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2024-11-01 10:31:30, GGRNA.v2 : RefSeq release 226 (Sep, 2024)

LOCUS       NM_014343               1224 bp    mRNA    linear   PRI 04-AUG-2024
DEFINITION  Homo sapiens claudin 15 (CLDN15), transcript variant 2, mRNA.
ACCESSION   NM_014343
VERSION     NM_014343.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1224)
  AUTHORS   Rajagopal,N. and Nangia,S.
  TITLE     Unique structural features of claudin-5 and claudin-15 lead to
            functionally distinct tight junction strand architecture
  JOURNAL   Ann N Y Acad Sci 1517 (1), 225-233 (2022)
   PUBMED   36114674
  REMARK    GeneRIF: Unique structural features of claudin-5 and claudin-15
            lead to functionally distinct tight junction strand architecture.
REFERENCE   2  (bases 1 to 1224)
  AUTHORS   Hempel,C., Rosenthal,R., Fromm,A., Krug,S.M., Fromm,M., Gunzel,D.
            and Piontek,J.
  TITLE     Tight junction channels claudin-10b and claudin-15: Functional
            mapping of pore-lining residues
  JOURNAL   Ann N Y Acad Sci 1515 (1), 129-142 (2022)
   PUBMED   35650657
  REMARK    GeneRIF: Tight junction channels claudin-10b and claudin-15:
            Functional mapping of pore-lining residues.
REFERENCE   3  (bases 1 to 1224)
  AUTHORS   Watanabe,M., Higashi,T., Ozeki,K., Higashi,A.Y., Sugimoto,K.,
            Mine,H., Takagi,H., Ozaki,Y., Muto,S., Okabe,N., Matsumura,Y.,
            Hasegawa,T., Shio,Y., Suzuki,H. and Chiba,H.
  TITLE     CLDN15 is a novel diagnostic marker for malignant pleural
            mesothelioma
  JOURNAL   Sci Rep 11 (1), 12554 (2021)
   PUBMED   34131154
  REMARK    GeneRIF: CLDN15 is a novel diagnostic marker for malignant pleural
            mesothelioma.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 1224)
  AUTHORS   Zhang,D., Sun,B., Zhao,X., Sun,H., An,J., Lin,X., Zhu,D., Zhao,X.,
            Wang,X., Liu,F., Zhang,Y., Liu,J., Gu,Q., Dong,X., Qiu,Z., Liu,Z.,
            Qi,H., Che,N., Li,J., Cheng,R. and Zheng,X.
  TITLE     Twist1 accelerates tumour vasculogenic mimicry by inhibiting
            Claudin15 expression in triple-negative breast cancer
  JOURNAL   J Cell Mol Med 24 (13), 7163-7174 (2020)
   PUBMED   32469152
  REMARK    GeneRIF: Twist1 accelerates tumour vasculogenic mimicry by
            inhibiting Claudin15 expression in triple-negative breast cancer.
REFERENCE   5  (bases 1 to 1224)
  AUTHORS   Ong,M.L.D.M., Yeruva,S., Sailer,A., Nilsen,S.P. and Turner,J.R.
  TITLE     Differential regulation of claudin-2 and claudin-15 expression in
            children and adults with malabsorptive disease
  JOURNAL   Lab Invest 100 (3), 483-490 (2020)
   PUBMED   31605016
  REMARK    GeneRIF: Differential regulation of claudin-2 and claudin-15
            expression in children and adults with malabsorptive disease.
REFERENCE   6  (bases 1 to 1224)
  AUTHORS   Kiuchi-Saishin,Y., Gotoh,S., Furuse,M., Takasuga,A., Tano,Y. and
            Tsukita,S.
  TITLE     Differential expression patterns of claudins, tight junction
            membrane proteins, in mouse nephron segments
  JOURNAL   J Am Soc Nephrol 13 (4), 875-886 (2002)
   PUBMED   11912246
REFERENCE   7  (bases 1 to 1224)
  AUTHORS   Tsukita,S., Furuse,M. and Itoh,M.
  TITLE     Multifunctional strands in tight junctions
  JOURNAL   Nat Rev Mol Cell Biol 2 (4), 285-293 (2001)
   PUBMED   11283726
  REMARK    Review article
REFERENCE   8  (bases 1 to 1224)
  AUTHORS   Heiskala,M., Peterson,P.A. and Yang,Y.
  TITLE     The roles of claudin superfamily proteins in paracellular transport
  JOURNAL   Traffic 2 (2), 93-98 (2001)
   PUBMED   11247307
  REMARK    Review article
REFERENCE   9  (bases 1 to 1224)
  AUTHORS   Yi,X., Wang,Y. and Yu,F.S.
  TITLE     Corneal epithelial tight junctions and their response to
            lipopolysaccharide challenge
  JOURNAL   Invest Ophthalmol Vis Sci 41 (13), 4093-4100 (2000)
   PUBMED   11095601
REFERENCE   10 (bases 1 to 1224)
  AUTHORS   Kniesel,U. and Wolburg,H.
  TITLE     Tight junctions of the blood-brain barrier
  JOURNAL   Cell Mol Neurobiol 20 (1), 57-76 (2000)
   PUBMED   10690502
  REMARK    Review article
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AJ245738.1 and AK056103.1.
            
            On Jun 2, 2019 this sequence version replaced NM_014343.2.
            
            Summary: This gene encodes a member of the claudin family. Claudins
            are integral membrane proteins and components of tight junction
            strands. Tight junction strands serve as a physical barrier to
            prevent solutes and water from passing freely through the
            paracellular space between epithelial or endothelial cell sheets,
            and also play critical roles in maintaining cell polarity and
            signal transductions. Alternatively spliced transcript variants
            encoding the same protein have been found for this gene. [provided
            by RefSeq, Jun 2010].
            
            Transcript Variant: This variant (2) has a shorter and alternate 5'
            UTR, as compared to variant 1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: ERR279859.229.1, DRR138528.254063.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA2153946, SAMEA2159764
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000308344.10/ ENSP00000308870.5
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-826               AJ245738.1         34-859
            827-1224            AK056103.1         1732-2129
FEATURES             Location/Qualifiers
     source          1..1224
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="7"
                     /map="7q22.1"
     gene            1..1224
                     /gene="CLDN15"
                     /note="claudin 15"
                     /db_xref="GeneID:24146"
                     /db_xref="HGNC:HGNC:2036"
                     /db_xref="MIM:615778"
     exon            1..438
                     /gene="CLDN15"
                     /inference="alignment:Splign:2.1.0"
     variation       2
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1003479289"
     variation       4
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:17135348"
     variation       6
                     /gene="CLDN15"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1350854939"
     variation       7
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1798660908"
     variation       11
                     /gene="CLDN15"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1798660851"
     variation       12
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1798660790"
     variation       17
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:534466198"
     variation       19
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1798660716"
     variation       21
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1798660682"
     variation       24..30
                     /gene="CLDN15"
                     /replace="agaga"
                     /replace="agagaga"
                     /db_xref="dbSNP:778962988"
     variation       24
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1798660643"
     variation       29
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1798660606"
     variation       32
                     /gene="CLDN15"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1023536937"
     variation       34
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:111333670"
     variation       37
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2116842620"
     variation       44
                     /gene="CLDN15"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1798660432"
     variation       47
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:940294447"
     variation       48
                     /gene="CLDN15"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:1798660356"
     variation       49
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1798660304"
     variation       55
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:908500433"
     variation       64
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1798660229"
     variation       65
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:148059973"
     variation       67
                     /gene="CLDN15"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1206760459"
     variation       68
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1352453502"
     variation       71
                     /gene="CLDN15"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:2116842567"
     variation       75
                     /gene="CLDN15"
                     /replace="a"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:952893364"
     variation       76
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:779624611"
     variation       77
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1283240661"
     variation       79
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1798659901"
     variation       80
                     /gene="CLDN15"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1798659868"
     variation       84
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:557880219"
     variation       85
                     /gene="CLDN15"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1798659794"
     variation       89
                     /gene="CLDN15"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1053831393"
     variation       93..106
                     /gene="CLDN15"
                     /replace="gaggctgaggctga"
                     /replace="gaggctgaggctgaggctga"
                     /db_xref="dbSNP:1798659531"
     variation       100
                     /gene="CLDN15"
                     /replace=""
                     /replace="a"
                     /db_xref="dbSNP:1224545620"
     variation       102
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1798659618"
     variation       104
                     /gene="CLDN15"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1584268786"
     variation       108
                     /gene="CLDN15"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1798659494"
     variation       109
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:999528128"
     variation       111
                     /gene="CLDN15"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1584268782"
     variation       112..115
                     /gene="CLDN15"
                     /replace="ccc"
                     /replace="cccc"
                     /db_xref="dbSNP:1798659326"
     variation       112
                     /gene="CLDN15"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:964545766"
     variation       118
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1798659280"
     variation       121
                     /gene="CLDN15"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1254859781"
     variation       124
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2116842491"
     variation       128
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1798659195"
     variation       130
                     /gene="CLDN15"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1584268778"
     variation       131
                     /gene="CLDN15"
                     /replace="a"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:537068057"
     variation       132
                     /gene="CLDN15"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:902543468"
     variation       142
                     /gene="CLDN15"
                     /replace="a"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1018739214"
     variation       143
                     /gene="CLDN15"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:922201795"
     variation       144
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1468751622"
     variation       146
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1158224167"
     variation       147
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:987308831"
     variation       149
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1039286222"
     variation       153
                     /gene="CLDN15"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1798658680"
     variation       155..158
                     /gene="CLDN15"
                     /replace="agtt"
                     /replace="agttagtt"
                     /db_xref="dbSNP:1427018422"
     misc_feature    162..164
                     /gene="CLDN15"
                     /note="upstream in-frame stop codon"
     variation       166
                     /gene="CLDN15"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1798658553"
     variation       167
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1283605415"
     variation       169
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1584268746"
     variation       171
                     /gene="CLDN15"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1285700413"
     variation       172
                     /gene="CLDN15"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:770339306"
     variation       174
                     /gene="CLDN15"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:748484821"
     variation       176
                     /gene="CLDN15"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:549432025"
     variation       179
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1235471762"
     variation       180
                     /gene="CLDN15"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1328907344"
     variation       181
                     /gene="CLDN15"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:771717911"
     variation       182
                     /gene="CLDN15"
                     /replace="a"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:745532582"
     variation       185
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:778760634"
     variation       187
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:756800350"
     variation       188..191
                     /gene="CLDN15"
                     /replace="ggg"
                     /replace="gggg"
                     /db_xref="dbSNP:753285279"
     variation       188
                     /gene="CLDN15"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1798657585"
     variation       189
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:753465488"
     variation       191
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1247974267"
     variation       192
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1798657306"
     variation       194
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:777839895"
     variation       195
                     /gene="CLDN15"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1289463370"
     variation       197
                     /gene="CLDN15"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1798657121"
     variation       198..203
                     /gene="CLDN15"
                     /replace="ccccc"
                     /replace="cccccc"
                     /replace="ccccccc"
                     /db_xref="dbSNP:755492734"
     variation       198
                     /gene="CLDN15"
                     /replace="a"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:569283323"
     variation       199
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:548501878"
     variation       200
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:759422381"
     variation       203
                     /gene="CLDN15"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:751699841"
     variation       204
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1181351825"
     variation       205..207
                     /gene="CLDN15"
                     /replace="gg"
                     /replace="ggg"
                     /db_xref="dbSNP:753430547"
     variation       206
                     /gene="CLDN15"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:763004173"
     variation       209
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:773290672"
     variation       210
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1184694548"
     variation       212
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:536535556"
     variation       213
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:762261215"
     variation       217
                     /gene="CLDN15"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:369387120"
     variation       218
                     /gene="CLDN15"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:201426716"
     variation       219
                     /gene="CLDN15"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1798655652"
     CDS             222..908
                     /gene="CLDN15"
                     /codon_start=1
                     /product="claudin-15"
                     /protein_id="NP_055158.1"
                     /db_xref="CCDS:CCDS5717.1"
                     /db_xref="GeneID:24146"
                     /db_xref="HGNC:HGNC:2036"
                     /db_xref="MIM:615778"
                     /translation="
MSMAVETFGFFMATVGLLMLGVTLPNSYWRVSTVHGNVITTNTIFENLWFSCATDSLGVYNCWEFPSMLALSGYIQACRALMITAILLGFLGLLLGIAGLRCTNIGGLELSRKAKLAATAGALHILAGICGMVAISWYAFNITRDFFDPLYPGTKYELGPALYLGWSASLISILGGLCLCSACCCGSDEDPAASARRPYQAPVSVMPVATSDQEGDSSFGKYGRNAYV"
     misc_feature    225..293
                     /gene="CLDN15"
                     /note="propagated from UniProtKB/Swiss-Prot (P56746.1);
                     transmembrane region"
     misc_feature    228..752
                     /gene="CLDN15"
                     /note="PMP-22/EMP/MP20/Claudin family; Region:
                     PMP22_Claudin; cl21598"
                     /db_xref="CDD:473919"
     misc_feature    384..386
                     /gene="CLDN15"
                     /note="Important for Na(+)-selective paracellular ion
                     transport. /evidence=ECO:0000269|PubMed:12055082,
                     ECO:0000269|PubMed:35650657; propagated from
                     UniProtKB/Swiss-Prot (P56746.1); other site"
     misc_feature    411..413
                     /gene="CLDN15"
                     /note="Important for Na(+)-selective paracellular ion
                     transport. /evidence=ECO:0000269|PubMed:12055082,
                     ECO:0000269|PubMed:35650657; propagated from
                     UniProtKB/Swiss-Prot (P56746.1); other site"
     misc_feature    423..425
                     /gene="CLDN15"
                     /note="Important for the formation of tight-junction
                     strand-like structures. /evidence=ECO:0000250; propagated
                     from UniProtKB/Swiss-Prot (P56746.1); other site"
     misc_feature    444..518
                     /gene="CLDN15"
                     /note="propagated from UniProtKB/Swiss-Prot (P56746.1);
                     transmembrane region"
     misc_feature    552..554
                     /gene="CLDN15"
                     /note="Phosphoserine.
                     /evidence=ECO:0007744|PubMed:19690332; propagated from
                     UniProtKB/Swiss-Prot (P56746.1); phosphorylation site"
     misc_feature    567..641
                     /gene="CLDN15"
                     /note="propagated from UniProtKB/Swiss-Prot (P56746.1);
                     transmembrane region"
     misc_feature    657..662
                     /gene="CLDN15"
                     /note="propagated from UniProtKB/Swiss-Prot (P56746.1);
                     Region: Important for the formation of tight-junction
                     strand-like structures. /evidence=ECO:0000250"
     misc_feature    699..767
                     /gene="CLDN15"
                     /note="propagated from UniProtKB/Swiss-Prot (P56746.1);
                     transmembrane region"
     misc_feature    843..905
                     /gene="CLDN15"
                     /note="propagated from UniProtKB/Swiss-Prot (P56746.1);
                     Region: Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite"
     misc_feature    852..854
                     /gene="CLDN15"
                     /note="Phosphoserine.
                     /evidence=ECO:0000250|UniProtKB:D3ZQJ0; propagated from
                     UniProtKB/Swiss-Prot (P56746.1); phosphorylation site"
     misc_feature    873..875
                     /gene="CLDN15"
                     /note="Phosphoserine.
                     /evidence=ECO:0000250|UniProtKB:Q9Z0S5; propagated from
                     UniProtKB/Swiss-Prot (P56746.1); phosphorylation site"
     variation       226
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1350459358"
     variation       227
                     /gene="CLDN15"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1272885657"
     variation       229
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:768884335"
     variation       233
                     /gene="CLDN15"
                     /replace="a"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:745557741"
     variation       234
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1798655150"
     variation       235
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:372492489"
     variation       240
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:770765894"
     variation       241
                     /gene="CLDN15"
                     /replace="a"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:369730209"
     variation       246
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1313688853"
     variation       250
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:777429148"
     variation       251
                     /gene="CLDN15"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1584268634"
     variation       255
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1798654482"
     variation       257
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:756027819"
     variation       258
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:748011705"
     variation       261
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2116842196"
     variation       263
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2116842192"
     variation       265
                     /gene="CLDN15"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1410327936"
     variation       269
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:781229200"
     variation       270
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:754724692"
     variation       272
                     /gene="CLDN15"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:751410119"
     variation       275
                     /gene="CLDN15"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1798653844"
     variation       276
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1417997508"
     variation       283
                     /gene="CLDN15"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:766527466"
     variation       284
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1798653602"
     variation       285
                     /gene="CLDN15"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:144226303"
     variation       286
                     /gene="CLDN15"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1250638805"
     variation       289..292
                     /gene="CLDN15"
                     /replace="ct"
                     /replace="ctct"
                     /db_xref="dbSNP:1012108761"
     variation       289
                     /gene="CLDN15"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1204807311"
     variation       291
                     /gene="CLDN15"
                     /replace="a"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:940237751"
     variation       292
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:750460193"
     variation       296
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:765325744"
     variation       300
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1048856874"
     variation       304
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:762005185"
     variation       309
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1293931985"
     variation       310
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:776976484"
     variation       312
                     /gene="CLDN15"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1195346258"
     variation       313
                     /gene="CLDN15"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1584268556"
     variation       320
                     /gene="CLDN15"
                     /replace="a"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:764733795"
     variation       323
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1279559194"
     variation       324
                     /gene="CLDN15"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:760934332"
     variation       326
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:931369449"
     variation       327
                     /gene="CLDN15"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:776010967"
     variation       329
                     /gene="CLDN15"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1202036157"
     variation       332
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:957872054"
     variation       333
                     /gene="CLDN15"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:770642981"
     variation       339
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:748981078"
     variation       344
                     /gene="CLDN15"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:773046017"
     variation       346
                     /gene="CLDN15"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:769154207"
     variation       347
                     /gene="CLDN15"
                     /replace="a"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:200093665"
     variation       350
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1798650282"
     variation       351
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:747760494"
     variation       356
                     /gene="CLDN15"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:754951698"
     variation       357
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:746737426"
     variation       365
                     /gene="CLDN15"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:539601708"
     variation       369
                     /gene="CLDN15"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1562905689"
     variation       374
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1219867542"
     variation       375
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1451478694"
     variation       376
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1274357098"
     variation       379
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:758572886"
     variation       382
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1327233728"
     variation       383
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1267714270"
     variation       384
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:750625230"
     variation       386
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:201176000"
     variation       390
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:757283362"
     variation       395
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:372695231"
     variation       396
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:764451471"
     variation       398
                     /gene="CLDN15"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:761250886"
     variation       399
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1798649319"
     variation       403
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:775959487"
     variation       411
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1387338341"
     variation       413
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1159343024"
     variation       416..418
                     /gene="CLDN15"
                     /replace="ccc"
                     /replace="cccc"
                     /db_xref="dbSNP:35907449"
     variation       417
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:767969661"
     variation       418
                     /gene="CLDN15"
                     /replace="a"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:760017086"
     variation       419..420
                     /gene="CLDN15"
                     /replace="gt"
                     /replace="gtgt"
                     /db_xref="dbSNP:765921171"
     variation       419
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:367748230"
     variation       420
                     /gene="CLDN15"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:1454161274"
     variation       423
                     /gene="CLDN15"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:1196104449"
     variation       426
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:769543993"
     variation       430
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1241550781"
     variation       431
                     /gene="CLDN15"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1798648511"
     variation       433
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1798648457"
     exon            439..603
                     /gene="CLDN15"
                     /inference="alignment:Splign:2.1.0"
     variation       440
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1798586451"
     variation       443
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1164570867"
     variation       445
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1442230652"
     variation       451
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1373850198"
     variation       455..456
                     /gene="CLDN15"
                     /replace="cc"
                     /replace="ccc"
                     /db_xref="dbSNP:1798586153"
     variation       456
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1401559522"
     variation       457
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:763488001"
     variation       459
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:540477759"
     variation       461
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1798585934"
     variation       462
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:573348730"
     variation       464
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:749101945"
     variation       471
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1385938082"
     variation       473
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:773466668"
     variation       474
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:765578247"
     variation       480
                     /gene="CLDN15"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:748167511"
     variation       486
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1798585554"
     variation       487
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:781452464"
     variation       488
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1798585449"
     variation       489
                     /gene="CLDN15"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:1390265079"
     variation       492
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:755492680"
     variation       494
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:945301173"
     variation       495
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:747527920"
     variation       497
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:149596550"
     variation       498
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:758786700"
     variation       503
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:750811957"
     variation       504
                     /gene="CLDN15"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1485158356"
     variation       507
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:138215552"
     variation       508
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:755772958"
     variation       510
                     /gene="CLDN15"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1350595796"
     variation       511
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2116836989"
     variation       514
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:752167334"
     variation       515
                     /gene="CLDN15"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:575269196"
     variation       516
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1201066988"
     variation       522
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1327154370"
     variation       523
                     /gene="CLDN15"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:759019587"
     variation       527
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1798584457"
     variation       529
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1413124049"
     variation       532
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2116836958"
     variation       534
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:774339593"
     variation       535
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:146377590"
     variation       536
                     /gene="CLDN15"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1436360930"
     variation       539
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:762748647"
     variation       541
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1187590060"
     variation       542
                     /gene="CLDN15"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:371309936"
     variation       544
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:867619194"
     variation       545
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1475437667"
     variation       549
                     /gene="CLDN15"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1798583953"
     variation       550
                     /gene="CLDN15"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1798583894"
     variation       551
                     /gene="CLDN15"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:770101439"
     variation       553
                     /gene="CLDN15"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1184805508"
     variation       555
                     /gene="CLDN15"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:142152850"
     variation       556
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:201480405"
     variation       560
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1467010937"
     variation       562
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1212033462"
     variation       565
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1486890021"
     variation       570
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1271478788"
     variation       571
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:80277788"
     variation       572
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:138919994"
     variation       573
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1271958399"
     variation       576
                     /gene="CLDN15"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1584266612"
     variation       578
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:200441148"
     variation       579
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:374570698"
     variation       583
                     /gene="CLDN15"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1584266596"
     variation       585
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:755717983"
     variation       586
                     /gene="CLDN15"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1416380516"
     variation       588
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1352583962"
     variation       589
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1327968506"
     variation       590
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1161703940"
     variation       593
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2116836792"
     variation       594
                     /gene="CLDN15"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:752327023"
     variation       599
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:767200047"
     variation       600
                     /gene="CLDN15"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:754495167"
     variation       601
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:867510300"
     variation       602
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:145175005"
     exon            604..685
                     /gene="CLDN15"
                     /inference="alignment:Splign:2.1.0"
     variation       606
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:887406683"
     variation       607
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:373959567"
     variation       608
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1798530740"
     variation       614
                     /gene="CLDN15"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1187568163"
     variation       618
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1475396580"
     variation       620
                     /gene="CLDN15"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:753646317"
     variation       621
                     /gene="CLDN15"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:763821487"
     variation       623
                     /gene="CLDN15"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1798530364"
     variation       625
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1798530306"
     variation       626
                     /gene="CLDN15"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:996301584"
     variation       630
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1798530218"
     variation       632
                     /gene="CLDN15"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1798530175"
     variation       635
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:755988993"
     variation       640
                     /gene="CLDN15"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:752834773"
     variation       643
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:767849586"
     variation       650
                     /gene="CLDN15"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1332094437"
     variation       651
                     /gene="CLDN15"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:2116834247"
     variation       652
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2116834245"
     variation       658
                     /gene="CLDN15"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:141080465"
     variation       662
                     /gene="CLDN15"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1798529900"
     variation       665
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1233479984"
     variation       667
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1323167335"
     variation       669..672
                     /gene="CLDN15"
                     /replace="t"
                     /replace="ttgt"
                     /db_xref="dbSNP:1373243400"
     variation       669
                     /gene="CLDN15"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:1315206886"
     variation       670
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:774415158"
     variation       674
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1299303399"
     variation       675
                     /gene="CLDN15"
                     /replace="a"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1040938530"
     variation       676
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:944925162"
     variation       682
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:766828072"
     variation       685
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1798529090"
     exon            686..802
                     /gene="CLDN15"
                     /inference="alignment:Splign:2.1.0"
     variation       687
                     /gene="CLDN15"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1453368342"
     variation       693
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:758393097"
     variation       695
                     /gene="CLDN15"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:750529539"
     variation       699
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:765597358"
     variation       700
                     /gene="CLDN15"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1196277215"
     variation       701
                     /gene="CLDN15"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1484921253"
     variation       702
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:754103171"
     variation       703
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1201486777"
     variation       704
                     /gene="CLDN15"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1348277654"
     variation       707
                     /gene="CLDN15"
                     /replace="a"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1347778906"
     variation       708
                     /gene="CLDN15"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:1798525748"
     variation       709
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1798525708"
     variation       710
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1249629796"
     variation       714
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1226790026"
     variation       715
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1341358254"
     variation       716
                     /gene="CLDN15"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:764532136"
     variation       720
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1412677434"
     variation       721
                     /gene="CLDN15"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:761164428"
     variation       725
                     /gene="CLDN15"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:774145838"
     variation       727
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1242607413"
     variation       730
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1416055356"
     variation       733
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:948036654"
     variation       734
                     /gene="CLDN15"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:915517375"
     variation       739
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:770767794"
     variation       740
                     /gene="CLDN15"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:762314602"
     variation       741
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1798525068"
     variation       743..745
                     /gene="CLDN15"
                     /replace="gg"
                     /replace="ggg"
                     /db_xref="dbSNP:2116833747"
     variation       750
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:372104568"
     variation       752
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:769567364"
     variation       754
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1482852344"
     variation       756
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:369708189"
     variation       758
                     /gene="CLDN15"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:546571567"
     variation       760
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:768435109"
     variation       763
                     /gene="CLDN15"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:746864332"
     variation       764..777
                     /gene="CLDN15"
                     /replace="cg"
                     /replace="cgcctgctgctgcg"
                     /db_xref="dbSNP:1798524312"
     variation       764
                     /gene="CLDN15"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:780189931"
     variation       766
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1195291469"
     variation       767
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1318756086"
     variation       769
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1260203029"
     variation       770
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1231647165"
     variation       772
                     /gene="CLDN15"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:924093320"
     variation       776
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:528027533"
     variation       777
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:750431296"
     variation       778
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1333890712"
     variation       783
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1027266090"
     variation       785
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1446838798"
     variation       786
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:779074661"
     variation       787
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:571133331"
     variation       788
                     /gene="CLDN15"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:757331029"
     variation       789
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:754369433"
     variation       791
                     /gene="CLDN15"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1798523939"
     variation       792
                     /gene="CLDN15"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:202239413"
     variation       793
                     /gene="CLDN15"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:900240262"
     variation       794
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:761110853"
     variation       795
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1362543485"
     variation       797
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:753128708"
     variation       798
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1458632195"
     variation       800
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:766085881"
     variation       801
                     /gene="CLDN15"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:762687305"
     variation       802
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1468155063"
     exon            803..1224
                     /gene="CLDN15"
                     /inference="alignment:Splign:2.1.0"
     variation       807
                     /gene="CLDN15"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:948783117"
     variation       808
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1194098100"
     variation       809
                     /gene="CLDN15"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1489177557"
     variation       810
                     /gene="CLDN15"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1798520927"
     variation       811
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:541427413"
     variation       812
                     /gene="CLDN15"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1209289696"
     variation       813
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1312726703"
     variation       814
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:771073693"
     variation       816
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:749316714"
     variation       817
                     /gene="CLDN15"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1360836460"
     variation       818
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:370403774"
     variation       819
                     /gene="CLDN15"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1400956565"
     variation       820
                     /gene="CLDN15"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1342721471"
     variation       825
                     /gene="CLDN15"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1311463759"
     variation       826..827
                     /gene="CLDN15"
                     /replace=""
                     /replace="ca"
                     /db_xref="dbSNP:1245647296"
     variation       827
                     /gene="CLDN15"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1047319"
     variation       829
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:149925321"
     variation       835
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1178318178"
     variation       836
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1408338123"
     variation       839
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:143443191"
     variation       842
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:200846307"
     variation       843
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1478943283"
     variation       846
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:764876755"
     variation       850
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1798519811"
     variation       851
                     /gene="CLDN15"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:756934010"
     variation       852
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1798519706"
     variation       853
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1798519649"
     variation       854
                     /gene="CLDN15"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:148860794"
     variation       856
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1798519508"
     variation       857
                     /gene="CLDN15"
                     /replace="a"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:753297720"
     variation       858
                     /gene="CLDN15"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:535594270"
     variation       859..864
                     /gene="CLDN15"
                     /replace="aag"
                     /replace="aagaag"
                     /db_xref="dbSNP:1364234328"
     variation       860
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:760220419"
     variation       862
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:775494720"
     variation       863
                     /gene="CLDN15"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:767416076"
     variation       864
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:759319996"
     variation       865
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:774025874"
     variation       866
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1458720746"
     variation       867
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:147800282"
     variation       869
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1395877401"
     variation       870
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1380510012"
     variation       871
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1305160943"
     variation       872
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1798518602"
     variation       876
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1798518559"
     variation       880
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:771242076"
     variation       884
                     /gene="CLDN15"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:749495146"
     variation       886
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1372324195"
     variation       887
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1332153924"
     variation       888
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1467327363"
     variation       889
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:867185152"
     variation       890
                     /gene="CLDN15"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:773604464"
     variation       893
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1798518188"
     variation       896
                     /gene="CLDN15"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:769987971"
     variation       898
                     /gene="CLDN15"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:781681270"
     variation       899
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1175366935"
     variation       901
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:769045851"
     variation       905
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2116833081"
     variation       909
                     /gene="CLDN15"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:747358908"
     variation       912..936
                     /gene="CLDN15"
                     /replace="ct"
                     /replace="ctctggcccgtgggccccgctgtct"
                     /db_xref="dbSNP:1293212799"
     variation       914
                     /gene="CLDN15"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1199986572"
     variation       915
                     /gene="CLDN15"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:780304067"
     variation       916
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1268014668"
     variation       917
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1336109338"
     variation       918
                     /gene="CLDN15"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:983279052"
     variation       920
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:951947613"
     variation       921
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:183990374"
     variation       923
                     /gene="CLDN15"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1315308847"
     variation       924
                     /gene="CLDN15"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1238548549"
     variation       928
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1584265022"
     variation       930
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:552753746"
     variation       931
                     /gene="CLDN15"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:964368649"
     variation       932
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1449180542"
     variation       935
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1392542426"
     variation       937
                     /gene="CLDN15"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:1798517351"
     variation       938..948
                     /gene="CLDN15"
                     /replace="cccactgcccc"
                     /replace="cccactgcccccccactgcccc"
                     /db_xref="dbSNP:1798517137"
     variation       938
                     /gene="CLDN15"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1458195944"
     variation       940
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1351349907"
     variation       941
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:777470398"
     variation       942..974
                     /gene="CLDN15"
                     /replace="c"
                     /replace="ctgccccaaggagaggggacctggccggggccc"
                     /db_xref="dbSNP:1408321043"
     variation       943
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:534629383"
     variation       945
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:752164679"
     variation       949
                     /gene="CLDN15"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1584264993"
     variation       951
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1156722195"
     variation       952
                     /gene="CLDN15"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1179955196"
     variation       955
                     /gene="CLDN15"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:767426125"
     variation       956
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1798516937"
     variation       958
                     /gene="CLDN15"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1166995174"
     variation       959
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1472760194"
     variation       960
                     /gene="CLDN15"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:1348251488"
     variation       961
                     /gene="CLDN15"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1798516794"
     variation       962
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1798516762"
     variation       965
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:570330669"
     variation       968..971
                     /gene="CLDN15"
                     /replace="ggg"
                     /replace="gggg"
                     /replace="ggggg"
                     /db_xref="dbSNP:1298917555"
     variation       968
                     /gene="CLDN15"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:922380967"
     variation       972
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:879487318"
     variation       973
                     /gene="CLDN15"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1416625745"
     variation       976
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1584264964"
     variation       979
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1798516472"
     variation       981
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1798516434"
     variation       989
                     /gene="CLDN15"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1584264957"
     variation       990
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1798516264"
     variation       991
                     /gene="CLDN15"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1798516215"
     variation       994
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1798516163"
     variation       995
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1798516109"
     variation       996
                     /gene="CLDN15"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1019042841"
     variation       997
                     /gene="CLDN15"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1798515991"
     variation       998..1001
                     /gene="CLDN15"
                     /replace="g"
                     /replace="gccg"
                     /db_xref="dbSNP:1168028090"
     variation       999..1037
                     /gene="CLDN15"
                     /replace="ccggccacg"
                     /replace="ccggccacgccccgctcccgtagccccgccccggccacg"
                     /db_xref="dbSNP:1584264929"
     variation       999
                     /gene="CLDN15"
                     /replace="a"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1433493453"
     variation       1004
                     /gene="CLDN15"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:942365372"
     variation       1005
                     /gene="CLDN15"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1249987966"
     variation       1006..1031
                     /gene="CLDN15"
                     /replace="cgccccg"
                     /replace="cgccccgctcccgtagccccgccccg"
                     /replace="cgccccgctcccgtagccccgccccgctcccgtagccccgccccg"
                     /db_xref="dbSNP:1798514973"
     variation       1006
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1008618215"
     variation       1007..1027
                     /gene="CLDN15"
                     /replace="gccccgc"
                     /replace="gccccgctcccgtagccccgc"
                     /db_xref="dbSNP:910502667"
     variation       1008
                     /gene="CLDN15"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1798515515"
     variation       1010
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:955801974"
     variation       1011
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1483058870"
     variation       1012
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1031824590"
     variation       1015
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1798515254"
     variation       1016
                     /gene="CLDN15"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1798515192"
     variation       1018
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1798515138"
     variation       1021
                     /gene="CLDN15"
                     /replace=""
                     /replace="g"
                     /db_xref="dbSNP:1025495453"
     variation       1027
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1483840381"
     variation       1028..1041
                     /gene="CLDN15"
                     /replace="ccc"
                     /replace="cccggccacggccc"
                     /db_xref="dbSNP:1169311912"
     variation       1031
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:552485066"
     variation       1032
                     /gene="CLDN15"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1250887953"
     variation       1033
                     /gene="CLDN15"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1183581283"
     variation       1035
                     /gene="CLDN15"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1442928559"
     variation       1039
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1798513809"
     variation       1042
                     /gene="CLDN15"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:17135342"
     variation       1043
                     /gene="CLDN15"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1376482784"
     variation       1044
                     /gene="CLDN15"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:760242770"
     variation       1052
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1013589469"
     variation       1053..1057
                     /gene="CLDN15"
                     /replace="ctc"
                     /replace="ctctc"
                     /db_xref="dbSNP:1562902893"
     variation       1053
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2116832754"
     variation       1056
                     /gene="CLDN15"
                     /replace="t"
                     /replace="tt"
                     /db_xref="dbSNP:200275514"
     variation       1057
                     /gene="CLDN15"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1379122389"
     variation       1058
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:537338019"
     variation       1061
                     /gene="CLDN15"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1798513011"
     variation       1062
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1798512956"
     variation       1064
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:772613666"
     variation       1065
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1798512823"
     variation       1072
                     /gene="CLDN15"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:2116832711"
     variation       1074..1078
                     /gene="CLDN15"
                     /replace="aa"
                     /replace="aagaa"
                     /db_xref="dbSNP:1273624980"
     variation       1082
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1798512706"
     variation       1088
                     /gene="CLDN15"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1442741647"
     variation       1089
                     /gene="CLDN15"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1798512564"
     variation       1092
                     /gene="CLDN15"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1212016438"
     variation       1095
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1798512439"
     variation       1097
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:940098349"
     variation       1101
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1235603876"
     variation       1103
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1472436184"
     variation       1104
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1798512236"
     variation       1106
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1189278132"
     variation       1108
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1392169778"
     variation       1109
                     /gene="CLDN15"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:1798512100"
     variation       1113
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1798512043"
     variation       1116
                     /gene="CLDN15"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:908659321"
     variation       1117
                     /gene="CLDN15"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1047545030"
     variation       1119
                     /gene="CLDN15"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1798511831"
     variation       1119
                     /gene="CLDN15"
                     /replace="t"
                     /replace="tt"
                     /db_xref="dbSNP:1798511879"
     variation       1120
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1227362969"
     variation       1121
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1376568505"
     variation       1124
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:546609333"
     variation       1127
                     /gene="CLDN15"
                     /replace="a"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:548376323"
     variation       1128
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1798511471"
     variation       1135
                     /gene="CLDN15"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:920424303"
     variation       1136
                     /gene="CLDN15"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1798511325"
     variation       1138
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1584264875"
     variation       1140
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1360127765"
     variation       1145
                     /gene="CLDN15"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:902807356"
     variation       1146
                     /gene="CLDN15"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1052009916"
     variation       1150
                     /gene="CLDN15"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1798511015"
     variation       1151
                     /gene="CLDN15"
                     /replace=""
                     /replace="t"
                     /db_xref="dbSNP:1798510959"
     variation       1161
                     /gene="CLDN15"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:974662860"
     variation       1162
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1798510812"
     variation       1163
                     /gene="CLDN15"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1584264851"
     variation       1170
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:900633686"
     variation       1171
                     /gene="CLDN15"
                     /replace="a"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:964998926"
     variation       1172
                     /gene="CLDN15"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:1296368825"
     variation       1173
                     /gene="CLDN15"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1428421786"
     variation       1174
                     /gene="CLDN15"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1798510560"
     variation       1177
                     /gene="CLDN15"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1345292617"
     variation       1180
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1220686576"
     variation       1184
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1584264839"
     variation       1185
                     /gene="CLDN15"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:2116832555"
     variation       1187..1208
                     /gene="CLDN15"
                     /replace="ataaat"
                     /replace="ataaatacattcattaataaat"
                     /db_xref="dbSNP:1798510204"
     variation       1187
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1392051154"
     variation       1193
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:190503458"
     regulatory      1202..1207
                     /regulatory_class="polyA_signal_sequence"
                     /gene="CLDN15"
                     /note="hexamer: AATAAA"
     variation       1202
                     /gene="CLDN15"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1276311206"
     variation       1203
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:559810959"
     variation       1205
                     /gene="CLDN15"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:547542782"
     variation       1206
                     /gene="CLDN15"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:1423429231"
     variation       1208
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1411977054"
     variation       1212
                     /gene="CLDN15"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1249951525"
     variation       1212
                     /gene="CLDN15"
                     /replace="t"
                     /replace="tt"
                     /db_xref="dbSNP:1463559693"
     variation       1222
                     /gene="CLDN15"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1798510034"
     polyA_site      1224
                     /gene="CLDN15"
                     /note="major polyA site"
ORIGIN      
attcctctgacctgccaggaagcagagagacccacagagcaggagggaggcagaaagtggagacggacctgagcccgaggaagaggcaggcagaggctgaggctgattccaccccagcctgcctggacaaccctccttagccgcagccccttccagttccctaggggttctgcccctccccctctctggggcaccagccccccagggtcctgcatcccaccatgtcgatggctgtggaaacctttggcttcttcatggcaactgtggggctgctgatgctgggggtgactctgccaaacagctactggcgagtgtccactgtgcacgggaacgtcatcaccaccaacaccatcttcgagaacctctggtttagctgtgccaccgactccctgggcgtctacaactgctgggagttcccgtccatgctggccctctctgggtatattcaggcctgccgggcactcatgatcaccgccatcctcctgggcttcctcggcctcttgctaggcatagcgggcctgcgctgcaccaacattgggggcctggagctctccaggaaagccaagctggcggccaccgcaggggccctccacattctggccggtatctgcgggatggtggccatctcctggtacgccttcaacatcacccgggacttcttcgaccccttgtaccccggaaccaagtacgagctgggccccgccctctacctggggtggagcgcctcactgatctccatcctgggtggcctctgcctctgctccgcctgctgctgcggctctgacgaggacccagccgccagcgcccggcggccctaccaggctccagtgtccgtgatgcccgtcgccacctcggaccaagaaggcgacagcagctttggcaaatacggcagaaacgcctacgtgtagcagctctggcccgtgggccccgctgtcttcccactgccccaaggagaggggacctggccggggcccattcccctatagtaacctcaggggccggccacgccccgctcccgtagccccgccccggccacggccccgtgtcttgcactctcatggcccctccaggccaagaactgctcttgggaagtcgcatatctcccctctgaggctggatccctcatcttctgaccctgggttctgggctgtgaaggggacggtgtccccgcacgtttgtattgtgtataaatacattcattaataaatgcatattgtgaccgtt
//

by @meso_cacase at DBCLS
This page is licensed under a Creative Commons Attribution 4.0 International License (CC BY 4.0).

If you use GGRNA in your work, please cite:
Naito Y, Bono H. (2012)
GGRNA: an ultrafast, transcript-oriented search engine for genes and transcripts.
Nucleic Acids Res., 40, W592-W596. [Full Text]