LOCUS       NM_001360720            1332 bp    mRNA    linear   ROD 05-JUN-2024
DEFINITION  Mus musculus STAM binding protein like 1 (Stambpl1), transcript
            variant 6, mRNA.
ACCESSION   NM_001360720 XM_006527457
VERSION     NM_001360720.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1332)
  AUTHORS   Lavorgna,A. and Harhaj,E.W.
  TITLE     An RNA interference screen identifies the Deubiquitinase STAMBPL1
            as a critical regulator of human T-cell leukemia virus type 1 tax
            nuclear export and NF-kappaB activation
  JOURNAL   J Virol 86 (6), 3357-3369 (2012)
   PUBMED   22258247
  REMARK    Erratum:[J Virol. 2012 May;86(9):5409]
REFERENCE   2  (bases 1 to 1332)
  AUTHORS   Kitajima,K., Matsumoto,K., Tahara,M., Takahashi,H., Nakamura,T. and
            Nakamura,T.
  TITLE     A newly identified AMSH-family protein is specifically expressed in
            haploid stages of testicular germ cells
  JOURNAL   Biochem Biophys Res Commun 309 (1), 135-142 (2003)
   PUBMED   12943674
  REMARK    GeneRIF: AMSH-FP is specifically expressed in haploid stages of
            testicular germ cells and has a functional role in spermiogenesis
            [AMSH-FP]
REFERENCE   3  (bases 1 to 1332)
  AUTHORS   Takahashi,H., Koshimizu,U. and Nakamura,T.
  TITLE     A novel transcript encoding truncated LIM kinase 2 is specifically
            expressed in male germ cells undergoing meiosis
  JOURNAL   Biochem Biophys Res Commun 249 (1), 138-145 (1998)
   PUBMED   9705845
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC102285.7 and AK007087.1.
            
            On Feb 10, 2018 this sequence version replaced XM_006527457.3.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AB066212.1, AK007087.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849384 [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-17                AC102285.7         61415-61431
            18-301              AK007087.1         2-285
            302-418             AC102285.7         62871-62987
            419-1230            AK007087.1         403-1214
            1231-1332           AC102285.7         69022-69123
FEATURES             Location/Qualifiers
     source          1..1332
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="19"
                     /map="19 29.35 cM"
     gene            1..1332
                     /gene="Stambpl1"
                     /gene_synonym="1700095N21Rik; 8230401J17Rik; ALMalpha;
                     AMSH-FP"
                     /note="STAM binding protein like 1"
                     /db_xref="GeneID:76630"
                     /db_xref="MGI:MGI:1923880"
     exon            1..181
                     /gene="Stambpl1"
                     /gene_synonym="1700095N21Rik; 8230401J17Rik; ALMalpha;
                     AMSH-FP"
                     /inference="alignment:Splign:2.1.0"
     misc_feature    173..175
                     /gene="Stambpl1"
                     /gene_synonym="1700095N21Rik; 8230401J17Rik; ALMalpha;
                     AMSH-FP"
                     /note="upstream in-frame stop codon"
     exon            182..539
                     /gene="Stambpl1"
                     /gene_synonym="1700095N21Rik; 8230401J17Rik; ALMalpha;
                     AMSH-FP"
                     /inference="alignment:Splign:2.1.0"
     CDS             260..1072
                     /gene="Stambpl1"
                     /gene_synonym="1700095N21Rik; 8230401J17Rik; ALMalpha;
                     AMSH-FP"
                     /EC_number="3.1.2.15"
                     /note="isoform 2 is encoded by transcript variant 6;
                     AMSH-family protein; AMSH-like protease; AMSH-LP"
                     /codon_start=1
                     /product="AMSH-like protease isoform 2"
                     /protein_id="NP_001347649.1"
                     /db_xref="GeneID:76630"
                     /db_xref="MGI:MGI:1923880"
                     /translation="

MRQQQLESEQFLFFEDQLKKQELARGQIRGQDSPVLSEQTDGSALSCFSTHQSNSLRNAFADHPHKSDGSNFANYSPPVNRALKPAATLSAVQNLVVEGLRCVVLSRDLCHKFLLLADSNTVRGIETCGILCGKLTHNEFTITHVVVPKQSAGPDYCDVENVEELFNVQDQHGLLTLGWIHTHPTQTAFLSSVDLHTHCSYQLMLPEAIAIVCSPKHKDTGIFRLTNAGMLEVSTCKKKGFHPHTKDPKLFSICSHVLVKDIKTTVLDLR"

     misc_feature    557..1069
                     /gene="Stambpl1"
                     /gene_synonym="1700095N21Rik; 8230401J17Rik; ALMalpha;
                     AMSH-FP"
                     /note="Mov34/MPN/PAD-1 family; Region: MPN_AMSH_like;
                     cd08066"
                     /db_xref="CDD:163697"
     misc_feature    order(635..637,800..802,806..808,830..832,839..841)
                     /gene="Stambpl1"
                     /gene_synonym="1700095N21Rik; 8230401J17Rik; ALMalpha;
                     AMSH-FP"
                     /note="MPN+ (JAMM) motif [active]"
                     /db_xref="CDD:163697"
     misc_feature    order(641..649,722..736,743..748,755..757,764..766,
                     782..787,794..796,800..802,806..808,830..832,836..841,
                     845..850,857..862,866..871,980..982)
                     /gene="Stambpl1"
                     /gene_synonym="1700095N21Rik; 8230401J17Rik; ALMalpha;
                     AMSH-FP"
                     /note="Distal ubiquitin recognition interface [polypeptide
                     binding]; other site"
                     /db_xref="CDD:163697"
     misc_feature    order(722..724,806..808,815..820,824..826,830..835,
                     980..988)
                     /gene="Stambpl1"
                     /gene_synonym="1700095N21Rik; 8230401J17Rik; ALMalpha;
                     AMSH-FP"
                     /note="Proximal ubiquitin recognition interface [active]"
                     /db_xref="CDD:163697"
     misc_feature    order(800..802,806..808,839..841)
                     /gene="Stambpl1"
                     /gene_synonym="1700095N21Rik; 8230401J17Rik; ALMalpha;
                     AMSH-FP"
                     /note="Zinc-binding site [ion binding]; other site"
                     /db_xref="CDD:163697"
     exon            540..664
                     /gene="Stambpl1"
                     /gene_synonym="1700095N21Rik; 8230401J17Rik; ALMalpha;
                     AMSH-FP"
                     /inference="alignment:Splign:2.1.0"
     exon            665..802
                     /gene="Stambpl1"
                     /gene_synonym="1700095N21Rik; 8230401J17Rik; ALMalpha;
                     AMSH-FP"
                     /inference="alignment:Splign:2.1.0"
     exon            803..915
                     /gene="Stambpl1"
                     /gene_synonym="1700095N21Rik; 8230401J17Rik; ALMalpha;
                     AMSH-FP"
                     /inference="alignment:Splign:2.1.0"
     exon            916..1015
                     /gene="Stambpl1"
                     /gene_synonym="1700095N21Rik; 8230401J17Rik; ALMalpha;
                     AMSH-FP"
                     /inference="alignment:Splign:2.1.0"
     exon            1016..1332
                     /gene="Stambpl1"
                     /gene_synonym="1700095N21Rik; 8230401J17Rik; ALMalpha;
                     AMSH-FP"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1307..1312
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Stambpl1"
                     /gene_synonym="1700095N21Rik; 8230401J17Rik; ALMalpha;
                     AMSH-FP"
                     /note="hexamer: AATAAA"
     polyA_site      1327
                     /gene="Stambpl1"
                     /gene_synonym="1700095N21Rik; 8230401J17Rik; ALMalpha;
                     AMSH-FP"
                     /note="major polyA site"
ORIGIN      

accacgtcttgggctacagaatttaacatttgagtacacagcagcaccaaaccaggtcccaacggatttgctgctttgtctctttgctttgaaggttgctggctctaccacctcttacttcacatcgatctctctctacctccgcaaacagtctcagagcgggaagcctggctagcatgagaacaaatataaagccgaaattctcaaaaagttggaacatcagagactgatagaggcagagcgccagcggatagctcagatgcgccagcagcaactagagtctgaacagttcctgttttttgaagaccaactcaagaagcaggagttggctcgaggccagattcgaggtcaggactctccggtgttgtctgagcagactgacggaagtgcgctgtcctgcttttccacccaccagagcaactctctgaggaacgcatttgcagatcaccctcataaaagtgatggaagcaatttcgctaactactctcctcccgtgaacagggccctaaagccagcagccaccctgagtgctgttcagaatttggtggttgaagggctgaggtgtgtagttttatcaagagatctttgccataaatttctgctgctggctgactctaacacagtgagaggaatagagacctgtgggatcctctgtggaaaactgacacacaatgaattcaccattactcatgtggttgtgccaaagcagtctgctggcccagactattgcgatgtggagaacgtcgaagaattattcaatgttcaggatcaacatggtctcctcacactgggatggatccatacacaccccacgcaaacggcattcctgtccagtgtggatctccacactcactgctcctaccagcttatgttgccagaggccattgccattgtgtgttccccaaagcataaagacaccggcattttcaggctcaccaacgctggcatgcttgaggtttctacttgtaaaaagaagggcttccatcctcacaccaaggaccccaagctgttcagtatatgcagccatgtgttagtaaaggacataaaaacaactgtgttggatctgaggtgacatgccctaactgtaagaccatctgtggacgtgtgtgactgccgaatttcttatgatgttttcagaagtgactgatattttatatttatatattttagaccaaaactttgatatttattgttcttgcacattttgaagtttccttttttttttttttttgggttgctgcgtctcaaacgaggccacgtggtgttcagcctatacctattaatatacccaagtgatgccatcggaaataaattgtgctgcaaataacaagc

//