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2026-10-05 18:57:16, GGRNA.v2 : RefSeq release 233 (Jan, 2026)

LOCUS       NR_029854                 87 bp    RNA     linear   PRI 03-MAR-2024
DEFINITION  Homo sapiens microRNA 365a (MIR365A), microRNA.
ACCESSION   NR_029854
VERSION     NR_029854.1
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 87)
  AUTHORS   Xiang,M., Wang,Y., Chen,Q., Wang,J., Gao,Z., Liang,J. and Xu,J.
  TITLE     LncRNA NEAT1 promotes IL-6 secretion in monocyte-derived dendritic
            cells via sponging miR-365a-3p in systemic lupus erythematosus
  JOURNAL   Epigenetics 18 (1), 2226492 (2023)
   PUBMED   37343193
  REMARK    GeneRIF: LncRNA NEAT1 promotes IL-6 secretion in monocyte-derived
            dendritic cells via sponging miR-365a-3p in systemic lupus
            erythematosus.
REFERENCE   2  (bases 1 to 87)
  AUTHORS   Chen,S., Xu,Y. and Yang,B.
  TITLE     CircUSP48 promotes malignant behavior by regulating CYR61 via
            miR-365 in osteosarcoma
  JOURNAL   Funct Integr Genomics 23 (3), 270 (2023)
   PUBMED   37553503
  REMARK    GeneRIF: CircUSP48 promotes malignant behavior by regulating CYR61
            via miR-365 in osteosarcoma.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 87)
  AUTHORS   Esfandyari,D., Idrissou,B.M.G., Hennis,K., Avramopoulos,P.,
            Dueck,A., El-Battrawy,I., Gruter,L., Meier,M.A., Nager,A.C.,
            Ramanujam,D., Dorn,T., Meitinger,T., Hagl,C., Milting,H.,
            Borggrefe,M., Fenske,S., Biel,M., Dendorfer,A., Sassi,Y.,
            Moretti,A. and Engelhardt,S.
  TITLE     MicroRNA-365 regulates human cardiac action potential duration
  JOURNAL   Nat Commun 13 (1), 220 (2022)
   PUBMED   35017523
  REMARK    GeneRIF: MicroRNA-365 regulates human cardiac action potential
            duration.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 87)
  AUTHORS   Gao,Y., Miao,Y., Zhang,W., Ru,X. and Hou,L.
  TITLE     MicroRNA-365 induces apoptosis and inhibits invasion of human
            myeloma cells by targeting homeobox A9 (HOXA9)
  JOURNAL   Environ Toxicol Pharmacol 85, 103627 (2021)
   PUBMED   33621688
  REMARK    GeneRIF: MicroRNA-365 induces apoptosis and inhibits invasion of
            human myeloma cells by targeting homeobox A9 (HOXA9).
REFERENCE   5  (bases 1 to 87)
  AUTHORS   Bertoli,G., Cava,C., Corsi,F., Piccotti,F., Martelli,C.,
            Ottobrini,L., Vaira,V. and Castiglioni,I.
  TITLE     Triple negative aggressive phenotype controlled by miR-135b and
            miR-365: new theranostics candidates
  JOURNAL   Sci Rep 11 (1), 6553 (2021)
   PUBMED   33753785
  REMARK    GeneRIF: Triple negative aggressive phenotype controlled by
            miR-135b and miR-365: new theranostics candidates.
            Publication Status: Online-Only
REFERENCE   6  (bases 1 to 87)
  AUTHORS   Lui,W.O., Pourmand,N., Patterson,B.K. and Fire,A.
  TITLE     Patterns of known and novel small RNAs in human cervical cancer
  JOURNAL   Cancer Res 67 (13), 6031-6043 (2007)
   PUBMED   17616659
REFERENCE   7  (bases 1 to 87)
  AUTHORS   Landgraf,P., Rusu,M., Sheridan,R., Sewer,A., Iovino,N., Aravin,A.,
            Pfeffer,S., Rice,A., Kamphorst,A.O., Landthaler,M., Lin,C.,
            Socci,N.D., Hermida,L., Fulci,V., Chiaretti,S., Foa,R.,
            Schliwka,J., Fuchs,U., Novosel,A., Muller,R.U., Schermer,B.,
            Bissels,U., Inman,J., Phan,Q., Chien,M., Weir,D.B., Choksi,R., De
            Vita,G., Frezzetti,D., Trompeter,H.I., Hornung,V., Teng,G.,
            Hartmann,G., Palkovits,M., Di Lauro,R., Wernet,P., Macino,G.,
            Rogler,C.E., Nagle,J.W., Ju,J., Papavasiliou,F.N., Benzing,T.,
            Lichter,P., Tam,W., Brownstein,M.J., Bosio,A., Borkhardt,A.,
            Russo,J.J., Sander,C., Zavolan,M. and Tuschl,T.
  TITLE     A mammalian microRNA expression atlas based on small RNA library
            sequencing
  JOURNAL   Cell 129 (7), 1401-1414 (2007)
   PUBMED   17604727
REFERENCE   8  (bases 1 to 87)
  AUTHORS   Griffiths-Jones,S., Grocock,R.J., van Dongen,S., Bateman,A. and
            Enright,A.J.
  TITLE     miRBase: microRNA sequences, targets and gene nomenclature
  JOURNAL   Nucleic Acids Res 34 (Database issue), D140-D144 (2006)
   PUBMED   16381832
REFERENCE   9  (bases 1 to 87)
  AUTHORS   Bentwich,I., Avniel,A., Karov,Y., Aharonov,R., Gilad,S., Barad,O.,
            Barzilai,A., Einat,P., Einav,U., Meiri,E., Sharon,E., Spector,Y.
            and Bentwich,Z.
  TITLE     Identification of hundreds of conserved and nonconserved human
            microRNAs
  JOURNAL   Nat Genet 37 (7), 766-770 (2005)
   PUBMED   15965474
REFERENCE   10 (bases 1 to 87)
  AUTHORS   Xie,X., Lu,J., Kulbokas,E.J., Golub,T.R., Mootha,V.,
            Lindblad-Toh,K., Lander,E.S. and Kellis,M.
  TITLE     Systematic discovery of regulatory motifs in human promoters and 3'
            UTRs by comparison of several mammals
  JOURNAL   Nature 434 (7031), 338-345 (2005)
   PUBMED   15735639
COMMENT     PROVISIONAL REFSEQ: This record is based on preliminary annotation
            provided by NCBI staff in collaboration with miRBase. The reference
            sequence was derived from AC040173.5.
            
            Summary: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs
            that are involved in post-transcriptional regulation of gene
            expression in multicellular organisms by affecting both the
            stability and translation of mRNAs. miRNAs are transcribed by RNA
            polymerase II as part of capped and polyadenylated primary
            transcripts (pri-miRNAs) that can be either protein-coding or
            non-coding. The primary transcript is cleaved by the Drosha
            ribonuclease III enzyme to produce an approximately 70-nt stem-loop
            precursor miRNA (pre-miRNA), which is further cleaved by the
            cytoplasmic Dicer ribonuclease to generate the mature miRNA and
            antisense miRNA star (miRNA*) products. The mature miRNA is
            incorporated into a RNA-induced silencing complex (RISC), which
            recognizes target mRNAs through imperfect base pairing with the
            miRNA and most commonly results in translational inhibition or
            destabilization of the target mRNA. The RefSeq represents the
            predicted microRNA stem-loop. [provided by RefSeq, Sep 2009].
            
            Sequence Note: This record represents a predicted microRNA
            stem-loop as defined by miRBase. Some sequence at the 5' and 3'
            ends may not be included in the intermediate precursor miRNA
            produced by Drosha cleavage.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript is intronless :: LM608690.1 [ECO:0000345]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-87                AC040173.5         117773-117859       c
FEATURES             Location/Qualifiers
     source          1..87
                     /organism="Homo sapiens"
                     /mol_type="transcribed RNA"
                     /db_xref="taxon:9606"
                     /chromosome="16"
                     /map="16p13.12"
     gene            1..87
                     /gene="MIR365A"
                     /gene_synonym="hsa-mir-365a; mir-365a; MIR365-1;
                     MIRN365-1"
                     /note="microRNA 365a"
                     /db_xref="GeneID:100126355"
                     /db_xref="HGNC:HGNC:33692"
                     /db_xref="MIM:614735"
                     /db_xref="miRBase:MI0000767"
     precursor_RNA   1..87
                     /gene="MIR365A"
                     /gene_synonym="hsa-mir-365a; mir-365a; MIR365-1;
                     MIRN365-1"
                     /product="microRNA 365a"
                     /db_xref="GeneID:100126355"
                     /db_xref="HGNC:HGNC:33692"
                     /db_xref="MIM:614735"
                     /db_xref="miRBase:MI0000767"
     exon            1..87
                     /gene="MIR365A"
                     /gene_synonym="hsa-mir-365a; mir-365a; MIR365-1;
                     MIRN365-1"
                     /inference="alignment:Splign:2.1.0"
     variation       2
                     /gene="MIR365A"
                     /gene_synonym="hsa-mir-365a; mir-365a; MIR365-1;
                     MIRN365-1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:769491915"
     variation       3
                     /gene="MIR365A"
                     /gene_synonym="hsa-mir-365a; mir-365a; MIR365-1;
                     MIRN365-1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:552599676"
     variation       4
                     /gene="MIR365A"
                     /gene_synonym="hsa-mir-365a; mir-365a; MIR365-1;
                     MIRN365-1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1254266472"
     variation       7
                     /gene="MIR365A"
                     /gene_synonym="hsa-mir-365a; mir-365a; MIR365-1;
                     MIRN365-1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1474323844"
     variation       12
                     /gene="MIR365A"
                     /gene_synonym="hsa-mir-365a; mir-365a; MIR365-1;
                     MIRN365-1"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:762310313"
     variation       15
                     /gene="MIR365A"
                     /gene_synonym="hsa-mir-365a; mir-365a; MIR365-1;
                     MIRN365-1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:766076484"
     ncRNA           16..38
                     /ncRNA_class="miRNA"
                     /gene="MIR365A"
                     /gene_synonym="hsa-mir-365a; mir-365a; MIR365-1;
                     MIRN365-1"
                     /product="hsa-miR-365a-5p"
                     /db_xref="miRBase:MIMAT0009199"
                     /db_xref="GeneID:100126355"
                     /db_xref="HGNC:HGNC:33692"
                     /db_xref="MIM:614735"
                     /db_xref="miRBase:MI0000767"
     variation       17
                     /gene="MIR365A"
                     /gene_synonym="hsa-mir-365a; mir-365a; MIR365-1;
                     MIRN365-1"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:773834113"
     variation       20
                     /gene="MIR365A"
                     /gene_synonym="hsa-mir-365a; mir-365a; MIR365-1;
                     MIRN365-1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1567250487"
     variation       21
                     /gene="MIR365A"
                     /gene_synonym="hsa-mir-365a; mir-365a; MIR365-1;
                     MIRN365-1"
                     /replace=""
                     /replace="c"
                     /db_xref="dbSNP:1567250488"
     variation       24
                     /gene="MIR365A"
                     /gene_synonym="hsa-mir-365a; mir-365a; MIR365-1;
                     MIRN365-1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1166908611"
     variation       26
                     /gene="MIR365A"
                     /gene_synonym="hsa-mir-365a; mir-365a; MIR365-1;
                     MIRN365-1"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1396179427"
     variation       30
                     /gene="MIR365A"
                     /gene_synonym="hsa-mir-365a; mir-365a; MIR365-1;
                     MIRN365-1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1368596991"
     variation       34
                     /gene="MIR365A"
                     /gene_synonym="hsa-mir-365a; mir-365a; MIR365-1;
                     MIRN365-1"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1380926089"
     variation       35
                     /gene="MIR365A"
                     /gene_synonym="hsa-mir-365a; mir-365a; MIR365-1;
                     MIRN365-1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2044225672"
     variation       36
                     /gene="MIR365A"
                     /gene_synonym="hsa-mir-365a; mir-365a; MIR365-1;
                     MIRN365-1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1428928383"
     variation       41
                     /gene="MIR365A"
                     /gene_synonym="hsa-mir-365a; mir-365a; MIR365-1;
                     MIRN365-1"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:2044225707"
     variation       43
                     /gene="MIR365A"
                     /gene_synonym="hsa-mir-365a; mir-365a; MIR365-1;
                     MIRN365-1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:759985656"
     variation       44
                     /gene="MIR365A"
                     /gene_synonym="hsa-mir-365a; mir-365a; MIR365-1;
                     MIRN365-1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:767846518"
     variation       45
                     /gene="MIR365A"
                     /gene_synonym="hsa-mir-365a; mir-365a; MIR365-1;
                     MIRN365-1"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:2044225768"
     variation       51
                     /gene="MIR365A"
                     /gene_synonym="hsa-mir-365a; mir-365a; MIR365-1;
                     MIRN365-1"
                     /replace=""
                     /replace="t"
                     /db_xref="dbSNP:2506196548"
     variation       52
                     /gene="MIR365A"
                     /gene_synonym="hsa-mir-365a; mir-365a; MIR365-1;
                     MIRN365-1"
                     /replace="a"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:2506196556"
     variation       53
                     /gene="MIR365A"
                     /gene_synonym="hsa-mir-365a; mir-365a; MIR365-1;
                     MIRN365-1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:912287559"
     variation       54
                     /gene="MIR365A"
                     /gene_synonym="hsa-mir-365a; mir-365a; MIR365-1;
                     MIRN365-1"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:2044225803"
     ncRNA           56..77
                     /ncRNA_class="miRNA"
                     /gene="MIR365A"
                     /gene_synonym="hsa-mir-365a; mir-365a; MIR365-1;
                     MIRN365-1"
                     /product="hsa-miR-365a-3p"
                     /db_xref="miRBase:MIMAT0000710"
                     /db_xref="GeneID:100126355"
                     /db_xref="HGNC:HGNC:33692"
                     /db_xref="MIM:614735"
                     /db_xref="miRBase:MI0000767"
     variation       59
                     /gene="MIR365A"
                     /gene_synonym="hsa-mir-365a; mir-365a; MIR365-1;
                     MIRN365-1"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:2506196569"
     variation       63
                     /gene="MIR365A"
                     /gene_synonym="hsa-mir-365a; mir-365a; MIR365-1;
                     MIRN365-1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:753261308"
     variation       64
                     /gene="MIR365A"
                     /gene_synonym="hsa-mir-365a; mir-365a; MIR365-1;
                     MIRN365-1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1157151100"
     variation       76
                     /gene="MIR365A"
                     /gene_synonym="hsa-mir-365a; mir-365a; MIR365-1;
                     MIRN365-1"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1301772055"
     variation       77
                     /gene="MIR365A"
                     /gene_synonym="hsa-mir-365a; mir-365a; MIR365-1;
                     MIRN365-1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1465901561"
     variation       81
                     /gene="MIR365A"
                     /gene_synonym="hsa-mir-365a; mir-365a; MIR365-1;
                     MIRN365-1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2506196588"
     variation       83
                     /gene="MIR365A"
                     /gene_synonym="hsa-mir-365a; mir-365a; MIR365-1;
                     MIRN365-1"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2044225905"
     variation       84
                     /gene="MIR365A"
                     /gene_synonym="hsa-mir-365a; mir-365a; MIR365-1;
                     MIRN365-1"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1379339808"
ORIGIN      
accgcagggaaaatgagggacttttgggggcagatgtgtttccattccactatcataatgcccctaaaaatccttattgctcttgca
//

by @meso_cacase at DBCLS
This page is licensed under a Creative Commons Attribution 4.0 International License (CC BY 4.0).

If you use GGRNA in your work, please cite:
Naito Y, Bono H. (2012)
GGRNA: an ultrafast, transcript-oriented search engine for genes and transcripts.
Nucleic Acids Res., 40, W592-W596. [Full Text]