2024-05-03 04:49:03, GGRNA.v2 : RefSeq release 222 (Jan, 2024)
LOCUS NR_039668 68 bp RNA linear PRI 23-JAN-2022 DEFINITION Homo sapiens microRNA 3135b (MIR3135B), microRNA. ACCESSION NR_039668 VERSION NR_039668.1 KEYWORDS RefSeq. SOURCE Homo sapiens (human) ORGANISM Homo sapiens Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. REFERENCE 1 (bases 1 to 68) AUTHORS Wang F, Li Z, Zhao M, Ye W, Wu H, Liao Q, Bu S and Zhang Y. TITLE Circulating miRNAs miR-574-5p and miR-3135b are potential metabolic regulators for serum lipids and blood glucose in gestational diabetes mellitus JOURNAL Gynecol Endocrinol 37 (7), 665-671 (2021) PUBMED 34126831 REMARK GeneRIF: Circulating miRNAs miR-574-5p and miR-3135b are potential metabolic regulators for serum lipids and blood glucose in gestational diabetes mellitus. REFERENCE 2 (bases 1 to 68) AUTHORS Shi J, Ren Y, Liu Y, Cheng Y and Liu Y. TITLE Circulating miR-3135b and miR-107 are potential biomarkers for severe hypertension JOURNAL J Hum Hypertens 35 (4), 343-350 (2021) PUBMED 32327699 REMARK GeneRIF: Circulating miR-3135b and miR-107 are potential biomarkers for severe hypertension. REFERENCE 3 (bases 1 to 68) AUTHORS Hu W, Xu B, Zhang J, Kou C, Liu J, Wang Q and Zhang R. TITLE Exosomal miR-146a-5p from Treponema pallidum-stimulated macrophages reduces endothelial cells permeability and monocyte transendothelial migration by targeting JAM-C JOURNAL Exp Cell Res 388 (1), 111823 (2020) PUBMED 31926946 REFERENCE 4 (bases 1 to 68) AUTHORS Enomoto Y, Takagi R, Naito Y, Kiniwa T, Tanaka Y, Hamada-Tsutsumi S, Kawano M, Matsushita S, Ochiya T and Miyajima A. TITLE Identification of the novel 3' UTR sequences of human IL-21 mRNA as potential targets of miRNAs JOURNAL Sci Rep 7 (1), 7780 (2017) PUBMED 28798470 REMARK Publication Status: Online-Only REFERENCE 5 (bases 1 to 68) AUTHORS Jima DD, Zhang J, Jacobs C, Richards KL, Dunphy CH, Choi WW, Au WY, Srivastava G, Czader MB, Rizzieri DA, Lagoo AS, Lugar PL, Mann KP, Flowers CR, Bernal-Mizrachi L, Naresh KN, Evens AM, Gordon LI, Luftig M, Friedman DR, Weinberg JB, Thompson MA, Gill JI, Liu Q, How T, Grubor V, Gao Y, Patel A, Wu H, Zhu J, Blobe GC, Lipsky PE, Chadburn A and Dave SS. CONSRTM Hematologic Malignancies Research Consortium TITLE Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs JOURNAL Blood 116 (23), e118-e127 (2010) PUBMED 20733160 REFERENCE 6 (bases 1 to 68) AUTHORS Griffiths-Jones S, Grocock RJ, van Dongen S, Bateman A and Enright AJ. TITLE miRBase: microRNA sequences, targets and gene nomenclature JOURNAL Nucleic Acids Res 34 (Database issue), D140-D144 (2006) PUBMED 16381832 COMMENT PROVISIONAL REFSEQ: This record is based on preliminary annotation provided by NCBI staff in collaboration with miRBase. The reference sequence was derived from AL672104.4. Summary: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]. Sequence Note: This record represents a predicted microRNA stem-loop as defined by miRBase. Some sequence at the 5' and 3' ends may not be included in the intermediate precursor miRNA produced by Drosha cleavage. PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-68 AL672104.4 14255-14322 c FEATURES Location/Qualifiers source 1..68 /organism="Homo sapiens" /mol_type="transcribed RNA" /db_xref="taxon:9606" /chromosome="6" /map="6p21.32" gene 1..68 /gene="MIR3135B" /note="microRNA 3135b" /db_xref="GeneID:100616218" /db_xref="HGNC:HGNC:41783" /db_xref="miRBase:MI0016809" precursor_RNA 1..68 /gene="MIR3135B" /product="microRNA 3135b" /db_xref="GeneID:100616218" /db_xref="HGNC:HGNC:41783" /db_xref="miRBase:MI0016809" exon 1..68 /gene="MIR3135B" /inference="alignment:Splign:2.1.0" variation 3 /gene="MIR3135B" /replace="c" /replace="t" /db_xref="dbSNP:1315019912" variation 4 /gene="MIR3135B" /replace="c" /replace="g" /replace="t" /db_xref="dbSNP:935902905" variation 5 /gene="MIR3135B" /replace="c" /replace="t" /db_xref="dbSNP:1292500923" variation 6 /gene="MIR3135B" /replace="a" /replace="g" /db_xref="dbSNP:1763852998" ncRNA 7..28 /ncRNA_class="miRNA" /gene="MIR3135B" /product="hsa-miR-3135b" /db_xref="miRBase:MIMAT0018985" /db_xref="GeneID:100616218" /db_xref="HGNC:HGNC:41783" /db_xref="miRBase:MI0016809" variation 7 /gene="MIR3135B" /replace="a" /replace="g" /db_xref="dbSNP:1763852845" variation 8 /gene="MIR3135B" /replace="c" /replace="g" /db_xref="dbSNP:1437307191" variation 9 /gene="MIR3135B" /replace="c" /replace="t" /db_xref="dbSNP:1202765326" variation 11 /gene="MIR3135B" /replace="a" /replace="g" /replace="t" /db_xref="dbSNP:905889141" variation 14 /gene="MIR3135B" /replace="a" /replace="g" /db_xref="dbSNP:922757991" variation 15 /gene="MIR3135B" /replace="c" /replace="t" /db_xref="dbSNP:1562200624" variation 16 /gene="MIR3135B" /replace="a" /replace="g" /db_xref="dbSNP:1763851794" variation 19 /gene="MIR3135B" /replace="c" /replace="t" /db_xref="dbSNP:1763851618" variation 20 /gene="MIR3135B" /replace="a" /replace="g" /db_xref="dbSNP:1582355093" variation 30 /gene="MIR3135B" /replace="a" /replace="c" /db_xref="dbSNP:1763851286" variation 35 /gene="MIR3135B" /replace="a" /replace="g" /db_xref="dbSNP:4351242" variation 37 /gene="MIR3135B" /replace="c" /replace="t" /db_xref="dbSNP:1333711317" variation 42 /gene="MIR3135B" /replace="a" /replace="c" /db_xref="dbSNP:1275371288" variation 44 /gene="MIR3135B" /replace="a" /replace="c" /db_xref="dbSNP:1232188346" variation 46 /gene="MIR3135B" /replace="c" /replace="t" /db_xref="dbSNP:1368590309" variation 47 /gene="MIR3135B" /replace="c" /replace="t" /db_xref="dbSNP:1322132038" variation 49 /gene="MIR3135B" /replace="c" /replace="g" /db_xref="dbSNP:950049808" variation 52 /gene="MIR3135B" /replace="a" /replace="c" /db_xref="dbSNP:1763849953" variation 55 /gene="MIR3135B" /replace="c" /replace="t" /db_xref="dbSNP:4285314" variation 56 /gene="MIR3135B" /replace="a" /replace="g" /db_xref="dbSNP:1763849458" variation 61 /gene="MIR3135B" /replace="c" /replace="t" /db_xref="dbSNP:1763849268" variation 64 /gene="MIR3135B" /replace="a" /replace="g" /db_xref="dbSNP:1387253703" variation 67 /gene="MIR3135B" /replace="a" /replace="c" /db_xref="dbSNP:983514346" variation 68 /gene="MIR3135B" /replace="a" /replace="t" /db_xref="dbSNP:1164940570" ORIGIN
tgcccaggctggagcgagtgcagtggtgcagtcagtcctagctcactgcagcctcgaactcctgggct
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@meso_cacase at
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This page is licensed under a
Creative Commons Attribution 4.0 International License (CC BY 4.0).
If you use GGRNA in your work, please cite:
Naito Y, Bono H. (2012)
GGRNA: an ultrafast, transcript-oriented search engine for genes and transcripts.
Nucleic Acids Res., 40, W592-W596.
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