LOCUS       XM_072298837            3505 bp    mRNA    linear   INV 18-MAR-2025
DEFINITION  PREDICTED: Bemisia tabaci Argonaute 2 (AGO2), mRNA.
ACCESSION   XM_072298837
VERSION     XM_072298837.1
DBLINK      BioProject: PRJNA1235222
KEYWORDS    RefSeq.
SOURCE      Bemisia tabaci
  ORGANISM  Bemisia tabaci
            Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
            Pterygota; Neoptera; Paraneoptera; Hemiptera; Sternorrhyncha;
            Aleyrodoidea; Aleyrodidae; Aleyrodinae; Bemisia.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_092795) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_918797505.1-RS_2025_03
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 03/12/2025
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3505
                     /organism="Bemisia tabaci"
                     /mol_type="mRNA"
                     /db_xref="taxon:7038"
                     /chromosome="3"
     gene            1..3505
                     /gene="AGO2"
                     /note="Argonaute 2; Derived by automated computational
                     analysis using gene prediction method: Gnomon. Supporting
                     evidence includes similarity to: 29 Proteins"
                     /db_xref="GeneID:109033070"
     CDS             778..3279
                     /gene="AGO2"
                     /codon_start=1
                     /product="protein argonaute-2"
                     /protein_id="XP_072154938.1"
                     /db_xref="GeneID:109033070"
                     /translation="

MRDPKQEFKKGNRKVLDVNLLPLNLNKLCEWIFHYDIATDPERPKRLLREVVDKFIKKHFPTFRPAFDGKKNLYTSKPLPFPGNRNVLEDTISVTNLEKPFDNVIEFRVAIKLAQKINTSEIKKFLNSKGTPHNVALPQSAIQAIDVILRAAPLASRALPIVPVGRNFFIEDRPRIVSLGGGLELWNGFYQSAILNWKPFLNIDVAHKGFPEPKPLIELYQEVCGIQSLDQTPYPIQKDRFRGFVTTLQIDYSLPGNSSSKRTHRIIGIGKCTRDLRFPLKDDGPEISVDEYFRTVKNYRIKYSNLPTVQVDPAAKNIYLPMELCSLKSGQVLHRKLDEKQTAVMVRKAAQPPEVRKEKILRAIQMAKYNQSPVVKDFGIEVNETMASVDARILETPSVEYAKPKQIIPRLGVWNAGEFLRSQALSNWFILNLDTSGRFPTKRSQLDKLCDELIRQGKAVGMVLRNPAGIVDLDTRDFKLVKSKIINLFKEWKENHAELVVVVLPDRGGQYYSMVKQCAELNVGILTQCLKSSTVQKRVNSATCKNILSKLNAKTNGVNHIVPAIHRPPVLQDPVMFVGIDVTHPSPDQTSIPSVAAVSASHDAKAFQYNMIWRLQNPREEIVRDLKNIIKEQLEFFHKKTGYKPEKIIVYRDGVGEGMFQQVLAAELTAIREACKEMPGEDYNPGITFLVVQKRHHVRFFPRQDIADQKTGNVPPGTIVDTEITHPRELDFYLVSHASLQGTARPTKYHRLWDDNDILEDELEKLTYYLCYLFTRCTRSVSYPAPTYYAHLAAFRARAYLENNPFRLQELEEFAKKNKIEENFLMASPMFFV"

     misc_feature    979..1224
                     /gene="AGO2"
                     /note="N-terminal domain of argonaute; Region: ArgoN;
                     pfam16486"
                     /db_xref="CDD:465134"
     misc_feature    1264..1413
                     /gene="AGO2"
                     /note="Argonaute linker 1 domain; Region: ArgoL1;
                     pfam08699"
                     /db_xref="CDD:462567"
     misc_feature    <1558..1758
                     /gene="AGO2"
                     /note="PAZ domain, argonaute_like subfamily. Argonaute is
                     part of the RNA-induced silencing complex (RISC), and is
                     an endonuclease that plays a key role in the RNA
                     interference pathway. The PAZ domain has been named after
                     the proteins Piwi,Argonaut, and Zwille; Region:
                     PAZ_argonaute_like; cd02846"
                     /db_xref="CDD:239212"
     misc_feature    order(1567..1569,1609..1611,1642..1644,1654..1656,
                     1708..1710,1729..1731,1735..1737)
                     /gene="AGO2"
                     /note="nucleic acid-binding interface [nucleotide
                     binding]; other site"
                     /db_xref="CDD:239212"
     misc_feature    1894..3180
                     /gene="AGO2"
                     /note="PIWI domain, Argonaute-like subfamily. Argonaute is
                     the central component of the RNA-induced silencing complex
                     (RISC) and related complexes. The PIWI domain is the
                     C-terminal portion of Argonaute and consists of two
                     subdomains, one of which provides the...; Region:
                     Piwi_ago-like; cd04657"
                     /db_xref="CDD:240015"
     misc_feature    order(2311..2313,2323..2325,2359..2370,2377..2379,
                     2404..2406,2413..2415,2425..2427,2437..2439)
                     /gene="AGO2"
                     /note="5' RNA guide strand anchoring site [active]"
                     /db_xref="CDD:240015"
     misc_feature    order(2518..2520,2524..2526,2734..2736,3148..3150)
                     /gene="AGO2"
                     /note="active site"
                     /db_xref="CDD:240015"
     polyA_site      3505
                     /gene="AGO2"
                     /experiment="COORDINATES: polyA evidence [ECO:0006239]"
ORIGIN      

gacattacgaatgaactacaattaattactgatctctaacacctgtggctatttcaatgtcttgcagggaagaaaagtgaaagcgggcctgaagcagggcaagccgtcagtggtccgtctggccaacctgataagaagcctttctctctctccagtgctggcgaaggttcgtcttcaagcattgcacatgaagagttgcctggaggcaccttgcagaagaaagtttcggacctgagggtgtcggataccccgcccgtaaaaggcactgttttgcagagccaaccaaaaaataaacatcaaaaaagtacaggatttcaacaaggacaacaacatccgcaaggacggatagacatacagcgtcctcgatccagtcagcaacggtggagacatcagtctcgtcaagagcctcaaagccagcatagttcacaagaaactcaaggtggacagccgccgcgaaagcaatttcatcagaaaaatcaacagcagatcaggagtgcgcctcccaatcagcctggttcccatcatcccgccagtagcggtgtgccttcttgggaattccagcagaatcaggtacctcaaaccgcacctctagctcaagtctcggcttgggctcaacctcgaaaaaatactgggaaaagtcaacaagctggaccggctcctcaaacaccttcctctcagtcaggaaaaactcgagaaacaaaaggggcaattcctaagcaggatgtgaaggatagaacccagcagacacacatactctctcaatcattcactatacctatgagagaccccaagcaggaattcaagaagggcaatcggaaagtacttgatgtcaacctgttacctttaaatcttaataagttatgcgagtggatatttcattatgacatcgcaacagatccggagcggcctaaaaggttgcttagggaagttgttgataaattcatcaaaaaacacttccctactttcagacctgcttttgacggcaagaaaaatttgtacacatccaaaccactaccttttccagggaataggaatgtgctcgaggatacaatttctgtgactaatttggaaaagccttttgataatgtaatagaatttcgtgttgccatcaagttggcacaaaagatcaacaccagtgaaatcaaaaagtttttgaactcaaaaggaacgccacataatgttgcattaccccagtcagccatccaagcgattgatgttattctgagagcagctcccttggcttcccgcgctcttcccatcgtgccagtgggcagaaactttttcattgaagacagaccaagaattgtctccctcgggggaggccttgagttgtggaatggcttttaccagtcagcaatattgaattggaaaccttttttgaatatcgatgttgctcataaaggtttccctgagcctaaacccttaattgaactttatcaagaagtttgtggcattcaaagtctggatcagactccttatccgattcaaaaagatcgattcagaggttttgtcacaacacttcaaatagactacagtttgcctggtaattcttcatccaaaagaacacatagaatcattggaattggaaagtgcacaagggatctccggtttccactaaaagatgatggccctgagatctcggtggatgagtattttagaactgtcaagaactacagaataaaatattcaaatttaccaacagttcaagtggaccctgcggccaagaatatttatcttcccatggaattatgctccttgaaaagtggccaagttttgcatcggaaattagatgaaaagcaaactgcggtgatggtcagaaaagcagctcaacctccagaggtgaggaaggagaaaatattgagagctatccaaatggcaaagtacaatcagagtcctgttgtgaaagattttgggattgaagtcaatgagacaatggcatcagttgacgcaagaatcttggagaccccctccgtggagtatgcaaaaccaaaacaaattataccaagattaggagtctggaatgctggagagtttttaaggtcccaagcactttcaaattggttcattttaaacttggatacctctggccgatttccaactaagcgtagccagttggataaattgtgtgatgaactgattcgtcaaggtaaagctgtaggaatggttctacgaaacccagctggtatagttgaccttgacactagagacttcaagcttgtaaaatcgaaaattatcaatctgtttaaagaatggaaagagaatcatgctgagctggtggtggttgtcttacccgatagaggtggtcaatattacagtatggtaaaacaatgcgctgagctcaacgtgggaattttaactcaatgtctcaagtcatcaacagtgcaaaaaagagtcaattctgctacctgcaaaaacattttatcgaaactcaatgccaaaactaatggtgtgaatcacatcgttcctgctattcacagaccccctgtccttcaggatcctgtcatgtttgttggaattgatgtcacccatccatcgccggaccaaacctccatcccgtccgtagcagcggtttcagcatctcacgatgccaaagcttttcagtacaatatgatctggcgactacagaatccacgtgaagaaattgtccgtgatctgaagaatatcataaaagagcaattggagttcttccataagaaaactggatacaagcctgagaaaataattgtgtatcgtgatggagtaggtgaaggcatgtttcaacaggtcttggcagcagagttaactgccatcagagaagcctgcaaagaaatgccaggggaagattacaaccctggcatcacatttttggttgtccaaaagcgccaccatgtccgttttttcccaagacaggatattgcagatcagaaaactggaaatgtgccaccaggcacgatcgtagatacagaaatcactcacccaagagaactagacttctacttggtgtctcatgcaagtttgcagggtacagccagaccaacaaaataccacagactttgggatgataatgatattctcgaggatgaattggagaagttgacgtattatttgtgctacttgttcactcgttgcactcgctcagtttcgtacccagcgcctacatactatgctcatcttgcagccttcagagctagagcatatttagagaacaacccatttcgtctgcaggaattagaggagtttgcaaaaaagaacaagatagaggaaaactttttgatggcgtcaccaatgttcttcgtttaaatattacctctgacttcaactttatcccaaaatattaatccaaatttcaattgatgttactttatcccattatatcaatccaaattctacttgatgttattttataccatcatattaatccgtttaatggatgttactttatgatccaaattttaattgaaattaatttgtaataccccaataatttaatattctttactcaatataatttttatgcctttgatga

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