LOCUS       NM_214714               2317 bp    mRNA    linear   VRT 27-FEB-2022
DEFINITION  Danio rerio SERPINE1 mRNA binding protein 1a (serbp1a), mRNA.
ACCESSION   NM_214714
VERSION     NM_214714.1
KEYWORDS    RefSeq.
SOURCE      Danio rerio (zebrafish)
  ORGANISM  Danio rerio
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Danionidae; Danioninae; Danio.
REFERENCE   1  (bases 1 to 2317)
  AUTHORS   Farnsworth DR, Posner M and Miller AC.
  TITLE     Single cell transcriptomics of the developing zebrafish lens and
            identification of putative controllers of lens development
  JOURNAL   Exp Eye Res 206, 108535 (2021)
   PUBMED   33705730
REFERENCE   2  (bases 1 to 2317)
  AUTHORS   Yan Y, He F, Li Z, Xu R, Li T, Su J, Liu X, Zhao M and Wu W.
  TITLE     The important role of apolipoprotein A-II in ezetimibe driven
            reduction of high cholesterol diet-induced atherosclerosis
  JOURNAL   Atherosclerosis 280, 99-108 (2019)
   PUBMED   30500605
REFERENCE   3  (bases 1 to 2317)
  AUTHORS   Dong X, Qiu X, Meng S, Xu H, Wu X and Yang M.
  TITLE     Proteomic profile and toxicity pathway analysis in zebrafish
            embryos exposed to bisphenol A and di-n-butyl phthalate at
            environmentally relevant levels
  JOURNAL   Chemosphere 193, 313-320 (2018)
   PUBMED   29145093
REFERENCE   4  (bases 1 to 2317)
  AUTHORS   Bayes A, Collins MO, Reig-Viader R, Gou G, Goulding D, Izquierdo A,
            Choudhary JS, Emes RD and Grant SG.
  TITLE     Evolution of complexity in the zebrafish synapse proteome
  JOURNAL   Nat Commun 8, 14613 (2017)
   PUBMED   28252024
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 2317)
  AUTHORS   Pasquier J, Cabau C, Nguyen T, Jouanno E, Severac D, Braasch I,
            Journot L, Pontarotti P, Klopp C, Postlethwait JH, Guiguen Y and
            Bobe J.
  TITLE     Gene evolution and gene expression after whole genome duplication
            in fish: the PhyloFish database
  JOURNAL   BMC Genomics 17, 368 (2016)
   PUBMED   27189481
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 2317)
  AUTHORS   Giousoh A, Vaz R, Bryson-Richardson RJ, Whisstock JC, Verkade H and
            Bird PI.
  TITLE     Bone morphogenetic protein/retinoic acid inducible neural-specific
            protein (brinp) expression during Danio rerio development
  JOURNAL   Gene Expr Patterns 18 (1-2), 37-43 (2015)
   PUBMED   25981450
REFERENCE   7  (bases 1 to 2317)
  AUTHORS   Cuello S, Ximenez-Embun P, Ruppen I, Schonthaler HB, Ashman K,
            Madrid Y, Luque-Garcia JL and Camara C.
  TITLE     Analysis of protein expression in developmental toxicity induced by
            MeHg in zebrafish
  JOURNAL   Analyst 137 (22), 5302-5311 (2012)
   PUBMED   23014190
REFERENCE   8  (bases 1 to 2317)
  AUTHORS   Johnsen H and Andersen O.
  TITLE     Sex dimorphic expression of five dmrt genes identified in the
            Atlantic cod genome. The fish-specific dmrt2b diverged from dmrt2a
            before the fish whole-genome duplication
  JOURNAL   Gene 505 (2), 221-232 (2012)
   PUBMED   22749781
REFERENCE   9  (bases 1 to 2317)
  AUTHORS   Valencia CA, Bailey C and Liu R.
  TITLE     Novel zebrafish caspase-3 substrates
  JOURNAL   Biochem Biophys Res Commun 361 (2), 311-316 (2007)
   PUBMED   17643392
REFERENCE   10 (bases 1 to 2317)
  AUTHORS   Woods IG, Wilson C, Friedlander B, Chang P, Reyes DK, Nix R, Kelly
            PD, Chu F, Postlethwait JH and Talbot WS.
  TITLE     The zebrafish gene map defines ancestral vertebrate chromosomes
  JOURNAL   Genome Res 15 (9), 1307-1314 (2005)
   PUBMED   16109975
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC068350.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC068350.1, BC165318.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA3505370, SAMEA3505371
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..2317
                     /organism="Danio rerio"
                     /mol_type="mRNA"
                     /db_xref="taxon:7955"
                     /chromosome="6"
                     /map="6"
     gene            1..2317
                     /gene="serbp1a"
                     /gene_synonym="hm:zeh0245; PAI-RBP1; serbp1; wu:fa12d05;
                     wu:fb36e07; wu:fc16f12; wu:fj13e12; zgc:55489"
                     /note="SERPINE1 mRNA binding protein 1a"
                     /db_xref="GeneID:335449"
                     /db_xref="ZFIN:ZDB-GENE-030131-7389"
     exon            1..329
                     /gene="serbp1a"
                     /gene_synonym="hm:zeh0245; PAI-RBP1; serbp1; wu:fa12d05;
                     wu:fb36e07; wu:fc16f12; wu:fj13e12; zgc:55489"
                     /inference="alignment:Splign:2.1.0"
     misc_feature    59..61
                     /gene="serbp1a"
                     /gene_synonym="hm:zeh0245; PAI-RBP1; serbp1; wu:fa12d05;
                     wu:fb36e07; wu:fc16f12; wu:fj13e12; zgc:55489"
                     /note="upstream in-frame stop codon"
     CDS             74..1249
                     /gene="serbp1a"
                     /gene_synonym="hm:zeh0245; PAI-RBP1; serbp1; wu:fa12d05;
                     wu:fb36e07; wu:fc16f12; wu:fj13e12; zgc:55489"
                     /note="PAI-1 mRNA-binding protein; SERPINE1 mRNA binding
                     protein 1"
                     /codon_start=1
                     /product="SERPINE1 mRNA binding protein 1a"
                     /protein_id="NP_999879.1"
                     /db_xref="GeneID:335449"
                     /db_xref="ZFIN:ZDB-GENE-030131-7389"
                     /translation="

MPGHLQEGFGCVVTNRFDQLFDDEEDPFEVLKQAEKKKKDATVPGAAKTAAQAAKQPKKESQKERRNPLPDKKEETQAPVPLKKDGMRKMGRRPEQQGQQGSQQQQQQQQVPQQQAGQGEGRPPADRRPDRRPPRERRFDKPADEKPAEGGEFSVEKTMGDRPFRGRGGPRGGRGGRGRGVGRTDGFDSRGKREFDRHSGSDRSLKAEEKRGGSGSHNWGTVKDELSELDQSNVTEDTPEGEEHPPADSENKENEVEEAKEEGPKEMSLDEWKAQQDKERAKVEFNIRKANEGADWKKGYVLHKSKAEDASADDAAGDHHFRKPANDITSQLEINFGDLGRPGRGRGGPRGGRGGRGAAAATRPPRERRPDKVGGVSVPNVDDPEAFPALA"

     misc_feature    86..>358
                     /gene="serbp1a"
                     /gene_synonym="hm:zeh0245; PAI-RBP1; serbp1; wu:fa12d05;
                     wu:fb36e07; wu:fc16f12; wu:fj13e12; zgc:55489"
                     /note="Intracellular hyaluronan-binding protein 4
                     N-terminal; Region: IHABP4_N; pfam16174"
                     /db_xref="CDD:465041"
     misc_feature    644..949
                     /gene="serbp1a"
                     /gene_synonym="hm:zeh0245; PAI-RBP1; serbp1; wu:fa12d05;
                     wu:fb36e07; wu:fc16f12; wu:fj13e12; zgc:55489"
                     /note="Hyaluronan / mRNA binding family; Region:
                     HABP4_PAI-RBP1; pfam04774"
                     /db_xref="CDD:461421"
     exon            330..543
                     /gene="serbp1a"
                     /gene_synonym="hm:zeh0245; PAI-RBP1; serbp1; wu:fa12d05;
                     wu:fb36e07; wu:fc16f12; wu:fj13e12; zgc:55489"
                     /inference="alignment:Splign:2.1.0"
     exon            544..684
                     /gene="serbp1a"
                     /gene_synonym="hm:zeh0245; PAI-RBP1; serbp1; wu:fa12d05;
                     wu:fb36e07; wu:fc16f12; wu:fj13e12; zgc:55489"
                     /inference="alignment:Splign:2.1.0"
     exon            685..753
                     /gene="serbp1a"
                     /gene_synonym="hm:zeh0245; PAI-RBP1; serbp1; wu:fa12d05;
                     wu:fb36e07; wu:fc16f12; wu:fj13e12; zgc:55489"
                     /inference="alignment:Splign:2.1.0"
     exon            754..828
                     /gene="serbp1a"
                     /gene_synonym="hm:zeh0245; PAI-RBP1; serbp1; wu:fa12d05;
                     wu:fb36e07; wu:fc16f12; wu:fj13e12; zgc:55489"
                     /inference="alignment:Splign:2.1.0"
     exon            829..1000
                     /gene="serbp1a"
                     /gene_synonym="hm:zeh0245; PAI-RBP1; serbp1; wu:fa12d05;
                     wu:fb36e07; wu:fc16f12; wu:fj13e12; zgc:55489"
                     /inference="alignment:Splign:2.1.0"
     exon            1001..1189
                     /gene="serbp1a"
                     /gene_synonym="hm:zeh0245; PAI-RBP1; serbp1; wu:fa12d05;
                     wu:fb36e07; wu:fc16f12; wu:fj13e12; zgc:55489"
                     /inference="alignment:Splign:2.1.0"
     exon            1190..2273
                     /gene="serbp1a"
                     /gene_synonym="hm:zeh0245; PAI-RBP1; serbp1; wu:fa12d05;
                     wu:fb36e07; wu:fc16f12; wu:fj13e12; zgc:55489"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      

gtggcatctagcagcgaagtgctcgctcaagccccgtagaatcggaggagaatcctgctgaaagggggccatcatgcccggacatctgcaagaaggtttcggctgtgtcgtaaccaatcggttcgaccagctatttgatgacgaagaggatccgttcgaggtgttaaagcaggcagaaaagaagaagaaggacgcgaccgtccctggtgccgcaaagaccgccgcgcaggctgctaagcagcccaaaaaggagtcgcagaaggagaggagaaacccgcttcccgataaaaaggaagaaacacaagcccccgttcctctcaagaaagatggcatgaggaagatgggccgccggcctgagcagcagggtcaacaaggatcccagcagcagcagcagcaacagcaggtgcctcagcagcaggcaggacagggggagggtcgtccaccagcagacaggcggcctgacaggaggccaccacgtgaacgacgctttgacaaacccgctgatgaaaaacctgctgagggtggagaattctcagttgagaagactatgggtgacaggccattccggggtcgtggaggtccccgaggggggcgcggagggcgaggcagaggtgttggcaggactgacggctttgactcgcgcggcaaacgagagtttgacagacacagcggcagcgaccgatccctgaaagcagaggagaaacgtggaggcagtggatctcataactggggcactgttaaggatgagttgagtgagcttgaccaatcaaacgtcaccgaggacacccctgaaggagaagaacacccacctgctgactcggagaacaaggagaatgaggttgaagaagcaaaagaagaaggccctaaggagatgtctctggatgaatggaaggcccagcaggataaagagagagccaaagtggaattcaacattcgtaaggcaaatgagggagctgactggaagaaaggatacgttctgcacaagtccaaggctgaggatgcctctgctgatgatgctgctggtgaccatcacttccgcaaacctgctaatgacatcacgtcccagctggagattaactttggagatctgggccgcccgggacgtggtcgtggaggtccacgaggtggcagaggtggccgtggggcggctgctgctaccagaccacctcgtgaacgcaggccagacaaggtcggaggagtgtctgtccctaacgtggacgacccagaggctttcccagccctggcttaagctgcacagacagctcttggctcacccaggaggatcactcctccatgggtccttgtctaaaaggcttgcatgctaacggattcttcagcagatgaaatgatggaagactgtcatccatgccattcacccttgaggactgaattttacctgttttagaaaaaaagaaggaaaattaaaaaaacaaaaacaaacaaaaaaaaaacaacggacggacttcttgctgttatgaagcaaattattggtcgaggttttgtatttagacaaggtagcagggatgttttcatacagtgtttcttttattgtttctttcttttgtttttcttttcagaaatgatgcattgttcatggatacgttttgtactgctgcttgaaaatatgcatttccaaaaatgggtgtcaagagcgcaccagtttatcttaaggtgtcccgtagcttgcttgctttttacacacaaatgccttgaaacaggggccgcccttttcagggatgtgatctaccggttagtcttttaatttttaaaggttactgcgtttctaagggaattatagagcattttagttctggtattaaacacctcccttccctgaaagcaaggctttagaaccgtaaaatcattttgattaaatgtacaatttctgattcagaccttaaagctgggatgtaattcaaatgatttttttattgaatgaccactgtaagcttcaaatggtgtctttgatgccattgcctctggtaactcaggatagtatcgtacttgttacgcgaagttctggtgtaaatacaacaagcaagtttacacaccgcactcctgtttactgattaatgtaagccaggttatggataaatcctgttagaaatgatgttttctttctgccccattgcttttacaacagctctactgcatacttgatctgaaagaaaccccttcctgttcagcgtggaacagctgagtgctattataatgtgtgaattcctaccctgctattagacctctgtcaataattaaaagatggtcgattcataaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaa

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