LOCUS       XM_054368195            7563 bp    mRNA    linear   PRI 26-AUG-2024
DEFINITION  PREDICTED: Homo sapiens formin binding protein 4 (FNBP4),
            transcript variant X3, mRNA.
ACCESSION   XM_054368195
VERSION     XM_054368195.1
DBLINK      BioProject: PRJNA807723
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_060935) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_009914755.1-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7563
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /isolate="CHM13"
                     /db_xref="taxon:9606"
                     /chromosome="11"
                     /sex="female"
                     /cell_line="CHM13htert"
                     /tissue_type="hydatidiform mole"
                     /note="haploid cell line"
     gene            1..7563
                     /gene="FNBP4"
                     /gene_synonym="FBP30"
                     /note="formin binding protein 4; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 2
                     mRNAs, 24 ESTs, 577 long SRA reads, and 89% coverage of
                     the annotated genomic feature by RNAseq alignments,
                     including 92 samples with support for all annotated
                     introns"
                     /db_xref="GeneID:23360"
                     /db_xref="HGNC:HGNC:19752"
                     /db_xref="MIM:615265"
     CDS             54..2108
                     /gene="FNBP4"
                     /gene_synonym="FBP30"
                     /codon_start=1
                     /product="formin-binding protein 4 isoform X3"
                     /protein_id="XP_054224170.1"
                     /db_xref="GeneID:23360"
                     /db_xref="HGNC:HGNC:19752"
                     /db_xref="MIM:615265"
                     /translation="

MGKKSRAVPGRRPILQLSPPGPRGSTPGRDPEPEPDTEPDSTAAVPSQPAPSAATTTTTAVTAAAASDDSPSEGKDEQEAVQEVPRVVQNPPKPVMTTRPTAVKATGGLCLLGAYADSDDDDNDVSEKLAQSKETNGNQSTDIDSTLANFLAEIDAITAPQPAAPVGASAPPPTPPRPEPKEAATSTLSSSTSNGTDSTQTSGWQYDTQCSLAGVGIEMGDWQEVWDENTGCYYYWNTQTNEVTWELPQYLATQVQGLQHYQPSSVPGAETSFVVNTDIYSKEKTISVSSSKSGPVIAKREVKKEVNEGIQALSNSEEEKKGVAASLLAPLLPEGIKEEEERWRRKVICKEEPVSEVKETSTTVEEATTIVKPQEIMLDNIEDPSQEDLCSVVQSGESEEEEEQDTLELELVLERKKAELRALEEGDGSVSGSSPRSDISQPASQDGMRRLMSKRGKWKMFVRATSPESTSRSSSKTGRDTPENGETAIGAENSEKIDENSDKEMEVEESPEKIKVQTTPKVEEEQDLKFQIGELANTLTSKFEFLGINRQSISNFHVLLLQTETRIADWREGALNGNYLKRKLQDAAEQLKQYEINATPKGWSCHWDRDHRRYFYVNEQSGESQWEFPDGEEEEEESQAQENRDETLAKQTLKDKTGTDSNSTESSETSTAVNELKRLDRSSG"

     misc_feature    714..797
                     /gene="FNBP4"
                     /gene_synonym="FBP30"
                     /note="WW domain; Region: WW; pfam00397"
                     /db_xref="CDD:459800"
     misc_feature    1851..1946
                     /gene="FNBP4"
                     /gene_synonym="FBP30"
                     /note="Two conserved tryptophans domain; also known as the
                     WWP or rsp5 domain; around 40 amino acids; functions as an
                     interaction module in a diverse set of signalling
                     proteins; binds specific proline-rich sequences but at low
                     affinities compared to other...; Region: WW; cd00201"
                     /db_xref="CDD:238122"
     misc_feature    order(1893..1895,1929..1931)
                     /gene="FNBP4"
                     /gene_synonym="FBP30"
                     /note="binding pocket [active]"
                     /db_xref="CDD:238122"
     polyA_site      7563
                     /gene="FNBP4"
                     /gene_synonym="FBP30"
                     /experiment="COORDINATES: polyA evidence [ECO:0006239]"
ORIGIN      

agtgcccgcccctctcggccgcccgacgctctctgctcgcgcttgggctcgcgatggggaagaagtcccgggcggtacccggccgtaggcccatcctgcaactctctccgccgggtcctcggggcagcacgccgggccgggacccggagccggaacccgacactgagccggactcaaccgcggcggtccccagccagcccgccccgtcggcggcgacgaccaccaccaccgcggtgactgccgccgcggcctcggacgactcgccttcagaaggcaaggatgaacaggaagcggtgcaggaggttcctagagttgttcagaatcctccaaaaccagtcatgaccactagacccacagctgttaaagcaacaggcggtctatgcttgcttggtgcttatgctgacagtgatgacgatgacaatgatgtttccgaaaaactagcacaatccaaagagacaaatggaaaccagtcaactgatattgatagtacattggccaacttcctagcggagatcgatgccataacagctcctcagcctgcagctcctgtaggagcttctgctccacctccaactccacctcgaccagagccaaaggaagcagcaacatctaccctttcttcttctacttcaaatggaacagactccacccaaacatctggttggcaatatgatactcagtgttcactggcaggagtcggaattgagatgggcgattggcaggaagtctgggatgagaacacgggatgttattattattggaatacacaaacaaatgaagtgacttgggagttaccccaatatcttgccacacaggtacagggattacagcattaccagcccagttctgtgccaggtgctgaaactagttttgtggtaaatacagacatatattctaaggagaaaacgatttctgtttccagtagtaaaagtggaccagtcatagccaagcgagaagttaaaaaggaagtaaatgaaggaattcaggctctctcaaatagtgaggaggagaagaaaggggtggcagcatcgctgcttgctcctttattgcctgagggaataaaagaagaagaagagagatggagaagaaaagtaatttgtaaagaggagccagtttcagaagtaaaagaaacaagtacaacagtagaagaagcaacaacaatagtaaagccacaggaaattatgttggacaatatagaagacccttctcaggaggatctttgcagtgttgtccaatctggagaaagtgaggaggaagaggaacaagatacccttgaactggagctagttttggaaaggaaaaaagcagagttgcgagccttggaggaaggagatggtagtgtgtcagggtctagtccacgttctgatatcagccagccagcatctcaagatggaatgcgtaggcttatgtctaaaagaggaaaatggaagatgtttgttcgagctaccagtccagaatctaccagtaggagttctagtaaaactggacgagatactccagaaaatggagaaactgcaattggtgctgaaaattcagaaaaaatagatgagaattcagataaagagatggaagtagaagaatctccagagaaaataaaagtacagacaacaccaaaagtagaagaagaacaggatttgaaatttcagattggagaactggcaaataccctgacaagtaaattcgagtttctaggcattaatagacaatccatctccaactttcatgtgctgctcttacagactgagactcgaattgcagactggcgggaaggggctcttaatggaaactaccttaaacgaaaacttcaggatgcagcagaacaactaaaacagtatgaaataaacgccactcctaaaggctggtcctgccactgggacagggatcatagacggtatttctatgtaaacgaacagtcgggcgagtctcagtgggagtttccagatggtgaagaggaagaagaagaaagccaagcacaagaaaatagagatgagactcttgccaaacagaccttgaaagacaaaactggcactgattcaaattcaacagaatcctctgaaacttccacagcagttaatgaactgaagaggcttgatcgtagttctggataggtggctccactcctgaccactgtcaacatcccttatatgttccaaagttgaaaattccactgttaccaattctgaatgttctgtgaacactttagatgagtattaagctgttttctccctttatgacacacatagttgatactgtctggtaaaaggaggctcttgagccattcctatttaattaaaacagaactagttgtagtgtaggaaaaagccactgataaaacaggttatattcttaagcctctctttattgagaacccctagaattgcaggataaacttgatcgaagtaaaatccaaatcttacactaagttctgtgagatttaagagcaataatcaacagttctaagcctaataaagagagctcttaatcagctcagtggtggttaaaaccagctatcttttaaagaagagaaaaaacaaaacacagcaatgccctgtctcttcagaaaattgttttaaaaagttagccaggcatagttagtggcccacgcctgtagtccgagctgtttgggaggttgaggtgggaagattggttgagcccaagattttgaggctgcagtaagccataattgtaccactgcactccagcctgagcgacagagaacaagaccctgtctcaaaaataaagtgggggaaggggtgcaaaattacactgtgagaagccaagaagtttcaaagttctatttatttttctaagtcatttttaatcattatttgttgtttcagtgtttgaatttaacattatgtttttaaagatggagtggattctaaagatgagttgggttcaagatatccaacatatcttttatattgggcttatgtcacttaggtgaagttgagctcctttttctttttaatctccatggaacaatttgtataatttcttgatttaaattgctaaactgagctcttcattcaaaatactaaacaataatttctctttggggggaaaattaaggaaggctttctatacatagaaataaagatgcctaggccgggtgcagtggctcatgcctgtaatcccaatactttggggggctgaggcgggtggatcacctgaggtcaagagttcaagaccagcctgggcaacatggtgaaaccctgcctctactaaaagtacaaaaattagctgggcgtggtggcagctgcctgtaatcccagctactcggaggctgaggcacgagaatcacttgaacctgggaggcgaaggttgcagtgaaccaagatcatgccattgcactccagcctgggcgacagagcaaaactctttatctaaaaaaaaaaaaaaaaaaaaaagacgcctacagaagcaaggttcttaggtgcagtgactcatgcctgtaattccagcactttgggagtttgaggcaagaggatcacttgagctcaggaattcaaaaccagcctgggcaatatggcaagaccccatctttgcagaatattagcctagcttggtagcacgagtatgtggtcctagctacttggaaggctgaggtgggaaggatcacttgagcctggtaggttgaagctgcagtgagctatattcacaccattgcactctagcttgaacaacaaagtgagatcctgtctcaaaaagaaaaaggaaaaattacagctcacggctgtaatcccagcactttgggaggccaaggcgcgcagatcacttgaggtcaggagtttgagaccagccaacatggtatcaccctgtctctactaaaaatacaaaaattagccaggtgtcgtggcgggtgcctgtaatcccagctactcgggaggctgaggcaggagaatcgcttgaacccaggaggcagagattacagtgaaccaagatgacacctctgcactccagcctgggcaacaggcttaaagactccgtcttaaaaaaaaattaagaatttgtattctcataacatattcagttttaagcttgtagcttttaaatctttgagcacgtaataaaagctgcgtaggccaagtgtggtggctcatgcttgtaatcccagcactttgggaggctgaggcaggaggatcacctgaggtcgggagttcaagagcagcttacccaatatgtagaaaccccgcctctactaaaaatacaaaattagccaggcgtggtcgcatgcctgtaatcctagctactcgggaggctgaggcaggagaatcattgaacccaggaggcggaggttgtggtgggccaatatcacaccattgcactccaacctgggcaacaagagcaagagtccatctaaaaaaagagctgtatataccactttaatctgtccttgggcttcagacttaaatattctcttaaacagcaaaaatactaactaagttaaatttaaaagcaaggagaagcatcattgtaatacgacatccatgtgtattcaaactagaattttctgatggtcttcgtaagataaaggagataattgtcatttctatgacacagcttttataatttgaataaacttagttggagattggagtatttttattatttattttcatgtgagatgggtaatgtgctgacctcataacaaagtttgagggagacacattgtatgtgagaatttgaagtgcttatgaagtacaaaagcagaggccaggtgctcacatctgtaatcccagcactttgggaggccaaggcacacagatcacttgaggtcaggagtttgagaccagcctggccaacatggcgaaaacccctctcttactaaaaatacaaaaattagctggatgtggtggtgtgggcctgtaatcccagctactcgcgaggctgaggcaggagaatcgcttgaacctggcaggcagaggttgcggtgagccaagattgcgtcactgcactccggcgtggacaagagagtgagactccgtcacaaaaaaaaaaaaaaaagaagaaaagtattggattcacatattctaaaaatgctcgtcatttgtggctaattttatcaagtctagtttaatctcatatttacagagtttagttaattctaattagctttgttggaggtcataaaccacattattaaccttgaaccgactctgtgtttacttgagttcctctgcataatagcatgtcaccaccatcataaacatgttggtattgcattatgcttctagaggagacatccaccaatatttgaaaatctggctggtccgagtgcagtggtgtttacaactaattgatcacaaccagttacagactttgtttcttctccagtcctgctgcttcacttgactagccttttaaaaaaaagaaagaaaatagagaaaatcttaacttatatttacttactgtatgttgtgattagtttaatagaagggagtttaatccttaataattaagttagtcctcaacgtttattgacttagttctgatgtagtccttgtgtactattgtataatgtagactacttggccatacttgattttgtctaaaagttaatgcataaattaatattaaatatggccaaatataaaagtttaatgagtcatttgaggtcatttagccagaaaactgcatttatgttcctggtgaatttttttcaatgtccttttccaaaagtggcagtaagcagctgtcttaaaataaggagacagtgggaatgatgttgttaaagtcttttatacaatgtattgtctgtctgttccataaaaagtaaaactactctattcgtgaccagcttgggcaacatagtgagactgtctctttaaaaaaaaaaaaaaaaaaaaaaattaaaaattagcaggtgtggtgatgcacacctgtagtcctagcaattcgggaagctgaggtaggaagatcgcttgagccaagtgtttgaggttagaatgagctatgatcgcaccacctacactccagcctgggcaacagagcaagacccaaatggctcatggttgctttgtttgttttaccttgttgagtgccagtgtgtattttgagcaaagcagtgtaaatggccttcttgccctagagtctttcataattgagccttatttaatctaccacttttgaccatgaaatttaacaggtgacttcttctgggtatctactccaggtgaagtgatattttttttgactgagatgtctaaagctcttggattcctggtatctcaccaggacatcttagtaaaacagcaagtatcagatgaggaatcagacttgagttctagctctggtctggccactaacattgatatgatcttgggcaagttagttcctgcctgggtttcattacctttaactgaggaggttgaaatagatgatttctcatgtctcttctactcctaaattctatgattttagggagaaaatccccttcaacattcctgggatatatatctaatagtcccatatattgtgaaacttccctattgacgataaagagggctggggaaggctacaagtaagtatatcctattttctctaatctttaaaggttttcccagcagagaaaagacagtaatcaatgatggcttttacaaagtttgaggaaagctgatcctgcaacttttcagctgcaatttcgtaatgtagacttcagcaacagcaatttcaaaaccactgcagttttaaaaaatctgagttatatactttgaagatttatcttcctaaatttctcttttatcgcaaaagtaaaaattgccatccctaacttgtgtctctgtgatatcacaaatgaatgtaatgtatgcaagggtgtgaaggaatgatatagttgacagtagcaccttgcaaatggattttttaaatttagtaacccaaattaaacacaatgggtagaactttcccgagtattttgaatgaatattctgggttgtctttactcactttgtctagctcactaaaaaataaagtatgtgtaataattactgcaggtgcacattattcactcactccttcacttttgaaatagactccagactattaccttttatttgtgtatgttgaagcttgtgagtgtttgaaatcaaaaacttcaaactacagattcagatgactgcatttctcgttgagttgatgtaatattcttctactcatccataaatatggacccgaaggacaagtataatacagatggggaaggtgctatgaagttcataaatttatctttccgtggaagtcatttctgaactgagttgttcaatattttagcgatatcagtatagaatagatgcctgtgggccaaatttttttcaaggaaggagccattccctgctgtttgacaccacattctgtattgttttgtacactgtgctaggttcctataaatgattatcttactgaccagttgaacatttctatgaatataagccagggagtttttttcttgctttttccctgactcttacctgttttcataggttctctttgtaaagaatccttttctggtcaagtttcttcttcatcactcatgccacttactccattctggaccctccttca

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