LOCUS       XM_054365660            1512 bp    mRNA    linear   PRI 26-AUG-2024
DEFINITION  PREDICTED: Homo sapiens mohawk homeobox (MKX), transcript variant
            X5, mRNA.
ACCESSION   XM_054365660
VERSION     XM_054365660.1
DBLINK      BioProject: PRJNA807723
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_060934) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_009914755.1-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1512
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /isolate="CHM13"
                     /db_xref="taxon:9606"
                     /chromosome="10"
                     /sex="female"
                     /cell_line="CHM13htert"
                     /tissue_type="hydatidiform mole"
                     /note="haploid cell line"
     gene            1..1512
                     /gene="MKX"
                     /gene_synonym="C10orf48; IFRX; IRXL1"
                     /note="mohawk homeobox; Derived by automated computational
                     analysis using gene prediction method: Gnomon. Supporting
                     evidence includes similarity to: 8 ESTs, 3 long SRA reads,
                     and 100% coverage of the annotated genomic feature by
                     RNAseq alignments, including 3 samples with support for
                     all annotated introns"
                     /db_xref="GeneID:283078"
                     /db_xref="HGNC:HGNC:23729"
                     /db_xref="MIM:601332"
     CDS             376..1263
                     /gene="MKX"
                     /gene_synonym="C10orf48; IFRX; IRXL1"
                     /codon_start=1
                     /product="homeobox protein Mohawk isoform X2"
                     /protein_id="XP_054221635.1"
                     /db_xref="GeneID:283078"
                     /db_xref="HGNC:HGNC:23729"
                     /db_xref="MIM:601332"
                     /translation="

MNTIVFNKLSGAVLFEDGGASERERGGRPYSGVLDSPHARPEVGIPDGPPLKDNLGLRHRRTGARQNGGKVRHKRQALQDMARPLKQWLYKHRDNPYPTKTEKILLALGSQMTLVQVSNWFANARRRLKNTVRQPDLSWALRIKLYNKYVQGNAERLSVSSDDSCSEDGENPPRTHMNEGGYNTPVHHPVIKSENSVIKAGVRPESRASEDYVAPPKYKSSLLNRYLNDSLRHVMATNTTMMGKTRQRNHSGSFSSNEFEEELVSPSSSETEGNFVYRTVENLGSLSEDSWDFLK"

     misc_feature    order(589..603,607..609,664..666,682..684,721..723,
                     727..732,739..744,748..756,760..765)
                     /gene="MKX"
                     /gene_synonym="C10orf48; IFRX; IRXL1"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:238039"
     misc_feature    order(595..597,604..606,730..732,739..744,751..753)
                     /gene="MKX"
                     /gene_synonym="C10orf48; IFRX; IRXL1"
                     /note="specific DNA base contacts [nucleotide binding];
                     other site"
                     /db_xref="CDD:238039"
     misc_feature    640..756
                     /gene="MKX"
                     /gene_synonym="C10orf48; IFRX; IRXL1"
                     /note="Homeobox KN domain; Region: Homeobox_KN; pfam05920"
                     /db_xref="CDD:428673"
ORIGIN      

aggcaaagggtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtatgcgcgcgcgcgtgtgttagtggagtagcagcccatgccgcggctgggcgggcaaagggggcgctggcagcgaagctgaggccgctcggaggaaacgggagctgtcccgaggcgcgaggcgaggagatggggcgggcgaagtccgccgcgcgccttggggctgtaactctgcggctccgcggccgcgcggacttgctcctgacgcccgtgcgcggcaggcagaggctcagggcctccgcgaccccagagaagccgagccccgctgcggagctcccggcggcccagccccgaggctctgcggccgcgccgcgcgtccctaccaaccgacaccatgaacaccatcgtcttcaacaagctcagcggtgcggtgctgtttgaggacggaggcgcctcggagcgggagcggggtggccggccctacagcggtgtcctggacagtcctcacgcccgccccgaggtgggcattcccgacggcccgcccctcaaggacaacctcggcctgagacaccggaggaccggcgcccggcagaatggcgggaaggtgaggcacaagcggcaggccctgcaagacatggcgcgacccctcaagcagtggctttacaagcaccgtgacaacccgtaccccaccaagaccgagaagatactcttggccctcggctcgcagatgacgctagtgcaggtgtcaaattggtttgctaatgcaagacgtcggcttaagaataccgttcgacagccagatttaagctgggctttgagaataaagttatacaacaagtatgttcaaggcaatgctgaacggcttagcgtaagcagtgatgactcatgttctgaagatggagaaaatcctccaagaacccacatgaacgaagggggctataataccccagttcaccatcctgtgattaaaagtgagaattcggtcatcaaagcgggagtgaggccagagtcacgggccagtgaggactacgtggcaccccccaaatacaagagcagcttgttgaaccgttaccttaatgactctttgagacatgtcatggccacgaacactaccatgatgggaaaaacaaggcaaagaaaccactcgggatcttttagctccaatgaatttgaggaagaattagtgtctccatcgtcatcagaaactgaaggcaactttgtctatcgcacagtggaaaacttaggttctttgagtgaggactcctgggattttttaaagtaaaaacaaggagctaagaattccactccttcttgccaatatttccttcaagcaaaattattgattaatggaaaattaaatatcatatgcttcatattgcttttttacccttttgtacttgggttattttaataattttcgctagcgctacaaatgtaattgactaaaattatacatcaaaataaaacaaaaccatgggagggaaaagattatcatattttgaaaacatatcaataaagtacatatttaaat

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