LOCUS       NM_131768               1697 bp    mRNA    linear   VRT 26-DEC-2022
DEFINITION  Danio rerio claudin i (cldni), mRNA.
ACCESSION   NM_131768 XM_001332449 XM_692448
VERSION     NM_131768.2
KEYWORDS    RefSeq.
SOURCE      Danio rerio (zebrafish)
  ORGANISM  Danio rerio
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Danionidae; Danioninae; Danio.
REFERENCE   1  (bases 1 to 1697)
  AUTHORS   Metikala S, Casie Chetty S and Sumanas S.
  TITLE     Single-cell transcriptome analysis of the zebrafish embryonic trunk
  JOURNAL   PLoS One 16 (7), e0254024 (2021)
   PUBMED   34234366
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1697)
  AUTHORS   Langenbacher AD, Shimizu H, Hsu W, Zhao Y, Borges A, Koehler C and
            Chen JN.
  TITLE     Mitochondrial Calcium Uniporter Deficiency in Zebrafish Causes
            Cardiomyopathy With Arrhythmia
  JOURNAL   Front Physiol 11, 617492 (2020)
   PUBMED   33424641
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1697)
  AUTHORS   Hou Y, Lee HJ, Chen Y, Ge J, Osman FOI, McAdow AR, Mokalled MH,
            Johnson SL, Zhao G and Wang T.
  TITLE     Cellular diversity of the regenerating caudal fin
  JOURNAL   Sci Adv 6 (33), eaba2084 (2020)
   PUBMED   32851162
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 1697)
  AUTHORS   Zhang X, Zhou Q, Li X, Zou W and Hu X.
  TITLE     Integrating omics and traditional analyses to profile the
            synergistic toxicity of graphene oxide and triphenyl phosphate
  JOURNAL   Environ Pollut 263 (Pt A), 114473 (2020)
   PUBMED   33618456
REFERENCE   5  (bases 1 to 1697)
  AUTHORS   Solis CJ, Hamilton MK, Caruffo M, Garcia-Lopez JP, Navarrete P,
            Guillemin K and Feijoo CG.
  TITLE     Intestinal Inflammation Induced by Soybean Meal Ingestion Increases
            Intestinal Permeability and Neutrophil Turnover Independently of
            Microbiota in Zebrafish
  JOURNAL   Front Immunol 11, 1330 (2020)
   PUBMED   32793187
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 1697)
  AUTHORS   Gomez GA, Veldman MB, Zhao Y, Burgess S and Lin S.
  TITLE     Discovery and characterization of novel vascular and hematopoietic
            genes downstream of etsrp in zebrafish
  JOURNAL   PLoS One 4 (3), e4994 (2009)
   PUBMED   19308258
REFERENCE   7  (bases 1 to 1697)
  AUTHORS   Leung YF and Dowling JE.
  TITLE     Gene expression profiling of zebrafish embryonic retina
  JOURNAL   Zebrafish 2 (4), 269-283 (2005)
   PUBMED   18248185
REFERENCE   8  (bases 1 to 1697)
  AUTHORS   Malek RL, Sajadi H, Abraham J, Grundy MA and Gerhard GS.
  TITLE     The effects of temperature reduction on gene expression and
            oxidative stress in skeletal muscle from adult zebrafish
  JOURNAL   Comp Biochem Physiol C Toxicol Pharmacol 138 (3), 363-373 (2004)
   PUBMED   15533794
REFERENCE   9  (bases 1 to 1697)
  AUTHORS   Loh YH, Christoffels A, Brenner S, Hunziker W and Venkatesh B.
  TITLE     Extensive expansion of the claudin gene family in the teleost fish,
            Fugu rubripes
  JOURNAL   Genome Res 14 (7), 1248-1257 (2004)
   PUBMED   15197168
REFERENCE   10 (bases 1 to 1697)
  AUTHORS   Kollmar R, Nakamura SK, Kappler JA and Hudspeth AJ.
  TITLE     Expression and phylogeny of claudins in vertebrate primordia
  JOURNAL   Proc Natl Acad Sci U S A 98 (18), 10196-10201 (2001)
   PUBMED   11517306
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BX682556.5 and BX649554.17.
            
            On or before Nov 30, 2007 this sequence version replaced
            XM_001332449.1, XM_692448.2, NM_131768.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: GDQH01008730.1, AF359428.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA2168446, SAMEA2168447
                                           [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-113               BX682556.5         4857-4969           c
            114-246             BX682556.5         3285-3417           c
            247-1686            BX682556.5         1-1440              c
            1687-1697           BX649554.17        2001-2011
FEATURES             Location/Qualifiers
     source          1..1697
                     /organism="Danio rerio"
                     /mol_type="mRNA"
                     /strain="Tuebingen"
                     /db_xref="taxon:7955"
                     /chromosome="3"
                     /map="3"
     gene            1..1697
                     /gene="cldni"
                     /gene_synonym="b52b12; cldn32; etID38174.3; fb52b12;
                     wu:fb52b12"
                     /note="claudin i"
                     /db_xref="GeneID:569084"
                     /db_xref="ZFIN:ZDB-GENE-010328-9"
     exon            1..113
                     /gene="cldni"
                     /gene_synonym="b52b12; cldn32; etID38174.3; fb52b12;
                     wu:fb52b12"
                     /inference="alignment:Splign:2.1.0"
     misc_feature    109..111
                     /gene="cldni"
                     /gene_synonym="b52b12; cldn32; etID38174.3; fb52b12;
                     wu:fb52b12"
                     /note="upstream in-frame stop codon"
     exon            114..246
                     /gene="cldni"
                     /gene_synonym="b52b12; cldn32; etID38174.3; fb52b12;
                     wu:fb52b12"
                     /inference="alignment:Splign:2.1.0"
     CDS             115..750
                     /gene="cldni"
                     /gene_synonym="b52b12; cldn32; etID38174.3; fb52b12;
                     wu:fb52b12"
                     /codon_start=1
                     /product="claudin i"
                     /protein_id="NP_571843.1"
                     /db_xref="GeneID:569084"
                     /db_xref="ZFIN:ZDB-GENE-010328-9"
                     /translation="

MGSAGVQIVCVALGILGLIATVVTIAIPQWKTSAFIGQNIITAQVSEEGLWMQCVVQSTGQQQCKSYDSLLILSSDLQAARAMTIISCMLSVLSLLILCGGADFTTCIENEDVKPKVTLVSAIGLILAGLLVIIPVSWAANNVVRDFNNPMVPEAQKRELGPCIYIGWASGVLLILAGGLLCCFSRPRSSGSSGAAKYYSNSASAPSKNYV"

     misc_feature    115..657
                     /gene="cldni"
                     /gene_synonym="b52b12; cldn32; etID38174.3; fb52b12;
                     wu:fb52b12"
                     /note="PMP-22/EMP/MP20/Claudin family; Region:
                     PMP22_Claudin; cl21598"
                     /db_xref="CDD:473919"
     exon            247..1697
                     /gene="cldni"
                     /gene_synonym="b52b12; cldn32; etID38174.3; fb52b12;
                     wu:fb52b12"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      

acaggacgtaacggtttcacaaggtgggagactaacttcaagaaaaaaagtcaagagactaactacaaaaagcaggaaacttagagactttctacaaagagctgcaaataaaggatgggctccgctggtgtgcagattgtgtgtgtggctctgggaattttaggactcattgctacagtcgtgaccattgctattccacaatggaagacttctgcctttattggtcagaacatcatcactgcacaggtctcggaggagggtctgtggatgcagtgtgtggttcagagcaccggtcagcagcagtgtaaaagctacgactcgttgctcatcctgagctcagacctgcaggcggctcgagccatgaccatcataagctgcatgctgagcgtcctgtccctgctcatcctgtgcggcggtgcagacttcaccacctgcatcgaaaacgaagacgtcaagcccaaagtgaccctggtgtccgccatcggcctgatcctggcgggcctgctggtcatcatcccagtcagctgggccgccaacaacgtcgtgcgcgactttaacaacccgatggttcctgaggcacaaaagagggagctgggtccttgtatttacataggctgggcttcaggagtgctgctcatactggccgggggtctgctgtgctgcttcagcaggcctcgttccagcggatccagcggagccgccaaatactacagcaacagcgcctcagcgcccagcaaaaattatgtgtaaataaatgcaaaagatgagcatttaagatcattctaggtatagtacgtactagataacccgtctaaggtagcgaataagtctgtagtttgtaggaaaatcgccctcatacgacttaaccgtggtttatttacagtagcctatattaatcatgttttatttaagcaaaatttttacaaatgctgtgttaagttgtgtgttgtaaaaggttaccacatgaatttgttttgggtttgttttgttttatgtgatattttgtttctggcaaaaccatggttaattttggtgagagtggaactggaaaaggtcaaaatggagaaagatgtaaatattacttgtttggagtctctgaactgtcctacaaatactgtctttaagcattttaataatcagttttatatctttttttatgataatttactactgccttttcttagagctgctaataaacacaacttcagggatgggacagagcttgtgtccaaaatactttcattcaggtcactgtataacacatgtgtgccagtccttattattttcaaaaccatgactgcactcatttcttttgagtattaatgttgcataacagctactactagactgtgtttcagatgtattcctactagcgtttactcagtgtgtaatcagtttacttttggggtttttaatgagaccattttactttattatgtaatagacaatgttgtctttaaaaaatgtatgttgtaagaccagactaaggagtttaagtcactggtacttttcaaaaacatatttaggatatgggaaatactgtatcattttgtttttaatactgtataatttcgtgctttctttgtgcattaggtcataatcatttccactgtctgcctgttcaataaaaccgactgattcagacatttgtatgtgcgatcaattgttgacacatgaataaagctttgataaaataa

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