LOCUS       XM_054364924            6003 bp    mRNA    linear   PRI 26-AUG-2024
DEFINITION  PREDICTED: Homo sapiens NK2 homeobox 3 (NKX2-3), transcript variant
            X3, mRNA.
ACCESSION   XM_054364924
VERSION     XM_054364924.1
DBLINK      BioProject: PRJNA807723
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_060934) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_009914755.1-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6003
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /isolate="CHM13"
                     /db_xref="taxon:9606"
                     /chromosome="10"
                     /sex="female"
                     /cell_line="CHM13htert"
                     /tissue_type="hydatidiform mole"
                     /note="haploid cell line"
     gene            1..6003
                     /gene="NKX2-3"
                     /gene_synonym="CSX3; NK2.3; NKX2.3; NKX2C; NKX4-3"
                     /note="NK2 homeobox 3; Derived by automated computational
                     analysis using gene prediction method: Gnomon. Supporting
                     evidence includes similarity to: 1 mRNA, 2 ESTs, 7 long
                     SRA reads, and 81% coverage of the annotated genomic
                     feature by RNAseq alignments, including 8 samples with
                     support for all annotated introns"
                     /db_xref="GeneID:159296"
                     /db_xref="HGNC:HGNC:7836"
                     /db_xref="MIM:606727"
     CDS             5418..6002
                     /gene="NKX2-3"
                     /gene_synonym="CSX3; NK2.3; NKX2.3; NKX2C; NKX4-3"
                     /codon_start=1
                     /product="homeobox protein Nkx-2.3 isoform X1"
                     /protein_id="XP_054220899.1"
                     /db_xref="GeneID:159296"
                     /db_xref="HGNC:HGNC:7836"
                     /db_xref="MIM:606727"
                     /translation="

MMLPSPVTSTPFSVKDILNLEQQHQHFHGAHLQADLEHHFHSAPCMLAAAEGTQFSDGGEEDEEDEGEKLSYLNSLAAADGHGDSGLCPQGYVHTVLRDSCSEPKEHEEEPEVVRDRSQNAQDPNKHALTTPLHETRLRLLRAFFGYWGCLRVPQRQEPQTFPKVQPFTTARSAQPPKRVTVLQDRSRGAAGNS"

ORIGIN      

aaatgggcaggagggaaacaggtggggaggagtggaaacagtaagaaaggaagctgaggagatgggggaggaggtgaggaagaaaggaagtgggggaagggcagaagggaaaaggggtggcagagtaaaatgggctccgtcagagaggaaggggctacgagggggaaaaggctagcagtgagggagaggaggaggactgcaggcggaagagcgcgcgcgttttaggatccccgactcagaagctctgcctggcctcaggatgtggcgagcctcaagagacggtttgaaggtatttgtgccaacgtgacccccagggagatttggaggaagctttctacgtcctaggaggctgagatcccacggagccggtttacggttgagagcagacagtttcgagtagatagcgctggaagagacacgaagaatctctcttgcttcttggaacgcgataaccacatttctttctctgttcccccactactaaaaatcagcaatccgcacagagcaggcagccgctctggttcgaatgaattaatttgcccaagacagcagccgctcttctgaagtcagattacatttttaaaagtttatacacattgaaatttcgctacagaaagttaaaagcaggctagcaacaacaaaaaagttaaggaatgcattcagaattccaatttaatcctcaagttaaaactgctcactgcacgcccaaatagcacacgcaaacagtacaaataaatgtctgtatacaggagtcctttatttagttgtttttcgtttgaaaaaatattgaattgattttcattcaacaaagatacagtcttttcgacatgttttattaacagaactggttttggtaaagaaagggtaatttacatttttatctttaaaatttttggaggggcagatccacaaagatagctgtgaagtcctctccctgagaaatcgaaagtcacattctcagcaaggacctgtaatttacaaggaactatacaaattactgtattcggactaattttctcccaggaaagagaaatagtggttaatttagaaaactcaattccaaataaaatctaggaaaatttggcattcctgcaaacacatgcaaaacaaactagtgcttaaaacagcatttcaaaatctcttttatgaaattccttcgacaagaaaaaaacctcccaagaaattagaacagtttaatgccttctaggactcactaacctagttgacattaaaagcacaaaatgtattcacccgtctcgcaattaaaatgctattgcttctgaattgctttaaaaaaaatggatagctttctaacattccttaacaaaaaaccaaagcaaagcacacttgcgcatacacacaaacacacacacccaccaccaccaccaccaccatcactaccaccaacaaattaacaaaaacccatttagtgagtctctctctcataagttgacattgaaagtgaaacttctaggagagcaattaaaaaaatgaaaagattcacctgaaatgttttggctatctgagttcatcacaggatgattttttcaggctttaatagaaaaatctcttctgattgtagtgttacattgttacattttgattagaaagccacgataactttcaacttgtttgcagccttggttacataattaaatgacaatttgaaaagttgagagacaacgggataagcagtggcatttacaactaaaattatccattatctgcctatatttatatgtgcattaagcaatctttgtgtagacaataacagctatgagaacacttaacagttttcaaaaaattgtcacatttttcatttgataatgcatttattgtaatggctagcatgtggttttccttaaaaaaaaaaaaaaaggtacagacgtttaggcatctatacagcacttccccttcaaggactttgccaccatttactgatgatctttaatcatagggtgggggagagagcttgtataaatgtatgaggtgatgaaagggtaggaaggcagatacactcgattaaaataaaatcaaacgcttccatggatgcagccatacttactttatctgacagtaattagctaaactgtctggaacgaaaacctattattagtagagcacagctcgaggatttcaaagatctacttttcagacaagagaatgcaaatgccccagaagccgatggtaactggataggcgttggaaccagatcccactctgataagagagtcctgcggagcgactgctgctgtacaactaccgctctcgagttctcctcctttcaggcccgcggccgtcgagggtacaggctgcgcgcgcgggaaaaggaggccacctagatgagattggcctggcggggatccctgcggggaagcacgccactggggaaccagaccaagggagtctgaacaatactgagggggtagctggagacaacccaaactcctgctctgggcataaaactcagatcaaccttagggatgcggtagcggatagaggttttccgcaggctggaacagcactgcactgggctgggtatgaggaaaggaagcggcgataaggtctaggcgccgcccgctaggccccttcgcctggaagtcctcacaggccctggtggcctactgaggagcaacctgcccagggtcctcaagagacaaccgcttaggcctggcgcaaggtacctggcccgggagcggctggggcggcggaatttggggtagaggggcacccgtgggccggctggtggggaggagacagccccctgcatgagctcacagaggcgccctggtgggctccggcggctgcagagcgtctgtgggcgtgtatcggcgatcaggcgctggaggggcgctttgtcctggtcgcagttttaagacctggattgttgggctagatttatgaaaggcctaggagcgaagcgagatgggaagcaagggaatgtaacaaggagaaatgcaggcttcggttggaaactggggagagagagattgtttcgatagcctttctccttttctttttccagaatcatgaaatcaccgaggagaagaaaactggggactagaagagagcagaaacatttcccctgagacagttttgccccggaggtggggtggggaagtggcgctggagctcagcttcctgcttttatgctcggcggccaccgtgatgcacacacactcgaggtccgccaccccgcagtgccgtgcacccctctgcccccacctcggaatttttgtgcccgagcgctcgggatccacggcaaaaccaggcacattcctccctctgcagactcaccgcctggtttgtagacactggtctccgcctggggcgtcaatagtttcaggatttaaagcagaaagacaccgggcgcccctgtggctgaggaatggcggttccagcacaagaccctgcccacagagggtctctccctactgcctgcgggccgccgctaccctaagtactccggggcgcacgtggcccgcgcggcatcccagctccccgggcggacccaggggctgcctctccacaacagttccgctcccttctgcagagccccgcctctcccacctcccgacaggctgttctttctcccttcaaccttgggcacccactcctgtcgccgttgcgggacccgcgtggcagccctccaccctcgtacccactcccagccggtgtcttatgccgctcggaggcaatgtccaccgtccctgcacctttcacctgccccttccaggtgagacgggtctctttcagctccgccatcctgaccgccaaaaaatgcttggattggctggggccggatgaggacagccacggttgagctggaaccgttccctatttttttaaggccagcgctgcacacgggtctttctgtggccctcaaagcagcgcctgctgctcctcactgggctaggcctggtagcgagcaaatgcctattgtgggagaagatggtcccagagtttccagctcagagtttccagaatctgtgggggactgcatagactcccccagaaaacaaccagggcctcatgaaggtgccagaaggcgtgtaggtagagaaattttaaaagcctgtcggagaggcaaggcctacattcaggctcctgatttcaataggcggaaaagaaggctgccaaggctgggtcacctcccttgtgaggacagatcctgctctcagtatgtgccacactccagccacgcaccaccaatgcagtcaacaaacactgcttgacctcccatacagaaaagcagtcgttgacacgtactgagcgcttaacacgcgtgaggccgtgcactaagattctggcatgttttgcctcattcaaccctagcaacaaccaaaaaaggtattactgccttcgttttatagacgagaaaacagacttagaaacgccgaagatcacacactgactaggccaagcaagagctgtcgaataccaaagtttagtcataactctatcttcctttcacatactgctctgtgcggctgctgccagggatacaagggcaaaagcaaccccgggacactgccctcatggagcttacagtctaactggggcgaccaggcaggcacatacagctatagaattaagtgggaagtgataagtgacatgcatgtcctttgctaacacaagctgcaggttcagagcctgaaagaggggacttccggctagacgatctaggagctcttccttggagaacagtttccactcgtggaggctaagtgtcagaaacatgttccaagtggagagaaagcttgagcaaaggcaacaagttgaaaaaggacatgtcgcccacccatagatagataaaacactgcatctcctcgtggatccagcgcccagtatttacccgccaggaagttttcctgccccgcgcagcagctgaaaaaaacacactcctggggcatccttctctggcgttggttcgtggacagcaagcctcccagaactggcctaggtcgggaaggtgcagccacgagggaatcaatggttcaggaaccggatcaatgcagcctcgcccgcagcgtctcggacttcaggactctatactagtccttgtctatttctggtagagccgcaacatcccactcgcagagagcagggggcgtggcccacatgagccagaacctatagggagggaggttggggcgccagccccgcccccccaacgtgacgcaaatctcccggacagaggcttaggagcccgggccccagtccctgcagtggctgtaacaaaacccagacccccaggtcccggccaatggaggcgatttagactggagtgggaccgcgtctgtcaaaagcccgactcggcagcagcggcggagtccaggaggagagctggagccgccgcgctgcctccccgcccccgccgggatttattatttggactggacaattaagtggccctgatgatgttaccaagcccggtcacctccacccctttctcagtcaaagacattttgaatctggagcagcagcaccagcacttccatggtgcgcacttgcaggcggacttggagcaccacttccactctgcgccctgcatgctggccgcagctgaggggacgcaattttctgacggaggggaggaggacgaggaagacgagggcgagaaattgtcctatttgaactcactagccgcagcagacggccacggggattcagggctgtgtccccagggctatgtccacacggtcctgcgagactcgtgcagcgagcccaaggaacatgaagaggagcccgaggtcgtgagggaccggagccaaaatgctcaagatccaaataaacacgcactaactacccctctccacgaaacgcgcctccgcctgctaagggcgttctttgggtactggggctgtctcagggtcccacagcgccaggagccacaaacgttcccaaaagtccagccatttactaccgcacgctctgcgcagccaccaaaaagggtcacggtgctccaggacaggagccgcggtgcggccgggaacagctaag

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