LOCUS       XM_021477593            2041 bp    mRNA    linear   VRT 15-JUN-2017
DEFINITION  PREDICTED: Danio rerio iroquois homeobox 5a (irx5a), transcript
            variant X1, mRNA.
ACCESSION   XM_021477593
VERSION     XM_021477593.1
DBLINK      BioProject: PRJNA13922
KEYWORDS    RefSeq.
SOURCE      Danio rerio (zebrafish)
  ORGANISM  Danio rerio
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Danionidae; Danioninae; Danio.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_007118.7) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI
            Annotation Status           :: Full annotation
            Annotation Version          :: Danio rerio Annotation Release 106
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 7.4
            Annotation Method           :: Best-placed RefSeq; Gnomon
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2041
                     /organism="Danio rerio"
                     /mol_type="mRNA"
                     /strain="Tuebingen"
                     /db_xref="taxon:7955"
                     /chromosome="7"
     gene            1..2041
                     /gene="irx5a"
                     /gene_synonym="iro5"
                     /note="iroquois homeobox 5a; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 11
                     ESTs, 16 Proteins, and 100% coverage of the annotated
                     genomic feature by RNAseq alignments, including 143
                     samples with support for all annotated introns"
                     /db_xref="GeneID:573346"
                     /db_xref="ZFIN:ZDB-GENE-010716-2"
     CDS             400..1128
                     /gene="irx5a"
                     /gene_synonym="iro5"
                     /codon_start=1
                     /product="iroquois-class homeodomain protein IRX-5 isoform
                     X1"
                     /protein_id="XP_021333268.1"
                     /db_xref="GeneID:573346"
                     /db_xref="ZFIN:ZDB-GENE-010716-2"
                     /translation="

MAYPQGYLYQPSASLALYSCPAYSTSVISGPRTEELGRSSSGSAFAPYAGSTAFTSASPGYNSHLPYSADAAAAATFTSYVSSPYDHTTGMAGSIGYHPYAAPLGSYPYGDPAYRKNATRDATATLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWTPRNRSEDEEEDENIDLEKNDDDEPNKPTDKGDSTDTEITNSSTQGKYHATDLKTRLILKILIHL"

     misc_feature    <730..1098
                     /gene="irx5a"
                     /gene_synonym="iro5"
                     /note="Homeodomain-containing transcription factor
                     [Transcription]; Region: COG5576"
                     /db_xref="CDD:227863"
     misc_feature    order(742..747,751..753,811..813,829..831,868..870,
                     874..879,886..891,895..903,907..912)
                     /gene="irx5a"
                     /gene_synonym="iro5"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:238039"
     misc_feature    order(748..750,877..879,886..891,898..900)
                     /gene="irx5a"
                     /gene_synonym="iro5"
                     /note="specific DNA base contacts [nucleotide binding];
                     other site"
                     /db_xref="CDD:238039"
     misc_feature    787..903
                     /gene="irx5a"
                     /gene_synonym="iro5"
                     /note="Homeobox KN domain; Region: Homeobox_KN; pfam05920"
                     /db_xref="CDD:428673"
ORIGIN      

ttgccttttctttcgatgactacaccccgagaggaggagcgagaggctcatagtaggcgtcagaatcctcagttttcaacttagcatcctggcaggacactctccgaagcaaagccccatctgagagcaaaaaacttgtcccgcgcgctcggcatgagagtcacagagcgctcagagggtgagagagcgcctcgaaaatccgcgagcgagtctgacaacgactgattaacgagtgtgaagtctatgcaatcgtcgttctctttaatttccatcactgctagacgcgaggaggacaggacggaggtctgtttactcggaactctatgagcgagcgcggcgagcgcgtgagagtttgagggagaagaactcaagtgagaagcttatatttggatcttcaccatggcgtaccctcagggctacttgtatcagccatccgcctctttggcactctattcgtgtcctgcctacagtacaagcgtgatttcgggaccccggacagaggagctagggagatcttcctctggctctgctttcgctccctatgccggatctacagcgttcaccagcgcctcgccaggctacaattcccatctcccgtacagtgctgatgcggccgccgctgctactttcacctcttatgtgagctcaccttatgaccacacgacaggcatggccgggtctatagggtatcatccttatgctgctcccctgggctcgtacccgtatggagacccagcttaccgcaagaatgctacccgggacgccacagctactttgaaagcttggcttaacgagcaccggaaaaacccgtaccccaccaaaggcgagaagatcatgctggccatcatcactaaaatgaccctcactcaagtgtccacctggttcgccaacgccaggaggaggctaaaaaaggagaacaagatgacctggaccccacggaaccggagtgaagacgaggaggaggacgaaaacattgatctagagaaaaacgacgacgacgagccaaacaagcccacggacaagggagactccacagacacagagatcacaaactcatcaacccaggggaaataccatgcgacagatttaaagacgagactcattctaaagatcttgatccacctttgacagactcggaattaaaagaagcagaggagcggacggatttgctcgccgagcaagcgaaacccaccacatcctctccctccgttctacagagagggagtgatctcattacgcaagaaaagccctcagaaccgggccacgccgcgagcacgggaaacagcaacgtaacgtctgttattcattctcccccctcggcgcccaaacccaaactctggtctctggccgagatcgccacttcttcggacaggtgcaaagggagcagtgaggcttcacaggccgcgggtctgagtcaaagcacagtcattgccagcgctgcctcgccgacccggtcctcccctcagtgccctctccctaataacactgttctatctcggcctatttactacacgtcccctttttacccaggctacacgaactatagcactttcggacacctccacagcagtcatggcaccaacaccagctcaacggcacatttcaatggattaagccagactgttttaaacagagccgaggctctggtaagagagagcaaagtaagaagccaaacacaggtagatctttgtaaagactcaccttatgagctaaagaaaggtatgtcaaacatttaataccggattcatcgccaatcacacggacatttatttattatttgtggttgcctaaagaagaagcaaaagaagacgcattctgattttaaaaaatccgaggacaattattttctgagtaaatgcttatcctcaaaatcttagtttctgaatggttaatcaagaggatgtaatttctaagaattgtcttaaacgctgcagccgcctgagtctatttgtattaaagactaatatgtatatttaatgtagcattttgtatttaaaatggacaatacactatctttgaagtaaattatgaaaagaaaatg

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