LOCUS       NR_015348               1560 bp    RNA     linear   ROD 19-NOV-2024
DEFINITION  Mus musculus homeobox A11, opposite strand (Hoxa11os), long
            non-coding RNA.
ACCESSION   NR_015348
VERSION     NR_015348.2
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1560)
  AUTHORS   Shmuel-Galia,L., Humphries,F., Vierbuchen,T., Jiang,Z., Santos,N.,
            Johnson,J., Shklyar,B., Joannas,L., Mustone,N., Sherman,S.,
            Ward,D., Houghton,J., Baer,C.E., O'Hara,A., Henao-Mejia,J.,
            Hoebe,K. and Fitzgerald,K.A.
  TITLE     The lncRNA HOXA11os regulates mitochondrial function in myeloid
            cells to maintain intestinal homeostasis
  JOURNAL   Cell Metab 35 (8), 1441-1456 (2023)
   PUBMED   37494932
  REMARK    GeneRIF: The lncRNA HOXA11os regulates mitochondrial function in
            myeloid cells to maintain intestinal homeostasis.
REFERENCE   2  (bases 1 to 1560)
  AUTHORS   Gao,F., Wang,X.C., Luo,Z.D., Hu,G.Q., Ma,M.Q., Liang,Y., Xu,B.L.
            and Lin,X.H.
  TITLE     LncRNA HOXA11-AS promotes vascular endothelial cell injury in
            atherosclerosis by regulating the miR-515-5p/ROCK1 axis
  JOURNAL   ESC Heart Fail 9 (4), 2259-2271 (2022)
   PUBMED   35578440
  REMARK    GeneRIF: LncRNA HOXA11-AS promotes vascular endothelial cell injury
            in atherosclerosis by regulating the miR-515-5p/ROCK1 axis.
REFERENCE   3  (bases 1 to 1560)
  AUTHORS   Cao,H., Han,X., Jia,Y. and Zhang,B.
  TITLE     Inhibition of long non-coding RNA HOXA11-AS against
            neuroinflammation in Parkinson's disease model via targeting
            miR-124-3p mediated FSTL1/NF-kappaB axis
  JOURNAL   Aging (Albany NY) 13 (8), 11455-11469 (2021)
   PUBMED   33839699
  REMARK    GeneRIF: Inhibition of long non-coding RNA HOXA11-AS against
            neuroinflammation in Parkinson's disease model via targeting
            miR-124-3p mediated FSTL1/NF-kappaB axis.
REFERENCE   4  (bases 1 to 1560)
  AUTHORS   Kherdjemil,Y., Lalonde,R.L., Sheth,R., Dumouchel,A., de Martino,G.,
            Pineault,K.M., Wellik,D.M., Stadler,H.S., Akimenko,M.A. and
            Kmita,M.
  TITLE     Evolution of Hoxa11 regulation in vertebrates is linked to the
            pentadactyl state
  JOURNAL   Nature 539 (7627), 89-92 (2016)
   PUBMED   27706137
REFERENCE   5  (bases 1 to 1560)
  AUTHORS   Lai,K.M., Gong,G., Atanasio,A., Rojas,J., Quispe,J., Posca,J.,
            White,D., Huang,M., Fedorova,D., Grant,C., Miloscio,L.,
            Droguett,G., Poueymirou,W.T., Auerbach,W., Yancopoulos,G.D.,
            Frendewey,D., Rinn,J. and Valenzuela,D.M.
  TITLE     Diverse Phenotypes and Specific Transcription Patterns in Twenty
            Mouse Lines with Ablated LincRNAs
  JOURNAL   PLoS One 10 (4), e0125522 (2015)
   PUBMED   25909911
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 1560)
  AUTHORS   Schwab,K., Hartman,H.A., Liang,H.C., Aronow,B.J., Patterson,L.T.
            and Potter,S.S.
  TITLE     Comprehensive microarray analysis of Hoxa11/Hoxd11 mutant kidney
            development
  JOURNAL   Dev Biol 293 (2), 540-554 (2006)
   PUBMED   16581055
REFERENCE   7  (bases 1 to 1560)
  AUTHORS   Chau,Y.M., Pando,S. and Taylor,H.S.
  TITLE     HOXA11 silencing and endogenous HOXA11 antisense ribonucleic acid
            in the uterine endometrium
  JOURNAL   J Clin Endocrinol Metab 87 (6), 2674-2680 (2002)
   PUBMED   12050232
REFERENCE   8  (bases 1 to 1560)
  AUTHORS   Potter,S.S. and Branford,W.W.
  TITLE     Evolutionary conservation and tissue-specific processing of Hoxa 11
            antisense transcripts
  JOURNAL   Mamm Genome 9 (10), 799-806 (1998)
   PUBMED   9745033
REFERENCE   9  (bases 1 to 1560)
  AUTHORS   Peichel,C.L., Prabhakaran,B. and Vogt,T.F.
  TITLE     The mouse Ulnaless mutation deregulates posterior HoxD gene
            expression and alters appendicular patterning
  JOURNAL   Development 124 (18), 3481-3492 (1997)
   PUBMED   9342041
REFERENCE   10 (bases 1 to 1560)
  AUTHORS   Hsieh-Li,H.M., Witte,D.P., Weinstein,M., Branford,W., Li,H.,
            Small,K. and Potter,S.S.
  TITLE     Hoxa 11 structure, extensive antisense transcription, and function
            in male and female fertility
  JOURNAL   Development 121 (5), 1373-1385 (1995)
   PUBMED   7789268
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC015583.34.
            
            On Jul 20, 2023 this sequence version replaced NR_015348.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR12282455.35560915.1 [ECO:0000332]
            RNAseq introns              :: partial sample support SAMN00849389,
                                           SAMN01164133 [ECO:0000350]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-624               AC015583.34        67710-68333         c
            625-707             AC015583.34        67509-67591         c
            708-853             AC015583.34        66558-66703         c
            854-1560            AC015583.34        63576-64282         c
FEATURES             Location/Qualifiers
     source          1..1560
                     /organism="Mus musculus"
                     /mol_type="transcribed RNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="6"
                     /map="6 25.4 cM"
     gene            1..1560
                     /gene="Hoxa11os"
                     /gene_synonym="Hoxa11as; Hoxa11s"
                     /note="homeobox A11, opposite strand"
                     /db_xref="GeneID:15397"
                     /db_xref="MGI:MGI:107208"
     ncRNA           1..1560
                     /ncRNA_class="lncRNA"
                     /gene="Hoxa11os"
                     /gene_synonym="Hoxa11as; Hoxa11s"
                     /product="homeobox A11, opposite strand"
                     /db_xref="GeneID:15397"
                     /db_xref="MGI:MGI:107208"
     exon            1..624
                     /gene="Hoxa11os"
                     /gene_synonym="Hoxa11as; Hoxa11s"
                     /inference="alignment:Splign:2.1.0"
     exon            625..707
                     /gene="Hoxa11os"
                     /gene_synonym="Hoxa11as; Hoxa11s"
                     /inference="alignment:Splign:2.1.0"
     exon            708..853
                     /gene="Hoxa11os"
                     /gene_synonym="Hoxa11as; Hoxa11s"
                     /inference="alignment:Splign:2.1.0"
     exon            854..1560
                     /gene="Hoxa11os"
                     /gene_synonym="Hoxa11as; Hoxa11s"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      

agtgtggccggaagacgactcggggctgctgctgctctcgggtcgccgccgtcgctccttctcctccgccgccgcctcctgacagccgccgccaccgccgccgtccgaacttgaagttgccggcgcgcccgtggccgccgccgccaccgccgcagcggaggtcgcagctgctgcttggggccccttctcggcgttcttgtccccggggtagtcggaggaagcgaggttttccggggtgccgtaagccgtctcgaaaaactggtcgaaagcctgtggcagaacgccgttcctgcccaccgtgctatagaaattggacgagacggcgggggtggggtggtggtagacgttggccgagctcttggccagcacgtcgccaggcacgccggccgcgctgggcgcctgcagacagtctctgtgcacgagctcctccgcggagtagcagtgggccagattgccgcgggggtgccatttagtggcgggctcaatggcgtactctctgaaggtcacttcgcgcacgggttggacctggggcaggttggaggagtaggagtatgtcattgggcgcgaagacggggtctggggcaaaaaagaagggaggctggagaaatctggacccgagacgtactgcctctttgaagcggatccgtgaagtagaaatttggagacgtaagctgacgtggaaatctatccccatccttagcagggaggggttcggagtgactcctcagagccagaggcacttctgctcaccggtccgcaagctgcctggtctgctgaagctgacgaatcgggaaaccatgcaattgaggcgaaccttgggctgttttagaggcgctgaggagccttctcctgggaggcccaaggttgatttcagcccaccaggatctggggaagacccaactagggataagagcacaccaaaaggccaagtccgagttccatttctagaagaggcggcttccggcaaggctatgacattggccctggacattggtttcccaggagctgctttttctcaagaactccacagcacggggctgtctccagaaaacgctcttcaacgtttatttcttttaatcgtcgcccggagccctaaggcggctaatgcaagaggccaaaaatgtttggaggaagaaaaacaaaggcaggaagtggccgcggcctgacggtgcgtgtgtgtctgtaaagaagggagggagccggttcaacctcccctcgttttcccgaacttcaaggtctaggcagacccccttagggccttgccgaggctcgcccccacacccccagcggcgcagcatttggaggtggccaacgatttaagcctcggtcgggctgaaaggagatttgatcggcagaacaaaccaacccttttcggaggtttcttttgatttggtcctaaagggtatatgctagtgtccacagcggctggggtggctgctgttttcctcccgccgggctaaaagtaccaagaagggagggagggagagagattcaggcaccttgcgctggctgcactctccttctgagatagaataccagaataaagtgtattcaggtgcc

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