LOCUS       NM_001031539            6405 bp    mRNA    linear   VRT 24-SEP-2023
DEFINITION  Gallus gallus ELOVL fatty acid elongase 6 (ELOVL6), mRNA.
ACCESSION   NM_001031539 XM_426328
VERSION     NM_001031539.2
KEYWORDS    RefSeq.
SOURCE      Gallus gallus (chicken)
  ORGANISM  Gallus gallus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
            Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes;
            Phasianidae; Phasianinae; Gallus.
REFERENCE   1  (bases 1 to 6405)
  AUTHORS   Zhang DD, Wang DD, Wang Z, Wang YB, Li GX, Sun GR, Tian YD, Han RL,
            Li ZJ, Jiang RR, Liu XJ, Kang XT and Li H.
  TITLE     Estrogen Abolishes the Repression Role of gga-miR-221-5p Targeting
            ELOVL6 and SQLE to Promote Lipid Synthesis in Chicken Liver
  JOURNAL   Int J Mol Sci 21 (5), 1624 (2020)
   PUBMED   32120850
  REMARK    GeneRIF: Estrogen Abolishes the Repression Role of gga-miR-221-5p
            Targeting ELOVL6 and SQLE to Promote Lipid Synthesis in Chicken
            Liver.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6405)
  AUTHORS   Tang H, Finn RD and Thomas PD.
  TITLE     TreeGrafter: phylogenetic tree-based annotation of proteins with
            Gene Ontology terms and other annotations
  JOURNAL   Bioinformatics 35 (3), 518-520 (2019)
   PUBMED   30032202
REFERENCE   3  (bases 1 to 6405)
  AUTHORS   Burge S, Kelly E, Lonsdale D, Mutowo-Muellenet P, McAnulla C,
            Mitchell A, Sangrador-Vegas A, Yong SY, Mulder N and Hunter S.
  TITLE     Manual GO annotation of predictive protein signatures: the InterPro
            approach to GO curation
  JOURNAL   Database (Oxford) 2012, bar068 (2012)
   PUBMED   22301074
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 6405)
  AUTHORS   Caldwell RB, Kierzek AM, Arakawa H, Bezzubov Y, Zaim J, Fiedler P,
            Kutter S, Blagodatski A, Kostovska D, Koter M, Plachy J, Carninci
            P, Hayashizaki Y and Buerstedde JM.
  TITLE     Full-length cDNAs from chicken bursal lymphocytes to facilitate
            gene function analysis
  JOURNAL   Genome Biol 6 (1), R6 (2005)
   PUBMED   15642098
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAENSK010000074.1.
            
            On Nov 5, 2021 this sequence version replaced NM_001031539.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AJ720366.1, SRR13267649.176987.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA103992290, SAMEA103992323
                                           [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-237               JAENSK010000074.1  10474663-10474899
            238-369             JAENSK010000074.1  10518516-10518647
            370-521             JAENSK010000074.1  10535715-10535866
            522-6405            JAENSK010000074.1  10538630-10544513
FEATURES             Location/Qualifiers
     source          1..6405
                     /organism="Gallus gallus"
                     /mol_type="mRNA"
                     /db_xref="taxon:9031"
                     /chromosome="4"
                     /map="4"
     gene            1..6405
                     /gene="ELOVL6"
                     /note="ELOVL fatty acid elongase 6"
                     /db_xref="CGNC:53457"
                     /db_xref="GeneID:428772"
     exon            1..237
                     /gene="ELOVL6"
                     /inference="alignment:Splign:2.1.0"
     misc_feature    35..37
                     /gene="ELOVL6"
                     /note="upstream in-frame stop codon"
     CDS             149..946
                     /gene="ELOVL6"
                     /EC_number="2.3.1.199"
                     /note="elongation of very long chain fatty acids family
                     member protein 6; 3-keto acyl-CoA synthase ELOVL6; ELOVL
                     family member 6, elongation of long chain fatty acids
                     (FEN1/Elo2, SUR4/Elo3-like, yeast); ELOVL FA elongase 6;
                     very long chain 3-oxoacyl-CoA synthase 6; very long chain
                     3-ketoacyl-CoA synthase 6"
                     /codon_start=1
                     /product="elongation of very long chain fatty acids
                     protein 6"
                     /protein_id="NP_001026710.1"
                     /db_xref="CGNC:53457"
                     /db_xref="GeneID:428772"
                     /translation="

MNMSVLTLQEYEFEKQFNEHEAIQWMQENWKKSFLFSALYAAFIFGGRHLMNKRAKFELRKPLVLWSLSLAVFSIFGAVRTAPYMLYILMTKGLKQSVCDQSFYIGPVSKFWAYAFVLSKAPELGDTIFIILRKQKLIFLHWYHHITVLLYSWYSYKDMVAGGGWFMTMNYGVHAVMYSYYALRAAGFRVSRKFAMFITLSQITQMLVGCVINYLVFSWMQHGQCHSHVQNIIWSSLMYLSYFVLFCHFFFEAYIGKTTKARKVD"

     misc_feature    152..154
                     /gene="ELOVL6"
                     /note="N-linked (GlcNAc...) asparagine.
                     /evidence=ECO:0000255|HAMAP-Rule:MF_03206; propagated from
                     UniProtKB/Swiss-Prot (Q5ZJR8.1); glycosylation site"
     misc_feature    224..931
                     /gene="ELOVL6"
                     /note="GNS1/SUR4 family; Region: ELO; pfam01151"
                     /db_xref="CDD:426083"
     misc_feature    248..301
                     /gene="ELOVL6"
                     /note="propagated from UniProtKB/Swiss-Prot (Q5ZJR8.1);
                     transmembrane region"
     misc_feature    356..418
                     /gene="ELOVL6"
                     /note="propagated from UniProtKB/Swiss-Prot (Q5ZJR8.1);
                     transmembrane region"
     misc_feature    479..541
                     /gene="ELOVL6"
                     /note="propagated from UniProtKB/Swiss-Prot (Q5ZJR8.1);
                     transmembrane region"
     misc_feature    557..616
                     /gene="ELOVL6"
                     /note="propagated from UniProtKB/Swiss-Prot (Q5ZJR8.1);
                     transmembrane region"
     misc_feature    623..685
                     /gene="ELOVL6"
                     /note="propagated from UniProtKB/Swiss-Prot (Q5ZJR8.1);
                     transmembrane region"
     misc_feature    737..799
                     /gene="ELOVL6"
                     /note="propagated from UniProtKB/Swiss-Prot (Q5ZJR8.1);
                     transmembrane region"
     misc_feature    842..904
                     /gene="ELOVL6"
                     /note="propagated from UniProtKB/Swiss-Prot (Q5ZJR8.1);
                     transmembrane region"
     exon            238..369
                     /gene="ELOVL6"
                     /inference="alignment:Splign:2.1.0"
     exon            370..521
                     /gene="ELOVL6"
                     /inference="alignment:Splign:2.1.0"
     exon            522..6405
                     /gene="ELOVL6"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      

gggaggagaggcgcggaggggagcggagctatgctaaacctggggtaccgctgaggcggggcagccaggccggaggcgggagctctccggctcccgaggcggcaggcggcatttcggcgcggggagcggctccgcagccaccgggccaatgaacatgtccgtgttgactttgcaggaatacgaattcgagaagcagttcaacgagcatgaggccatccagtggatgcaggagaactggaagaaatcttttctattttcagcactgtacgctgccttcatatttggtggtcggcacctaatgaataaacgagcaaaatttgaactgaggaaaccactagtgctctggtccctgagccttgctgtcttcagtatattcggtgctgttcgaactgctccttacatgctgtacattttgatgaccaaaggcctgaagcagtcagtgtgtgaccagagtttttacattggacctgtcagcaaattctgggcatatgcatttgtgctaagcaaagcacctgaactaggagatacaatattcattattcttaggaaacagaagctcatcttcttacactggtaccaccacattactgtgttactttattcttggtattcctacaaggacatggtggctggcggtggctggtttatgaccatgaactatggagtgcacgccgttatgtactcttactatgccttgcgggctgctggcttcagagtctcacgcaagtttgccatgttcatcaccttgtcgcagatcacccagatgttggtcggctgtgtaatcaactatctggtcttctcctggatgcagcatggccagtgccattcccacgtgcagaatatcatctggtcctctctcatgtacctcagctactttgtgctcttctgccattttttctttgaggcctatatcggcaaaaccacaaaagcaaggaaggttgactagtggtaagaatgagacagaagccatagctcagggtcatcaagaaaaacaaaactacaagaaaagaaaatggcacaaggaaacacatatatgtatggtgcagctaaaacttggcagcttagggaaagttagcttggtttaacccagtaagtttatgatcctatcatggtgaggactcactgaaatctactctaactcaaaggactgctgacaaaagactccttccttcttgtacctgcctgctccagaaaagaaaggagaaaaggagaaacagaaaaaaagtgagaagaaaagagaagaaaagcagaaaggaataatattgagaggaaaaaatatagtacattaaataaactgtgtttccctgggatggaaaaaaaatttattgtgaaaaaaagtttctaaattctttctaatagtttttcagcattaaagttgaacaagacattgacattaatggtaggattgtgaaattaaaatcttttctgtaaaaggtttataccttcagccagaatgaaatccaagaggatgtcacgtacacctatgcggaaagcggttgaactccattgtggtcatgaatggcagcaagaagagattgagtgctctgttctgtcctgtgccaagggagtagagctgggaggcaggcacctctctggagtgcaggaaggagcaggacttgtacaagagcctaacatgaaaacaagtgctgttgcaatacatatctcagcaagtgcattttccaagtgcgcttttcagctaaaggcaaggagtttctgcagcaggataagacatagagggttaaatcaactgatatttgctaaattaccaggggctaatagcagatgaatgttcaggaaggagagggaggcaactactgaaacgtgatttttaagaattatccattaatctcaaattaacccacagcaacacggaatggaatgaggggaaatgagaagccactcttgccagcgagcggcccctcttcccattgattcccaagccgtgcgtcaggtggacctgggaggcaaggcaaggggaagaggcgcaggaccaggcagcgctgggtggctctgtgcctctgcacgcacctgccaggctgggcgaagatgtgccaagagccctcccctggtcacatggagatactactgcaaaacatgcccggaataagattttcttggcatcggtataggaaatcagtctgagcggagtgattttgctgcaatggcttagctctaatgtccagagagaattgttcttcattaaacgtgtatctctctctctgcagagtctgtactgtaacatcagactgaccactaaagaagacgctcttcttctccacagtcggctacagaaataaggagaaacgtatttcactctgaaccttagagagctagttgataacagccatattctctcaaagacggatagattgcattatctgtgatattccagtccttacaaagccaaataaaatgtgtaaaagttcctagtatttcaaagacgcaagtatgtaaacttgatgttaaatgtgttaatgtagtactctaaattgtatcagttaggtagcttaactaaacaattagaagaactagatcaacaaaataggggctgctgttctgcgtagaatacacacacctataactacacccatatacacgttctgtgaattgtcagcaagaaaaaagcccagcggcagagaatcacatttcctggctaacgcaaaagattgtcattatctttcttgttttaatttgagattgtacagtgcaaagggtttggttttttttttaattacgatttttagctttaattgtgctgtcattcatgaaacagagctgctttagtatcctgttaagagatgacaagggcttttggtgtctcattatatacaaaagaaaaacaaataaagttacattccatgttatgtgaatggtcttacaaatcaaaaagcctccgtaggccgaaatcataattataacaagcagaaaagatgtttacatttgtgttatttaagttattgatgtgctgacgttattttatggtacacaacaaacagcaaaatgtgatatccagtaatgaagctatgatattcattaataggactactgtatacatggaaacaataggcaaaaccaattaaatgtgtaaaccatcttgttttacagcttgggagtagataactgtaatgctgagtaagcctttatcctcacgcttaattttgccctggctaagaaccaggttatgaagactgagtaacagggaaaacccaaatttcaagttccctaccccgcagatgggaagtgttggtagaagccccatcgtgccacgcaaggagctgcacgcaacccctggtagctggaagattgcaggtaaaggctaaaaagcccaagaagctttacaagtaggaagtgatactgcagctaggtgaagacctgtggcccaagttttacacagacagaaaacagagcgggttgctaacaagtgtgcaaacaacccactgtgttttgtacactgtgttccttaattgcatgaggggaaaaaaaaaaaaaagaaagaaaaaaaagcattgtgtgtgtgccagatggagatgctggcaatgccaacactgagttgagcagagcaggcattttacccgttccctgaaagtcctcacaggtgctgtttgctcccaacctgcctgcatccctgtgagcactcacgttagacctggaggtgtccccacacatcccaaggatcaggttcctcctctgctgcctggtcagtagctccagagcaagggctgacctacaggcctcctccagatgcagtataggtgtgccccacgtgtgcagggaaaagtgggggcgtccagtgggaggataggtttgcgggcgagtatgtgtatagggaagggacagcaagatcagacacgtaaggaacaaatgaggatacctctgccatcagaagttggaactgccatgtcacagaggcatttctacaggtcctatggccatagggcttctcctctgagatttttcactggaggcaagtgtggcaactaacattaaagaagttgaggataagaccaaagtcaacatacgctgtttttcttttttggttgttttgttttgtttttccctttaaaaagtgcatacttgatagttagacatcacttttaacccatacacctaaacagcaaggcagtcatccctaagctaatgacacctctaatattctagctgttccaacccaaacacagctaattgggtcctacttatttcccctgatttaagccttggggccacacttgcacactattctgtcactaccagaaccctttttttttggcaataacttttaagtaaagttgcagttctgccatattcacacataccttgggggactccagcttgcagagtgcgccaaacattatgggactgtgacagtgaccacaatgctgtcaggggattcactgctgaagtcaggcaagttacactgatgataaggtcagtctgccagggccgaggtctgtgcttgatgtctgacacatttatccagtgtactgaaataaaaacagtagggttgtgcaggtttacctgtaagcaaccgtgagcaggatttggtaggaaaacatcaagaagccggctaagagcaaagttccttcaagctatgcctgtgaggagaaggaaagccctcatgctgacaagccttctgtaagtcagtcacagatgatgtgcatctcagctcactggtaacatgtaagtggctgcttcccaaagacatctttcagcacaatttcaaaggaaactaataaaagcattatcttaccataagggtttaagcatgcgaaaggaatcagtcaaagaggtccagctgaacagcagggataaataaagcctgttttgtaggggagcacaaactgcaggcgaggtggcagcggagaccagtcggtgccttggtagggaggaagcttcgaggacagggctgaaccactgctggactgactcgtgcccagtggcctgcttgccatgagggtgggccgtgatggaaggaggctgcagccaaagacctgcggtctgctggtctgtgctttaacagccggcccactgctgggcacgtcgtttctttatcctagaaagaaaaacgtaggagaatggattaactgagagcaacgacacctaggggatcaatatcaggttttcaggtaacagccagtgaaaggcgccaattaccgtggccatgacacagcagcctttgtaagcatgtgccataacgtctccagtatttgcattctgtctctgtacttcagaaccagaaaaagagctattgatacacaagccgtaaatgcagaaccacttttaagtaacaaaagtggcactggttgaggaagaaagctcagcagagtgcggtttgtgccacataagctcagcacacggctgaatacctgcagaaaatgagattgctagtcaggtgcctggagatgtgcaccagctttgcttcagtcgattgcagtgtggttggttcagagggcagtgacacaaactgccaaggccctggcgttagtcctcagtcctatttcccagccccacctcaatgagccttctaaaagagaagaaatacagctcagcactctcagcgtgtttctactcttttatttcaatacattttcatggaatcccacagaatggcaggggttggaagggacctctagcgaccgttgagtccaacccccctgataaagcaggtaaaatatagcagaggatggttgcccatcccatttattttattaaaaaacaagctacaagatgagtccctgatcctgctattacaaatgctccattgtggtcagtgtacacgggcacagaaaccctttgcttacaggggcaaggacaggatcagtgccttgttaaagacttactctctagcagagcaacaaccacacacagactagaattaatttgatttcttaaacacatataaggtgagatctgcacaagagccctacaccgaagggagaccagggacctcccagtgcaccataaagctcaataaaatgctgcatggagtggggtcagagggtatttcccaatgggtatgaaatgatattcccctgaaatagtgaccttcctgagaagtctcacgtctgtccggccctggacagcttcagacagggctgactgctggaaaaacacagctctgattgacttatctgctttctctaaagagccactacatgctttaggctttgaggagccttaaagctcgagctagatttctattcagaaaaaagaaaaaaaaagaaaaaaaaaacaagggaaaataatacatgtacaatagctacgagagaatagtatgagaaatacctttattttaccattttcaaatggctatttcactacataaaaggaagtttttatttttattttttttttcttttggtatattgatattccaaataaaattttaacttttggttcaaaagaaaa

//