LOCUS       NM_001080013            3640 bp    mRNA    linear   VRT 14-OCT-2021
DEFINITION  Danio rerio ADNP homeobox 2b (adnp2b), mRNA.
ACCESSION   NM_001080013 XM_687520
VERSION     NM_001080013.1
KEYWORDS    RefSeq.
SOURCE      Danio rerio (zebrafish)
  ORGANISM  Danio rerio
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Danionidae; Danioninae; Danio.
REFERENCE   1  (bases 1 to 3640)
  AUTHORS   Elkon R, Milon B, Morrison L, Shah M, Vijayakumar S, Racherla M,
            Leitch CC, Silipino L, Hadi S, Weiss-Gayet M, Barras E, Schmid CD,
            Ait-Lounis A, Barnes A, Song Y, Eisenman DJ, Eliyahu E, Frolenkov
            GI, Strome SE, Durand B, Zaghloul NA, Jones SM, Reith W and
            Hertzano R.
  TITLE     RFX transcription factors are essential for hearing in mice
  JOURNAL   Nat Commun 6, 8549 (2015)
   PUBMED   26469318
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3640)
  AUTHORS   Dresner E, Malishkevich A, Arviv C, Leibman Barak S, Alon S, Ofir
            R, Gothilf Y and Gozes I.
  TITLE     Novel evolutionary-conserved role for the activity-dependent
            neuroprotective protein (ADNP) family that is important for
            erythropoiesis
  JOURNAL   J Biol Chem 287 (48), 40173-40185 (2012)
   PUBMED   23071114
REFERENCE   3  (bases 1 to 3640)
  AUTHORS   Song HD, Sun XJ, Deng M, Zhang GW, Zhou Y, Wu XY, Sheng Y, Chen Y,
            Ruan Z, Jiang CL, Fan HY, Zon LI, Kanki JP, Liu TX, Look AT and
            Chen Z.
  TITLE     Hematopoietic gene expression profile in zebrafish kidney marrow
  JOURNAL   Proc Natl Acad Sci U S A 101 (46), 16240-16245 (2004)
   PUBMED   15520368
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC125828.1.
            
            On Mar 11, 2007 this sequence version replaced XM_687520.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC125828.1, DV584569.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA2168446, SAMEA2168447
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..3640
                     /organism="Danio rerio"
                     /mol_type="mRNA"
                     /strain="AB"
                     /db_xref="taxon:7955"
                     /chromosome="19"
                     /map="19"
     gene            1..3640
                     /gene="adnp2b"
                     /gene_synonym="si:ch211-129n15.3; wu:fc49c08; wu:fi26a03;
                     zgc:152871"
                     /note="ADNP homeobox 2b"
                     /db_xref="GeneID:564171"
                     /db_xref="ZFIN:ZDB-GENE-030131-5930"
     exon            1..181
                     /gene="adnp2b"
                     /gene_synonym="si:ch211-129n15.3; wu:fc49c08; wu:fi26a03;
                     zgc:152871"
                     /inference="alignment:Splign:2.1.0"
     misc_feature    177..179
                     /gene="adnp2b"
                     /gene_synonym="si:ch211-129n15.3; wu:fc49c08; wu:fi26a03;
                     zgc:152871"
                     /note="upstream in-frame stop codon"
     exon            182..299
                     /gene="adnp2b"
                     /gene_synonym="si:ch211-129n15.3; wu:fc49c08; wu:fi26a03;
                     zgc:152871"
                     /inference="alignment:Splign:2.1.0"
     CDS             192..3035
                     /gene="adnp2b"
                     /gene_synonym="si:ch211-129n15.3; wu:fc49c08; wu:fi26a03;
                     zgc:152871"
                     /codon_start=1
                     /product="activity-dependent neuroprotector homeobox
                     protein 2b"
                     /protein_id="NP_001073482.1"
                     /db_xref="GeneID:564171"
                     /db_xref="ZFIN:ZDB-GENE-030131-5930"
                     /translation="

MYQFPVKGLEKIRRTRRKVKNILGEFGLEACLNLGQELQEYYPGDNIFDATDWCNLSDGFDGRWRKKWGYRTQGLCCTLCNFSTRSWHTYKTHVQRYHDEEEHMCKLAACASCPFIAHPRLVCKHLKLFHNEDTKSETSAAPQLPPRAVNGTTFQCRRCHIQDTLLYSVKKHVLLYHYTSTLNKYAGQRTEQELVALGDRSQKFYCKKCYISAESSEHLLYHLLTSDKHKELDVHIRSLIFETDNKKQFPALAPKAQGPSPVMMMKDQPAATATLAAGGITGVENGGSAVIATPGTSQAFLPTQASALVQLASAEAKGLLRPGVPMGFQNTQMPRPALPPPPNSIPPNQMPVRVGLPNQAQLQPVSRQIVLPPGVRLNVPGVRPPTPQSFSANPRLPLNQPPSGGTMLTSQSLLSHLIPTGNKVDGLPTYTLAPLQVLSVQANNSQGVSKPQLPPSQNNPAAQQNKQSSGLSTPKQTKKWITCPICNELFPSDIYESHPEVHKEAAKLPKVGLAARAPFLKKMPDKTVKCLTCKILISEKGVFEHLLHGMNCLFCSGLFYSIKQLVDHIQIEHNVSRKSNCDFMRREYRLYTDDSGYLLFPYFDIRTTAPKLIMGEKELNLALVTSSLDLIFVKMLPNNPQGVNQQYTPCKMPTPKPDSTECPFCSEKLLNKECYHMHLKEKHFIVPTLHAILKTPSYRCLYCGGVYTGKTTTKAIIVHLAKCRSAPKSVRESDKLTLGLAVTPKANRAHGSYPAHPRQITGPTPTSAQASVPSTQPPESEAEMQSKMRLEIAFREAMEANRKEREERLARKRKLERDRLAGLTLPSPDIVVDPSVKLALDPAGMELRTFEDRREFVNKYFNTQPYPLKKEIIALSARLLLNKTDVACQISSKRTRCMKNIQKMKAVVLLGFNMTEVMKLKHDLLIPEIEPEKVATMADTDMEVDQE"

     misc_feature    192..2453
                     /gene="adnp2b"
                     /gene_synonym="si:ch211-129n15.3; wu:fc49c08; wu:fi26a03;
                     zgc:152871"
                     /note="Activity-dependent neuroprotector homeobox protein
                     N-terminal; Region: ADNP_N; pfam19627"
                     /db_xref="CDD:466132"
     exon            300..392
                     /gene="adnp2b"
                     /gene_synonym="si:ch211-129n15.3; wu:fc49c08; wu:fi26a03;
                     zgc:152871"
                     /inference="alignment:Splign:2.1.0"
     exon            393..3623
                     /gene="adnp2b"
                     /gene_synonym="si:ch211-129n15.3; wu:fc49c08; wu:fi26a03;
                     zgc:152871"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      

aatgcgccattttctcgactctaaacggcaagcacagtaaatgggtcctacttccaaattttaataaatacacttaatagctgatttccataactgagagcacagacttcttgttggaacatccttacatcgtctcaacatcctaactcgtcggttctggcagacacgcggattggtgaaagtgttgcaccatgtaccagtttccagtaaaaggtttggagaagatccgcagaacaaggcgaaaagtaaaaaatattcttggagaatttggacttgaagcatgtcttaatctgggccaagaactccaggaatattacccaggagacaatatttttgatgctacagactggtgcaatttgtcagatgggtttgatggccgatggagaaagaagtggggatatcggacacaaggattgtgctgcactttgtgtaatttctccacaaggtcttggcatacatacaaaacccatgttcagcgctaccacgatgaagaagagcacatgtgcaagcttgcagcctgtgcttcctgcccgtttatagcccaccccagattggtctgcaagcatctcaagttgttccacaatgaagatacaaagtcagagacatctgcagccccacagctgcctccaagagctgtgaatggcaccacatttcagtgccgaagatgtcatatacaagatactcttttgtacagcgtgaaaaagcatgttcttctatatcactacacttccacattaaataaatatgctggtcaaagaacggagcaggaacttgtggccctaggagaccggtctcagaagttctactgcaaaaagtgttacatatcggcggagtcatccgaacacttgctgtaccatcttctgacctcagataagcacaaggaactggatgtgcatatcagatctttaatttttgaaaccgataataagaaacagttcccagcacttgcaccaaaagcacaagggccttctcctgtcatgatgatgaaagatcagccagccgcgactgccacattggccgctggtggaattacaggagtggaaaatggtggttctgcagtcattgctactcctggaaccagccaggcatttcttccaactcaagcttctgctctcgttcagcttgctagtgctgaagcaaagggtttactgaggcctggagtcccaatgggttttcagaacacccaaatgcccagacctgctctacctcctcctcctaacagcattcctccaaaccagatgcctgtcagagtaggcctacctaaccaggcacaactacaaccagtttcacgccaaattgtcctaccaccaggtgttcggcttaacgtacctggtgttaggccaccaactcctcagtccttttctgctaatccaaggcttcctctaaatcagccaccctctggaggaaccatgctaacttctcaatctcttttgagccacttgatccccactggcaacaaagtcgacggcttgcccacctacacacttgcacctttgcaggtcctgtcagtccaggcaaataactcccaaggagtcagcaaaccacaattgcctccatcccagaacaatccagctgctcagcaaaacaaacaaagcagcggcttatcgacccccaagcaaaccaagaagtggatcacatgccctatttgtaatgaactcttcccatctgatatctacgagtcccatccagaggttcacaaagaggcagctaaattgcccaaggttggccttgctgctcgtgctccatttttgaaaaagatgccagacaagacggtgaaatgcctgacatgcaagatcctgatttcggaaaagggtgtctttgagcacctgcttcatggcatgaactgcttgttttgttcagggctcttctactccatcaagcaacttgtcgaccatatccagatagaacataatgtgtcccgaaagagcaactgtgatttcatgaggcgtgaatacagactgtatactgatgattcagggtatctgcttttcccttacttcgatatcaggaccacagctcctaaacttataatgggtgaaaaggagctcaatcttgcattggtcacaagctccctcgatttgatttttgtgaagatgttgcccaacaatccccagggtgttaaccagcagtacaccccatgcaagatgcctacacccaagcctgacagtacagagtgccccttctgctcggagaagcttctgaacaaagaatgctatcacatgcacctcaaagagaagcatttcattgtgcccactctgcatgctatacttaaaaccccatcctacagatgcctctactgtggtggtgtgtacactggaaaaaccaccaccaaggccatcattgtccatttggctaaatgccgcagtgcaccgaagagtgtcagagagagcgataaactgactttaggattggctgttactcctaaagcaaaccgagcacatggttcatacccggctcatccaagacagatcacaggtccaaccccaacttccgctcaagcttctgttccttccactcagccaccagaatcagaagcagagatgcagagtaagatgcgcctggaaatagccttcagagaagcaatggaggcgaatagaaaagagcgcgaggaacgattggcaagaaagagaaaacttgagcgagataggctggctggtctgaccctcccctcacctgatatagtagtcgatccttctgtaaaattagcattggatcctgccggaatggagttacgtacttttgaagatcgacgagagtttgtcaataagtatttcaacacccagccttaccctctcaagaaggagattattgccctgagtgcccgtttactgcttaacaaaactgacgttgcatgccagattagctcaaagcgcaccagatgcatgaagaacatacagaagatgaaggctgtggtacttctaggcttcaacatgacagaggtcatgaaactgaagcatgaccttctcatcccagagattgaaccagagaaggtggccacaatggcagatacagatatggaggttgaccaggagtagctttacagcactaatcaagacaaaaaaatgacttgcaatgcaagttttactaagagactgaattagtatgtgttccttgaaacaatgcaaaatatgttccattttcaccgaaactagtgttaaactgttaaccaagtcgaagatttaagcaggtaaaaatgcattgaattttgctgctgtttataatcttgtgaatacttaggttttgtttcatgttattcattttaaagtatacatgcattgtttttccactgatgtatcacttcaagtaggtccatttaaaaatagctgtttgtagcccatttatagttgtagggttgaatatgtttgtgatttatacttttcatatatgccaaacctcataaactatttttgtcatattttctttatatatttgtttgaatttaagagtttctaaacttaactgtttccacttttcttttagaccttgtatcctactgttaattaattcactttattgtcaaatttcatttatatcttgcttgccttatacttttataaatatgttatttctattattgtttcaaactgattttgtttcttttttgccaaaaatgtttcatataaaaaaaaaaaaaaaaaaa

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