2024-05-04 18:40:45, GGRNA.v2 : RefSeq release 222 (Jan, 2024)
LOCUS XM_039103065 2580 bp mRNA linear ROD 11-JUN-2023 DEFINITION PREDICTED: Rattus norvegicus ISL LIM homeobox 1 (Isl1), transcript variant X1, mRNA. ACCESSION XM_039103065 VERSION XM_039103065.1 DBLINK BioProject: PRJNA677964 KEYWORDS RefSeq. SOURCE Rattus norvegicus (Norway rat) ORGANISM Rattus norvegicus Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus. COMMENT MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_051337.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Updated annotation Annotation Name :: GCF_015227675.2-RS_2023_06 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.1 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 06/06/2023 ##Genome-Annotation-Data-END## FEATURES Location/Qualifiers source 1..2580 /organism="Rattus norvegicus" /mol_type="mRNA" /strain="BN/NHsdMcwi" /db_xref="taxon:10116" /chromosome="2" /sex="male" /tissue_type="kidney" /country="USA: Wisconsin, Milwaukee, Medical College of Wisconsin" /collection_date="2019-03-08" /collected_by="Rebecca Schilling" gene 1..2580 /gene="Isl1" /gene_synonym="Isl-1; isl-1=homeobox" /note="ISL LIM homeobox 1; Derived by automated computational analysis using gene prediction method: Gnomon. Supporting evidence includes similarity to: 14 ESTs, 1 Protein, and 100% coverage of the annotated genomic feature by RNAseq alignments, including 27 samples with support for all annotated introns" /db_xref="GeneID:64444" /db_xref="RGD:61957" CDS 266..1306 /gene="Isl1" /gene_synonym="Isl-1; isl-1=homeobox" /codon_start=1 /product="insulin gene enhancer protein ISL-1 isoform X1" /protein_id="XP_038958993.1" /db_xref="GeneID:64444" /db_xref="RGD:61957" /translation="
MGDMGDPPKKKRLISLCVGCGNQIHDQYILRVSPDLEWHAACLKCAECNQYLDESCTCFVRDGKTYCKRDYIRLYGIKCAKCSIGFSKNDFVMRARSKVYHIECFRCVACSRQLIPGDEFALREDGLFCRADHDVVERASLGAGDPLSPLHPARPLQMAAEPISARQPALRPHVHKQPEKTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKRSIMMKQLQQQQPNDKTNIQGMTGTPMVAASPERHDGGLQANPVEVQSYQPPWKVLSDFALQSDIDQPAFQQLAVINYKDFRDHLGIWISHQSIFQKEDQALIPLAVK"
misc_feature 314..478 /gene="Isl1" /gene_synonym="Isl-1; isl-1=homeobox" /note="The first LIM domain of Isl, a member of LHX protein family; Region: LIM1_Isl; cd09366" /db_xref="CDD:188752" misc_feature order(314..316,323..325,380..382,389..391,398..400, 407..409,464..466,473..475) /gene="Isl1" /gene_synonym="Isl-1; isl-1=homeobox" /note="Zn binding site [ion binding]; other site" /db_xref="CDD:188752" misc_feature 500..664 /gene="Isl1" /gene_synonym="Isl-1; isl-1=homeobox" /note="The second LIM domain of Isl, a member of LHX protein family; Region: LIM2_Isl; cd09374" /db_xref="CDD:188760" misc_feature order(500..502,509..511,566..568,575..577,584..586, 593..595,650..652,659..661) /gene="Isl1" /gene_synonym="Isl-1; isl-1=homeobox" /note="Zn binding site [ion binding]; other site" /db_xref="CDD:188760" misc_feature 806..976 /gene="Isl1" /gene_synonym="Isl-1; isl-1=homeobox" /note="Homeodomain; Region: HOX; smart00389" /db_xref="CDD:197696" misc_feature order(812..823,827..829,878..880,896..898,935..937, 941..946,953..958,962..970,974..979) /gene="Isl1" /gene_synonym="Isl-1; isl-1=homeobox" /note="DNA binding site [nucleotide binding]" /db_xref="CDD:238039" misc_feature order(815..817,824..826,944..946,953..958,965..967) /gene="Isl1" /gene_synonym="Isl-1; isl-1=homeobox" /note="specific DNA base contacts [nucleotide binding]; other site" /db_xref="CDD:238039" ORIGIN
agtttgagtaagagataaggaagagaggtgccccgagccgcgcgagtccgccgccgctgcgcctcagctccgccaactccgccggcttaaatcggactcctagatccgcgagggcgcggcgcagccgggcagcgctttcccccagccttggcaaccccaggggccactatttgccacctagccacagcaccagcatcctctctgtgggctgttcaccaattgtccaaccaccatttcactgtggacattactccctcttacagatatgggagacatgggcgatccaccaaaaaaaaaacgtctgatttccctatgtgttggttgcggtaatcaaattcacgatcagtatattctgagggtttctccggatttggaatggcatgcggcatgtttgaaatgtgcggagtgtaatcagtatttggacgaaagctgtacctgctttgttagggacgggaaaacctactgtaaaagagattatatcaggttgtacgggatcaaatgcgccaagtgcagcataggcttcagcaagaacgacttcgtgatgcgcgcccgctctaaggtgtaccacatcgaatgtttccgctgtgtagcatgcagccgacagctcatcccgggagacgaattcgcgctgcgggaggatgggcttttctgccgcgcggaccacgatgtagtggagagggccagcctaggagctggagaccctctcagtcccttgcatccagcgcggcctctgcaaatggcagccgagcccatctccgctaggcagccagctctgcggccgcacgtccacaaacagcccgagaagaccacccgagtgcggactgtgctcaacgaaaagcagctgcacaccttgcggacctgctacgcagccaaccctcggccagatgcgctcatgaaggagcaactagtggagatgaccggcctcagtccccgagtcatccgggtctggtttcaaaacaagaggtgcaaggacaagaaacgcagcatcatgatgaagcagctccagcagcagcaacccaacgacaaaactaatatccaggggatgacaggaactcccatggtggctgctagtccggagagacatgatggtggtttacaggctaacccagttgaggtgcaaagttaccagccgccctggaaagtactgagtgacttcgccttgcaaagtgacatagatcagcctgcttttcagcaactggctgttataaattacaaggacttcagagaccaccttggcatttggatcagccatcagtcaatttttcagaaggaggaccaggctctaattccactggcagtgaagtagcatcgatgtcctctcagctcccagatacacccaacagcatggtagccagtcctatagaggcatgaggaacattcattcagatgttttgttttgttttgtttttcccctgttggagaacgtgggaaatgacgttgaactccggaataaaagtatttaacgacccagtcaatgaaaactgaatcaagaaacgaatgctccatgaaatgcacgaagtctgttttaatgacaaggtgatatggtagcaacactgtgaagacaatcatgggattttactagaattaaaaacaaacaaaaccctaagcccaacatatgctattcaatgaccttaggaggactgaaaaagaaaaaggaaaaaaaaaaagagagagagagagagacgtttttaaaacgtagaggatttatattcaaggatctcaaaactgcgcattttcatttcactgcacatctagaggaaaagcagaaatagagaatttcctagtccatcctattctgaatggtgctgtttctatattggtcattgccttgccaaacaggagctccacatagagcggaagaaaccagcctcagtggctgaaagagtcctttcaggaaggcggggctgcattggctgcattggtttgcgatgtttttagttgaccttgacaaggggttaagtgaaattctgggtctctttagcatgccctgtacctggtttctcttttacctttgcctcttctcccattattttctttcctttatttttctttacatattttttttttgagatccatcctctatcaagaagtctgaagggactttaaaggtttttgaatttatatttaaaaaccaacttataaagcattgcaacaaggttacctctattttgccacaagcgtctcgggattgtgtttgactcgtgtctgtccaagaacttttcccccaaagatgtgtatagttattggttaaaatgactgttttcgctctttctggaaataaagaggaaaaaaggaaactttttttttgtttgctcttgcattgcaaaaattataaagtaatttattatttattgtcaggagacttgccacttttcatgtcatttgacatttctttttgtttgctgaagtaaaaaaaaagataaaggttgtaccgtggtctttgaattatatgtctaattttatgtgttttgtcttttttttctttaaatattatgtgaaatcaaagcgccatatgtagaattatatcttcaggactatttcactaataaacgtttggcatagataattaaataaacgcga
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Creative Commons Attribution 4.0 International License (CC BY 4.0).
If you use GGRNA in your work, please cite:
Naito Y, Bono H. (2012)
GGRNA: an ultrafast, transcript-oriented search engine for genes and transcripts.
Nucleic Acids Res., 40, W592-W596.
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