LOCUS       NM_001326439            3088 bp    mRNA    linear   VRT 16-OCT-2021
DEFINITION  Danio rerio tubulin polymerization-promoting protein family member
            2 (tppp2), mRNA.
ACCESSION   NM_001326439 XM_682834
VERSION     NM_001326439.1
KEYWORDS    RefSeq.
SOURCE      Danio rerio (zebrafish)
  ORGANISM  Danio rerio
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Danionidae; Danioninae; Danio.
REFERENCE   1  (bases 1 to 3088)
  AUTHORS   Bayes A, Collins MO, Reig-Viader R, Gou G, Goulding D, Izquierdo A,
            Choudhary JS, Emes RD and Grant SG.
  TITLE     Evolution of complexity in the zebrafish synapse proteome
  JOURNAL   Nat Commun 8, 14613 (2017)
   PUBMED   28252024
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3088)
  AUTHORS   Pasquier J, Cabau C, Nguyen T, Jouanno E, Severac D, Braasch I,
            Journot L, Pontarotti P, Klopp C, Postlethwait JH, Guiguen Y and
            Bobe J.
  TITLE     Gene evolution and gene expression after whole genome duplication
            in fish: the PhyloFish database
  JOURNAL   BMC Genomics 17, 368 (2016)
   PUBMED   27189481
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 3088)
  AUTHORS   Elkon R, Milon B, Morrison L, Shah M, Vijayakumar S, Racherla M,
            Leitch CC, Silipino L, Hadi S, Weiss-Gayet M, Barras E, Schmid CD,
            Ait-Lounis A, Barnes A, Song Y, Eisenman DJ, Eliyahu E, Frolenkov
            GI, Strome SE, Durand B, Zaghloul NA, Jones SM, Reith W and
            Hertzano R.
  TITLE     RFX transcription factors are essential for hearing in mice
  JOURNAL   Nat Commun 6, 8549 (2015)
   PUBMED   26469318
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 3088)
  AUTHORS   Orosz F.
  TITLE     On the tubulin polymerization promoting proteins of zebrafish
  JOURNAL   Biochem Biophys Res Commun 457 (3), 267-272 (2015)
   PUBMED   25576359
REFERENCE   5  (bases 1 to 3088)
  AUTHORS   Aoki M, Segawa H, Naito M and Okamoto H.
  TITLE     Identification of possible downstream genes required for the
            extension of peripheral axons in primary sensory neurons
  JOURNAL   Biochem Biophys Res Commun 445 (2), 357-362 (2014)
   PUBMED   24513284
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CR753866.9 and EH594009.1.
            
            On May 18, 2016 this sequence version replaced XM_682834.5.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: GDQH01030653.1, EH594009.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA2168446, SAMEA2168447
                                           [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-104               CR753866.9         21488-21591
            105-872             EH594009.1         77-844
            873-3088            CR753866.9         30293-32508
FEATURES             Location/Qualifiers
     source          1..3088
                     /organism="Danio rerio"
                     /mol_type="mRNA"
                     /strain="Tuebingen"
                     /db_xref="taxon:7955"
                     /chromosome="5"
                     /map="5"
     gene            1..3088
                     /gene="tppp2"
                     /note="tubulin polymerization-promoting protein family
                     member 2"
                     /db_xref="GeneID:559490"
                     /db_xref="ZFIN:ZDB-GENE-140106-24"
     exon            1..138
                     /gene="tppp2"
                     /inference="alignment:Splign:2.1.0"
     misc_feature    37..39
                     /gene="tppp2"
                     /note="upstream in-frame stop codon"
     exon            139..344
                     /gene="tppp2"
                     /inference="alignment:Splign:2.1.0"
     CDS             148..693
                     /gene="tppp2"
                     /note="tppp3l; zmp:0000001064"
                     /codon_start=1
                     /product="tubulin polymerization-promoting protein family
                     member 2"
                     /protein_id="NP_001313368.1"
                     /db_xref="GeneID:559490"
                     /db_xref="ZFIN:ZDB-GENE-140106-24"
                     /translation="

MAEGSGEISLGEVEMAFRKFAVHGDTKATGKEMNGKNFVKLCKDCKVIDGKNVTSTDVDIIFSKVKVKSARVITFEQFTQAMGELATKRFKGKSQEEAVQLLYGLIAGKEPTNIGVTKVAKASAVDRLTDTSKYTGSHKERFDESGKGKGREGRADIPDTSGYVSAYKGQGSYDSKVKEDE"

     misc_feature    187..654
                     /gene="tppp2"
                     /note="Region: p25-alpha; pfam05517"
                     /db_xref="CDD:461670"
     exon            345..498
                     /gene="tppp2"
                     /inference="alignment:Splign:2.1.0"
     exon            499..3088
                     /gene="tppp2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      

attctacacacacacacacacacgcatacacgcacttagaagaggcagacaggaagacggagcaacaacacacacccacattcagcatcctttcggagcagcttagcatcagcatccaagactgtccacctctgtcagatcggcagcatggctgagggttcgggtgaaatatcgctgggagaggttgagatggcatttcgtaaatttgcagttcatggagacaccaaagcgacggggaaggaaatgaacgggaaaaactttgttaagctgtgtaaagactgtaaggtcatcgatgggaaaaatgtcaccagcacagacgtagacatcatcttcagcaaagtcaaggttaaatcagcacgtgtcatcacatttgagcagttcactcaagccatgggcgaactggctacgaaacgttttaaagggaagagccaggaggaggcagtgcagctcctctatggcctcattgctggcaaagaaccaaccaacattggtgtcactaaagtggcaaaagcctcagccgtggataggttaacagacaccagcaagtacaccgggtctcataaggagcgttttgatgaatctggaaagggaaaaggccgcgagggaagggcggacatccctgacaccagtggatacgtctctgcatacaaaggccaaggcagctatgacagcaaagtaaaagaggacgaatgaatggatgaaaggggaggaatgcttaatgcatgacataatgtgtacgtctgaagtcttcctgctttaatttcggctgctaggtcttggcttgcctgcaaaagcaaacccctggcaaaaatcttgctcaataactgtaatctttttttcacttttatatctgcaattacttttcaaatataatatgctgctgttataaattataaataccctttcgtttgttatgacactggatcttttcgccatgtagcaacttgtctttctgtccaaacatgctagctgctacctcaaaaacactgatttaggtatgatggaatataactgatataaatacataccttgaatgcaagtcactttaaaagaaaactgtcaaatgtgtaaattagttaaatatgcaaaacaaaaacattccgttgaatataaaaaaaacagagttgttagggggttttacagtacattctgtcatcatgttagtgatttttcacgtggtagcaagcagtagggctgcacgattctgactaaaatgagattcgatcacgatttttttagcttaaaatcaagatcacaattttctcacaattctgtagataaaggctaatatgagtatgctattattattattttatctcaaatatatggtgaaacaacaacaaataatattaggcttgtgtgtaggtttgctgttggataaaatactaaaacttgtatagacatgcgatggtggattgaatagactttaaatttgtcctgtttgttaatttacagtaaagtgatgacatcagaatacaaatttttataattctaaagtttaaatattaggtttgagacatatgcttgtcatttgtcatggacaactatattagacatttttttactggtaaaatgagacatttgtcattatcaaattccctcttgcattttattcaacattatagcttctagagcacttgtaatgacactgtaaaacatttattctcatgcacaacactttgtgtttgctatgaaagaaaaaacacaccaaatgcttgtcgtaatcataactaaaatgtaatatatagttaaatgatgtgtgcagtttttgtttttaatttcaccgctgagtgcagctaatgtcatggctgccgtcgcatactgatttttagtgcatttcacatggctgttatcaagatttattgtataaggcattaactcttacggttgatgggatctggtctcaaaaatcagtatgcgagaagtacctgtatgacctgcttcttccagcgagattttgaagtgcgcatcgtatggacgctacgctatcccatgatgccctgtgagagaattcataaacgggagtgaagcgacacaactcaatgtgtcgatgacaaaatggcagatgtagtacatccgagtttcattcatactgctcacattcatactgtatagaacgtacttttctaatggccgagtagttcatttaaattcaaatgcacctactgagtactaggcattttcagacgcatctcgtgtgacccttttaaaaccatttggaggtgtccacattgctggaaaaagtatataaaacagtgtgaagacttgtgtgacctcctttatgcttctcccgtactttaaaatataattggctgaatcgctgctgaattaagattgtgtgagggggtcaaatcgagatcacaatcttttttagattaatcgtgcagccctaacaagctgttgtttttttcccatttgcctttcataaaatgtgcataatttataaatataaatgaaccaaaaattaacagttaaaggcatatttcatcccaaaatgaattattcagtctcacgttgttccaaaaatctattaaacacacacacaaaaaagatatatctgattctgccaaatggtcaatatattattattgtgatttgcacaaaaataacatcatataggtttgaaacaaattgacagacaaacaattttgtgtttaagaaacgtctaatagacatttaaacgtagacaacttggctaaaacaaggctaaacttgggctgtcagtgaaaatctaatagatctctaagaataggccaaaacaaatagatttgatacactttttttgtgttggcttctcattcttagacatctattagattttcactgacagcccaaatttagccatgttttagccaagatgaccatgtttagacatctgttagacatcttttaaaaacaaaacatgcttgcttggacttttcatttttggaatgaagtgtcattttaactgcttccttctttccacagaggtttatatacatgtgctggctatttgctgagctttattgtgtgctttttgagcttcttagctttgttgcaccgagatctctatcagactgaactgagtcaaataaagtccaataatgaa

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