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Previous release (v1)
2026-10-15 05:16:50, GGRNA.v2 : RefSeq release 233 (Jan, 2026)
LOCUS NM_001400930 4617 bp mRNA linear ROD 01-APR-2024
DEFINITION Rattus norvegicus kinesin family member 4A (Kif4a), mRNA.
ACCESSION NM_001400930 XM_006257113
VERSION NM_001400930.1
KEYWORDS RefSeq; RefSeq Select.
SOURCE Rattus norvegicus (Norway rat)
ORGANISM Rattus norvegicus
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
Muroidea; Muridae; Murinae; Rattus.
REFERENCE 1 (bases 1 to 4617)
AUTHORS Heintz,T.G., Heller,J.P., Zhao,R., Caceres,A., Eva,R. and
Fawcett,J.W.
TITLE Kinesin KIF4A transports integrin beta1 in developing axons of
cortical neurons
JOURNAL Mol Cell Neurosci 63, 60-71 (2014)
PUBMED 25260485
REMARK GeneRIF: Knockdown of KIF4A expression with shRNA reduced the level
of integrin beta1 in axons of developing neurons.
REFERENCE 2 (bases 1 to 4617)
AUTHORS Ghosh,D., Lippert,D., Krokhin,O., Cortens,J.P. and Wilkins,J.A.
TITLE Defining the membrane proteome of NK cells
JOURNAL J Mass Spectrom 45 (1), 1-25 (2010)
PUBMED 19946888
REFERENCE 3 (bases 1 to 4617)
AUTHORS Bisbal,M., Wojnacki,J., Peretti,D., Ropolo,A., Sesma,J., Jausoro,I.
and Caceres,A.
TITLE KIF4 mediates anterograde translocation and positioning of
ribosomal constituents to axons
JOURNAL J Biol Chem 284 (14), 9489-9497 (2009)
PUBMED 19158085
REMARK GeneRIF: KIF4 is involved in the anterograde trafficking of
ribosomal constituents to axons
REFERENCE 4 (bases 1 to 4617)
AUTHORS Zhu,C., Zhao,J., Bibikova,M., Leverson,J.D., Bossy-Wetzel,E.,
Fan,J.B., Abraham,R.T. and Jiang,W.
TITLE Functional analysis of human microtubule-based motor proteins, the
kinesins and dyneins, in mitosis/cytokinesis using RNA interference
JOURNAL Mol Biol Cell 16 (7), 3187-3199 (2005)
PUBMED 15843429
REFERENCE 5 (bases 1 to 4617)
AUTHORS Skop,A.R., Liu,H., Yates,J. 3rd, Meyer,B.J. and Heald,R.
TITLE Dissection of the mammalian midbody proteome reveals conserved
cytokinesis mechanisms
JOURNAL Science 305 (5680), 61-66 (2004)
PUBMED 15166316
REFERENCE 6 (bases 1 to 4617)
AUTHORS Sekine,Y., Okada,Y., Noda,Y., Kondo,S., Aizawa,H., Takemura,R. and
Hirokawa,N.
TITLE A novel microtubule-based motor protein (KIF4) for organelle
transports, whose expression is regulated developmentally
JOURNAL J Cell Biol 127 (1), 187-201 (1994)
PUBMED 7929562
COMMENT VALIDATED REFSEQ: This record has undergone validation or
preliminary review. The reference sequence was derived from
JAXUCZ010000021.1.
On Jan 28, 2022 this sequence version replaced XM_006257113.4.
##Evidence-Data-START##
Transcript exon combination :: SRR26643298.32165.1,
SRR26643292.65549.1 [ECO:0000332]
RNAseq introns :: single sample supports all introns
SAMEA5760383, SAMEA5760389
[ECO:0000348]
##Evidence-Data-END##
##RefSeq-Attributes-START##
RefSeq Select criteria :: based on conservation, expression,
longest protein
##RefSeq-Attributes-END##
COMPLETENESS: full length.
PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP
1-70 JAXUCZ010000021.1 69761883-69761952
71-380 JAXUCZ010000021.1 69762072-69762381
381-495 JAXUCZ010000021.1 69762499-69762613
496-686 JAXUCZ010000021.1 69771815-69772005
687-779 JAXUCZ010000021.1 69774031-69774123
780-946 JAXUCZ010000021.1 69776714-69776880
947-1041 JAXUCZ010000021.1 69777102-69777196
1042-1158 JAXUCZ010000021.1 69799140-69799256
1159-1334 JAXUCZ010000021.1 69800091-69800266
1335-1396 JAXUCZ010000021.1 69804341-69804402
1397-1529 JAXUCZ010000021.1 69812297-69812429
1530-1588 JAXUCZ010000021.1 69814926-69814984
1589-1694 JAXUCZ010000021.1 69815090-69815195
1695-1751 JAXUCZ010000021.1 69820583-69820639
1752-1937 JAXUCZ010000021.1 69822014-69822199
1938-2041 JAXUCZ010000021.1 69822745-69822848
2042-2186 JAXUCZ010000021.1 69823947-69824091
2187-2297 JAXUCZ010000021.1 69825630-69825740
2298-2381 JAXUCZ010000021.1 69834823-69834906
2382-2495 JAXUCZ010000021.1 69835574-69835687
2496-2651 JAXUCZ010000021.1 69842844-69842999
2652-2752 JAXUCZ010000021.1 69843114-69843214
2753-2882 JAXUCZ010000021.1 69844908-69845037
2883-3053 JAXUCZ010000021.1 69846508-69846678
3054-3161 JAXUCZ010000021.1 69847181-69847288
3162-3239 JAXUCZ010000021.1 69848376-69848453
3240-3338 JAXUCZ010000021.1 69848966-69849064
3339-3515 JAXUCZ010000021.1 69849548-69849724
3516-3632 JAXUCZ010000021.1 69861412-69861528
3633-3755 JAXUCZ010000021.1 69863159-69863281
3756-4617 JAXUCZ010000021.1 69863474-69864335
FEATURES Location/Qualifiers
source 1..4617
/organism="Rattus norvegicus"
/mol_type="mRNA"
/strain="BN"
/db_xref="taxon:10116"
/chromosome="X"
/map="Xq22"
gene 1..4617
/gene="Kif4a"
/gene_synonym="Kif4"
/note="kinesin family member 4A"
/db_xref="GeneID:84393"
/db_xref="RGD:620526"
exon 1..70
/gene="Kif4a"
/gene_synonym="Kif4"
/inference="alignment:Splign:2.1.0"
exon 71..380
/gene="Kif4a"
/gene_synonym="Kif4"
/inference="alignment:Splign:2.1.0"
misc_feature 249..251
/gene="Kif4a"
/gene_synonym="Kif4"
/note="upstream in-frame stop codon"
CDS 261..3956
/gene="Kif4a"
/gene_synonym="Kif4"
/note="kinesin heavy chain member 4; kinesin family member
4"
/codon_start=1
/product="chromosome-associated kinesin KIF4A"
/protein_id="NP_001387859.1"
/db_xref="GeneID:84393"
/db_xref="RGD:620526"
/translation="
MKEEVKGIPVRVALRCRPLVSKEINEGCQTCLSFVPGEPQVVVGTDKSFTYDFVFDPSTEQEEVFNTAVAPLIKGVFKGYNATVLAYGQTGSGKTYSMGGAYTAEQEHDSAIGVIPRVIQLLFKEINKKTDFEFTLKVSYLEIYNEEILDLLCSSREKASQINIREDPKEGIKIVGLTEKTVLVASDTVSCLEQGNNCRTVASTAMNSQSSRSHAIFTISIEQRKKNDKNSSFRSKLHLVDLAGSERQKKTKAEGDRLKEGININRGLLCLGNVISALGDDKKGNFVPYRDSKLTRLLQDSLGGNSHTLMIACVSPADSNLEETLNTLRYADRARKIKNKPIINIDPQAAELNHLKQQVQQLQVLLLQAHGGTLPGNINVKPSENLQSLMEKNQSLVEENEKLSRGLSEAAGQTAQMLERIILTEQANEKMNAKLEELRQHAACKVDLQKLAETLEDQEVKENIEIICNLQQAIARLSDEAVACMTATIDTAGEVDTQEQSSPDTSRSSDVFSTQHALRQAQMSKELIELNKELALKEALAKKMTQNDNQLQPIQFQYQDNIKNLELEVLSLQKEKEELVLELQTAKKDVNQAKLSERRRKRLQELEGQIAELKKKLHEQSKLLKLKETTELTVSKLNQEIRMMKNQRVQLMRQMKEDAEKFRQWKQQKDKEVIQLKERDRKRQYELLKLERNFQKQSNVLRRKTEEAAAANKRLKDALQKQKEVAEKRKETQSRGMEGTAARMKSWLGNEIEVMVSTEEAKRHLNDLLEERKILAQDVAQLKEKRESGENPPPKLRRRTFSRDEVHGQDSGAEDSISKQIESLESELELRSAQIADLQQKLLDAESEDQPKQRWENIATILEAKCAIKYLVGELVSSKIQVSKLESGLSQSKASCIEVQKMLFEEQNHFAKIETELKEELVRVEQQHQEKVLYLLSQLQQCQVTEKQLEESVSEKEQQLLSTLKCQEEELRKMQEVCEQNQQLLQENSAIKQKLNLLQVVSKEKPHLVRNILQSPDSSFEYIPPKPKPFRIKEKCPEKSFAIEDLQYYSETSVAEEENEDSDDHADEEWIPTKLVKVSKKNIQGCSCKGWCGNKQCGCRKQKSDCNGACSCDPTKCRNRHHSQDNSDVIELNQDSENSFKLEDPTEVTSGLSFFNPVCTTPSSKILKEMCDADQVLLRQPDFASSSDHLELKPIASETQENKAMGKKKKRALASNTSFFSGCSPIQEESH"
misc_feature 282..1274
/gene="Kif4a"
/gene_synonym="Kif4"
/note="Kinesin motor domain, KIF4-like subfamily; Region:
KISc_KIF4; cd01372"
/db_xref="CDD:276823"
misc_feature order(309..311,522..524,531..533,537..548,981..983)
/gene="Kif4a"
/gene_synonym="Kif4"
/note="ATP binding site [chemical binding]; other site"
/db_xref="CDD:276823"
misc_feature order(1128..1130,1137..1139,1146..1148)
/gene="Kif4a"
/gene_synonym="Kif4"
/note="microtubule interaction site [polypeptide binding];
other site"
/db_xref="CDD:276823"
misc_feature <1449..3377
/gene="Kif4a"
/gene_synonym="Kif4"
/note="MAEBL; Provisional; Region: PTZ00121"
/db_xref="CDD:173412"
misc_feature 1908..>2855
/gene="Kif4a"
/gene_synonym="Kif4"
/note="chromosome segregation protein SMC, common
bacterial type; Region: SMC_prok_B; TIGR02168"
/db_xref="CDD:274008"
misc_feature 3510..>3623
/gene="Kif4a"
/gene_synonym="Kif4"
/note="SET (Su(var)3-9, Enhancer-of-zeste, Trithorax)
domain superfamily; Region: SET; cl40432"
/db_xref="CDD:394802"
exon 381..495
/gene="Kif4a"
/gene_synonym="Kif4"
/inference="alignment:Splign:2.1.0"
exon 496..686
/gene="Kif4a"
/gene_synonym="Kif4"
/inference="alignment:Splign:2.1.0"
exon 687..779
/gene="Kif4a"
/gene_synonym="Kif4"
/inference="alignment:Splign:2.1.0"
exon 780..946
/gene="Kif4a"
/gene_synonym="Kif4"
/inference="alignment:Splign:2.1.0"
exon 947..1041
/gene="Kif4a"
/gene_synonym="Kif4"
/inference="alignment:Splign:2.1.0"
exon 1042..1158
/gene="Kif4a"
/gene_synonym="Kif4"
/inference="alignment:Splign:2.1.0"
exon 1159..1334
/gene="Kif4a"
/gene_synonym="Kif4"
/inference="alignment:Splign:2.1.0"
exon 1335..1396
/gene="Kif4a"
/gene_synonym="Kif4"
/inference="alignment:Splign:2.1.0"
exon 1397..1529
/gene="Kif4a"
/gene_synonym="Kif4"
/inference="alignment:Splign:2.1.0"
exon 1530..1588
/gene="Kif4a"
/gene_synonym="Kif4"
/inference="alignment:Splign:2.1.0"
exon 1589..1694
/gene="Kif4a"
/gene_synonym="Kif4"
/inference="alignment:Splign:2.1.0"
exon 1695..1751
/gene="Kif4a"
/gene_synonym="Kif4"
/inference="alignment:Splign:2.1.0"
exon 1752..1937
/gene="Kif4a"
/gene_synonym="Kif4"
/inference="alignment:Splign:2.1.0"
exon 1938..2041
/gene="Kif4a"
/gene_synonym="Kif4"
/inference="alignment:Splign:2.1.0"
exon 2042..2186
/gene="Kif4a"
/gene_synonym="Kif4"
/inference="alignment:Splign:2.1.0"
exon 2187..2297
/gene="Kif4a"
/gene_synonym="Kif4"
/inference="alignment:Splign:2.1.0"
exon 2298..2381
/gene="Kif4a"
/gene_synonym="Kif4"
/inference="alignment:Splign:2.1.0"
exon 2382..2495
/gene="Kif4a"
/gene_synonym="Kif4"
/inference="alignment:Splign:2.1.0"
exon 2496..2651
/gene="Kif4a"
/gene_synonym="Kif4"
/inference="alignment:Splign:2.1.0"
exon 2652..2752
/gene="Kif4a"
/gene_synonym="Kif4"
/inference="alignment:Splign:2.1.0"
exon 2753..2882
/gene="Kif4a"
/gene_synonym="Kif4"
/inference="alignment:Splign:2.1.0"
exon 2883..3053
/gene="Kif4a"
/gene_synonym="Kif4"
/inference="alignment:Splign:2.1.0"
exon 3054..3161
/gene="Kif4a"
/gene_synonym="Kif4"
/inference="alignment:Splign:2.1.0"
exon 3162..3239
/gene="Kif4a"
/gene_synonym="Kif4"
/inference="alignment:Splign:2.1.0"
exon 3240..3338
/gene="Kif4a"
/gene_synonym="Kif4"
/inference="alignment:Splign:2.1.0"
exon 3339..3515
/gene="Kif4a"
/gene_synonym="Kif4"
/inference="alignment:Splign:2.1.0"
exon 3516..3632
/gene="Kif4a"
/gene_synonym="Kif4"
/inference="alignment:Splign:2.1.0"
exon 3633..3755
/gene="Kif4a"
/gene_synonym="Kif4"
/inference="alignment:Splign:2.1.0"
exon 3756..4617
/gene="Kif4a"
/gene_synonym="Kif4"
/inference="alignment:Splign:2.1.0"
ORIGIN
gaaacttggcggttaaagctccggttggaacagggcgccagggaagatcggggaagggacgtttagtttgtattgggactgacaaaccattaggcggtggccaagagtgacaggacacagtgatcctgctgggagggagagtgcatcagcgagttccgagtctcctacggcctgagaagggcctttctactcctgccaacctcggaaggttcctgggagagctggcttcacttggccaggacacctgctgagctggtaccatgaaagaagaggtgaagggaattcctgtaagagtggcactgcgttgtcgcccccttgtctctaaagagattaatgagggctgccagacgtgcctttcttttgtgcccggagagcctcaggtggtggttggtactgataaatcatttacctacgattttgtgtttgacccctctactgaacaggaagaggtctttaatacagcagtagctccactcataaaaggcgtgtttaaaggatacaatgcaactgtcctggcctatgggcagactggatctgggaagacttattcaatgggaggtgcatacactgcagaacaagaacatgactcagccattggggttattcccagggtaatacaactgctcttcaaagaaattaataaaaagactgactttgaatttactctgaaagtgtcttacttggagatttataatgaagaaattttggaccttctatgttcatctcgtgagaaagcatctcaaataaatatccgggaggatcctaaggaaggcataaagattgtgggactgacggagaagactgtgctagttgcctcggacactgtttcctgtctagagcagggtaacaactgcaggactgtggcctccacagctatgaactcccagtcatctcggtctcatgccatctttacaatctccatcgagcaaaggaagaaaaatgacaaaaatagcagtttccgttccaagctgcatcttgtagaccttgctggatcagaaagacagaagaaaaccaaggccgagggagatcgtctgaaagagggtattaatatcaatcgaggccttctgtgcttgggaaatgtaattagtgctcttggagatgacaaaaagggtaactttgtgccctacagagattccaagctgactcgactgcttcaagattctctaggaggcaatagccatactcttatgatcgcctgtgtgagtcctgctgattccaacctagaggaaacattaaatacccttcgctatgctgacagagcaagaaaaatcaagaacaaacctattattaatattgatccccaggcagctgaactaaatcaccttaaacaacaggtccaacagctgcaggtcttgttgctacaagcccatggaggcaccttgcctgggaatataaatgtgaaaccatcagaaaacctccagtccctgatggagaagaatcagtctctggtggaagagaatgaaaaattaagtcgtggtctgagtgaggcagctggtcagacagcccagatgttggagaggatcattttgactgagcaagcaaatgagaaaatgaatgccaagctagaagaactcagacagcatgcagcctgcaaagtggatcttcaaaagctagcagaaacattggaagaccaggaagtaaaagaaaacatagagatcatttgcaacctacaacaagcgattgcccggttgtctgatgaagcggttgcttgcatgactgcaaccatcgatactgcaggggaagtagacactcaagagcaaagcagtccagataccagcaggtcttctgatgttttcagcactcaacatgctctccgtcaagctcagatgtccaaggagctgattgagttgaataaagaacttgcattgaaagaagccctagctaagaagatgacccagaatgacaaccagctacagcccattcagttccagtaccaggataatattaaaaatctagaattggaagtcctcagtctacagaaggaaaaagaagaattggttcttgaacttcaaacagcaaagaaggatgtcaaccaagccaagttgagcgaacgccgtcgcaaacgtcttcaggagctggagggtcaaatagctgagttgaaaaagaaacttcatgaacagtccaaacttctgaagctgaaggaaaccactgagcttactgtctccaagctgaaccaggagatacggatgatgaaaaaccagcgagtccagttaatgcgtcaaatgaaagaggatgctgagaagtttaggcagtggaagcaacaaaaagacaaagaagtaatccagctaaaagaacgggatcgtaaaaggcaatacgaactgctcaaacttgaaagaaacttccagaaacagtctaatgtgctcagacgtaaaactgaggaggcagcagctgctaacaaacgtcttaaggatgctctccaaaagcaaaaggaggttgcagaaaaacggaaagagacccagagccgtggaatggaaggcactgcagctcgaatgaagagttggcttggaaatgaaatcgaggttatggtcagtaccgaggaagccaaaaggcatctgaatgaccttcttgaagagagaaagatccttgctcaggatgtggcacaactcaaagaaaaaagagaatctggagagaatccacctcctaaactccgaaggcgcacattctcacgagatgaagtgcatggtcaagattcaggagcagaggattctatttcaaagcagattgaaagcctggagagtgaattggagctcaggagtgctcagattgcagacctacagcaaaagcttctggatgctgaaagtgaagaccagccaaaacaacgctgggagaatattgccacgattctcgaagccaaatgtgccataaagtatttagttggagagctggtctcctccaaaatacaggtgagcaaactggaaagcggcctgagtcagagcaaggccagctgtattgaagtgcagaagatgctgtttgaggaacaaaatcattttgctaaaatagagaccgagttgaaagaagagctggtcagagtggagcagcagcaccaggaaaaggtgttgtaccttctcagtcagctgcagcaatgccaagtgacagagaaacagctggaggagtcggttagtgagaaggaacagcagctgctgagcaccctgaaatgtcaggaggaagagcttaggaagatgcaagaagtgtgtgagcaaaatcagcagcttctgcaagaaaacagtgccatcaagcagaaactgaacctcctccaagtagtcagcaaagagaaaccccatcttgtgagaaatatcctccagtctccggactcttcctttgaatatattccacctaagcccaaacctttccgtattaaagaaaaatgcccagagaaaagcttcgccatcgaggacctgcagtattattcagagacttctgtggctgaggaggagaatgaggacagtgatgaccatgctgatgaggagtggatcccaacaaaattagtcaaggtgtccaagaagaacatccaagggtgttcctgcaaaggctggtgtgggaacaagcaatgtggatgcagaaagcaaaagtcagactgtaatggggcctgcagctgtgaccccacaaaatgccgcaaccgccatcacagccaggacaactcagatgttattgagctaaaccaagattctgaaaactccttcaaactggaagatcccacagaggtgacctcaggattaagcttcttcaaccctgtttgtacgactcccagtagcaagatcctaaaagaaatgtgtgatgcagatcaggtgctgctgaggcagcctgattttgcctcttcctctgaccatctagaactgaaacctattgcatcagaaacacaagaaaataaggccatggggaagaagaagaagcgagctctagccagcaataccagcttcttctctggctgctcccctattcaagaagagtcccactgaggttagggccactgtctcttctgtctgccctggacacactctgaggctgcagcacagaggggaagggcactaatgacttctgtagcttttaggtcctgctattgagaaaaggagaataagtccctgaaaggaagagggcctctactgtctaagctctctgcctacaaaaactactttgcttctttagaaggtgctgaaccttctactggagagagaaccaactgaccttcctgatactcaagaggaaccagtccccaggacagtctagctcgctctctgtgagcagttgagttgtatcttcatggagtcgaggtcaacatgttcttctcttatgatcacatcagcttaatggacgagtgggatggtgacctggctcgactccgtcaccacacctcaggaattgggcagggagcttccctgctccattccaactccggactttacaaacccttcaactgtccgtcacccatgttactgaagtgaatgaaacattttaaaaatgttaaaataaataaaccttagctcatctactatttgaaggagatccttctatgctagaggaagaagtaaaattccaacatgttttcttcagcccctgggaagtcttaaagcatccatttcagtttccccacaaatacacatacctcctttttctgggaaa
//
by
@meso_cacase at
DBCLS
This page is licensed under a
Creative Commons Attribution 4.0 International License (CC BY 4.0).
If you use GGRNA in your work, please cite:
Naito Y, Bono H. (2012)
GGRNA: an ultrafast, transcript-oriented search engine for genes and transcripts.
Nucleic Acids Res., 40, W592-W596.
[Full Text]