LOCUS       NM_001033062            1739 bp    mRNA    linear   ROD 21-MAR-2023
DEFINITION  Rattus norvegicus claudin 23 (Cldn23), mRNA.
ACCESSION   NM_001033062 XM_224915
VERSION     NM_001033062.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1739)
  AUTHORS   De Benedetto A, Rafaels NM, McGirt LY, Ivanov AI, Georas SN,
            Cheadle C, Berger AE, Zhang K, Vidyasagar S, Yoshida T, Boguniewicz
            M, Hata T, Schneider LC, Hanifin JM, Gallo RL, Novak N, Weidinger
            S, Beaty TH, Leung DY, Barnes KC and Beck LA.
  TITLE     Tight junction defects in patients with atopic dermatitis
  JOURNAL   J Allergy Clin Immunol 127 (3), 773-86 (2011)
   PUBMED   21163515
REFERENCE   2  (bases 1 to 1739)
  AUTHORS   Krause G, Winkler L, Mueller SL, Haseloff RF, Piontek J and Blasig
            IE.
  TITLE     Structure and function of claudins
  JOURNAL   Biochim Biophys Acta 1778 (3), 631-645 (2008)
   PUBMED   18036336
  REMARK    Review article
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC100630.1.
            
            On Sep 9, 2005 this sequence version replaced XM_224915.1.
            
            ##Evidence-Data-START##
            Transcript is intronless :: BC100630.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1739
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="16"
                     /map="16q12.2"
     gene            1..1739
                     /gene="Cldn23"
                     /note="claudin 23"
                     /db_xref="GeneID:290789"
                     /db_xref="RGD:1309001"
     exon            1..1725
                     /gene="Cldn23"
                     /inference="alignment:Splign:2.1.0"
     misc_feature    43..45
                     /gene="Cldn23"
                     /note="upstream in-frame stop codon"
     CDS             103..990
                     /gene="Cldn23"
                     /codon_start=1
                     /product="claudin-23"
                     /protein_id="NP_001028234.1"
                     /db_xref="GeneID:290789"
                     /db_xref="RGD:1309001"
                     /translation="

MRTPVVMTLGMVLTPCGLLLNLVSTLAPGWRLLKGFRDQPVDVVLYQGLWDICREQSSRERECGQPDQWNYFGTQPVQVARGLMITSLATTALGLLLASLGVRCWQEEPHFGLAGLSGVVLFAAGLFSLIPVSWYNHFLADPDVLAAPAQPVTVQVSYSLVLGYLGSCLLLLGGFSLALSFAPWCEERCCRCRKAPPAGPRRSSISTVYVDWPEPALTPAIKYYSEGQHRPPPAQQRDTGKLKVGFPMPRPPPKAYTNPMDVLEGEEKKTASSQDGSSSRSTRPCQNSLPCDSDL"

     misc_feature    115..>513
                     /gene="Cldn23"
                     /note="PMP-22/EMP/MP20/Claudin family; Region:
                     PMP22_Claudin; cl21598"
                     /db_xref="CDD:451326"
ORIGIN      

cggtgagcatcgctgccacccagcccggcaacctcgcagacttgaggacccggtgcgccgcggagcagccacagctgctggggacccacgaggctacgcgggatgcggacgccggtggtgatgacgctgggcatggtgctcacgccctgtgggttgctgctcaatctcgtcagtacactggccccgggctggcggctgttgaagggctttcgggaccagccagtggacgtggtgctgtaccaggggctgtgggacatatgtcgcgagcagagcagccgcgagcgcgagtgcggccagccggaccagtggaactacttcgggactcagcctgtgcaggtggcccggggactcatgatcacttcactggccactaccgccctagggctgctgttggcttcgctcggcgtgcgctgttggcaagaagagccccacttcgggctagcgggcctctcgggggttgtgcttttcgccgccggcctcttcagcctcatccccgtctcctggtataaccacttcttggcagatcctgacgtcctggctgccccggcccaaccggtcactgtgcaggtcagctacagtctggtgctgggctacctaggcagttgcctgctgttgttgggcggtttctcgctggcgctcagctttgcgccctggtgtgaagagcgttgttgccgctgtcgcaaggcgcccccagcaggcccacgccgcagcagcatcagcaccgtctacgtggactggccggaacccgcactcacacccgccatcaagtactacagcgagggtcagcatcgacctcctcctgcccagcaaagggacaccggcaaactcaaggtcggattcccgatgccacgaccgccacccaaggcctacaccaacccgatggatgtgcttgagggagaagaaaagaagacagcctcctcccaagacggttcctcatctcgcagcactcggccctgccaaaattcgctgccctgtgactccgacctgtagacagggctcaactgagctccacctgtggtctgagggtgacttgaacttctacatggccagtacatctgcaaccagaaccctggacgccttcctctaactggagggcaagccttcctttcctggccaagctcctctccagatactaggttgggttcatttatcttttaaggagttttactttttctctgcagagggaccaggttttctgtgacaagagtgggtggcattttgcatagtgttaattgcagtagcaacaacaaaatctcaatcagccaacaggctttaagaagtccttgaaaatacagtattctaagttacccatgagccttcacaaacatcactcttgaggtgtttggtttggttttgcttttgtccctgcttcagtctccagtgaacccaaatggccaaaaatgtaagtctggctgtatttgaaggttgtgccacaaagccagctgccttaatgtcttttatgaagtgaagtaacttgttaacacatatttatatttctctgtgcatacatagtatttatcttttctaatcacttgtttctgtgtaggaggttgagcttagtcaagagattgccttccagaagccaggacgatgctacgctgtcctgttccctagatacctcaccctgaacagagagacacattttgtacaaaatgaactgctaagctgcattggctaaagcccgtatgtacatatcttatttataaataaaaattgtaaatgtcaaaaaaaaaaaaaaa

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