LOCUS       NM_131770                809 bp    mRNA    linear   VRT 15-APR-2024
DEFINITION  Danio rerio claudin 1 (cldn1), mRNA.
ACCESSION   NM_131770
VERSION     NM_131770.1
KEYWORDS    RefSeq.
SOURCE      Danio rerio (zebrafish)
  ORGANISM  Danio rerio
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Danionidae; Danioninae; Danio.
REFERENCE   1  (bases 1 to 809)
  AUTHORS   Liu,Y., Zhu,D., Liu,J., Sun,X., Gao,F., Duan,H., Dong,L., Wang,X.
            and Wu,C.
  TITLE     Pediococcus pentosaceus PR-1 modulates high-fat-died-induced
            alterations in gut microbiota, inflammation, and lipid metabolism
            in zebrafish
  JOURNAL   Front Nutr 10, 1087703 (2023)
   PUBMED   36819708
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 809)
  AUTHORS   Osorio-Mendez,D., Miller,A., Begeman,I.J., Kurth,A., Hagle,R.,
            Rolph,D., Dickson,A.L., Chen,C.H., Halloran,M., Poss,K.D. and
            Kang,J.
  TITLE     Voltage-gated sodium channel scn8a is required for innervation and
            regeneration of amputated adult zebrafish fins
  JOURNAL   Proc Natl Acad Sci U S A 119 (28), e2200342119 (2022)
   PUBMED   35867745
REFERENCE   3  (bases 1 to 809)
  AUTHORS   Piccione,M., Facchinello,N., Schrenk,S., Gasparella,M., Pathak,S.,
            Ammar,R.M., Rabini,S., Dalla Valle,L. and Di Liddo,R.
  TITLE     STW 5 Herbal Preparation Modulates Wnt3a and Claudin 1 Gene
            Expression in Zebrafish IBS-like Model
  JOURNAL   Pharmaceuticals (Basel) 14 (12), 1234 (2021)
   PUBMED   34959635
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 809)
  AUTHORS   Garcia-Concejo,A. and Larhammar,D.
  TITLE     Protein kinase C family evolution in jawed vertebrates
  JOURNAL   Dev Biol 479, 77-90 (2021)
   PUBMED   34329618
REFERENCE   5  (bases 1 to 809)
  AUTHORS   Hou,Y., Lee,H.J., Chen,Y., Ge,J., Osman,F.O.I., McAdow,A.R.,
            Mokalled,M.H., Johnson,S.L., Zhao,G. and Wang,T.
  TITLE     Cellular diversity of the regenerating caudal fin
  JOURNAL   Sci Adv 6 (33), eaba2084 (2020)
   PUBMED   32851162
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 809)
  AUTHORS   Clelland,E.S. and Kelly,S.P.
  TITLE     Exogenous GDF9 but not Activin A, BMP15 or TGFbeta alters tight
            junction protein transcript abundance in zebrafish ovarian
            follicles
  JOURNAL   Gen Comp Endocrinol 171 (2), 211-217 (2011)
   PUBMED   21291886
REFERENCE   7  (bases 1 to 809)
  AUTHORS   Clelland,E.S. and Kelly,S.P.
  TITLE     Tight junction proteins in zebrafish ovarian follicles: stage
            specific mRNA abundance and response to 17beta-estradiol, human
            chorionic gonadotropin, and maturation inducing hormone
  JOURNAL   Gen Comp Endocrinol 168 (3), 388-400 (2010)
   PUBMED   20553723
REFERENCE   8  (bases 1 to 809)
  AUTHORS   Xie,J., Farage,E., Sugimoto,M. and Anand-Apte,B.
  TITLE     A novel transgenic zebrafish model for blood-brain and
            blood-retinal barrier development
  JOURNAL   BMC Dev Biol 10, 76 (2010)
   PUBMED   20653957
  REMARK    Publication Status: Online-Only
REFERENCE   9  (bases 1 to 809)
  AUTHORS   Whitehead,G.G., Makino,S., Lien,C.L. and Keating,M.T.
  TITLE     fgf20 is essential for initiating zebrafish fin regeneration
  JOURNAL   Science 310 (5756), 1957-1960 (2005)
   PUBMED   16373575
REFERENCE   10 (bases 1 to 809)
  AUTHORS   Loh,Y.H., Christoffels,A., Brenner,S., Hunziker,W. and Venkatesh,B.
  TITLE     Extensive expansion of the claudin gene family in the teleost fish,
            Fugu rubripes
  JOURNAL   Genome Res 14 (7), 1248-1257 (2004)
   PUBMED   15197168
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AF359436.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF359436.1, BC097096.1 [ECO:0000332]
            RNAseq introns              :: mixed/partial sample support
                                           SAMEA2168446, SAMEA2168447
                                           [ECO:0000350]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..809
                     /organism="Danio rerio"
                     /mol_type="mRNA"
                     /db_xref="taxon:7955"
                     /chromosome="2"
                     /map="2"
     gene            1..809
                     /gene="cldn1"
                     /gene_synonym="cldn19"
                     /note="claudin 1"
                     /db_xref="GeneID:81590"
                     /db_xref="ZFIN:ZDB-GENE-010328-11"
     CDS             2..634
                     /gene="cldn1"
                     /gene_synonym="cldn19"
                     /note="claudin 19"
                     /codon_start=1
                     /product="claudin-1 precursor"
                     /protein_id="NP_571845.1"
                     /db_xref="GeneID:81590"
                     /db_xref="ZFIN:ZDB-GENE-010328-11"
                     /translation="

MAHAGLQMLGYCLGFLGLLGLIASTAMAEWKMSSYAGDNIITAQAQYEGLWQSCVSQSTGQLQCKKYDSLLKLPGEIQGARGLMLTGIFLCGLSTLVSFVGMKCTTCLSEAPQVKSKVALAGGVLFITGGLFALIATSWYGEKIRQKFFDPFTPTNARYEFGKALYVGWGSSALSIIGGSLLCCICGSEASEKPSYPPARAAGRPGTDRV"

     sig_peptide     2..85
                     /gene="cldn1"
                     /gene_synonym="cldn19"
                     /inference="COORDINATES: ab initio prediction:SignalP:6.0"
     misc_feature    71..547
                     /gene="cldn1"
                     /gene_synonym="cldn19"
                     /note="PMP-22/EMP/MP20/Claudin family; Region:
                     PMP22_Claudin; cl21598"
                     /db_xref="CDD:473919"
ORIGIN      

gatggcgcacgcagggctgcagatgctgggttactgtctgggttttctgggtctgctgggtctgatcgcctccacagccatggcggagtggaagatgtcctcgtacgccggggacaacatcatcacagcacaggcgcagtatgagggactgtggcagtcctgtgtgtcgcagagcaccggccagctgcagtgcaaaaaatacgactccctgctgaagctgccaggggagatccagggggctcgagggctgatgctgaccggcatcttcctgtgtggcctgtcgacgctggtgtctttcgtgggcatgaagtgcacaacctgcctttcagaagcgccacaggtgaagagtaaagtggctctggctggaggagtgctgttcatcactggagggctttttgctctgatcgccaccagctggtacggagagaagatccggcagaagttcttcgacccgtttactccaactaacgcgaggtatgagttcgggaaggctctgtatgtgggctggggctcttcagctctctccatcatcggcggttccctgctctgctgtatctgtgggagtgaagcttctgaaaaaccctcgtatcctccagcgcgcgcagcaggacgcccgggaactgaccgcgtctgaacacacacctgactgcaggcaaacctgcgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtttaatcttcgcctgttctcctgattaaccctctgcactgatgtaaatgaccggctcatcatgacgcactcattaaagctgaagtgtgtgtgttaaaaaaaaaaaaaaaaaaaa

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