LOCUS       XM_006497997           10194 bp    mRNA    linear   ROD 07-FEB-2024
DEFINITION  PREDICTED: Mus musculus RAB GTPase activating protein 1 (Rabgap1),
            transcript variant X2, mRNA.
ACCESSION   XM_006497997
VERSION     XM_006497997.5
DBLINK      BioProject: PRJNA169
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000068.8) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Sep 21, 2020 this sequence version replaced XM_006497997.4.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001635.27-RS_2024_02
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.2
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 02/01/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10194
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6J"
                     /db_xref="taxon:10090"
                     /chromosome="2"
     gene            1..10194
                     /gene="Rabgap1"
                     /gene_synonym="Gapcena; mKIAA4104"
                     /note="RAB GTPase activating protein 1; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 4 mRNAs, 12 ESTs, 673 long SRA reads, 3 Proteins, and
                     99% coverage of the annotated genomic feature by RNAseq
                     alignments, including 36 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:227800"
                     /db_xref="MGI:MGI:2385139"
     CDS             246..2723
                     /gene="Rabgap1"
                     /gene_synonym="Gapcena; mKIAA4104"
                     /codon_start=1
                     /product="rab GTPase-activating protein 1 isoform X2"
                     /protein_id="XP_006498060.1"
                     /db_xref="GeneID:227800"
                     /db_xref="MGI:MGI:2385139"
                     /translation="

MDDKASVGKISVSSDSVSTLNSEDFVLVSRQGDETPSTNNGSDDEKTGLKIVGNGSEQQLQKELADVLMDPPMDDQPGERSQLDGEGDGPLSNQLSASSTINPVPLVGLPKPEMSLPVKPGQGDSEVSSPFTPVADEDSVVFNKLTYLGCASVNAPRSEVEALRMMSILRSQCQISLDVTLSVPNVSEGTVRLLDPQTNTEIANYPIYKILFCVRGHDGTPESDCFAFTESHYNAELFRIHVFRCEIQEAVSRILYSFATAFRRSAKQTPLSATAAPQTPDSDIFTFSVSLEIKEDDGKGYFSAVPKDKDRQCFKLRQGIDKKIVICVQQTANKELAIERCFGLLLSPGKDVRNSDMHLLDLESMGKSSDGKSYVITGSWNPKSPHFQVVNEETPKDKVLFMTTAVDLVITEVQEPVRFLLETKVRVCSPNERLFWPFSKRSTTENFFLKLKQIKQKEKKNNADTLYEVVCLESESERERRKTTASPSVRLPQSGSQSSMIPSPPEDDEEEDNDEPLLSGFGDVSKECAEKILETWGELLSKWHLNLSVRPKQLSSLVRSGVPEALRGEVWQLLAGCHNNDHLVEKYRILITKESPQDSAITRDINRTFPAHDYFKDTGGDGQDSLYKICKAYSVYDEEIGYCQGQSFLAAVLLLHMPEEQAFSVLVKIMFDYGLRELFKQNFEDLHCKFYQLERLMQEYIPDLYNHFLDISLEAHMYASQWFLTLFTAKFPLYMVFHIIDLLLCEGISVIFNVALGLLKTSKDDLLLTDFEGALKFFRVQLPKRYRSEENAKRLMELACNTKNPAVAVEPLNHVSVEADISGMK"

     misc_feature    663..1049
                     /gene="Rabgap1"
                     /gene_synonym="Gapcena; mKIAA4104"
                     /note="GTPase activating protein for Rab 6
                     Phosphotyrosine-binding (PTB) domain; Region: PTB_Rab6GAP;
                     cd01211"
                     /db_xref="CDD:269922"
     misc_feature    order(681..683,915..917,975..977)
                     /gene="Rabgap1"
                     /gene_synonym="Gapcena; mKIAA4104"
                     /note="putative phosphoinositide binding site [chemical
                     binding]; other site"
                     /db_xref="CDD:269922"
     misc_feature    order(873..890,936..938,999..1001,1011..1013)
                     /gene="Rabgap1"
                     /gene_synonym="Gapcena; mKIAA4104"
                     /note="putative peptide binding site [polypeptide
                     binding]; other site"
                     /db_xref="CDD:269922"
     misc_feature    1149..1541
                     /gene="Rabgap1"
                     /gene_synonym="Gapcena; mKIAA4104"
                     /note="Kinesin protein; Region: DUF3694; pfam12473"
                     /db_xref="CDD:463599"
     misc_feature    1917..2546
                     /gene="Rabgap1"
                     /gene_synonym="Gapcena; mKIAA4104"
                     /note="Domain in Tre-2, BUB2p, and Cdc16p. Probable
                     Rab-GAPs; Region: TBC; smart00164"
                     /db_xref="CDD:214540"
ORIGIN      

gagggactttccgcgttgtgggcggggcgaggccagggaatcgggctgcggagggtcggcttcgtgagctctgctgcttgtggttcttcggtagaaggcgggcccgagctctcttcttcgcggctgcagtcacgaagtgctcccgctgaccgttgcctgcatgggcctgagcagcctgtctgcgaacaagccgtggcattaaaaaaatatttaaccattcatgagttgagcctcattcttgagttatggatgacaaggcctctgttggaaaaatcagtgtctcatcagactcagtgtctactcttaatagtgaagattttgtcttggtttccaggcaaggagatgagacaccatctacaaataatgggagtgatgatgagaagacgggactcaagattgtaggaaatggaagtgagcagcagcttcagaaagagctagcagatgtgctgatggatcctcccatggacgaccagccaggggaaaggtcacaactggatggtgaaggagatgggcctctttctaatcaactctcagcttcatccaccattaatcctgtgcctctggtagggcttccgaaaccagagatgagcctgccagtgaaacctggacaaggagattctgaagtatcaagtccttttacaccagtggctgatgaggatagtgtggttttcaataaactaacttacttaggctgtgcttcagtaaatgctccccggagtgaagtggaagccttgaggatgatgtccatcttgagaagtcagtgtcagatttctctggatgtaaccctctcagtgccgaatgtatctgaaggaactgtgagacttttagatcctcaaacaaacactgaaatagcaaactaccctatctacaaaatcctcttctgtgtcagaggacatgatgggactcctgagagtgactgttttgcattcactgaaagtcactacaacgcagagctcttcaggatacatgtctttcgctgtgaaatacaagaagctgtgagccggatactttacagttttgccaccgccttccgccgctctgccaagcagaccccactctcagccacagctgcaccacagactcctgacagcgacatctttaccttctctgtgtctttagaaataaaagaagatgatggtaaaggttattttagtgctgttcccaaagacaaggacaggcaatgctttaaacttcgacaaggaattgataagaagattgttatctgtgtgcagcaaacagctaacaaagaacttgccattgaaaggtgctttggtcttctccttagcccaggaaaagatgtccgaaacagtgatatgcacttgctggatttggagtctatgggcaaaagttcagatggaaaatcatatgttattactggaagctggaacccgaaatccccacattttcaagttgtgaatgaagaaactcctaaagataaagtgctgttcatgacaacagctgtggatttggtgataactgaagtacaggaacctgttcgatttcttctagagacaaaagttcgagtgtgctcacctaatgaaaggttattctggcccttcagcaaacgaagcactactgaaaacttctttctgaaactgaagcagataaagcaaaaggagaaaaagaataatgctgacactttatatgaagttgtgtgtttggagagtgagtcagagagagagaggaggaaaaccacagccagtccttcagttcgcctgccacagtctggatcccagagctccatgatcccctctcccccagaagatgatgaagaagaagataatgatgaacctctcttgagtggatttggggatgtatccaaagaatgtgcagaaaaaattcttgaaacatggggagaactgctgtcaaaatggcatctcaacttgagtgtgagaccgaagcagttgtcatccttagtgagaagtggtgttcctgaagctcttcgtggagaagtctggcagctgctagcaggctgccacaacaacgatcacttagtagaaaagtaccgaattctcatcacaaaggagtctcctcaagacagtgctatcaccagagatattaaccgcacatttccagctcatgactacttcaaggacacaggaggagatggacaagattctttatataaaatatgcaaggcatattctgtgtatgatgaagagattggttactgccagggccagtccttcctcgcagctgtactgcttctccacatgcccgaagaacaggcattcagtgttctggtcaagatcatgtttgactatggtctcagggaacttttcaaacaaaattttgaagatcttcattgcaagttctaccagttggagcgccttatgcaggaatacattcctgacctgtacaaccacttcctggatatcagccttgaagcacacatgtacgcctcccagtggttccttacacttttcactgcaaaattccctctctacatggtcttccatatcatcgacctgctcttatgtgagggaataagtgtcatctttaatgtcgcccttggattactaaagacttccaaggatgacttgctgttgacagactttgagggtgccttgaagttcttcagggttcagctccctaaaagataccgctcagaagaaaatgcaaagaggctcatggagcttgcctgtaacacaaagaatcctgctgtggctgtggagcctctgaaccatgtatctgtggaagccgacatttcaggcatgaaatgagtataagaaaagaaaacaggagagccaagcagtggtggtgcaagccttttaatctcagcacttgggaggcagaagcggatggatttctaagttccagaacagccagggctacaaagagaaaccctgtcttggaaaaaaaaaaagaagatgatcagcatctccataccaatgcagtcttaaccatttgctgttgaaaaaaaccctttgccttgcaggaggtacttactcatgagctgagagcaacactagcttgtgcttcattctctatccagatcatttgtgtggttatccagtagtagaattttaagtgttaggtgggtagtgtcctcaaagcctccccccattatttcctctcagactcttaaacataatgcttcacataatgaaatgaatcttcatggtgacctgtagggtctgtttagtgatgcctaaaccaaaggtgtcagtaaatgatggagttgagattagaactcagatctggttctagaaagaagagtggaaactttctctctgaacactgtacccaaagttacactacctctaaggctagtaagactagtgttttgttcattaattcatacattttagaactagatttctgtgaggaagtatgtgtatttctagtgcctcttttttccagtgagccccctccaatgctgctggctagtgcacaggcagcagcgcacttgcctcctcgtttaataaagctacattcctatgactgttcttggggccttggctactaattctttcttttgctgtagaaaaacattcaggtcagactcaaactcactcatgacaggaaagctttaaaggaatctgagtatgaactatttgaacaaataaaatgttaggagctttaatataaaggttaattacataagatattctagactgccagccttgggcctctatctgcttgtgtgatgcagggtagattagacagcagtattgtagatagatgataacttaaacagctgctgctcgtggctctgtggcctacctagcctgtctccatcaagtgaggtgttagagtgttcaggtcagcacagttatagatgttctgagggacgaaaaatgtgttcagtaacaatcatgttacagagatggcaggaaatgagtcacccagacatttcttgttgtgttgccggtaaacactggctatttatacatgtcacaactgatagtaaaatgaggtgataaccccaaccatcttcaaaaattgtttgaggcataaagtaggaatagaggcatctcactgtctagagagagatggtaagtcaaaagacaacactgccctaagcgttctgtagctagaaggtggaccatagtccaatttcttgagttgtcttcatcaactctgccctgcatcaggatccctcctgcaccagacctcttatttgttccccacagcccacctgatcacccagacactaactaggcttcaatctgaccatgtagctctaacagtcaacctcctacctttaccaatccctctgtttcccgcacacacacccaccctccccatacagcagcataccttttatctctgtaaaacattgaaggcattctggaaacctgctccttttccagaggccaggctaactcatatatttctgtgtaaatggactttatttatatagtttgatgtatgcagtgccttttcagaggactgctccctgctctgtttcctaattcagatagtgtcttagttaggattttacttctattgctatgaacagacaccacgaccaaggcaagtcttataaaggacaacatttaatttggggctggcttacaggttcagaggttcagtccattatcatctagtcattaccatctaggcaggcatgctgcaggcagagctgagagttctacatctttatctgaagtctgctagtggaagattggctcccaggcaactaggacaagggtattgaagcacacacccacaaggccacacctgccaacagtgccacttcctgggccaagcatatacaaaccctttcagataggttgccaaataatgactgcaacagcaaggaataattacagtttattgaaaagaactccctatgtgctacagagccttctgagcactgtatatgatagttttctgtcagggtatcctcttaacacacagaagcactattagtatttcacagataagtaagttatcagccaagccaagactggagctatggaatattattcactgagctaagtaagcagggtgcacctagagaccaggtcagcagctaccctcattctctctccatctgcataggccttaataccaagaaccagcttcactagggcagatagcatgtatttatatttaagagtgcattattcagttcttgtgacagattaatgactaaaggagagaggtgtttaggactacattggaacttacaccaaaataccaagcttagggacattgagataactcagcaggtaaaggtgcttgccgccaaacctgacagcctgagtccgggccccagaattcacatggtagaagtaaagagctaactcctgagtctatcctctgacctacataagtgacacatggtgcatgtggaaatggcacacattgatatatgtctccatacacagaaagagtgtaactaaataaatggaaaataaaagagttagtattcagagtttgactgaagggatgagcgcagggctctacccctaagccctgtgctgaggaacctctcagtagtgctacttctcagagtcaagtgctaacatgaacttgttccacttaagttacaacccacacttagtccagaagtttggtttatttttcttgaaagaaaccttaaacagaacaagggttcaatttcagttttagtcttgctgagggtaacattacctctttgtgtgatgctataattttcaaagccttcttataggagttagctactagatctttctgagctctgaagcagaatacatagcccatcctctctcctgagtttaagtacaagaaaaaatgagtctggatatttgagtagagactatgtctcttttggcataagtattttcatgcttactttgtgacagaatttagtaaagaatagcgttctgtctttgcagaatttatgtatctaatgctttacaaaaaacatggttgatggcagactatgaaggaagacctaatcctgttcaagcattaactaggcactggtggtatggtggcaagcaaaacagacacagaacacaacataacagtaaggatgcagtaattaagaagctgtggacttgggaggttccatgaaggagttgagttggtgctttaaggacatagagaagagctggtctgatatgtgtgaactgccatcacaatcactgttcttgcttcaagggcttctgcccttcagttagcagggaccaactctgtttcctgggagctcagctgtgggggcagcctgaactagctggttctggtatgaagacatccaagctcctaaagttagcactagtgagagctggaaggaagcacatgtatcattgatggaggaaggcacagtgaggcaagagtttgtgggagagacaacaactgaggctgaaggatgggaagagactaagctggtagagagattggaattttagaactggaaactctagggaaggtgaggaggctttgtctgcatctagttctagatgggacaccttggtgatagactgagtagatcgcatcatcattagacaagaaacgactatcttaacccaaaataattctttttttttttttttttttttttttgacatggtttccctgtgtagctctggctgtactggtactcactctgtagaccaggctggcctctaactcagaaatttgcctgcctctgccttccaagtgctgagattaaaggcatgcaccaccactggctggctaacccaaaataattcttatagtacttttaaattataaaaataaataataaaggtaattcactcctatgcataaaatactgaagagcaaaacgtagtgtgcatgaggtggacccagcattcaccacactcactggacatcaagggtgctgagtcaggccagctttaatcaaagataataaaatataggacttattttgaaattaacttttcaaagttttagttaagaagaaagtattaattctttcttggccttgaatgagagtgaaacattgaagtatcctgaaggtctgtgaagatgtacaagagatggtgtctggtcttcttttagaaggtgctcgaggagacttgtctttactgcctgccctcacttctcttttgcccagactgcaaagagtgggtggaagagtatgctgcccaaaagcctcagctacgttatttcatcactttctaatagagctggtacataagttcactgatcacacagatgtttgtgtacgtgtggtttctggtttgtgtgtatgtttgtttgtggtgagtgacttaggagaacagtgcagagatatgtggtagagacaccactcactctccagcttgtggactcctatgtttaatgggcatctttgtggagactgtagccagagctaaaggttgtacctggccagtggcttaaggatagcaatgccaggattccagaaacaaagctccagttcagacacatctgcttacaacccatacagaaggccagagccagtgataaaggacccaccaggatgcttgagctacatcagaggatgaccggaaagatgcacaagcactactactgccatgttgcagacatacatccagctcacccattctgcttagatttatctgtacttacctggacctgtggttggaaaatgagtaatttaatgttgaaaattgatggtttgagaacaaataagcactaaggtttataatcattttctaaactgaacatgtctgctttatcaagctgttatagctcatagtttttaaatttagtttttgaaacagagaatgagttagctgttcaaaaggagttaaacaaaggagagatgcatcctgaagattcacttttttaaaaaaaaaaatttatcttacattccaaatgttgctccccttccaggtcccccctcccagaggttttcaccccattccccctcccctttgcctctgaaagggtactccctcatccacctacctcccccccccccacctccctcctccagcatccctttcctgaggctctacaggaccaggtacatcctctctcactgaggcaagacaaggcagtcctctgctatacatgtgctggggggcacaaaccagctcatgtatgctctttgtgttggtggcttagtctctgggacttcccaggagtctgggtgtctagatactgtgtgtcttcctatgaggttgccattcccttccgtttctacaatccttctcctaactcttccagaggggaaaggttcactcataattgtggttagaattgctgcaaaagaagtacatgccagtacagagggaactcctgacaggcatgagaagaaagccgaaagggaaagaatgaagattctgcaggagaaagagaagtggttagtcctgatggagcatgaaaatctagagaagtaggatcactgagagagtgagtggaaaggaagcacagtggcttcaggaaggtagaaggtttcaccttgtggcttacaagaagaggaggcttgagaacagacagtggcattgtgaaatctgtttctaatggcaaagagaattgtgcctgttggaggcaacacagaagagggtaatgcagtggaaagaggcctagggagttttagaactttggtggacttgggctttgaatggaatccagtaaccaggccttcaggccccgattttacaattactgcttttcttccccctactctctttcctctttctttttccttttctttcttcttttttcttccttctttttccctttttcttcctcctcctctgttttgttttcaagacagggttttcctggctggcctctgaggtcactgcctctgcctccaaagagctggaactaccaccaactggcactacaatctcttcttgacaactttactcataaaacagaacctctagatccctcagatgatgactgagactggggatgcattttgtgtttagcaacactgctggtatgtcctatagaaaatggtggcattattgctactactaggacaacaacaataatgacaactaatactactaggggcaagtacagccacgaattcatgtgagcaaaggtgttctgtagaacactgttgtgagaatcttgattcctttaaaaaacacaaacacacacacacacacaaatataagaatttggttttgttttaatctcaggtatgggatgaggggctgcttcatatggtccatagcagtttctccctttccctttctccctttccctttccctttcctctctatccttttgtccctcctatctagtgttagggagttgaaaaggtgggagaatggtagaagacaaaagaatcaaagtagcaaaagacaagtggcacctaatgtggcagaatgggaaatttgatttcaaatgccatagaggaaattgcaggggacaaaggaatggatatttttttcaggagtccagcaaaaaaatttattgtgactgttactgctgggatatcctctggtttgctcgcaggcgtgtactttctgggttttttgtttgtttgttttgtttttgcttttttttcttctcctttctgtagtctctttcaaaggagattgagagaatgtctgtgcaactggaaaaattgcaggtgaaaatggaggggcctgagaaacaaacataaaggttgaaatatagcaacaaaaggattcactcagctctcatttctgaaagggttgaagaattggttgtgcaactgaaaaatcttgtgggtggaaatggaagctctggggtggtgaggagcactggaaaacggagtgcaaaaaggctctgtaccagagactgaacaagaaaatgggagtttcctgcaggatgaagagagggaaagaaagtgagctgagggcagttgggtcatagaaaaactgaaaaggtggaggacaatctgataaaaacagccatgccaccacagtgggaagaggagtgacccaaaattatgagatcaccatcaacttcctcagtagacatacagctagcatatgcttgctatggtgtgaaacaaggttatgacaagataggatggcttactatagaaatgaaggtggtttaaagaggctctagtattatatgggatgcatttgccttaagtgaaacaaattctaaataactgggttactcaaaatagaattatttcccaataatggaagggattggtgacagctgtactagagaccagtctacaaattgcaatggttaacatgctagagggaagaagctgtgaatattgaacagtgaaatcgagtgaagggaaggaatatagtaaaggatcagttgctgggagaagggcagtacaaaaaaaaaaaa

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