ver.2
Home
|
Help
|
Advanced search
Previous release (v1)
2026-10-05 19:52:11, GGRNA.v2 : RefSeq release 233 (Jan, 2026)
LOCUS NR_031720 50 bp RNA linear PRI 11-SEP-2020
DEFINITION Homo sapiens microRNA 1539 (MIR1539), microRNA.
ACCESSION NR_031720
VERSION NR_031720.1
KEYWORDS RefSeq.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 50)
AUTHORS Azuma-Mukai A, Oguri H, Mituyama T, Qian ZR, Asai K, Siomi H and
Siomi MC.
TITLE Characterization of endogenous human Argonautes and their miRNA
partners in RNA silencing
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 105 (23), 7964-7969 (2008)
PUBMED 18524951
REFERENCE 2 (bases 1 to 50)
AUTHORS Griffiths-Jones S, Grocock RJ, van Dongen S, Bateman A and Enright
AJ.
TITLE miRBase: microRNA sequences, targets and gene nomenclature
JOURNAL Nucleic Acids Res. 34 (Database issue), D140-D144 (2006)
PUBMED 16381832
COMMENT PROVISIONAL REFSEQ: This record is based on preliminary annotation
provided by NCBI staff in collaboration with miRBase. The reference
sequence was derived from AC100778.5.
Summary: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs
that are involved in post-transcriptional regulation of gene
expression in multicellular organisms by affecting both the
stability and translation of mRNAs. miRNAs are transcribed by RNA
polymerase II as part of capped and polyadenylated primary
transcripts (pri-miRNAs) that can be either protein-coding or
non-coding. The primary transcript is cleaved by the Drosha
ribonuclease III enzyme to produce an approximately 70-nt stem-loop
precursor miRNA (pre-miRNA), which is further cleaved by the
cytoplasmic Dicer ribonuclease to generate the mature miRNA and
antisense miRNA star (miRNA*) products. The mature miRNA is
incorporated into a RNA-induced silencing complex (RISC), which
recognizes target mRNAs through imperfect base pairing with the
miRNA and most commonly results in translational inhibition or
destabilization of the target mRNA. The RefSeq represents the
predicted microRNA stem-loop. [provided by RefSeq, Sep 2009].
Sequence Note: This record represents a predicted microRNA
stem-loop as defined by miRBase. Some sequence at the 5' and 3'
ends may not be included in the intermediate precursor miRNA
produced by Drosha cleavage.
PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP
1-50 AC100778.5 12425-12474 c
FEATURES Location/Qualifiers
source 1..50
/organism="Homo sapiens"
/mol_type="transcribed RNA"
/db_xref="taxon:9606"
/chromosome="18"
/map="18q21.1"
gene 1..50
/gene="MIR1539"
/gene_synonym="hsa-mir-1539; MIRN1539"
/note="microRNA 1539"
/db_xref="GeneID:100302257"
/db_xref="HGNC:HGNC:35383"
/db_xref="miRBase:MI0007260"
precursor_RNA 1..50
/gene="MIR1539"
/gene_synonym="hsa-mir-1539; MIRN1539"
/product="microRNA 1539"
/db_xref="GeneID:100302257"
/db_xref="HGNC:HGNC:35383"
/db_xref="miRBase:MI0007260"
exon 1..50
/gene="MIR1539"
/gene_synonym="hsa-mir-1539; MIRN1539"
/inference="alignment:Splign:2.1.0"
variation 1
/gene="MIR1539"
/gene_synonym="hsa-mir-1539; MIRN1539"
/replace="c"
/replace="g"
/db_xref="dbSNP:557803768"
variation 2
/gene="MIR1539"
/gene_synonym="hsa-mir-1539; MIRN1539"
/replace="a"
/replace="c"
/replace="g"
/db_xref="dbSNP:772937610"
variation 3
/gene="MIR1539"
/gene_synonym="hsa-mir-1539; MIRN1539"
/replace="c"
/replace="t"
/db_xref="dbSNP:571955204"
variation 4
/gene="MIR1539"
/gene_synonym="hsa-mir-1539; MIRN1539"
/replace="c"
/replace="t"
/db_xref="dbSNP:1600482329"
variation 5
/gene="MIR1539"
/gene_synonym="hsa-mir-1539; MIRN1539"
/replace="c"
/replace="g"
/replace="t"
/db_xref="dbSNP:746336594"
variation 6
/gene="MIR1539"
/gene_synonym="hsa-mir-1539; MIRN1539"
/replace="c"
/replace="t"
/db_xref="dbSNP:1435573210"
variation 8
/gene="MIR1539"
/gene_synonym="hsa-mir-1539; MIRN1539"
/replace="c"
/replace="t"
/db_xref="dbSNP:769235959"
variation 9
/gene="MIR1539"
/gene_synonym="hsa-mir-1539; MIRN1539"
/replace="a"
/replace="c"
/replace="g"
/db_xref="dbSNP:903613346"
variation 10
/gene="MIR1539"
/gene_synonym="hsa-mir-1539; MIRN1539"
/replace="a"
/replace="g"
/replace="t"
/db_xref="dbSNP:1600482359"
variation 11
/gene="MIR1539"
/gene_synonym="hsa-mir-1539; MIRN1539"
/replace="c"
/replace="t"
/db_xref="dbSNP:1000651768"
variation 12
/gene="MIR1539"
/gene_synonym="hsa-mir-1539; MIRN1539"
/replace="c"
/replace="g"
/replace="t"
/db_xref="dbSNP:534538124"
variation 13
/gene="MIR1539"
/gene_synonym="hsa-mir-1539; MIRN1539"
/replace="a"
/replace="c"
/replace="t"
/db_xref="dbSNP:1251981192"
variation 14..24
/gene="MIR1539"
/gene_synonym="hsa-mir-1539; MIRN1539"
/replace="gc"
/replace="gcaggtagcgc"
/db_xref="dbSNP:2083777540"
variation 16
/gene="MIR1539"
/gene_synonym="hsa-mir-1539; MIRN1539"
/replace="a"
/replace="c"
/replace="g"
/db_xref="dbSNP:1028157827"
variation 18
/gene="MIR1539"
/gene_synonym="hsa-mir-1539; MIRN1539"
/replace="a"
/replace="g"
/db_xref="dbSNP:1208318181"
variation 19
/gene="MIR1539"
/gene_synonym="hsa-mir-1539; MIRN1539"
/replace="g"
/replace="t"
/db_xref="dbSNP:1600482421"
variation 21
/gene="MIR1539"
/gene_synonym="hsa-mir-1539; MIRN1539"
/replace="g"
/replace="t"
/db_xref="dbSNP:554062711"
variation 22
/gene="MIR1539"
/gene_synonym="hsa-mir-1539; MIRN1539"
/replace="a"
/replace="c"
/replace="t"
/db_xref="dbSNP:370414286"
variation 23
/gene="MIR1539"
/gene_synonym="hsa-mir-1539; MIRN1539"
/replace="a"
/replace="c"
/replace="g"
/db_xref="dbSNP:1177982731"
variation 24
/gene="MIR1539"
/gene_synonym="hsa-mir-1539; MIRN1539"
/replace="c"
/replace="g"
/db_xref="dbSNP:760277030"
variation 25
/gene="MIR1539"
/gene_synonym="hsa-mir-1539; MIRN1539"
/replace="a"
/replace="c"
/replace="g"
/db_xref="dbSNP:1245278720"
variation 26..28
/gene="MIR1539"
/gene_synonym="hsa-mir-1539; MIRN1539"
/replace="aa"
/replace="aaa"
/replace="aaaa"
/db_xref="dbSNP:1247918666"
variation 26
/gene="MIR1539"
/gene_synonym="hsa-mir-1539; MIRN1539"
/replace="a"
/replace="c"
/replace="g"
/db_xref="dbSNP:2083778171"
variation 27
/gene="MIR1539"
/gene_synonym="hsa-mir-1539; MIRN1539"
/replace="a"
/replace="c"
/db_xref="dbSNP:2083778374"
variation 29
/gene="MIR1539"
/gene_synonym="hsa-mir-1539; MIRN1539"
/replace="a"
/replace="c"
/replace="g"
/db_xref="dbSNP:773932900"
ncRNA 30..50
/ncRNA_class="miRNA"
/gene="MIR1539"
/gene_synonym="hsa-mir-1539; MIRN1539"
/product="hsa-miR-1539"
/db_xref="miRBase:MIMAT0007401"
/db_xref="GeneID:100302257"
/db_xref="HGNC:HGNC:35383"
/db_xref="miRBase:MI0007260"
variation 31
/gene="MIR1539"
/gene_synonym="hsa-mir-1539; MIRN1539"
/replace="a"
/replace="c"
/db_xref="dbSNP:2083778551"
variation 32
/gene="MIR1539"
/gene_synonym="hsa-mir-1539; MIRN1539"
/replace="c"
/replace="g"
/replace="t"
/db_xref="dbSNP:2083778614"
variation 33
/gene="MIR1539"
/gene_synonym="hsa-mir-1539; MIRN1539"
/replace="g"
/replace="t"
/db_xref="dbSNP:1202005680"
variation 34
/gene="MIR1539"
/gene_synonym="hsa-mir-1539; MIRN1539"
/replace="g"
/replace="t"
/db_xref="dbSNP:2148813010"
variation 35
/gene="MIR1539"
/gene_synonym="hsa-mir-1539; MIRN1539"
/replace="c"
/replace="t"
/db_xref="dbSNP:574136841"
variation 42
/gene="MIR1539"
/gene_synonym="hsa-mir-1539; MIRN1539"
/replace="c"
/replace="g"
/db_xref="dbSNP:2083778765"
variation 43
/gene="MIR1539"
/gene_synonym="hsa-mir-1539; MIRN1539"
/replace="a"
/replace="c"
/replace="g"
/replace="t"
/db_xref="dbSNP:368524614"
variation 44
/gene="MIR1539"
/gene_synonym="hsa-mir-1539; MIRN1539"
/replace="a"
/replace="c"
/replace="g"
/db_xref="dbSNP:1477787264"
variation 45
/gene="MIR1539"
/gene_synonym="hsa-mir-1539; MIRN1539"
/replace="a"
/replace="c"
/replace="g"
/db_xref="dbSNP:1364420621"
variation 46
/gene="MIR1539"
/gene_synonym="hsa-mir-1539; MIRN1539"
/replace="a"
/replace="c"
/replace="t"
/db_xref="dbSNP:933051089"
variation 47
/gene="MIR1539"
/gene_synonym="hsa-mir-1539; MIRN1539"
/replace="a"
/replace="g"
/db_xref="dbSNP:1600482572"
variation 48
/gene="MIR1539"
/gene_synonym="hsa-mir-1539; MIRN1539"
/replace="c"
/replace="t"
/db_xref="dbSNP:111715115"
variation 49
/gene="MIR1539"
/gene_synonym="hsa-mir-1539; MIRN1539"
/replace="c"
/replace="t"
/db_xref="dbSNP:888755072"
ORIGIN
ggctctgcggcctgcaggtagcgcgaaagtcctgcgcgtcccagatgccc
//
by
@meso_cacase at
DBCLS
This page is licensed under a
Creative Commons Attribution 4.0 International License (CC BY 4.0).
If you use GGRNA in your work, please cite:
Naito Y, Bono H. (2012)
GGRNA: an ultrafast, transcript-oriented search engine for genes and transcripts.
Nucleic Acids Res., 40, W592-W596.
[Full Text]