LOCUS       NM_001040248            2893 bp    mRNA    linear   VRT 20-NOV-2022
DEFINITION  Danio rerio nuclear factor I/Xb (nfixb), mRNA.
ACCESSION   NM_001040248
VERSION     NM_001040248.1
KEYWORDS    RefSeq.
SOURCE      Danio rerio (zebrafish)
  ORGANISM  Danio rerio
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Danionidae; Danioninae; Danio.
REFERENCE   1  (bases 1 to 2893)
  AUTHORS   Kaaij LJ, Mokry M, Zhou M, Musheev M, Geeven G, Melquiond AS, de
            Jesus Domingues AM, de Laat W, Niehrs C, Smith AD and Ketting RF.
  TITLE     Enhancers reside in a unique epigenetic environment during early
            zebrafish development
  JOURNAL   Genome Biol 17 (1), 146 (2016)
   PUBMED   27381023
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2893)
  AUTHORS   Pasquier J, Cabau C, Nguyen T, Jouanno E, Severac D, Braasch I,
            Journot L, Pontarotti P, Klopp C, Postlethwait JH, Guiguen Y and
            Bobe J.
  TITLE     Gene evolution and gene expression after whole genome duplication
            in fish: the PhyloFish database
  JOURNAL   BMC Genomics 17, 368 (2016)
   PUBMED   27189481
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2893)
  AUTHORS   Elkon R, Milon B, Morrison L, Shah M, Vijayakumar S, Racherla M,
            Leitch CC, Silipino L, Hadi S, Weiss-Gayet M, Barras E, Schmid CD,
            Ait-Lounis A, Barnes A, Song Y, Eisenman DJ, Eliyahu E, Frolenkov
            GI, Strome SE, Durand B, Zaghloul NA, Jones SM, Reith W and
            Hertzano R.
  TITLE     RFX transcription factors are essential for hearing in mice
  JOURNAL   Nat Commun 6, 8549 (2015)
   PUBMED   26469318
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 2893)
  AUTHORS   Diotel N, Rodriguez Viales R, Armant O, Marz M, Ferg M, Rastegar S
            and Strahle U.
  TITLE     Comprehensive expression map of transcription regulators in the
            adult zebrafish telencephalon reveals distinct neurogenic niches
  JOURNAL   J Comp Neurol 523 (8), 1202-1221 (2015)
   PUBMED   25556858
REFERENCE   5  (bases 1 to 2893)
  AUTHORS   Armant O, Marz M, Schmidt R, Ferg M, Diotel N, Ertzer R, Bryne JC,
            Yang L, Baader I, Reischl M, Legradi J, Mikut R, Stemple D, van
            IJcken W, van der Sloot A, Lenhard B, Strahle U and Rastegar S.
  TITLE     Genome-wide, whole mount in situ analysis of transcriptional
            regulators in zebrafish embryos
  JOURNAL   Dev Biol 380 (2), 351-362 (2013)
   PUBMED   23684812
REFERENCE   6  (bases 1 to 2893)
  AUTHORS   Pistocchi A, Gaudenzi G, Foglia E, Monteverde S, Moreno-Fortuny A,
            Pianca A, Cossu G, Cotelli F and Messina G.
  TITLE     Conserved and divergent functions of Nfix in skeletal muscle
            development during vertebrate evolution
  JOURNAL   Development 140 (7), 1528-1536 (2013)
   PUBMED   23482488
  REMARK    Erratum:[Development. 2013 Jun;140(11):2443]
REFERENCE   7  (bases 1 to 2893)
  AUTHORS   Song HD, Sun XJ, Deng M, Zhang GW, Zhou Y, Wu XY, Sheng Y, Chen Y,
            Ruan Z, Jiang CL, Fan HY, Zon LI, Kanki JP, Liu TX, Look AT and
            Chen Z.
  TITLE     Hematopoietic gene expression profile in zebrafish kidney marrow
  JOURNAL   Proc Natl Acad Sci U S A 101 (46), 16240-16245 (2004)
   PUBMED   15520368
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC115305.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC115305.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA2168447, SAMEA4476743
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..2893
                     /organism="Danio rerio"
                     /mol_type="mRNA"
                     /db_xref="taxon:7955"
                     /chromosome="3"
                     /map="3"
     gene            1..2893
                     /gene="nfixb"
                     /gene_synonym="zgc:136878"
                     /note="nuclear factor I/Xb"
                     /db_xref="GeneID:678521"
                     /db_xref="ZFIN:ZDB-GENE-060421-5000"
     exon            1..121
                     /gene="nfixb"
                     /gene_synonym="zgc:136878"
                     /inference="alignment:Splign:2.1.0"
     CDS             119..1441
                     /gene="nfixb"
                     /gene_synonym="zgc:136878"
                     /codon_start=1
                     /product="nuclear factor I/Xb"
                     /protein_id="NP_001035338.1"
                     /db_xref="GeneID:678521"
                     /db_xref="ZFIN:ZDB-GENE-060421-5000"
                     /translation="

MATEPFLVNEDPSRGPGIPECFVVSDSYRDEFHPFIEALLPHVRAFSYTWFNLQARKRKYFKKHEKRMTKDEERAVKDELLGEKPEIKQKWASRLLAKLRKDIRPEFREDFVLTITGKKPPCCVLSNPDQKGKIRRIDCLRQADKVWRLDLVMVILFKGSPLESTDGERLVKSPQCSNHGLCVQPHHIGVSVKELDLYLAYFVHTPESGQSDNSNQQGEADIKPPPNGHLSFQDCFVTSGVWNVAELVRVSQTPVATATGPNFSLADLDSPGYYNINLGRRSITSTPSTSSNKRKSIDDSEMESPVDDVFYSGRSPAPGASQPSGWPNDVDAVQHHLASMQERKIKHESDGVQFPYHAGSPRASASSLHFPSPSLIQQSSPYFTHPTIRYHHHPGQDPLKEFVQFVCADGSGQASGQHTPRQAPQLPTGLSASDHGTTTF"

     misc_feature    203..316
                     /gene="nfixb"
                     /gene_synonym="zgc:136878"
                     /note="Nuclear factor I protein pre-N-terminus; Region:
                     NfI_DNAbd_pre-N; pfam10524"
                     /db_xref="CDD:463134"
     misc_feature    380..694
                     /gene="nfixb"
                     /gene_synonym="zgc:136878"
                     /note="MH1 domain; Region: MH1; pfam03165"
                     /db_xref="CDD:460833"
     misc_feature    815..>1369
                     /gene="nfixb"
                     /gene_synonym="zgc:136878"
                     /note="CTF/NF-I family transcription modulation region;
                     Region: CTF_NFI; pfam00859"
                     /db_xref="CDD:459967"
     exon            122..205
                     /gene="nfixb"
                     /gene_synonym="zgc:136878"
                     /inference="alignment:Splign:2.1.0"
     exon            206..737
                     /gene="nfixb"
                     /gene_synonym="zgc:136878"
                     /inference="alignment:Splign:2.1.0"
     exon            738..800
                     /gene="nfixb"
                     /gene_synonym="zgc:136878"
                     /inference="alignment:Splign:2.1.0"
     exon            801..875
                     /gene="nfixb"
                     /gene_synonym="zgc:136878"
                     /inference="alignment:Splign:2.1.0"
     exon            876..987
                     /gene="nfixb"
                     /gene_synonym="zgc:136878"
                     /inference="alignment:Splign:2.1.0"
     exon            988..1115
                     /gene="nfixb"
                     /gene_synonym="zgc:136878"
                     /inference="alignment:Splign:2.1.0"
     exon            1116..1190
                     /gene="nfixb"
                     /gene_synonym="zgc:136878"
                     /inference="alignment:Splign:2.1.0"
     exon            1191..1369
                     /gene="nfixb"
                     /gene_synonym="zgc:136878"
                     /inference="alignment:Splign:2.1.0"
     exon            1370..1461
                     /gene="nfixb"
                     /gene_synonym="zgc:136878"
                     /inference="alignment:Splign:2.1.0"
     exon            1462..2868
                     /gene="nfixb"
                     /gene_synonym="zgc:136878"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      

cgactcgtttgctgttcctctcccaccacgctcctttttttctgggcaaacttttctgtttttttctaaaggagtaaaatgggtctttgagactgttggcaatattccccgctccacaatggccaccgaaccgtttctggtgaacgaagacccttccagaggtcctgggataccagagtgcttcgtcgtgtctgattcctacagggatgaatttcatcccttcatcgaggctttgctgccacatgtccgtgcgttctcctatacctggttcaacctccaggcccgtaagcgcaaatacttcaaaaagcacgagaagcgcatgacgaaggatgaggagcgcgccgtcaaagacgaactcctgggcgagaagcccgagatcaagcagaagtgggcgtcccgtctgctcgccaagctccgcaaagacatccgccccgagttccgcgaggactttgtgctcaccatcacggggaagaagccgccgtgctgcgtgctctccaaccccgaccagaagggcaagatccgccgcatcgactgcctgcggcaagccgacaaggtctggcgcctggacctggtgatggttatcctgttcaagggaagcccgctggagagcacggatggagagaggctggtcaagtccccgcagtgctcaaaccacggcctctgcgtgcagccgcaccacatcggagtgtccgtcaaggaactggacctgtatctggcctacttcgtccacacgccagaatctggacaatcggataactccaaccagcaaggagaagcagacatcaagcctccgcccaatgggcacttaagtttccaggactgcttcgtgacgtcaggtgtgtggaacgtggcagagctggtccgtgtgtcacagacaccagttgccacagcgaccggacccaacttttctctggccgaccttgacagtccaggatactacaacattaacctgggtcgccgctccattacgtccacgccatcaaccagctccaacaagcgtaaatctattgatgacagtgagatggagagcccagtggacgatgtcttctactcgggtcgttctcctgccccgggagcgtctcagcccagcggctggcccaatgacgtcgatgcagtgcaacaccatttggccagtatgcaggagaggaagataaaacacgaatccgatggcgtgcagtttccttaccatgcaggaagtccccgcgcctctgcttcctccctgcacttcccctcaccctccctcatccagcagtccagcccgtacttcacccatcccaccatccgataccaccaccacccgggacaggacccgctcaaggagtttgtgcagtttgtgtgcgccgatggatctggacaggctagcggtcagcatactccacgccaggctccacagctcccaacaggtttgtcagcatcggatcacgggacaacaactttctgaacatcccccagcagacgcagtcatggttcctttgacgaggtcctgcctgcaacctgtcgacacaatttgaaagttttcttttttgacaaaaaaaaaatcctgtttgaaaattccctcccacccgaaacgcaccctacgagacgtgagcagaatttgattgggaaacgttcgagcatgtatttgccaaccgtcagacgcccttcaaacccacatgagcagctccgctaaagactgtcagatcaccggcggaggaaacagacggactgacacacacaaactacagcatctgatctacagagacactaaatcatactagcaacaaggatgtagtgtacaatggccaggattttcaacagtttcagtggtgaggattcagacacaacaaacacgcaagatttgtactcgatcccttatattttgtttgtaatcaaaacacttaaacgtgctgacattcagcaaacaggcgacactaaaattcactagacgtttcacatttatagcgggtgaaacgtctgtttaatgttcccttcttcagtcaattcataaactaactacgaaaagcaggagtattgcactacaaatatgagaagaacactagattgacgtgcactattgatcaacggcggacattatttgcacattagattgcggagaaaaacgaacacgcgctacaaactacccagagatgcttctgaaaggacgtcctcatttttaggccttgaacaaaaatgttttgtcatttcaggcccttagccaactagatttttttagcactcctgtaggacagacaacgcacacatttaaggcacatttgtgagattttgtggctgttaaaggacctctgtttgctggtaatagtgcagtgatacactaaatcaaccaaattcactaagcaacagtcagtttctgttactttgaatgggatatatgcacagctagtgttaatcatctaatgataaacttctggtgaaagtctaatgtgacttttcataaggtttcttttacagcatcgatgttgtaatgtaattaaaatacactcagttaaatagactgaagcattgatttagtcaagcgtaaaacgatttgaaagattgttaggagcagctggcgagtgcaaaaactccattgaaaatactggggtaaaataaatgacatggcagggggaaatggattttaatgcagtgcttcttgtatggtttaagacccactttatatcgtacatcaatcaggcagtaaaaaaacactcatttttaaagaaatcagaccttaaacgtgacgattttataatggaaagactgttcaccggaagcgctgaggctggctgcctgaaatgaaatgtctgtgtgcatatacccctttgatgtgaactctactgaaggttttgctcaaactggattctattaaaacagaaacgatttcactcactaaaaaaaaaaaaaaaaaaaaaaaaaa

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