LOCUS       NM_001003782            1216 bp    mRNA    linear   VRT 05-OCT-2024
DEFINITION  Danio rerio septin 5b (septin5b), mRNA.
ACCESSION   NM_001003782 XM_696474
VERSION     NM_001003782.2
KEYWORDS    RefSeq.
SOURCE      Danio rerio (zebrafish)
  ORGANISM  Danio rerio
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Danionidae; Danioninae; Danio.
REFERENCE   1  (bases 1 to 1216)
  AUTHORS   Campbell,P.D., Lee,I., Thyme,S. and Granato,M.
  TITLE     Mitochondrial proteins encoded by the 22q11.2 neurodevelopmental
            locus regulate neural stem and progenitor cell proliferation
  JOURNAL   Mol Psychiatry 28 (9), 3769-3781 (2023)
   PUBMED   37794116
REFERENCE   2  (bases 1 to 1216)
  AUTHORS   Torraca,V., Bielecka,M.K., Gomes,M.C., Brokatzky,D.,
            Busch-Nentwich,E.M. and Mostowy,S.
  TITLE     Zebrafish null mutants of Sept6 and Sept15 are viable but more
            susceptible to Shigella infection
  JOURNAL   Cytoskeleton (Hoboken) 80 (7-8), 266-274 (2023)
   PUBMED   36855298
REFERENCE   3  (bases 1 to 1216)
  AUTHORS   van Leeuwen,L.M., Evans,R.J., Jim,K.K., Verboom,T., Fang,X.,
            Bojarczuk,A., Malicki,J., Johnston,S.A. and van der Sar,A.M.
  TITLE     A transgenic zebrafish model for the in vivo study of the blood and
            choroid plexus brain barriers using claudin 5
  JOURNAL   Biol Open 7 (2) (2018)
   PUBMED   29437557
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 1216)
  AUTHORS   Bayes,A., Collins,M.O., Reig-Viader,R., Gou,G., Goulding,D.,
            Izquierdo,A., Choudhary,J.S., Emes,R.D. and Grant,S.G.
  TITLE     Evolution of complexity in the zebrafish synapse proteome
  JOURNAL   Nat Commun 8, 14613 (2017)
   PUBMED   28252024
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 1216)
  AUTHORS   Helmprobst,F., Lillesaar,C. and Stigloher,C.
  TITLE     Expression of sept3, sept5a and sept5b in the Developing and Adult
            Nervous System of the Zebrafish (Danio rerio)
  JOURNAL   Front Neuroanat 11, 6 (2017)
   PUBMED   28261064
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 1216)
  AUTHORS   Pasquier,J., Cabau,C., Nguyen,T., Jouanno,E., Severac,D.,
            Braasch,I., Journot,L., Pontarotti,P., Klopp,C., Postlethwait,J.H.,
            Guiguen,Y. and Bobe,J.
  TITLE     Gene evolution and gene expression after whole genome duplication
            in fish: the PhyloFish database
  JOURNAL   BMC Genomics 17, 368 (2016)
   PUBMED   27189481
  REMARK    Publication Status: Online-Only
REFERENCE   7  (bases 1 to 1216)
  AUTHORS   Elkon,R., Milon,B., Morrison,L., Shah,M., Vijayakumar,S.,
            Racherla,M., Leitch,C.C., Silipino,L., Hadi,S., Weiss-Gayet,M.,
            Barras,E., Schmid,C.D., Ait-Lounis,A., Barnes,A., Song,Y.,
            Eisenman,D.J., Eliyahu,E., Frolenkov,G.I., Strome,S.E., Durand,B.,
            Zaghloul,N.A., Jones,S.M., Reith,W. and Hertzano,R.
  TITLE     RFX transcription factors are essential for hearing in mice
  JOURNAL   Nat Commun 6, 8549 (2015)
   PUBMED   26469318
  REMARK    Publication Status: Online-Only
REFERENCE   8  (bases 1 to 1216)
  AUTHORS   Guna,A., Butcher,N.J. and Bassett,A.S.
  TITLE     Comparative mapping of the 22q11.2 deletion region and the
            potential of simple model organisms
  JOURNAL   J Neurodev Disord 7 (1), 18 (2015)
   PUBMED   26137170
REFERENCE   9  (bases 1 to 1216)
  AUTHORS   Gomez,G., Lee,J.H., Veldman,M.B., Lu,J., Xiao,X. and Lin,S.
  TITLE     Identification of vascular and hematopoietic genes downstream of
            etsrp by deep sequencing in zebrafish
  JOURNAL   PLoS One 7 (3), e31658 (2012)
   PUBMED   22438865
REFERENCE   10 (bases 1 to 1216)
  AUTHORS   Cao,L., Ding,X., Yu,W., Yang,X., Shen,S. and Yu,L.
  TITLE     Phylogenetic and evolutionary analysis of the septin protein family
            in metazoan
  JOURNAL   FEBS Lett 581 (28), 5526-5532 (2007)
   PUBMED   17967425
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC078256.1.
            
            On Aug 31, 2012 this sequence version replaced NM_001003782.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC078256.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA3505371,
                                           SAMEA3505374 [ECO:0006172]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1216              BC078256.1         5-1220
FEATURES             Location/Qualifiers
     source          1..1216
                     /organism="Danio rerio"
                     /mol_type="mRNA"
                     /strain="Singapore"
                     /db_xref="taxon:7955"
                     /chromosome="10"
                     /map="10"
     gene            1..1216
                     /gene="septin5b"
                     /gene_synonym="sept5b; zgc:100950"
                     /note="septin 5b"
                     /db_xref="GeneID:445325"
                     /db_xref="ZFIN:ZDB-GENE-040808-43"
     exon            1..57
                     /gene="septin5b"
                     /gene_synonym="sept5b; zgc:100950"
                     /inference="alignment:Splign:2.1.0"
     CDS             15..1124
                     /gene="septin5b"
                     /gene_synonym="sept5b; zgc:100950"
                     /codon_start=1
                     /product="septin 5b"
                     /protein_id="NP_001003782.1"
                     /db_xref="GeneID:445325"
                     /db_xref="ZFIN:ZDB-GENE-040808-43"
                     /translation="

MTSSARYKSRTVKSEDGEEKEYVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTLINSLFLTDLYKDRKLLNAEERISQTVEIIKHTVDIEEKGVKLKLTIVDTPGFGDAVNNTESWRTITDYIEQQFEQYFRDESGLNRKNIQDNRVHCCLYFISPFGHGLRPVDVEFMKALQDKVNIVPLISKADCLTPAEMRKMKDRVREEIEKFGIKVYQFPDCDSDEDEEPKQQDRELKESTPFAVIGSNTIVEVKGQRVRGRLYPWGIVEVENQSHCDFVKLRNMLIRSHMHDLKDITCDAHYENYRAQCIQQMTSKLTQDNRVESPIPILPLSTPDVETEKLIKMKDEELRRMQEMLQKMQQQMHEQDL"

     misc_feature    132..947
                     /gene="septin5b"
                     /gene_synonym="sept5b; zgc:100950"
                     /note="Region: Septin; pfam00735"
                     /db_xref="CDD:395596"
     misc_feature    159..182
                     /gene="septin5b"
                     /gene_synonym="sept5b; zgc:100950"
                     /note="G1 box; other site"
                     /db_xref="CDD:206649"
     misc_feature    order(165..185,330..332,339..341,573..578,582..584,
                     750..755)
                     /gene="septin5b"
                     /gene_synonym="sept5b; zgc:100950"
                     /note="GTP/Mg2+ binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:206649"
     misc_feature    255..281
                     /gene="septin5b"
                     /gene_synonym="sept5b; zgc:100950"
                     /note="Switch I region; other site"
                     /db_xref="CDD:206649"
     misc_feature    261..263
                     /gene="septin5b"
                     /gene_synonym="sept5b; zgc:100950"
                     /note="G2 box; other site"
                     /db_xref="CDD:206649"
     misc_feature    330..341
                     /gene="septin5b"
                     /gene_synonym="sept5b; zgc:100950"
                     /note="G3 box; other site"
                     /db_xref="CDD:206649"
     misc_feature    order(336..443,444..473)
                     /gene="septin5b"
                     /gene_synonym="sept5b; zgc:100950"
                     /note="Switch II region; other site"
                     /db_xref="CDD:206649"
     misc_feature    573..584
                     /gene="septin5b"
                     /gene_synonym="sept5b; zgc:100950"
                     /note="G4 box; other site"
                     /db_xref="CDD:206649"
     misc_feature    750..758
                     /gene="septin5b"
                     /gene_synonym="sept5b; zgc:100950"
                     /note="G5 box; other site"
                     /db_xref="CDD:206649"
     exon            58..68
                     /gene="septin5b"
                     /gene_synonym="sept5b; zgc:100950"
                     /inference="alignment:Splign:2.1.0"
     exon            69..159
                     /gene="septin5b"
                     /gene_synonym="sept5b; zgc:100950"
                     /inference="alignment:Splign:2.1.0"
     exon            160..246
                     /gene="septin5b"
                     /gene_synonym="sept5b; zgc:100950"
                     /inference="alignment:Splign:2.1.0"
     exon            247..370
                     /gene="septin5b"
                     /gene_synonym="sept5b; zgc:100950"
                     /inference="alignment:Splign:2.1.0"
     exon            371..505
                     /gene="septin5b"
                     /gene_synonym="sept5b; zgc:100950"
                     /inference="alignment:Splign:2.1.0"
     exon            506..623
                     /gene="septin5b"
                     /gene_synonym="sept5b; zgc:100950"
                     /inference="alignment:Splign:2.1.0"
     exon            624..725
                     /gene="septin5b"
                     /gene_synonym="sept5b; zgc:100950"
                     /inference="alignment:Splign:2.1.0"
     exon            726..822
                     /gene="septin5b"
                     /gene_synonym="sept5b; zgc:100950"
                     /inference="alignment:Splign:2.1.0"
     exon            823..958
                     /gene="septin5b"
                     /gene_synonym="sept5b; zgc:100950"
                     /inference="alignment:Splign:2.1.0"
     exon            959..1061
                     /gene="septin5b"
                     /gene_synonym="sept5b; zgc:100950"
                     /inference="alignment:Splign:2.1.0"
     exon            1062..1195
                     /gene="septin5b"
                     /gene_synonym="sept5b; zgc:100950"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      

ggaaagcggccgggatgacgagcagcgccaggtacaagagcaggacggtgaaatcagaggatggagaggagaaagagtatgtgggtttcgccacactccccaatcaggttcacaggaagtcggtgaagaaagggtttgatttcacgctcatggtggcaggagagtctggcttagggaaatccacactgatcaacagcttgttcctcacagacctgtacaaggaccgcaagctgctgaacgctgaagagcgcatcagccagacggtggagatcatcaaacacacggtggacatcgaggagaaaggagtcaagctcaaactcaccatcgtggacactccgggtttcggagacgccgtcaataacacagagagctggaggaccatcactgactacatcgagcagcagtttgagcagtatttccgggacgagagcggcttgaacaggaagaacatccaggataatcgtgttcactgctgcttatacttcatctctccctttggacacgggctgcggccggtggatgtggagtttatgaaggctctgcaggacaaggtgaacatcgtaccgctcatttccaaggccgactgtctgacgccggcggagatgaggaagatgaaggacagggtgagggaggagatcgagaagttcggcattaaagtttatcagtttccagactgtgattcagacgaggacgaagagccgaagcagcaggaccgagagctgaaggaaagcactccatttgctgtgattgggagcaacactattgtcgaggtcaaaggtcagcgggtgagagggagactttacccatggggcatcgtggaagtggagaatcagtctcattgtgatttcgtcaagctgaggaacatgttgattcgctcacacatgcacgacctgaaggacatcacatgcgacgctcactacgagaactacagagcgcagtgcattcagcagatgaccagcaagctgacgcaggataatcgtgtggagagtcccatcccgatcctgcctctgtccacccctgatgtagaaacagagaaactgatcaagatgaaggatgaggagttgcggaggatgcaggagatgcttcagaagatgcaacagcagatgcacgagcaggacctgtgaaaacactcaccctttaaccacaagcagacactcaacactttaacacacactgaaggatgtggaggaggaaaaaaaaaaaaaaaaaaaaaaaa

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