LOCUS       NM_001009487            1411 bp    mRNA    linear   ROD 21-MAR-2023
DEFINITION  Rattus norvegicus Ly49 stimulatory receptor 4 (Ly49s4), transcript
            variant 1, coding, mRNA.
ACCESSION   NM_001009487 XM_579288
VERSION     NM_001009487.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1411)
  AUTHORS   Kveberg L, Dai KZ, Dissen E, Ryan JC, Rolstad B, Vaage JT and Naper
            C.
  TITLE     Strain-dependent expression of four structurally related rat Ly49
            receptors; correlation with NK gene complex haplotype and NK
            alloreactivity
  JOURNAL   Immunogenetics 58 (11), 905-916 (2006)
   PUBMED   17028855
REFERENCE   2  (bases 1 to 1411)
  AUTHORS   Nylenna O, Naper C, Vaage JT, Woon PY, Gauguier D, Dissen E, Ryan
            JC and Fossum S.
  TITLE     The genes and gene organization of the Ly49 region of the rat
            natural killer cell gene complex
  JOURNAL   Eur J Immunol 35 (1), 261-272 (2005)
   PUBMED   15593300
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AY649831.1.
            
            On Apr 19, 2005 this sequence version replaced XM_579288.1.
            
            Transcript Variant: This variant (1, coding) represents the
            functional allele that is not present in some strains, including
            the strain of the reference genome.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY649831.1 [ECO:0000332]
            RNAseq introns              :: mixed/partial sample support
                                           SAMEA5760434, SAMN06680442
                                           [ECO:0000350]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            polymorphic pseudogene :: based on alignments, homology
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1411
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="PVG"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /map="4q42"
     gene            1..1411
                     /gene="Ly49s4"
                     /note="Ly49 stimulatory receptor 4"
                     /db_xref="GeneID:494195"
                     /db_xref="RGD:1549723"
     exon            1..82
                     /gene="Ly49s4"
                     /inference="alignment:Splign:2.1.0"
     exon            83..249
                     /gene="Ly49s4"
                     /inference="alignment:Splign:2.1.0"
     misc_feature    108..110
                     /gene="Ly49s4"
                     /note="upstream in-frame stop codon"
     CDS             138..971
                     /gene="Ly49s4"
                     /codon_start=1
                     /product="Ly49 stimulatory receptor 4"
                     /protein_id="NP_001009487.1"
                     /db_xref="GeneID:494195"
                     /db_xref="RGD:1549723"
                     /translation="

MSKQDVPCSTVRFKKSSGLWYQVRPEETQRPRETGCRVPWQLTVIGIGILLSLRLVAVAMLLTNIFQYSNENHELQKTQNRHHNCSTMEKDIKLKEEILRTMSAESVHYNALLDLINREQNRWYKKTKTVLASPQRTGGCDEMHWFCYGIKCYYFTMDIRIWRECKQTCQNYSLSFLKIDVKDELKFLQDHIIRDNYWIGSSYNNKKKEWSWIDNSPFNLDFVARNSLRKTGYCMYFSMAGLHDDDCGKRYLCICEKGMDKIPAPLCSVKERSHSAV"

     misc_feature    249..602
                     /gene="Ly49s4"
                     /note="Ly49-like protein, N-terminal region; Region: Ly49;
                     pfam08391"
                     /db_xref="CDD:429969"
     misc_feature    561..908
                     /gene="Ly49s4"
                     /note="C-type lectin-like domain (CTLD) of the type found
                     in natural killer cell receptors (NKRs); Region:
                     CLECT_NK_receptors_like; cd03593"
                     /db_xref="CDD:153063"
     misc_feature    order(723..725,807..809,858..860,864..869)
                     /gene="Ly49s4"
                     /note="ligand binding surface [chemical binding]; other
                     site"
                     /db_xref="CDD:153063"
     exon            250..330
                     /gene="Ly49s4"
                     /inference="alignment:Splign:2.1.0"
     exon            331..549
                     /gene="Ly49s4"
                     /inference="alignment:Splign:2.1.0"
     exon            550..692
                     /gene="Ly49s4"
                     /inference="alignment:Splign:2.1.0"
     exon            693..796
                     /gene="Ly49s4"
                     /inference="alignment:Splign:2.1.0"
     exon            797..1394
                     /gene="Ly49s4"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      

atacacaccaggaaaggtcaaggctttctctaattgggagaagagtaccttccaacagaatcactttgggatagagacacagaaaaaactcaaggcctgattttaactgaaaacagacttcatacatcattcccaaaatgagtaagcaggatgttccttgctcaactgtgagatttaaaaagtcttcagggttgtggtatcaagtgaggcctgaggagactcaaaggcccagggaaactggctgcagagtcccctggcagctcactgtgattggtattggaatcctcctttcccttcgactggttgctgttgcaatgttgctgacaaacatttttcagtacagtaatgaaaaccatgaactacagaaaactcaaaaccgtcaccataactgcagcaccatggaaaaggacatcaaattaaaggaagaaatactgagaactatgtctgcagagagtgttcactacaatgctcttctggacttaatcaacagagaacagaacagatggtacaagaaaactaagactgttttagcttcccctcagcgcacaggcgggtgtgatgaaatgcactggttctgctatggtataaaatgttattatttcaccatggatataaggatatggcgtgaatgtaaacagacctgtcagaactacagcttgtcctttctgaagatagatgttaaggatgaactgaagttccttcaggaccacattattcgtgacaattactggattggatcatcatataataacaaaaaaaaggaatggtcatggattgacaacagcccatttaatcttgattttgtggcaaggaattcgctacgaaaaacaggatactgtatgtatttcagtatggcaggtctacatgatgatgactgtggtaaaagatatctctgtatctgtgaaaagggaatggacaaaatccctgccccattgtgcagtgtgaaggaaaggtcacattctgctgtgtgaatagagagatgagctgcaaagggaagaagtcttcttaaatttggcataagagcagacacagtattccctcttggcacatggagcagcttgcatgtggagaatggacatccttttttccaagacccaaacgattccctcacattgtctcctgaatgacacacagaaccacatggagaactcaatacataatgcacacatcacatcttctttaggatatttctatagcccttggctgatagcacaattaatgactaatctgctgttgtgggttttcatatattggttagttgctatttggtatttttttttgatgtacaaaaagttagcattttaaaatccttttgagacgaggatctgtggaagggagggctggagggggtgatgaccggactgttaataaataaaataattttgaaaaccttaaaaaaaaaaaaaaaaaa

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