LOCUS       NM_001164471            1179 bp    mRNA    linear   PRI 31-DEC-2022
DEFINITION  Homo sapiens testis specific protein Y-linked 4 (TSPY4), mRNA.
ACCESSION   NM_001164471 XM_001126990
VERSION     NM_001164471.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1179)
  AUTHORS   Gaudet P, Livstone MS, Lewis SE and Thomas PD.
  TITLE     Phylogenetic-based propagation of functional annotations within the
            Gene Ontology consortium
  JOURNAL   Brief Bioinform 12 (5), 449-462 (2011)
   PUBMED   21873635
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC006158.6.
            
            On Jul 14, 2021 this sequence version replaced NM_001164471.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA1968968,
                              SAMEA2148093 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000426950.6/ ENSP00000399668.2
            RefSeq Select criteria :: based on manual assertion, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-550               AC006158.6         44110-44659
            551-628             AC006158.6         45267-45344
            629-740             AC006158.6         45473-45584
            741-886             AC006158.6         45686-45831
            887-968             AC006158.6         45938-46019
            969-1179            AC006158.6         46714-46924
FEATURES             Location/Qualifiers
     source          1..1179
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="Y"
                     /map="Yp11.2"
     gene            1..1179
                     /gene="TSPY4"
                     /gene_synonym="TSPY10; TSPY8"
                     /note="testis specific protein Y-linked 4"
                     /db_xref="GeneID:728395"
                     /db_xref="HGNC:HGNC:37287"
     exon            1..550
                     /gene="TSPY4"
                     /gene_synonym="TSPY10; TSPY8"
                     /inference="alignment:Splign:2.1.0"
     variation       25
                     /gene="TSPY4"
                     /gene_synonym="TSPY10; TSPY8"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1603139224"
     CDS             47..991
                     /gene="TSPY4"
                     /gene_synonym="TSPY10; TSPY8"
                     /codon_start=1
                     /product="testis-specific Y-encoded protein 4"
                     /protein_id="NP_001157943.1"
                     /db_xref="CCDS:CCDS48202.1"
                     /db_xref="GeneID:728395"
                     /db_xref="HGNC:HGNC:37287"
                     /translation="

MRPEGSLTYRVPERLRQGFCGVGRAAQALVCASAKEGTAFRMEAVQEGAAGVESEQAALGEEAVLLLDDIMAEVEVVAEVEVVAEEEGLVERREEAQRAQQAVPGPGPMTPESALEELLAVQVELEPVNAQARKAFSRQREKMERRRKPHLDRRGAVIQSVPGFWANVIANHPQMSALITDEDEDMLSYMVSLEVEEEKHPVHLCKIMLFFRSNPYFQNKVITKEYLVNITEYRASHSTPIEWYPDYEVEAYRRRHHNSSLNFFNWFSDHNFAGSNKIAEILCKDLWRNPLQYYKRMKPPEEGTETSGDSQLLS"

     misc_feature    440..928
                     /gene="TSPY4"
                     /gene_synonym="TSPY10; TSPY8"
                     /note="Nucleosome assembly protein (NAP); Region: NAP;
                     cl08298"
                     /db_xref="CDD:447601"
     variation       73
                     /gene="TSPY4"
                     /gene_synonym="TSPY10; TSPY8"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2124348711"
     variation       74
                     /gene="TSPY4"
                     /gene_synonym="TSPY10; TSPY8"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:879057884"
     variation       76
                     /gene="TSPY4"
                     /gene_synonym="TSPY10; TSPY8"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1603139241"
     variation       181
                     /gene="TSPY4"
                     /gene_synonym="TSPY10; TSPY8"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1199155386"
     variation       187
                     /gene="TSPY4"
                     /gene_synonym="TSPY10; TSPY8"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1603139246"
     variation       196
                     /gene="TSPY4"
                     /gene_synonym="TSPY10; TSPY8"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1603139251"
     variation       201
                     /gene="TSPY4"
                     /gene_synonym="TSPY10; TSPY8"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1603139257"
     variation       258..302
                     /gene="TSPY4"
                     /gene_synonym="TSPY10; TSPY8"
                     /replace="tggcggaggtggaggtggtggcggagg"
                     /replace="tggcggaggtggaggtggtggcggaggtggaggtggtggcggagg"
                     /db_xref="dbSNP:1569405389"
     variation       267
                     /gene="TSPY4"
                     /gene_synonym="TSPY10; TSPY8"
                     /replace="a"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1603139262"
     variation       285
                     /gene="TSPY4"
                     /gene_synonym="TSPY10; TSPY8"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1603139267"
     variation       291
                     /gene="TSPY4"
                     /gene_synonym="TSPY10; TSPY8"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1603139270"
     variation       327
                     /gene="TSPY4"
                     /gene_synonym="TSPY10; TSPY8"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1603139271"
     variation       330
                     /gene="TSPY4"
                     /gene_synonym="TSPY10; TSPY8"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1603139275"
     variation       383
                     /gene="TSPY4"
                     /gene_synonym="TSPY10; TSPY8"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1603139282"
     variation       455
                     /gene="TSPY4"
                     /gene_synonym="TSPY10; TSPY8"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:1556179159"
     variation       464
                     /gene="TSPY4"
                     /gene_synonym="TSPY10; TSPY8"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1259762569"
     variation       478
                     /gene="TSPY4"
                     /gene_synonym="TSPY10; TSPY8"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1459765083"
     variation       496
                     /gene="TSPY4"
                     /gene_synonym="TSPY10; TSPY8"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1332765786"
     variation       503
                     /gene="TSPY4"
                     /gene_synonym="TSPY10; TSPY8"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1199647885"
     variation       522
                     /gene="TSPY4"
                     /gene_synonym="TSPY10; TSPY8"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1257206373"
     exon            551..628
                     /gene="TSPY4"
                     /gene_synonym="TSPY10; TSPY8"
                     /inference="alignment:Splign:2.1.0"
     exon            629..740
                     /gene="TSPY4"
                     /gene_synonym="TSPY10; TSPY8"
                     /inference="alignment:Splign:2.1.0"
     exon            741..886
                     /gene="TSPY4"
                     /gene_synonym="TSPY10; TSPY8"
                     /inference="alignment:Splign:2.1.0"
     variation       775
                     /gene="TSPY4"
                     /gene_synonym="TSPY10; TSPY8"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1556179224"
     variation       803
                     /gene="TSPY4"
                     /gene_synonym="TSPY10; TSPY8"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1556179230"
     exon            887..968
                     /gene="TSPY4"
                     /gene_synonym="TSPY10; TSPY8"
                     /inference="alignment:Splign:2.1.0"
     variation       964
                     /gene="TSPY4"
                     /gene_synonym="TSPY10; TSPY8"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1556179243"
     exon            969..1179
                     /gene="TSPY4"
                     /gene_synonym="TSPY10; TSPY8"
                     /inference="alignment:Splign:2.1.0"
     variation       975
                     /gene="TSPY4"
                     /gene_synonym="TSPY10; TSPY8"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1556179264"
     variation       977
                     /gene="TSPY4"
                     /gene_synonym="TSPY10; TSPY8"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1603139360"
     variation       1034
                     /gene="TSPY4"
                     /gene_synonym="TSPY10; TSPY8"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:3876329"
     variation       1037
                     /gene="TSPY4"
                     /gene_synonym="TSPY10; TSPY8"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1556179279"
ORIGIN      

ggcccttcgcgcgcagtcccttagggggcgcctggaagcccggcgcatgcgccctgagggctcgctgacctaccgggtgccagagaggctgcggcagggtttctgtggcgtgggtcgggcagcacaggccttggtgtgtgcgagtgccaaggagggcaccgccttcaggatggaggctgtacaggagggggcggccggggtggagagtgagcaggcggctttgggggaggaggcggtgctgctgttggatgacataatggcggaggtggaggtggtggcggaggtggaggtggtggcggaggaggagggcctcgtggagcggcgggaggaggcccagcgggcacagcaggctgtgcctggccctgggcccatgaccccagagtctgcactggaggagctgctggccgttcaggtggagctggagccggttaatgcccaagccaggaaggccttttctcggcagcgggaaaagatggagcggaggcgcaagccccacctagaccgcagaggcgccgtcatccagagcgtccctggcttctgggccaatgttattgcaaaccacccccagatgtcagccctgatcactgacgaagatgaagacatgctgagctacatggtcagcctggaggtggaagaagagaagcatcctgttcatctctgcaagatcatgttgttctttcggagtaacccctacttccagaataaagtgattaccaaggaatatctggtgaacatcacagaatacagggcttctcattccactccaattgagtggtatccggattatgaagtggaggcctatcgccgcagacaccacaacagcagccttaacttcttcaactggttctctgaccacaacttcgcaggatctaacaagattgctgagatcctatgtaaggacctgtggcgcaatcccctgcaatactacaagaggatgaagccacctgaagagggaacagagacgtcaggggactcccagttgttgagttgaatatgatggagcatcagattttacctaatacagcagaactcctaaaaagttacagccatatgcaggacggcagtactcagcatggtcttatgcacaggaactaaaggaaaaagagatcgagtcacaaaaattcaggaagagggggtaaatgtggattgtatggaatgaaaaataaacattctcaagga

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