LOCUS       NM_001419337            3663 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus NudC domain containing 3 (Nudcd3), transcript variant
            3, mRNA.
ACCESSION   NM_001419337
VERSION     NM_001419337.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3663)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3663)
  AUTHORS   Yang,J., Xu,J., Zhang,L., Li,Y. and Chen,M.
  TITLE     Identifying key m6A-methylated lncRNAs and genes associated with
            neural tube defects via integrative MeRIP and RNA sequencing
            analyses
  JOURNAL   Front Genet 13, 974357 (2022)
   PUBMED   36482889
  REMARK    Erratum:[Front Genet. 2023 Jul 10;14:1198975. PMID: 37496715]
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 3663)
  AUTHORS   Okazaki,N., Kikuno,R., Ohara,R., Inamoto,S., Koseki,H., Hiraoka,S.,
            Saga,Y., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: III. the complete nucleotide sequences of 500 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 10 (4), 167-180 (2003)
   PUBMED   14621295
REFERENCE   4  (bases 1 to 3663)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL607152.21 and AL611926.12.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR17784649.138890.1,
                                           SRR13422598.1319734.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-248               AL607152.21        7158-7405           c
            249-571             AL611926.12        134761-135083       c
            572-704             AL611926.12        92102-92234         c
            705-848             AL611926.12        67025-67168         c
            849-3663            AL611926.12        58315-61129         c
FEATURES             Location/Qualifiers
     source          1..3663
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 3.91 cM"
     gene            1..3663
                     /gene="Nudcd3"
                     /gene_synonym="mKIAA1068"
                     /note="NudC domain containing 3"
                     /db_xref="GeneID:209586"
                     /db_xref="MGI:MGI:2144158"
     exon            1..248
                     /gene="Nudcd3"
                     /gene_synonym="mKIAA1068"
                     /inference="alignment:Splign:2.1.0"
     CDS             57..956
                     /gene="Nudcd3"
                     /gene_synonym="mKIAA1068"
                     /note="isoform 3 is encoded by transcript variant 3; nudC
                     domain-containing protein 3"
                     /codon_start=1
                     /product="nudC domain-containing protein 3 isoform 3"
                     /protein_id="NP_001406266.1"
                     /db_xref="GeneID:209586"
                     /db_xref="MGI:MGI:2144158"
                     /translation="

MEPGAAELYDQALLGILQHVGNVQDFLRVLFGFLYRKTDFYRLLRHPSDRMGFPPGAAQALVLQVFKTFDHMARQDDEKRKKELEEKIRKKEEEAKALPAAETEKVAVPVPVQEVEIDAAADLSGPQEVEKEEPPGSQDPEHTVTHGLEKAEAPGTVSSAAEGPKDPPVLPRIQEQFQKNPDSYNGAIRENYIWSQDYTDLEVRVPVPKHVMKGKQVSVALSSGTIRVAMVEENGERVLMEGKLTHKINTESSLWSLEPGRCVLVPSWKERPTTFPLAQTQSHGQLRGVKPSSLGTVLP"

     misc_feature    81..257
                     /gene="Nudcd3"
                     /gene_synonym="mKIAA1068"
                     /note="N-terminal conserved domain of Nudc; Region:
                     Nudc_N; pfam14050"
                     /db_xref="CDD:464073"
     misc_feature    414..485
                     /gene="Nudcd3"
                     /gene_synonym="mKIAA1068"
                     /note="propagated from UniProtKB/Swiss-Prot (Q8R1N4.3);
                     Region: Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite"
     misc_feature    612..>851
                     /gene="Nudcd3"
                     /gene_synonym="mKIAA1068"
                     /note="The alpha-crystallin-Hsps_p23-like superfamily
                     includes the alpha-crystallin domain (ACD) of
                     alpha-crystallin-type small heat shock proteins (sHsps)
                     and a similar domain found in p23-like proteins. sHsps are
                     small stress induced proteins with monomeric...; Region:
                     alpha-crystallin domain (ACD) found in
                     alpha-crystallin-type small heat shock proteins, and a
                     similar domain found in p23 (a cochaperone for Hsp90) and
                     in other p23-like proteins.; cl00175"
                     /db_xref="CDD:469641"
     exon            249..571
                     /gene="Nudcd3"
                     /gene_synonym="mKIAA1068"
                     /inference="alignment:Splign:2.1.0"
     exon            572..704
                     /gene="Nudcd3"
                     /gene_synonym="mKIAA1068"
                     /inference="alignment:Splign:2.1.0"
     exon            705..848
                     /gene="Nudcd3"
                     /gene_synonym="mKIAA1068"
                     /inference="alignment:Splign:2.1.0"
     exon            849..3663
                     /gene="Nudcd3"
                     /gene_synonym="mKIAA1068"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3640..3645
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Nudcd3"
                     /gene_synonym="mKIAA1068"
                     /note="hexamer: AATAAA"
     polyA_site      3663
                     /gene="Nudcd3"
                     /gene_synonym="mKIAA1068"
                     /note="major polyA site"
ORIGIN      

aatcagccggtgtgaggcggtgcccactgtgttcgcgtccctcgggcagcagagccatggagcccggggctgctgagctttatgaccaggccctgttgggcatcctgcagcacgtgggcaatgtccaggactttctgcgcgtgctcttcggctttctctaccgcaagaccgacttctaccgcctgctgcgccacccttcggaccgcatgggcttcccgcccggggccgcacaggccctggtgctgcaggtctttaaaacatttgatcacatggcccgccaggatgatgagaaaaggaagaaagaactagaagagaaaataagaaaaaaggaggaagaggccaaggccttgccagctgctgaaactgagaaggtagcggtgccggtcccagtgcaggaggtagagatcgatgctgctgcagacttgagtgggcctcaggaagtagagaaggaggagcccccaggctcccaggaccccgagcacacagtgacccatggcctggagaaggcggaagctccaggaacagttagcagtgctgctgaaggccctaaggaccctcctgtgctccccaggattcaggagcagttccagaaaaatcctgacagttacaacggtgccatccgtgagaactacatctggtcgcaagactacaccgacctggaggtcagggtgcccgtgcccaagcatgtgatgaaggggaagcaggtctctgtggcccttagcagtggcaccatccgagtggccatggtggaagagaatggagagcgtgtcctcatggaggggaagctcactcacaagatcaacaccgagagctccctctggagccttgagcccggcaggtgtgttttggtgccttcctggaaggaacgtcccacaacattcccgttggcccaaactcaatcccacgggcagctgcgaggagtaaagccatcctcactgggcacagtgcttccctgaatagaaatgaggttccgttactaaggaaggaaagggatagaaatgctggtgagtcatcggcacagatcgggggatgctgaggtaagtttattcacaccgagggtgaagtttttctgcgaggacattttgggagcactgttcagtcagtgacaatctggggtccctctgggaaattattgtgttctgggaccaggcaggtaaaggaggacctggaaaatgagagtgcatccaggaaatggtgaggtcacagtgaccttggaaagggccacctcattttgccccaacggttcagagtgactttctaagccactgagaaaggtggtggccaggaggcagcaagcagtttccttgaacagaaggtgctgtctttagcagtgcccatgccctgtcagtaaggagaggtcagtgggagatgggacctcacagggtcctaagagcttgatgcttatgtgttaatgtgacagtgtgggaaggcctggaatgagagggaatgttcttgcaagatacctgcaggtgggccacatacacacctgggttcctcaggagacactagacagggtccttagcgaagtagagaggaccagggaagcaggccaggctgctacttgagaagacttacttagtcttagaaagtaagtcagggtacagggccaacacagtggtccttactcttaaatgattcagaaaaaagcattatttattatgttttatgcaaacacatacagagtaggacagttgctaaatgcctgtgtggctctctgtactttcagcaatgtgtaaatttgaagttttttgcaaataagaaatgagtagtgttacaaacatacaaggaaactcagcatcactagggaaataaagtcaaaattacagtgagatgccttgtatacctgtgagagtggctgccaagaagcccatagtgctcaatttggaggagctgtgggaccctgaacgcctcactgctactatgagtgccaggtggtggacatagccagtgtgcccacattgcagccctaatgacctgctctgtgctcccaagaggaggaaacgcacacatctttacaacagcttcctacccaaccaccaaaccctaggaacacctacacggccatggacagatagtgatcacctacatcatgggatagtcttgccaagcatcatagcccacaggatccagaaaggaagcgtgtatacaagcccacaagctgtggtgttcaggggaagacatcctggacctggacaagctggatggcaagatgagcaatgcaaaatgaagtggagggaaggcctgggtgtgggtgggttgtagtggaggctggaggagactaaattgcaacagggtgagttttactgtgtgcaaactacacctcctcaagtctgacttgttacaaagtaacaaaatgttaaaacaaaaacagctaatttaagcaaaccatgggactacttttgccagggtgtggtctttagccaggaacccttgaaatctcttccatgagcatttttcctctgttctcacacaactcagattctgtcttcagtatcaagaataccctaccctaccctcggagacctgagtgtattctaaccactttaagtagtttatttggaagattaagtgcccaaagtgtcttacctgagttccctaggggtattactccaaggaagtcagtgatgctcagaagaacgtgtcagctaagacttctgggacatgaaggtatttaaaaagtcaaggctaggtcctggctgtgagggtaaggagccagacagcacagcacatgaaatgcttcaaggaagctttgtggcaaacaaaggaggccaggccaaggtaggggaagatactcatgagccgtcactaacactgcagcctcacttaacccttgactgcccactcagaatagtcacagaagctttggaaatgacagaacctttggtatggtctcctgccccagattcaagagcatcctgaaccttagggcagaggtcactgagaaaaatactgaaccatgtatacttgtgtatagccaggcaaaagaataacaagctacggcaccctcgaaaatggctatgacaaaaacaaaacaacaacaacaaaactaaatatccatgagggagtagagggctggatcctttccttgtgcagtaccaggatgtggaaggagtccagctccagtgggaaacgatttggtgctttcttgagacctaaagtaccatgtgagccagcaattccattcctaggtaaataccaaaggaagggaaaacagaaacccttgcacatagcagcattattcacatagccaaaagggggagaatggataacaggctgtggttaattcatccagtggaatgctcctcagcatggagaggaatgaagttctgatatgtgccacaacactgatgaccttcaaaaaccttataataagtgaaaggagccaacacagagcaatgtaaggtttcacttgtgtgaaatccaatgagacaaaagcatcagtaattgtgccggaggtgtcagggaagatatttaggagattttattatggtaagatgaagagtaattacatctggctatagggcttctttttggagtgatgtttcaggatacatatgtggttagttgcataccatcatgggtgtaccaattgccattgaactgttgacttttgaaaaaaaaagtgttatgtaatttcacaataaaaaattgttttaaaaataa

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