LOCUS       NM_001397674            2566 bp    mRNA    linear   VRT 24-SEP-2023
DEFINITION  Gallus gallus PBX homeobox 3 (PBX3), transcript variant 7, mRNA.
ACCESSION   NM_001397674
VERSION     NM_001397674.1
KEYWORDS    RefSeq.
SOURCE      Gallus gallus (chicken)
  ORGANISM  Gallus gallus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
            Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes;
            Phasianidae; Phasianinae; Gallus.
REFERENCE   1  (bases 1 to 2566)
  AUTHORS   Tang H, Finn RD and Thomas PD.
  TITLE     TreeGrafter: phylogenetic tree-based annotation of proteins with
            Gene Ontology terms and other annotations
  JOURNAL   Bioinformatics 35 (3), 518-520 (2019)
   PUBMED   30032202
REFERENCE   2  (bases 1 to 2566)
  AUTHORS   Burge S, Kelly E, Lonsdale D, Mutowo-Muellenet P, McAnulla C,
            Mitchell A, Sangrador-Vegas A, Yong SY, Mulder N and Hunter S.
  TITLE     Manual GO annotation of predictive protein signatures: the InterPro
            approach to GO curation
  JOURNAL   Database (Oxford) 2012, bar068 (2012)
   PUBMED   22301074
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2566)
  AUTHORS   Coy SE and Borycki AG.
  TITLE     Expression analysis of TALE family transcription factors during
            avian development
  JOURNAL   Dev Dyn 239 (4), 1234-1245 (2010)
   PUBMED   20235232
REFERENCE   4  (bases 1 to 2566)
  AUTHORS   Caldwell RB, Kierzek AM, Arakawa H, Bezzubov Y, Zaim J, Fiedler P,
            Kutter S, Blagodatski A, Kostovska D, Koter M, Plachy J, Carninci
            P, Hayashizaki Y and Buerstedde JM.
  TITLE     Full-length cDNAs from chicken bursal lymphocytes to facilitate
            gene function analysis
  JOURNAL   Genome Biol 6 (1), R6 (2005)
   PUBMED   15642098
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAENSK010000308.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR13267659.224732.1,
                                           SRR13267655.173278.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA103992290, SAMEA103992428
                                           [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-101               JAENSK010000308.1  9516766-9516866
            102-175             JAENSK010000308.1  9518416-9518489
            176-417             JAENSK010000308.1  9593882-9594123
            418-608             JAENSK010000308.1  9598665-9598855
            609-744             JAENSK010000308.1  9600346-9600481
            745-910             JAENSK010000308.1  9606974-9607139
            911-1000            JAENSK010000308.1  9609198-9609287
            1001-2566           JAENSK010000308.1  9611761-9613326
FEATURES             Location/Qualifiers
     source          1..2566
                     /organism="Gallus gallus"
                     /mol_type="mRNA"
                     /db_xref="taxon:9031"
                     /chromosome="17"
                     /map="17"
     gene            1..2566
                     /gene="PBX3"
                     /gene_synonym="Pbx3b"
                     /note="PBX homeobox 3"
                     /db_xref="CGNC:50438"
                     /db_xref="GeneID:417093"
     exon            1..101
                     /gene="PBX3"
                     /gene_synonym="Pbx3b"
                     /inference="alignment:Splign:2.1.0"
     misc_feature    73..75
                     /gene="PBX3"
                     /gene_synonym="Pbx3b"
                     /note="upstream in-frame stop codon"
     exon            102..175
                     /gene="PBX3"
                     /gene_synonym="Pbx3b"
                     /inference="alignment:Splign:2.1.0"
     CDS             127..957
                     /gene="PBX3"
                     /gene_synonym="Pbx3b"
                     /note="isoform 4 is encoded by transcript variant 7;
                     pre-B-cell leukemia transcription factor 3; pre-B-cell
                     leukemia homeobox 3"
                     /codon_start=1
                     /product="pre-B-cell leukemia transcription factor 3
                     isoform 4"
                     /protein_id="NP_001384603.1"
                     /db_xref="CGNC:50438"
                     /db_xref="GeneID:417093"
                     /translation="

MKPALFSVLCEIKEKTGLSIRGAQEEDPPDPQLMRLDNMLLAEGVSGPEKGGGSAAAAAAAAASGGSSDNSIEHSDYRAKLTQIRQIYHTELEKYEQACNEFTTHVMNLLREQSRTRPISPKEIERMVGIIHRKFSSIQMQLKQSTCEAVMILRSRFLDARRKRRNFSKQATEILNEYFYSHLSNPYPSEEAKEELAKKCSITVSQVSNWFGNKRIRYKKNIGKFQEEANLYAAKTAVTAAHAVAAAVQNNQTNSPTTPNSGGYPASCYQSDGRIQ"

     misc_feature    127..603
                     /gene="PBX3"
                     /gene_synonym="Pbx3b"
                     /note="PBC domain; Region: PBC; pfam03792"
                     /db_xref="CDD:461052"
     misc_feature    607..786
                     /gene="PBX3"
                     /gene_synonym="Pbx3b"
                     /note="Region: Homeodomain; pfam00046"
                     /db_xref="CDD:459649"
     exon            176..417
                     /gene="PBX3"
                     /gene_synonym="Pbx3b"
                     /inference="alignment:Splign:2.1.0"
     exon            418..608
                     /gene="PBX3"
                     /gene_synonym="Pbx3b"
                     /inference="alignment:Splign:2.1.0"
     exon            609..744
                     /gene="PBX3"
                     /gene_synonym="Pbx3b"
                     /inference="alignment:Splign:2.1.0"
     exon            745..910
                     /gene="PBX3"
                     /gene_synonym="Pbx3b"
                     /inference="alignment:Splign:2.1.0"
     exon            911..1000
                     /gene="PBX3"
                     /gene_synonym="Pbx3b"
                     /inference="alignment:Splign:2.1.0"
     exon            1001..2566
                     /gene="PBX3"
                     /gene_synonym="Pbx3b"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      

accggagcggccatcaaacaacataaagcacacacagtcaccgggcggccgcgctcataaatccccgccggctgatatttttgcacgttgctttgcacagagaagcacgcgctgaactgccacaggatgaagcccgcgctcttcagcgtcctctgcgagatcaaggagaaaacaggtttgagcatccgaggagcccaggaggaagaccctcccgatccccagctaatgagactagacaatatgcttctggcagaaggagtctcaggtccggagaaaggtgggggatcggcggcagcagctgcagccgcagcagcctctggagggtcttcagataactctattgaacactcagattacagagccaaattgacccagatcagacaaatctatcacacagagctggagaaatatgaacaggcatgtaatgaatttactacacatgtgatgaacctgctcagagaacagagccgaacgcgtcccatttctcctaaggagattgaaaggatggtgggcatcattcatcgaaaattcagctccatccagatgcagctcaagcaaagtacttgtgaagcagtcatgattttaaggtcgaggttccttgatgccagaaggaaaagacgcaacttcagtaaacaagccacagaaatactgaatgagtatttttactcccacctcagtaacccttaccccagtgaagaagccaaagaagagctggcaaagaagtgcagcatcacagtatcgcaggtctccaactggtttggcaataagagaattaggtacaagaagaacattgggaagttccaggaagaagccaatctttatgcagcgaagacggctgtgactgcagcgcatgccgtggccgcagccgtccagaacaaccagaccaactcccccaccacgccaaactctggtggataccctgcgtcatgttatcaatcagacgggaggatacagtgatggcttgggaggaaattcactgtacagtccacataatttaaatgctaatggaggctggcaggacgcaactactccatcttctgtgacttcccctacagaagggccgggaagtgtgcactctgatacctctaactaatctcctagcaacactttttccctgagctgagatgccttcatcagcgcagtcagagtcgcaggagaaaaaggaaagaatttttttgtagccaaccacctacagctttactgtaaaaccttgtcttactagaaaacttggtaaatctgttttttaaaggtatcataatcatttgtatttatacttaaaacacacaatgttaaaaagcactttatccaattgggccaagatttagcattgtttgtagccctgttactattttatcataatttattatcggcgattttaacagtgtcggtctaacagttgccaattacttggccttaagggtaaaagtacagtacaagcttaacctcaagagcaagagcgggcacaaaggaacagctcacctgaatctcaactgcgtgcatattttcgtgggaagtcaaaatgagttacagacttgggttgcgtttagccttttcatctctcttacagagttggaataaagaggtctgcttggttatttcggttaacagcggttgtgtttaagaatccttattcgtcacatttttgttgtgatctgttgctttgtaagttaggttgggtaccaggagcatctttccttgctgaccgccaggaccccccgcctgctctctgtatttcggcaatggactcagagtgttcttaagaggtgaagatattgctgcttctttcagtgagccaccagctgggttttacagtacgagtaggtgctgcgcggctgccgagatcggttacttcttctgggcagccaaacaaacacacagaaaacaaaaaggaaaagcgaaggaaaaagcaccattatatggattgttgtacatagtgtagcaaaagagtatttatacatctcaccaatcaaaacacagctttattacctcatgcgaactcatacgaaccaatagactttcaacatgttctgtagcttagagtgctcacttactacctctgaacgatactcacgctgtagtttgtctctttcttatctttttgcatcttgtaattaactctttgtttccctcataaattgtaatgtacattgtaatcttttaaaagaatcagggttgcgtttgcaacttttaaaagagctgaagtggaaacattgggtcttaggtttaacagaacagtgaaacttgtaaatactgagaaacattttgaatgttgttcatcttgttactaatccacgcaaaaaatacaactaattgtaatgcatacagacttcagtatcagtactgtatattcaccctgtgtaacagggggccctttctttctctcttttgtattgtatgcgattctgaaactgattgagtcatgaaaataatttgtggcagtgattctaatgtattaaaacgtttcgtgttactttctaactggattacaccctggattgagaagtcttcctcgtggtagttatatgtagtttcaaacatgaataaactttttgctttcatgatcaaa

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