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2024-11-01 10:25:15, GGRNA.v2 : RefSeq release 226 (Sep, 2024)

LOCUS       NM_001171095            2921 bp    mRNA    linear   PRI 05-AUG-2024
DEFINITION  Homo sapiens claudin 2 (CLDN2), transcript variant 3, mRNA.
ACCESSION   NM_001171095
VERSION     NM_001171095.2
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2921)
  AUTHORS   Eguchi,H., Yu,Y., Yoshino,Y., Hara,H., Tanaka,H. and Ikari,A.
  TITLE     Plasma-activated medium ameliorates the chemoresistance of human
            lung adenocarcinoma cells mediated via downregulation of claudin-2
            expression
  JOURNAL   Arch Biochem Biophys 751, 109846 (2024)
   PUBMED   38056686
  REMARK    GeneRIF: Plasma-activated medium ameliorates the chemoresistance of
            human lung adenocarcinoma cells mediated via downregulation of
            claudin-2 expression.
REFERENCE   2  (bases 1 to 2921)
  AUTHORS   Telgenhoff,D.
  TITLE     Claudin-2 in hyperproliferative migrating keratinocytes and
            migration inhibition via siRNA knockdown
  JOURNAL   Anat Histol Embryol 52 (5), 723-731 (2023)
   PUBMED   37147871
  REMARK    GeneRIF: Claudin-2 in hyperproliferative migrating keratinocytes
            and migration inhibition via siRNA knockdown.
REFERENCE   3  (bases 1 to 2921)
  AUTHORS   Arai,W., Konno,T., Kohno,T., Kodera,Y., Tsujiwaki,M., Shindo,Y.,
            Chiba,H., Miyajima,M., Sakuma,Y., Watanabe,A. and Kojima,T.
  TITLE     Downregulation of angulin-1/LSR induces malignancy via upregulation
            of EGF-dependent claudin-2 and TGF-beta-dependent cell metabolism
            in human lung adenocarcinoma A549 cells
  JOURNAL   Oncotarget 14, 261-275 (2023)
   PUBMED   36961882
  REMARK    GeneRIF: Downregulation of angulin-1/LSR induces malignancy via
            upregulation of EGF-dependent claudin-2 and TGF-beta-dependent cell
            metabolism in human lung adenocarcinoma A549 cells.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 2921)
  AUTHORS   Koumangoye,R., Penny,P. and Delpire,E.
  TITLE     Loss of NKCC1 function increases epithelial tight junction
            permeability by upregulating claudin-2 expression
  JOURNAL   Am J Physiol Cell Physiol 323 (4), C1251-C1263 (2022)
   PUBMED   35968893
  REMARK    GeneRIF: Loss of NKCC1 function increases epithelial tight junction
            permeability by upregulating claudin-2 expression.
REFERENCE   5  (bases 1 to 2921)
  AUTHORS   Kinugasa,T., Tsunoda,T., Mizoguchi,E., Okada,T., Sudo,T.,
            Kawahara,A., Akiba,J. and Akagi,Y.
  TITLE     Chitinase 3-like 1, Carcinoembryonic Antigen-related Cell Adhesion
            Molecule 6, and Ectopic Claudin-2 in the Carcinogenic Processes of
            Ulcerative Colitis
  JOURNAL   Anticancer Res 42 (8), 4119-4127 (2022)
   PUBMED   35896264
  REMARK    GeneRIF: Chitinase 3-like 1, Carcinoembryonic Antigen-related Cell
            Adhesion Molecule 6, and Ectopic Claudin-2 in the Carcinogenic
            Processes of Ulcerative Colitis.
REFERENCE   6  (bases 1 to 2921)
  AUTHORS   Kniesel,U. and Wolburg,H.
  TITLE     Tight junctions of the blood-brain barrier
  JOURNAL   Cell Mol Neurobiol 20 (1), 57-76 (2000)
   PUBMED   10690502
  REMARK    Review article
REFERENCE   7  (bases 1 to 2921)
  AUTHORS   Itoh,M., Furuse,M., Morita,K., Kubota,K., Saitou,M. and Tsukita,S.
  TITLE     Direct binding of three tight junction-associated MAGUKs, ZO-1,
            ZO-2, and ZO-3, with the COOH termini of claudins
  JOURNAL   J Cell Biol 147 (6), 1351-1363 (1999)
   PUBMED   10601346
REFERENCE   8  (bases 1 to 2921)
  AUTHORS   Morita,K., Furuse,M., Fujimoto,K. and Tsukita,S.
  TITLE     Claudin multigene family encoding four-transmembrane domain protein
            components of tight junction strands
  JOURNAL   Proc Natl Acad Sci U S A 96 (2), 511-516 (1999)
   PUBMED   9892664
REFERENCE   9  (bases 1 to 2921)
  AUTHORS   Furuse,M., Fujita,K., Hiiragi,T., Fujimoto,K. and Tsukita,S.
  TITLE     Claudin-1 and -2: novel integral membrane proteins localizing at
            tight junctions with no sequence similarity to occludin
  JOURNAL   J Cell Biol 141 (7), 1539-1550 (1998)
   PUBMED   9647647
REFERENCE   10 (bases 1 to 2921)
  AUTHORS   Shelton,C., LaRusch,J. and Whitcomb,D.C.
  TITLE     Pancreatitis Overview
  JOURNAL   (in) Adam MP, Feldman J, Mirzaa GM, Pagon RA, Wallace SE, Bean LJH,
            Gripp KW and Amemiya A (Eds.);
            GENEREVIEWS(R);
            (1993)
   PUBMED   24624459
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AK312515.1, AK075405.1 and
            AA973123.1.
            
            On Aug 13, 2020 this sequence version replaced NM_001171095.1.
            
            Summary: This gene product belongs to the claudin protein family
            whose members have been identified as major integral membrane
            proteins localized exclusively at tight junctions. Claudins are
            expressed in an organ-specific manner and regulate tissue-specific
            physiologic properties of tight junctions. This protein is
            expressed in the intestine. Alternatively spliced transcript
            variants with different 5' untranslated region have been found for
            this gene.[provided by RefSeq, Jan 2010].
            
            Transcript Variant: This variant (3) uses an alternate 5'
            non-coding exon compared to variant 1. Variants 1-3 encode the same
            protein.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK312515.1, DA396340.1 [ECO:0000332]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-981               AK312515.1         1-981
            982-2484            AK075405.1         1020-2522
            2485-2921           AA973123.1         12-448              c
FEATURES             Location/Qualifiers
     source          1..2921
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="X"
                     /map="Xq22.3"
     gene            1..2921
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /note="claudin 2"
                     /db_xref="GeneID:9075"
                     /db_xref="HGNC:HGNC:2041"
                     /db_xref="MIM:300520"
     exon            1..110
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /inference="alignment:Splign:2.1.0"
     variation       1..20
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="ag"
                     /replace="aggcatggctgcccttttag"
                     /db_xref="dbSNP:1284780456"
     variation       4
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933343122"
     variation       7
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1339806291"
     variation       9
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2054095563"
     variation       12
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1232357558"
     variation       16
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:1182707026"
     variation       18
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1440025649"
     variation       20
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1399475185"
     variation       21
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1933343435"
     variation       22
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:191327348"
     variation       40
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:1933343566"
     variation       41
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:781579044"
     variation       46
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1933343674"
     variation       48
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2147791310"
     variation       50
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933343735"
     variation       52
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1933343803"
     variation       53
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1933343852"
     variation       55
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:941233929"
     variation       57
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:748173436"
     variation       64
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1933344013"
     variation       66
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:967941023"
     variation       69
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1933344122"
     variation       71
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:759210574"
     variation       72
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1040176449"
     variation       73
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1370818495"
     variation       74
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:868265725"
     variation       75
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:140408996"
     variation       79
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933344362"
     variation       81
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:933980437"
     variation       92
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933344480"
     variation       96
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="aa"
                     /db_xref="dbSNP:1289473717"
     variation       98
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:752314939"
     variation       99
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:923881074"
     exon            111..2921
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /inference="alignment:Splign:2.1.0"
     variation       118
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1208549824"
     variation       120
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:1933493664"
     variation       122
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1933493727"
     variation       123
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933493778"
     variation       128
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1471173288"
     variation       134
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1933493911"
     variation       137
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:896896455"
     variation       143
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1191113016"
     variation       154
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1047512402"
     variation       156
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:113920114"
     variation       157
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1933494204"
     variation       164
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:768917467"
     variation       165
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2147795655"
     variation       167
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1933494331"
     variation       168..173
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="gaga"
                     /replace="gagaga"
                     /db_xref="dbSNP:1933494403"
     variation       171
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1187775552"
     variation       180
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:888663699"
     variation       189
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:183323379"
     variation       191
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1933494648"
     variation       194
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:1933494732"
     variation       195
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1204039009"
     misc_feature    196..198
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /note="upstream in-frame stop codon"
     variation       200
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1325476639"
     variation       207
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:998368831"
     variation       212
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:1256397132"
     variation       221
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1933495019"
     variation       222
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1933495115"
     variation       224
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1253584271"
     variation       227
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:1006233291"
     variation       228
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1297730800"
     variation       231
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1933495534"
     variation       236
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1569290124"
     variation       238..267
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="cctgaagac"
                     /replace="cctgaagacaagggagcagtccctgaagac"
                     /db_xref="dbSNP:1933495744"
     variation       242..249
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="aag"
                     /replace="aagacaag"
                     /db_xref="dbSNP:1933495838"
     variation       247
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1933495941"
     variation       249
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:747787877"
     variation       250
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1933496132"
     variation       253
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1394396016"
     variation       254
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:2147795696"
     variation       265
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:2147795698"
     variation       267
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1244391417"
     variation       268
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:758062602"
     variation       276
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:778068250"
     variation       277
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:964209255"
     variation       286
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1392557192"
     variation       287
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:747351580"
     variation       288
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1933496899"
     CDS             289..981
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /note="SP82"
                     /codon_start=1
                     /product="claudin-2"
                     /protein_id="NP_001164566.1"
                     /db_xref="CCDS:CCDS14524.1"
                     /db_xref="GeneID:9075"
                     /db_xref="HGNC:HGNC:2041"
                     /db_xref="MIM:300520"
                     /translation="
MASLGLQLVGYILGLLGLLGTLVAMLLPSWKTSSYVGASIVTAVGFSKGLWMECATHSTGITQCDIYSTLLGLPADIQAAQAMMVTSSAISSLACIISVVGMRCTVFCQESRAKDRVAVAGGVFFILGGLLGFIPVAWNLHGILRDFYSPLVPDSMKFEIGEALYLGIISSLFSLIAGIILCFSCSSQRNRSNYYDAYQAQPLATRSSPRPGQPPKVKSEFNSYSLTGYV"
     misc_feature    310..372
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /note="propagated from UniProtKB/Swiss-Prot (P57739.1);
                     transmembrane region"
     misc_feature    355..831
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /note="PMP-22/EMP/MP20/Claudin family; Region:
                     PMP22_Claudin; cl21598"
                     /db_xref="CDD:473919"
     misc_feature    481..483
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /note="Paracellular cation selectivity.
                     /evidence=ECO:0000250|UniProtKB:O88552; propagated from
                     UniProtKB/Swiss-Prot (P57739.1); other site"
     misc_feature    532..594
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /note="propagated from UniProtKB/Swiss-Prot (P57739.1);
                     transmembrane region"
     misc_feature    637..699
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /note="propagated from UniProtKB/Swiss-Prot (P57739.1);
                     transmembrane region"
     misc_feature    775..837
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /note="propagated from UniProtKB/Swiss-Prot (P57739.1);
                     transmembrane region"
     misc_feature    901..978
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /note="propagated from UniProtKB/Swiss-Prot (P57739.1);
                     Region: Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite"
     misc_feature    943..945
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /note="Phosphoserine.
                     /evidence=ECO:0000250|UniProtKB:O88552; propagated from
                     UniProtKB/Swiss-Prot (P57739.1); phosphorylation site"
     misc_feature    955..957
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /note="Phosphoserine.
                     /evidence=ECO:0000250|UniProtKB:O88552; propagated from
                     UniProtKB/Swiss-Prot (P57739.1); phosphorylation site"
     misc_feature    973..978
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /note="propagated from UniProtKB/Swiss-Prot (P57739.1);
                     Region: Interactions with TJP1, TJP2 and TJP3.
                     /evidence=ECO:0000250"
     variation       297
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1050947241"
     variation       301
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1339788803"
     variation       302
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1174689287"
     variation       311
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1165776868"
     variation       314
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:771374270"
     variation       315
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1933497606"
     variation       316
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1933497671"
     variation       317
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:776970197"
     variation       336
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1006766993"
     variation       339
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2046912333"
     variation       344
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:151003816"
     variation       346
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1441579095"
     variation       348
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:769979747"
     variation       350
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:375239457"
     variation       352
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1225428237"
     variation       355
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:763199682"
     variation       369
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1322581753"
     variation       372
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1707367563"
     variation       375
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:141147283"
     variation       385
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:773012005"
     variation       386
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1933498654"
     variation       387
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933498733"
     variation       393
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933498790"
     variation       396
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:760367001"
     variation       397
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:766238256"
     variation       399
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933499011"
     variation       405
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1933499076"
     variation       407
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:753717485"
     variation       416
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933499204"
     variation       417
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:754968467"
     variation       433
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:2147795815"
     variation       454
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1340271277"
     variation       455
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:764672394"
     variation       459
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1253322406"
     variation       462
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1197923613"
     variation       464
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1428983841"
     variation       468
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:923605747"
     variation       471
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1358867065"
     variation       473
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933499801"
     variation       481
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:387907423"
     variation       484
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:752232715"
     variation       489
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:144975285"
     variation       492
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1602463347"
     variation       495
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:777266817"
     variation       507
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:2147795842"
     variation       510
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:369821153"
     variation       511
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:138837133"
     variation       512
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2147795850"
     variation       516
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:757556657"
     variation       532
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:750248939"
     variation       534
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933500564"
     variation       543
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:199729528"
     variation       544
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1299571339"
     variation       546
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:781662821"
     variation       549
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:746302840"
     variation       555
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1933500855"
     variation       570
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1933500923"
     variation       574
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:774565639"
     variation       582
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1223885391"
     variation       586
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1285034346"
     variation       588
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:770428538"
     variation       590
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1194923745"
     variation       592
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:780242387"
     variation       600
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:916721142"
     variation       606
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:749402798"
     variation       611
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:768907606"
     variation       612
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2147795897"
     variation       622
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1163686076"
     variation       623
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:774406442"
     variation       625
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:762164452"
     variation       626
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:770621723"
     variation       633
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:776503740"
     variation       635
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:2147795915"
     variation       641
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1371738496"
     variation       642
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1446301117"
     variation       644
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:759405019"
     variation       647
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1168737487"
     variation       648
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1421690119"
     variation       651
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:765178431"
     variation       654
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:752676378"
     variation       655
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:762416149"
     variation       656
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:763723377"
     variation       657
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:751157579"
     variation       666
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1046516234"
     variation       675
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1180765203"
     variation       676
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1405527623"
     variation       685
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:756945099"
     variation       687
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1324491659"
     variation       694
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:867807470"
     variation       697
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1933503017"
     variation       705
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933503085"
     variation       707
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:1602463484"
     variation       710
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1226193123"
     variation       711
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1179022340"
     variation       716
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:373340705"
     variation       719
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:781343821"
     variation       721
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1343608436"
     variation       722
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:200980922"
     variation       726
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:756640886"
     variation       732
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933503740"
     variation       734
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1490646672"
     variation       736
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1569290268"
     variation       737
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1225424186"
     variation       744
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:773581067"
     variation       750
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:140513089"
     variation       761
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:150418351"
     variation       762
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1248266075"
     variation       768
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1194085483"
     variation       769
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1555979575"
     variation       774
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1933504527"
     variation       775
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:940952718"
     variation       779
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:1602463548"
     variation       780
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933504729"
     variation       784
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:768614767"
     variation       791
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:770506958"
     variation       792
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1423720929"
     variation       798
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:1933504949"
     variation       806
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:2147796017"
     variation       810
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:387907422"
     variation       813
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1240174457"
     variation       815
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1337976305"
     variation       819
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1933505157"
     variation       827
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933505232"
     variation       844
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1330462225"
     variation       848
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:377500294"
     variation       851
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:779109711"
     variation       858
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933505552"
     variation       859
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:748262983"
     variation       860
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:138227214"
     variation       861
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:918298567"
     variation       868
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933505877"
     variation       871
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1420501590"
     variation       873
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:776235840"
     variation       874
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:371377414"
     variation       876
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:200850588"
     variation       878
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:941607638"
     variation       881
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1007147163"
     variation       886
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:769614194"
     variation       888
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1043568277"
     variation       889
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:775398321"
     variation       896
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933506655"
     variation       903
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:149607136"
     variation       909
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1365377833"
     variation       910
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:763452096"
     variation       911
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:751085480"
     variation       914
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1933507064"
     variation       918
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1933507141"
     variation       922
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:767221740"
     variation       927
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:903761545"
     variation       933
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:750149991"
     variation       934
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:144353049"
     variation       948
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:752176611"
     variation       953
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1933507602"
     variation       956
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1463118604"
     variation       960
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:754385986"
     variation       962
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:755524810"
     variation       963
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933507919"
     variation       969
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:778796184"
     variation       971
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1933508060"
     variation       972
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:748294630"
     variation       974
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1933508203"
     variation       983
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:758454165"
     variation       989
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:199803730"
     variation       991
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1183247319"
     variation       992
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1487375584"
     variation       993
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:747295372"
     variation       999
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1446531289"
     variation       1001..1006
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="ggggg"
                     /replace="gggggg"
                     /db_xref="dbSNP:1933508658"
     variation       1001
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1013632794"
     variation       1006
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1361984240"
     variation       1007
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933508798"
     variation       1012
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1024159272"
     variation       1013
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:769560991"
     variation       1017..1020
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="tg"
                     /replace="tgtg"
                     /db_xref="dbSNP:753226000"
     variation       1029
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:1223314804"
     variation       1036
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="cc"
                     /db_xref="dbSNP:1933509110"
     variation       1038
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:763951976"
     variation       1039
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933509164"
     variation       1041
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1029793431"
     variation       1042
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1933509285"
     variation       1045
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1933509379"
     variation       1047
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933509430"
     variation       1048
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933509489"
     variation       1054
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="t"
                     /replace="tt"
                     /db_xref="dbSNP:1933509549"
     variation       1055
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1933509613"
     variation       1062
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1933509661"
     variation       1069
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:760647123"
     variation       1075
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:985353276"
     variation       1076
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1016465854"
     variation       1084
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1933509934"
     variation       1088
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1602463748"
     variation       1089
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933510046"
     variation       1092
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1187932935"
     variation       1094..1098
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="ga"
                     /replace="gagga"
                     /db_xref="dbSNP:1173935028"
     variation       1100
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1933510341"
     variation       1124
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1469120360"
     variation       1125
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1933510483"
     variation       1130
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1430213662"
     variation       1138
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:374633456"
     variation       1141
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1427753487"
     variation       1144
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:191880523"
     variation       1146
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1933510708"
     variation       1148
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:767031230"
     variation       1149
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1933510890"
     variation       1153
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1933510931"
     variation       1156
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:918215242"
     variation       1158
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1933511016"
     variation       1172
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933511073"
     variation       1181
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:933666615"
     variation       1183
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933511171"
     variation       1184
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:754393914"
     variation       1188
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:910947988"
     variation       1192
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1602463797"
     variation       1193
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1030639588"
     variation       1195..1200
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="ct"
                     /replace="ctttct"
                     /db_xref="dbSNP:754666261"
     variation       1198..1200
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="t"
                     /replace="tct"
                     /db_xref="dbSNP:2147796201"
     variation       1206
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:376522492"
     variation       1207
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:942487142"
     variation       1211
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1349375470"
     variation       1212
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1043537300"
     variation       1214
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:989380513"
     variation       1225
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:755453835"
     variation       1229
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1363071254"
     variation       1230
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1225026609"
     variation       1234
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1359444888"
     variation       1240
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1269010559"
     variation       1242
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:200371519"
     variation       1243
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1328074593"
     variation       1248
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1334666073"
     variation       1265
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1296027863"
     variation       1274
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1362142694"
     variation       1280
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1933512431"
     variation       1283
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:16987204"
     variation       1285
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1023597988"
     variation       1287
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:781381086"
     variation       1288
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933512714"
     variation       1298
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1052307518"
     variation       1304
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1933512824"
     variation       1306
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1288471544"
     variation       1331
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:779363433"
     variation       1334
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:981899851"
     variation       1337
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:927804897"
     variation       1341
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1476460542"
     variation       1343
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:748203460"
     variation       1346
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:2147796247"
     variation       1347
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1183586731"
     variation       1349..1352
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace=""
                     /replace="gacc"
                     /db_xref="dbSNP:1933513354"
     variation       1349
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:183625207"
     variation       1351
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933513405"
     variation       1352
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:930046697"
     variation       1353..1356
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="ctct"
                     /replace="ctctct"
                     /db_xref="dbSNP:1933513537"
     variation       1384
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1485418465"
     variation       1393..1394
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace=""
                     /replace="tt"
                     /db_xref="dbSNP:1933513676"
     variation       1395
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1853350578"
     variation       1397
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1933513733"
     variation       1401
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933513799"
     variation       1412..1414
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="ggg"
                     /replace="gggg"
                     /db_xref="dbSNP:1202868595"
     variation       1416..1420
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="ag"
                     /replace="aggag"
                     /db_xref="dbSNP:1933513925"
     variation       1420
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:983299811"
     variation       1421
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1933514064"
     variation       1428
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1933514134"
     variation       1431..1434
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="ttt"
                     /replace="tttt"
                     /replace="ttttt"
                     /db_xref="dbSNP:778150160"
     variation       1434
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933514291"
     variation       1437
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1214619280"
     variation       1438
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:572499503"
     variation       1439
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1933514454"
     variation       1440
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1312821032"
     variation       1447
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933514576"
     variation       1451
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933514632"
     variation       1454
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1023666118"
     variation       1470
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace=""
                     /replace="t"
                     /db_xref="dbSNP:1933514742"
     variation       1480
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1602463942"
     variation       1488
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:941404389"
     variation       1501
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:749662629"
     variation       1503
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933515021"
     variation       1504
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933515108"
     variation       1509
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1933515197"
     variation       1512
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1439784475"
     variation       1514
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:1933515388"
     variation       1516
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:905258957"
     variation       1518
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1354137394"
     variation       1521
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1933515650"
     variation       1528
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1006350382"
     variation       1535
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1329843379"
     variation       1543
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1933515911"
     variation       1544
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1016436169"
     variation       1545
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:962214642"
     variation       1546
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1933516155"
     variation       1548
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1933516253"
     variation       1549
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:1933516352"
     variation       1550
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1383529237"
     variation       1558..1561
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="aaaa"
                     /replace="aaaaa"
                     /db_xref="dbSNP:1933516526"
     variation       1564
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1163020561"
     variation       1570
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:972284147"
     variation       1571
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1039924368"
     variation       1573
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933516954"
     variation       1575
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933517034"
     variation       1576
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1445097089"
     variation       1579
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1933517192"
     variation       1580
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:771330771"
     variation       1584
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933517400"
     variation       1587
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:955010979"
     variation       1591
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1933517593"
     variation       1606
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:986852663"
     variation       1608
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1933517806"
     variation       1613
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:910927841"
     variation       1618
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:900060604"
     variation       1619
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933518128"
     variation       1625
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1403729492"
     variation       1629
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1288879315"
     variation       1631
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933518404"
     variation       1632
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933518500"
     variation       1641
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1128218"
     variation       1647
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:1346071962"
     variation       1648
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1933518864"
     variation       1649..1657
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="aaaaa"
                     /replace="aaaaaaaa"
                     /replace="aaaaaaaaa"
                     /replace="aaaaaaaaaa"
                     /db_xref="dbSNP:759145216"
     variation       1650
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1456924720"
     variation       1656
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:1318869665"
     variation       1657
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:867306371"
     variation       1658
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1933519422"
     variation       1679
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1933519512"
     variation       1686
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:2147796376"
     variation       1687
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1385471805"
     variation       1691
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1453943065"
     variation       1693
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1933519790"
     variation       1696
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:771733386"
     variation       1698
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1284177053"
     variation       1704
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1933520057"
     variation       1709
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933520153"
     variation       1712
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:41309528"
     variation       1716
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:760105451"
     variation       1720
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1302584554"
     variation       1721
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:972096283"
     variation       1722
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933520702"
     variation       1724
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:979159103"
     variation       1725
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="aa"
                     /db_xref="dbSNP:1713557154"
     variation       1728
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:764086272"
     variation       1729
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933520976"
     variation       1730..1740
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="gaggaaagcac"
                     /replace="gaggaaagcacgaggaaagcac"
                     /db_xref="dbSNP:1284505266"
     variation       1741
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1933521152"
     variation       1750
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1933521234"
     variation       1751..1757
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="aaga"
                     /replace="aagaaga"
                     /db_xref="dbSNP:1157601776"
     variation       1755
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:1327975160"
     variation       1761..1762
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="gg"
                     /replace="ggg"
                     /db_xref="dbSNP:200233084"
     variation       1764
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1179326894"
     variation       1770
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1473347848"
     variation       1771
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2147796421"
     variation       1778
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:761681083"
     variation       1782
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1221064448"
     variation       1783
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:765163859"
     variation       1787
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933521807"
     variation       1790..1795
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="gactcc"
                     /replace="gactccgactcc"
                     /db_xref="dbSNP:1267143367"
     variation       1792
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933521924"
     variation       1801
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:935183925"
     variation       1820
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:903364031"
     variation       1821
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1933522111"
     variation       1823
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:1933522165"
     variation       1830
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1933522215"
     variation       1831
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1933522272"
     variation       1836
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933522334"
     variation       1841
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1235706727"
     variation       1846
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1052276795"
     variation       1847
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933522527"
     variation       1855
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1471850304"
     variation       1856
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:7883582"
     variation       1857
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1825830632"
     variation       1864
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1282931637"
     variation       1871
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1933522778"
     variation       1873
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933522840"
     variation       1878
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1405594851"
     variation       1884
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1347536629"
     variation       1890
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:999272013"
     variation       1891..1902
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="ggcta"
                     /replace="ggctaagggcta"
                     /db_xref="dbSNP:1453596416"
     variation       1895..1896
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="aa"
                     /db_xref="dbSNP:1933523254"
     variation       1898
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1933523335"
     variation       1906
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1933523431"
     variation       1911
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:980248325"
     variation       1912
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:949356395"
     variation       1922
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1933523685"
     variation       1923..1924
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="aa"
                     /db_xref="dbSNP:1031193019"
     variation       1925
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933523876"
     variation       1928
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1045470856"
     variation       1930
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1933524079"
     variation       1938
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933524166"
     variation       1939
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933524242"
     variation       1940
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1933524337"
     variation       1942
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:755206308"
     variation       1948
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1468618129"
     variation       1949
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:905228764"
     variation       1960
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1198325716"
     variation       1966
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1006278229"
     variation       1969
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933524835"
     variation       1970
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1933524910"
     variation       1973
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:893472718"
     variation       1982
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1268771437"
     variation       1984..1987
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="ggg"
                     /replace="gggg"
                     /db_xref="dbSNP:755582862"
     variation       1984
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1184260913"
     variation       1985
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1602464146"
     variation       1990
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933525425"
     variation       1991
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:1010613160"
     variation       1995
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:187325704"
     variation       1998
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1157242320"
     variation       2003
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2081095094"
     variation       2005
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:1933525787"
     variation       2007
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:73533029"
     variation       2013
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:969267590"
     variation       2014
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1933526083"
     variation       2017
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1933526166"
     variation       2019
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933526247"
     variation       2020
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="t"
                     /replace="tt"
                     /db_xref="dbSNP:1933526323"
     variation       2023
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1933526405"
     variation       2028
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1262741766"
     variation       2030
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1602464170"
     variation       2031
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:192635116"
     variation       2034
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1933526678"
     variation       2037
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:982037199"
     variation       2047
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1933526836"
     variation       2049
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:993651568"
     variation       2052
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:1933527013"
     variation       2053..2060
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="gt"
                     /replace="gtgggtgt"
                     /db_xref="dbSNP:1034844997"
     variation       2057
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:778318354"
     variation       2063
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933527311"
     variation       2064
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1933527391"
     variation       2067
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:1602464186"
     variation       2072
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933527525"
     variation       2075
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1293477754"
     variation       2085..2089
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="ccccc"
                     /replace="cccccc"
                     /db_xref="dbSNP:1334078065"
     variation       2085
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933527649"
     variation       2087
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1030521600"
     variation       2090
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1933527836"
     variation       2092
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:951313095"
     variation       2096
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1933527969"
     variation       2101
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933528029"
     variation       2105
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1602464204"
     variation       2106
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace=""
                     /replace="g"
                     /db_xref="dbSNP:982884104"
     variation       2106
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:955125195"
     variation       2111
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1445010608"
     variation       2113
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1933528313"
     variation       2116
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1177620206"
     variation       2123
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1279565556"
     variation       2125
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:749797089"
     variation       2126
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:941456311"
     variation       2132
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933528785"
     variation       2134
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1167642904"
     variation       2136
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1007842765"
     variation       2137..2143
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="cccccc"
                     /replace="ccccccc"
                     /replace="cccccccc"
                     /replace="ccccccccc"
                     /db_xref="dbSNP:777233825"
     variation       2138
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1459801475"
     variation       2139
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1242240915"
     variation       2141
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1018323664"
     variation       2142
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1933529621"
     variation       2143
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1933529693"
     variation       2144
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1226138814"
     variation       2146
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:184610738"
     variation       2151
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1933529994"
     variation       2152
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933530082"
     variation       2153
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1249886275"
     variation       2158
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:779196711"
     variation       2160
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1308223987"
     variation       2167..2170
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="ag"
                     /replace="agag"
                     /db_xref="dbSNP:1933530456"
     variation       2171
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:147829672"
     variation       2179
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:1933530703"
     variation       2182
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:921283334"
     variation       2183
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1439418990"
     variation       2184
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:2147796635"
     variation       2189
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1337754013"
     variation       2194
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1205169441"
     variation       2195
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1403875070"
     variation       2196
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:141297568"
     variation       2199
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933531384"
     variation       2206
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:934216616"
     variation       2210
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:956485078"
     variation       2211
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1051814528"
     variation       2212
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:924786790"
     variation       2219..2223
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="gtcca"
                     /replace="gtccagtcca"
                     /db_xref="dbSNP:1442626557"
     variation       2219
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1384560660"
     variation       2223
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:775069708"
     variation       2224
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1425380488"
     variation       2226
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:987916679"
     variation       2227
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:917799064"
     variation       2228
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:1933532433"
     variation       2236
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1276782566"
     variation       2246
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:1933532617"
     variation       2248
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1431803991"
     variation       2253
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:949321986"
     variation       2261
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1480960024"
     variation       2263
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1052185255"
     variation       2268
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:893519288"
     variation       2276
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1010676925"
     variation       2280
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1044998511"
     variation       2288
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:926579900"
     variation       2289
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:145166443"
     variation       2294..2298
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="tgt"
                     /replace="tgtgt"
                     /db_xref="dbSNP:1304391959"
     variation       2296
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:878973134"
     variation       2298
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2063898797"
     variation       2317
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1044721618"
     variation       2320
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:904886092"
     variation       2321
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:1933533559"
     variation       2322
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1309268282"
     variation       2323
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933533682"
     variation       2328
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1422270796"
     variation       2329
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1037732398"
     variation       2330
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:1163841985"
     variation       2334
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:1933533914"
     variation       2335
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:897892712"
     variation       2339
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1035386486"
     variation       2343
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:745435515"
     variation       2354
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1933534152"
     variation       2370
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1933534216"
     variation       2372..2374
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="aga"
                     /db_xref="dbSNP:1180829728"
     variation       2383
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1419855621"
     variation       2388
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1822830889"
     variation       2389
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:951237979"
     variation       2394
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:993619322"
     variation       2395
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1197334973"
     variation       2397
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1602464404"
     variation       2407..2409
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="tt"
                     /replace="ttt"
                     /db_xref="dbSNP:771337109"
     variation       2408
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1933534669"
     variation       2411
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1330173589"
     variation       2413
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1369382611"
     variation       2421
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1407504770"
     variation       2422
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1304580367"
     variation       2428
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1933534977"
     variation       2429
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1293133173"
     variation       2431
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:769158456"
     variation       2432
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:1004419212"
     variation       2433
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1260436024"
     variation       2435
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:1933535250"
     variation       2441
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:373807733"
     variation       2444
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1933535357"
     variation       2451
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:186720703"
     variation       2452
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1016771138"
     variation       2454
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1289881056"
     variation       2457
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1402553812"
     variation       2463
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1933535555"
     variation       2466
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1933535616"
     variation       2478
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:1344384425"
     variation       2479
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:1323660980"
     variation       2480
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1406953096"
     variation       2483
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:780022444"
     variation       2492
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1933535890"
     variation       2498
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2147796780"
     variation       2504
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1157729882"
     variation       2505
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1457615982"
     variation       2509
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1232079457"
     variation       2513
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1685133009"
     variation       2514
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933536131"
     variation       2520
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:201099546"
     variation       2522
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:975483117"
     variation       2526
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1272814342"
     variation       2527
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1933536405"
     variation       2528
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:890637044"
     variation       2533
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:749161015"
     variation       2539
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1933536659"
     variation       2543
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1008185180"
     variation       2545
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:921252090"
     variation       2551
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1261703235"
     variation       2552
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:768441150"
     variation       2558
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933537048"
     variation       2559
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1206059325"
     variation       2560
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933537240"
     variation       2563
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933537310"
     variation       2572
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1331747466"
     variation       2578
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1269618855"
     variation       2581
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933537582"
     variation       2585
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1933537675"
     variation       2591
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1221244497"
     variation       2592
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1933537835"
     variation       2597
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:963653805"
     variation       2599
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:2147796834"
     variation       2600
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1933538005"
     variation       2604
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:192199825"
     variation       2605
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:774091882"
     variation       2606
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1273876982"
     variation       2607
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:748340523"
     variation       2608
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:772383789"
     variation       2617
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:956455777"
     variation       2624
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:955400201"
     variation       2625
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1203177441"
     variation       2627
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1271156409"
     variation       2633
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1933538927"
     variation       2636
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:776602466"
     variation       2640
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1317603558"
     variation       2645
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1198463696"
     variation       2646
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:1390634814"
     variation       2651
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933539272"
     variation       2654
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1174004516"
     variation       2655
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1266588979"
     variation       2656
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933539561"
     variation       2662
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1426173249"
     variation       2663
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:1358982432"
     variation       2667
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:761802048"
     variation       2673
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933539879"
     variation       2678
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1174338721"
     variation       2681
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:917711333"
     variation       2682
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:1933540148"
     variation       2686
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:773273862"
     variation       2693
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1933540329"
     variation       2697
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933540390"
     variation       2702
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:987070328"
     variation       2703
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1245296801"
     variation       2708
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:970591926"
     variation       2711..2715
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="cccc"
                     /replace="ccccc"
                     /db_xref="dbSNP:1189847520"
     variation       2719
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:981065507"
     variation       2720
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1241616633"
     variation       2721
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:926512216"
     variation       2724
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:941948344"
     variation       2729
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933541210"
     variation       2731
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1169752336"
     variation       2732
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:1602464597"
     variation       2735
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1933541482"
     variation       2736..2741
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="ctt"
                     /replace="cttctt"
                     /db_xref="dbSNP:1933541567"
     variation       2738
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:934938927"
     variation       2739
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /replace="g"
                     /db_xref="dbSNP:147588227"
     variation       2740
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:1164875011"
     variation       2746
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:919291399"
     variation       2751
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1228977913"
     variation       2767
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:367974655"
     variation       2772
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:773087022"
     variation       2773
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:929340273"
     variation       2774..2779
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="tt"
                     /replace="ttattt"
                     /db_xref="dbSNP:1933542357"
     variation       2775
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1451674765"
     variation       2776
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1933542539"
     variation       2779..2791
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="tgtgtgtgtgt"
                     /replace="tgtgtgtgtgtgt"
                     /replace="tgtgtgtgtgtgtgt"
                     /db_xref="dbSNP:766584577"
     variation       2787
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:904856493"
     variation       2789
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:760876206"
     variation       2792
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1602464638"
     variation       2798
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933543075"
     variation       2802
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:762850832"
     variation       2809
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933543241"
     variation       2810
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1051859941"
     variation       2811
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1933543407"
     variation       2816
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1933543496"
     variation       2821
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933543584"
     variation       2822
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1327946869"
     variation       2830
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1395792399"
     variation       2831
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1169313136"
     variation       2840
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:767777714"
     variation       2841..2852
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="ct"
                     /replace="ctagacctctct"
                     /db_xref="dbSNP:1933544046"
     variation       2842
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1451841557"
     variation       2848
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1003653062"
     variation       2857..2861
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="ccccc"
                     /replace="cccccc"
                     /db_xref="dbSNP:1183348344"
     variation       2858
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:2147796960"
     variation       2861
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:890596206"
     variation       2877
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="g"
                     /replace="t"
                     /db_xref="dbSNP:1933544507"
     variation       2881
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1602464670"
     variation       2882
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1473352127"
     variation       2885
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="c"
                     /db_xref="dbSNP:1933544663"
     variation       2891
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1933544718"
     variation       2892
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:752922976"
     variation       2896
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933544850"
     variation       2900
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="c"
                     /replace="t"
                     /db_xref="dbSNP:1933544927"
     regulatory      2901..2906
                     /regulatory_class="polyA_signal_sequence"
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /note="hexamer: AATAAA"
     variation       2918
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="t"
                     /db_xref="dbSNP:1933544998"
     variation       2919
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /replace="a"
                     /replace="g"
                     /db_xref="dbSNP:1211868419"
     polyA_site      2921
                     /gene="CLDN2"
                     /gene_synonym="claudin-2; OAZON"
                     /note="major polyA site"
ORIGIN      
aggcatggctgcccttttagcgtgtcccagcctgccaagagggagtgccctggagagacccttgctcaggagcactgccaggggatcagtgccccatttgtacctgcaaggtcttctagatgccttcttgaggctgcttgtggccacccacagacacttgtaaggaggagagaagtcagcctggcagagagactctgaaatgagggattagaggtgttcaaggagcaagagcttcagcctgaagacaagggagcagtccctgaagacgcttctactgagaggtctgccatggcctctcttggcctccaacttgtgggctacatcctaggccttctggggcttttgggcacactggttgccatgctgctccccagctggaaaacaagttcttatgtcggtgccagcattgtgacagcagttggcttctccaagggcctctggatggaatgtgccacacacagcacaggcatcacccagtgtgacatctatagcacccttctgggcctgcccgctgacatccaggctgcccaggccatgatggtgacatccagtgcaatctcctccctggcctgcattatctctgtggtgggcatgagatgcacagtcttctgccaggaatcccgagccaaagacagagtggcggtagcaggtggagtctttttcatccttggaggcctcctgggattcattcctgttgcctggaatcttcatgggatcctacgggacttctactcaccactggtgcctgacagcatgaaatttgagattggagaggctctttacttgggcattatttcttccctgttctccctgatagctggaatcatcctctgcttttcctgctcatcccagagaaatcgctccaactactacgatgcctaccaagcccaacctcttgccacaaggagctctccaaggcctggtcaacctcccaaagtcaagagtgagttcaattcctacagcctgacagggtatgtgtgaagaaccaggggccagagctggggggtggctgggtctgtgaaaaacagtggacagcaccccgagggccacaggtgagggacactaccactggatcgtgtcagaaggtgctgctgaggatagactgactttggccattggattgagcaaaggcagaaatgggggctagtgtaacagcatgcaggttgaattgccaaggatgctcgccatgccagcctttctgttttcctcaccttgctgctcccctgccctaagtccccaaccctcaacttgaaaccccattcccttaagccaggactcagaggatccctttgccctctggtttacctgggactccatccccaaacccactaatcacatcccactgactgaccctctgtgatcaaagaccctctctctggctgaggttggctcttagctcattgctggggatgggaaggagaagcagtggcttttgtgggcattgctctaacctacttctcaagcttccctccaaagaaactgattggccctggaacctccatcccactcttgttatgactccacagtgtccagactaatttgtgcatgaactgaaataaaaccatcctacggtatccagggaacagaaagcaggatgcaggatgggaggacaggaaggcagcctgggacatttaaaaaaataaaaatgaaaaaaaaacccagaacccatttctcagggcactttccagaattctctcatatttgtgggctgggatcaagcctgcagcttgaggaaagcacaaggaaaggaaagaagatctggtggaaagctcaggtggcagcggactctgactccactgaggaactgcctcagaagctgcgatcacaactttggctgaagcccctgcctcactctagggcacctgacctggcctcttgcctaaaccacaaggctaagggctatagacaatggtttccttaggaacagtaaaccagtttttctagggatggcccttggctgggggatgacagtgtgggagctgtggggtactgaggaagacaccattccttgacggtgtctaagaagccaggtggatgtgtgtggtggctccagtgggtgtttctactctgccagtgagaggcagccccctagaaactcttcaggcgtaatggaaaatcagctcaaatgagatcaggcccccccagggtccacccacagagcactacagagcctctgaaagaccatagcaccaagcgagccccttcagattcccccactgtccatcggaagatgctccagagtggctagagggcatctaagggctccagcatggcatatccatgcccacggtgctgtgtccatgatctgagtgatagctgcactgctgcctgggattgcagctgaggtgggagtggagaatggttcccaggaagacagttccacctctaaggtccgaaaatgttccctttaccctggagtgggagtgaggggtcatacaccaaaggtattttccctcaccagtctaggcatgactggcttctgaaaaattccagcacacctcctcgaacctcattgtcagcagagagggcccatctgttgtctgtaacatgcctttcacatgtccaccttcttgccatgttccagctgctctcccaacctggaaggccgtctccccttagccaagtcctcctcaggcttggagaacttcctcagcgtcacctccttcattgagccttctctgatcactccatccctctcctacccctccctcccccaaccctcaatgtataaattgcttcttgatgcttagcattcacaatttttgattgatcgttatttgtgtgtgtgtgtccgatctcacaagtatattgtaaacccttcggtgggtgggggccatatcctagacctctctgtatcccccagactatctgtaacagtgccaggcacacagtaggtgatcaataaacacttgttgattgag
//

by @meso_cacase at DBCLS
This page is licensed under a Creative Commons Attribution 4.0 International License (CC BY 4.0).

If you use GGRNA in your work, please cite:
Naito Y, Bono H. (2012)
GGRNA: an ultrafast, transcript-oriented search engine for genes and transcripts.
Nucleic Acids Res., 40, W592-W596. [Full Text]