccttgatggcaggaaaggcagagatcaagtatgacccagaggtcatccagcccctcgagatagctcagttcatccaggacctgggttttgaggcagcagtcatggaggactacgcaggctccgatggcaacattgagctgacaatcacagggatgacctgcgcgtcctgtgtccacaacatagagtccaaactcacgaggacaaatggcatcacttatgcctccgttgcccttgccaccagcaaagcccttgttaagtttgacccggaaattatcggtccacgggatattatcaaaattattgaggaaattggctttcatgcttccctggcccagagaaaccccaacgctcatcacttggaccacaagatggaaataaagcagtggaagaagtctttcctgtgcagcctggtgtttggcatccctgtcatggccttaatgatctatatgctgatacccagcaacgagccccaccagtccatggtcctggaccacaacatcattccaggactgtccattctaaatctcatcttctttatcttgtgtacctttgtccagctcctcggtgggtggtacttctacgttcaggcctacaaatctctgagacacaggtcagccaacatggacgtgctcatcgtcctggccacaagcattgcttatgtttattctctggtcatcctggtggttgctgtggctgagaaggcggagaggagccctgtgacattcttcgacacgccccccatgctctttgtgttcattgccctgggccggtggctggaacacttggcaaagagcaaaacctcagaagccctggctaaactcatgtctctccaagccacagaagccaccgttgtgacccttggtgaggacaatttaatcatcagggaggagcaagtccccatggagctggtgcagcggggcgatatcgtcaaggtggtccctgggggaaagtttccagtggatgggaaagtcctggaaggcaataccatggctgatgagtccctcatcacaggagaagccatgccagtcactaagaaacccggaagcactgtaattgcggggtctataaatgcacatggctctgtgctcattaaagctacccacgtgggcaatgacaccactttggctcagattgtgaaactggtggaagaggctcagatgtcaaaggcacccattcagcagctggctgaccggtttagtggatattttgtcccatttatcatcatcatgtcaactttgacgttggtggtatggattgtaatcggttttatcgattttggtgttgttcagagatactttcctaaccccaacaagcacatctcccagacagaggtgatcatccggtttgctttccagacgtccatcacggtgctgtgcattgcctgcccctgctccctggggctggccacgcccacggctgtcatggtgggcaccggggtggccgcgcagaacggcatcctcatcaagggaggcaagcccctggagatggcgcacaagataaagactgtgatgtttgacaagactggcaccattacccatggcgtccccagggtcatgcgggtgctcctgctgggggatgtggccacactgcccctcaggaaggttctggctgtggtggggactgcggaggccagcagtgaacaccccttgggcgtggcagtcaccaaatactgtaaagaggaacttggaacagagaccttgggatactgcacggacttccaggcagtgccaggctgtggaattgggtgcaaagtcagcaacgtggaaggcatcctggcccacagtgagcgccctttgagtgcaccggccagtcacctgaatgaggctggcagccttcccgcagaaaaagatgcagtcccccagaccttctctgtgctgattggaaaccgtgagtggctgaggcgcaacggtttaaccatttctagcgatgtcagtgacgctatgacagaccacgagatgaaaggacagacagccatcctggtggctattgacggtgtgctctgtgggatgatcgcaatcgcagacgctgtcaagcaggaggctgccctggctgtgcacacgctgcagagcatgggtgtggacgtggttctgatcacgggggacaaccggaagacagccagagctattgccacccaggttggcatcaacaaagtctttgcagaggtgctgccttcgcacaaggtggccaaggtccaggagctccagaataaagggaagaaagtcgccatggtgggggatggggtcaatgactccccggccttggcccaggcagacatgggtgtggccattggcaccggcacggatgtggccatcgaggcagccgacgtcgtccttatcagaaatgatttgctggatgtggtggctagcattcacctttccaagaggactgtccgaaggatacgcatcaacctggtcctggcactgatttataacctggttgggatacccattgcagcaggtgtcttcatgcccatcggcattgtgctgcagccctggatgggctcagcggccatggcagcctcctctgtgtctgtggtgctctcatccctgcagctcaagtgctataagaagcctgacctggagaggtatgaggcacaggcgcatggccacatgaagcccctgacggcatcccaggtcagtgtgcacataggcatggatgacaggtggcgggactcccccagggccacaccatgggaccaggtcagctatgtcagccaggtgtcgctgtcctccctgacgtccgacaagccatctcggcacagcgctgcagcagacgatgatggggacaagtggtctctgctcctgaatggcagggatgaggagcagtacatctgatgacttcaggcaggcgggccggggcagggacttgcctccactcaccacaagctgagcaggacagccagcagcaggatgggctgagctagcctccagctttggggacttccgctccctggatatgtccagtcatcctgccctgcagcacgcggccttgtctgggtgcagctgggcttggcctggagaggacggccctgcctgcctcttggcctcacgggaccgtcagcatgggctttgtcttggactctagtccttggctggactgtagaaggtgagaggcgagtcaccctcctcacagacctctgcttggagtatttaggatgactgctgtgaaatggagaacagtttcatcaggaccaaaaaacctcactgggcctttccagagaactgcagacctcactgtcagggtctttctgatgacgcctgtctgtgtgcatcatgtttctgagaccacagtttacctcaggtgtgcctgttgctttcttcctgcatagtctgttcctttcttcgtacatagtctgttccttttctctcctgtgtgcttgtcagtggggacccctcgcaaccctgcctgtcacctgggagggtgggaccaatgtccttgtggtctttgctgctgctctcaggcgcttctccaatgctctggagtgtgcatttcagcttgaacctgcttcctggctcacacatccccagccagggagcttgccacactcttcttcaagttgaggagagttcttttttgcttaaagcccccttctccatggagtgttggcttctcaatagagtgttgttgctgaccagctggagtgagggcctcagagcctgacctgagagtccgtactcggcttcctgtggggtgtaggttctcgcgattcaggacgtccttccatatccctgcccagcctgtggtgcttgaaacgtttgccccatgggaaacgtatgtgtgcaggagcctccctgcacggcccaaggggcttcgttttcagtcttctgactgtcacctcgtggggttcagtagagaattcatgtgactagcgcctggccttgtgtggcttggaggaaatggtactgcccaaataggaggaaaacacagcctccctgagcctgcattctgcacgctgcccaggggcttcagaaaaggagtggccacagcaccccgaagggagcatctgtttacctggcagtggctctcagagcagcagaacgggttcagttttagactctgaagttggttgtgattgacagaaccctttgggagcaaactagtagagttggattaaattctgggtgaaacccttttctcccacacaaaatagttttagtgatttttttcattgtccattacttgccaggggcagttttagcagcacttttgatagattacgtctaatcctcccaaccaaccagcagggtagctattactgtccacattttacaggcaaggaaacaggctccaagaggctgaggactttgcccaggatgacatagccaatggacaagcagtgtctgtcagctgtgaaggcttcactcttattgtccttctaccttgaatagaagttttcctgataagaataaacgaggaaaaggtccttgcctcctggaagaacaaatctaccaggtgatctattcattgtttcaactcagaatgcacttgattcaggaggtcatctgaccttcaccttggatggttagtttcactttttacatatagtttttgcagggttttattttataaaatccaagcgcgctgttgattgtgttttccttgttttcagcccccccactccagcccgcagcacatttccgctgtccgtcagtaattgtgtcctctctttatgcttgcttggggaatgttgttttctgactaggctgatcattatctaaagaatctaattctgttgatttttaaaacttttaggaccataaacgttgtgttcatatatggacatggaaatatttatataattttatagaaaataaccttttagatggtcaaagtgtaaggagtttttttgtcagataatcatttctacttcaaaaacatttcatgcaatattagaataaagttcctgtcattcctctaaaaa
//
by
@meso_cacase at
DBCLS
This page is licensed under a
Creative Commons Attribution 4.0 International License (CC BY 4.0).
If you use GGRNA in your work, please cite:
Naito Y, Bono H. (2012)
GGRNA: an ultrafast, transcript-oriented search engine for genes and transcripts.
Nucleic Acids Res., 40, W592-W596.
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