2025-09-13 20:09:04, GGRNA.v2 : RefSeq release 231 (Jul, 2025)
LOCUS NR_130324 121 bp RNA linear ROD 18-OCT-2021 DEFINITION Mus musculus microRNA 669f (Mir669f), microRNA. ACCESSION NR_130324 VERSION NR_130324.1 KEYWORDS RefSeq. SOURCE Mus musculus (house mouse) ORGANISM Mus musculus Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus. REFERENCE 1 (bases 1 to 121) AUTHORS Ghosh T, Aprea J, Nardelli J, Engel H, Selinger C, Mombereau C, Lemonnier T, Moutkine I, Schwendimann L, Dori M, Irinopoulou T, Henrion-Caude A, Benecke AG, Arnold SJ, Gressens P, Calegari F and Groszer M. TITLE MicroRNAs establish robustness and adaptability of a critical gene network to regulate progenitor fate decisions during cortical neurogenesis JOURNAL Cell Rep 7 (6), 1779-1788 (2014) PUBMED 24931612 REFERENCE 2 (bases 1 to 121) AUTHORS Polikepahad S and Corry DB. TITLE Profiling of T helper cell-derived small RNAs reveals unique antisense transcripts and differential association of miRNAs with argonaute proteins 1 and 2 JOURNAL Nucleic Acids Res 41 (2), 1164-1177 (2013) PUBMED 23185045 REFERENCE 3 (bases 1 to 121) AUTHORS Zhu JY, Strehle M, Frohn A, Kremmer E, Hofig KP, Meister G and Adler H. TITLE Identification and analysis of expression of novel microRNAs of murine gammaherpesvirus 68 JOURNAL J Virol 84 (19), 10266-10275 (2010) PUBMED 20668074 REFERENCE 4 (bases 1 to 121) AUTHORS Pogribny IP, Starlard-Davenport A, Tryndyak VP, Han T, Ross SA, Rusyn I and Beland FA. TITLE Difference in expression of hepatic microRNAs miR-29c, miR-34a, miR-155, and miR-200b is associated with strain-specific susceptibility to dietary nonalcoholic steatohepatitis in mice JOURNAL Lab Invest 90 (10), 1437-1446 (2010) PUBMED 20548288 REFERENCE 5 (bases 1 to 121) AUTHORS Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C and Bartel DP. TITLE Mammalian microRNAs: experimental evaluation of novel and previously annotated genes JOURNAL Genes Dev 24 (10), 992-1009 (2010) PUBMED 20413612 REFERENCE 6 (bases 1 to 121) AUTHORS Calabrese JM, Seila AC, Yeo GW and Sharp PA. TITLE RNA sequence analysis defines Dicer's role in mouse embryonic stem cells JOURNAL Proc Natl Acad Sci U S A 104 (46), 18097-18102 (2007) PUBMED 17989215 REMARK Erratum:[Proc Natl Acad Sci U S A. 2007 Dec 26;104(52):21021] REFERENCE 7 (bases 1 to 121) AUTHORS Griffiths-Jones S, Grocock RJ, van Dongen S, Bateman A and Enright AJ. TITLE miRBase: microRNA sequences, targets and gene nomenclature JOURNAL Nucleic Acids Res 34 (Database issue), D140-D144 (2006) PUBMED 16381832 COMMENT PROVISIONAL REFSEQ: This record is based on preliminary annotation provided by NCBI staff in collaboration with miRBase. The reference sequence was derived from AL772216.15. Summary: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]. Sequence Note: This record represents a predicted microRNA stem-loop as defined by miRBase. Some sequence at the 5' and 3' ends may not be included in the intermediate precursor miRNA produced by Drosha cleavage. ##Evidence-Data-START## Transcript is intronless :: SRR7652917.943261.1 [ECO:0000345] ##Evidence-Data-END## PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-121 AL772216.15 43263-43383 FEATURES Location/Qualifiers source 1..121 /organism="Mus musculus" /mol_type="transcribed RNA" /strain="C57BL/6" /db_xref="taxon:10090" /chromosome="2" /map="2 8.22 cM" gene 1..121 /gene="Mir669f" /gene_synonym="Mirn669f; mmu-mir-669f" /note="microRNA 669f" /db_xref="GeneID:100316667" /db_xref="MGI:MGI:3783384" /db_xref="miRBase:MI0006287" precursor_RNA 1..121 /gene="Mir669f" /gene_synonym="Mirn669f; mmu-mir-669f" /product="microRNA 669f" /db_xref="GeneID:100316667" /db_xref="MGI:MGI:3783384" /db_xref="miRBase:MI0006287" exon 1..121 /gene="Mir669f" /gene_synonym="Mirn669f; mmu-mir-669f" /inference="alignment:Splign:2.1.0" ncRNA 20..43 /ncRNA_class="miRNA" /gene="Mir669f" /gene_synonym="Mirn669f; mmu-mir-669f" /product="mmu-miR-669f-5p" /db_xref="miRBase:MIMAT0017327" /db_xref="GeneID:100316667" /db_xref="MGI:MGI:3783384" /db_xref="miRBase:MI0006287" ncRNA 57..79 /ncRNA_class="miRNA" /gene="Mir669f" /gene_synonym="Mirn669f; mmu-mir-669f" /product="mmu-miR-669f-3p" /db_xref="miRBase:MIMAT0005839" /db_xref="GeneID:100316667" /db_xref="MGI:MGI:3783384" /db_xref="miRBase:MI0006287" ORIGIN
tgtatgtgcctgtgtgtatagttgtgtgtgcatgtgcatgtgtgtatatgaatatacatatacatacacacacacgtataaacgcaagcacaaacacacacagaggaatggcactcgttga
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Creative Commons Attribution 4.0 International License (CC BY 4.0).
If you use GGRNA in your work, please cite:
Naito Y, Bono H. (2012)
GGRNA: an ultrafast, transcript-oriented search engine for genes and transcripts.
Nucleic Acids Res., 40, W592-W596.
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