LOCUS       XM_072319829            3650 bp    mRNA    linear   INV 19-MAR-2025
DEFINITION  PREDICTED: Diadema setosum protein argonaute-2-like (LOC140240018),
            mRNA.
ACCESSION   XM_072319829
VERSION     XM_072319829.1
DBLINK      BioProject: PRJNA1234140
KEYWORDS    RefSeq.
SOURCE      Diadema setosum
  ORGANISM  Diadema setosum
            Eukaryota; Metazoa; Echinodermata; Eleutherozoa; Echinozoa;
            Echinoidea; Euechinoidea; Acroechinoidea; Diadematoida;
            Diadematidae; Diadema.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_092700) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_964275005.1-RS_2025_03
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 03/17/2025
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3650
                     /organism="Diadema setosum"
                     /mol_type="mRNA"
                     /db_xref="taxon:31175"
                     /chromosome="16"
     gene            1..3650
                     /gene="LOC140240018"
                     /note="protein argonaute-2-like; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 22
                     Proteins"
                     /db_xref="GeneID:140240018"
     CDS             112..2841
                     /gene="LOC140240018"
                     /codon_start=1
                     /product="protein argonaute-2-like"
                     /protein_id="XP_072175930.1"
                     /db_xref="GeneID:140240018"
                     /translation="

MYQPPVPPNFPYYGVPQFPPGQGQNPGQPPFPPPFTPPQPPQPPPGPNPQPTSTELVAMPRRPGFGQDGRPIALRANHFQVKIPPLDLYHYDVTITPEKCPRRINRDVIDTLVNAYKGRYFQNNLPVFDGRKNMYCKEQIPIEREKVELEVTLPGEGKDRIFKANIKYEGKVSLSLLESALKGEVVQIPYDAVQALDVIMRHLPSLRYTPVGRSFFSPPEEYSHPLGGGREVWFGFHQSIRPSMWKMMLNIDVSATAFYSCQSVIDFLCEVLDIQDISDQRRPLSDSHRVKFTKEIKGLKIEITHCGNMKRKYRVCNVTKRSAQTQTFPWQLENGQTVECTVAKYFRDRHNLILQYPHLPCLQVGQEQRHTYLPLEVCNIVAGQRCIKKLTDLQTSTMIKATARSAPDREKEIKNLVQKANFNNDQYVRQFGLSISNEMVTIEGRVLPAPKIQYGGKLNKPQQAIPNQGVWDMRGKQFHFGVEIEVWAIACFAPQHQCREEALRNFTLQLQKISNDAGMPIKWQPCFCKYAVGADQVEPMFRHLKKNFPKLQLIIVVLPGKTPVYAEVKRVGDTLLGIATQCVQVKNVNRTTAQTLSNLCLKINVKLGGVNNILAPNIRPRIFNEPVIFCGADVTHPPAGDDKKPSIAAVVGSMDGHPSRYCASVRIQTHRVEIIQDLMLMVKELLIQFYRSTGYKPARIIMYRDGVSEGQFLQVLANEMNAIRDACRSLEEGYEPGITFIVVQKRHHTRLFCAERREQIGRSGNIPAGTTVDSGITHPLEYDFYLCSHAGIQGTSRPSHYHVLWDDNGFRADELQCLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVEKEHDRYDHDSVQSSANSNGGDGSHHGRDGFGRTQKEMAMAIKVHDDTLKVMYFA"

     misc_feature    319..711
                     /gene="LOC140240018"
                     /note="N-terminal domain of argonaute; Region: ArgoN;
                     pfam16486"
                     /db_xref="CDD:465134"
     misc_feature    739..888
                     /gene="LOC140240018"
                     /note="Argonaute linker 1 domain; Region: ArgoL1;
                     pfam08699"
                     /db_xref="CDD:462567"
     misc_feature    895..1254
                     /gene="LOC140240018"
                     /note="PAZ domain, argonaute_like subfamily. Argonaute is
                     part of the RNA-induced silencing complex (RISC), and is
                     an endonuclease that plays a key role in the RNA
                     interference pathway. The PAZ domain has been named after
                     the proteins Piwi,Argonaut, and Zwille; Region:
                     PAZ_argonaute_like; cd02846"
                     /db_xref="CDD:239212"
     misc_feature    order(1048..1050,1093..1095,1135..1137,1147..1149,
                     1201..1203,1222..1224,1228..1230)
                     /gene="LOC140240018"
                     /note="nucleic acid-binding interface [nucleotide
                     binding]; other site"
                     /db_xref="CDD:239212"
     misc_feature    1387..2670
                     /gene="LOC140240018"
                     /note="PIWI domain, Argonaute-like subfamily. Argonaute is
                     the central component of the RNA-induced silencing complex
                     (RISC) and related complexes. The PIWI domain is the
                     C-terminal portion of Argonaute and consists of two
                     subdomains, one of which provides the...; Region:
                     Piwi_ago-like; cd04657"
                     /db_xref="CDD:240015"
     misc_feature    order(1804..1806,1816..1818,1852..1863,1870..1872,
                     1894..1896,1903..1905,1915..1917,1927..1929)
                     /gene="LOC140240018"
                     /note="5' RNA guide strand anchoring site [active]"
                     /db_xref="CDD:240015"
     misc_feature    order(2008..2010,2014..2016,2224..2226,2638..2640)
                     /gene="LOC140240018"
                     /note="active site"
                     /db_xref="CDD:240015"
ORIGIN      

gtcgggacgtgcaagaagcaacgattaaagtaatgatgaagtaaacgacggattttggcttcttttgcctctgtagtgaatcagtttacacaggaaatttacacaagggacatgtatcaaccgccagttccaccaaatttcccgtattatggggtgccccagtttcctccgggccagggccaaaacccaggccagccccctttcccgccccctttcacccctccccagccccctcagcccccgccggggccgaatccgcagcccacctcgaccgaactcgttgccatgccgaggagaccgggcttcggccaggacgggcggcccatcgcactgcgtgctaatcacttccaggtgaagatcccgcccctcgacctctaccactatgatgtcacaatcacgccagagaaatgccccaggagaatcaacagagatgtgattgacacactggtcaatgcctacaaggggcggtacttccagaacaacctaccggtcttcgatgggaggaaaaacatgtactgcaaggagcagattcctattgagagggagaaggtggagcttgaggtgaccctcccaggcgagggcaaggacagaatattcaaggccaacatcaagtatgaaggcaaggtcagcctctccctgctggagtccgccctcaagggagaggtggtccagatcccctatgacgctgtccaggccctggacgtcattatgagacacctgccatccctcaggtataccccggtgggtcgttccttcttttccccaccggaggaatactcacatcccctgggagggggcagggaggtgtggtttggttttcaccagagcatccgcccctccatgtggaagatgatgctgaacattgacgtctctgccactgcattctacagctgccagtctgtgattgacttcctctgcgaagttctcgacatccaggacatctcagatcagcggcgccctctctcggattcccacagggtcaagttcaccaaggagatcaaaggtctgaagattgagatcactcactgcggaaacatgaagcgcaagtatagagtgtgtaatgtcaccaagagatcggctcagactcagacgtttccctggcaacttgaaaatgggcaaaccgtggaatgcacagtggccaagtatttccgggacagacataatctcattttgcaataccctcaccttccctgtctgcaggttggacaggagcagcgccacacatacctacctctggaggtttgcaatatagttgccggacagcgctgtatcaagaagctaacagacctgcagacgtccaccatgatcaaggctactgcccggtcagcacctgacagggaaaaggaaatcaagaacctggtacaaaaggccaacttcaacaacgaccagtacgtccggcagtttggcctcagcatcagcaacgagatggtgaccatcgagggtagagtgctccccgcccccaagatccagtacggaggaaagctgaacaagcctcagcaggccattcccaaccaaggggtgtgggacatgaggggcaagcagttccactttggggtagagatagaagtctgggccatcgcctgcttcgcaccacaacaccagtgccgggaagaagccctcaggaatttcaccctccagctccagaagatttccaacgacgcggggatgccgatcaagtggcagccatgcttctgcaagtacgccgtgggcgctgaccaggtggagccgatgttcaggcacctcaagaagaacttccccaagctgcagctcatcatcgtggtcctgcccggaaagacgcctgtctatgctgaagtgaagcgggtcggcgacacactgctgggaatcgccacccagtgcgtccaggtcaagaacgtgaaccggacgacagcgcagaccctctccaacctctgcctcaagatcaacgtcaagcttggaggagtcaacaacattctggcgccaaacatcagaccgcgtatttttaacgagccggtcatcttttgcggagcagatgtaactcacccccccgctggtgacgataagaaaccctccattgccgccgtggtaggcagcatggacggccaccccagccggtactgcgccagcgtgcggatccagacccaccgggtggagatcatccaggacctgatgctgatggtaaaggagctcctcatccagttctaccgctccactggctacaagccagcccggatcatcatgtaccgggacggcgtcagcgagggacagttccttcaggtgctggccaatgagatgaatgccattcgggatgcctgtcgttcattggaggagggttacgagccaggcatcaccttcatcgtggtgcagaagagacatcacaccagactcttctgtgcagagaggagggaacagattgggagaagcggtaacatcccagccgggacgacggtagacagcggcatcactcacccactggagtacgacttctatctctgcagccacgccggtatccagggcacgagtcgtccctcccactaccacgtcctgtgggacgacaacggattcagggcggatgagctccagtgtctgacctaccagctgtgccacacctacgtccgctgcacccgaagcgtctccatccccgcccctgcctactacgcccacctcgtggccttccgcgcccgctaccacctcgttgagaaggaacacgaccgctacgaccacgacagtgttcagtccagcgctaatagcaatggcggggacggcagccaccatggaagggacggcttcggcaggactcagaaggagatggccatggcgatcaaggtccacgacgacacgctcaaggtcatgtactttgcctgagcttgtcggaggtcggaggtcgcagagggcgatgcgtaggcacatggcagcctagcagggggcatctcggcaagagaaaatatcatggcaagcatctaaacagaatttttgaaaaaacaaaacaagacagaagacgggccacagcaattgctgacgagatgaggtggagcccgggatattatattattgccagatttagtcaaagatgacaccacgttcacgtcgcacaacacgaaataaatggtggcatgaatgtgcactttttactcttcttcttcccatttcatatctcacctagtaaatgtaccaagcacacataatatgcattctgtagcatttttcttgttgtttttgtcgacaccgtcgtgttccttgttgtcgcggaagggtggtattcactgtaaagttgagtcgtcacaaaaataatacatctgccagctctgtagtagggcataatctcaccatccctttattcttgcttttctcttcacttaagtctgtctatagttacagaagagtcgcattgttatattacttccgtaccggaaagctgtggcatacgttagcccacgtaggtctgtgttttgatctacgttacttgctcttatgaagtattggtgttcccgagatgtagatgcttctgaagatttgtaagctcgggaaagagacaatgtcacgaataaattacgaatcagagctaggcaagtcaacactgctattaagacagatctcaagtagttgtgacaagatggctaatatgactcgtgagagcaatgatttgtgtgtttctgtaggtgtgtcaagtccac

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