LOCUS       XM_050172396           15033 bp    mRNA    linear   INV 19-MAR-2025
DEFINITION  PREDICTED: Dermacentor andersoni protein argonaute-1 (AGO1), mRNA.
ACCESSION   XM_050172396
VERSION     XM_050172396.3
DBLINK      BioProject: PRJNA1235765
KEYWORDS    RefSeq.
SOURCE      Dermacentor andersoni
  ORGANISM  Dermacentor andersoni
            Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida;
            Acari; Parasitiformes; Ixodida; Ixodoidea; Ixodidae;
            Rhipicephalinae; Dermacentor.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_092819) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Mar 19, 2025 this sequence version replaced XM_050172396.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_023375885.2-RS_2025_03
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 03/14/2025
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15033
                     /organism="Dermacentor andersoni"
                     /mol_type="mRNA"
                     /db_xref="taxon:34620"
                     /chromosome="6"
     gene            1..15033
                     /gene="AGO1"
                     /note="protein argonaute-1; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 138
                     Proteins"
                     /db_xref="GeneID:126524011"
                     /db_xref="VectorBase:DAND_012239"
     CDS             96..2849
                     /gene="AGO1"
                     /codon_start=1
                     /product="protein argonaute-2"
                     /protein_id="XP_050028353.1"
                     /db_xref="GeneID:126524011"
                     /db_xref="VectorBase:DAND_012239"
                     /translation="

MYPVGQPPGPPGGGGGGGGGGGPGGAPRAPPPVTPVGTVTPLGGGPVPLGPAPPATTPVAAVTAGALGPAEMAVAAAALPQFSCPRRPNVGTEGRPILLRANHFQISMPRGFLHHYDVTITPDKCPRKVNREIIETMVQSYSKIFGSQKPVFDGRKNMYTRDDLPLGKEKAELEVTLPGEGKDRVFRVAIKWVAQVSLYALEEVLEGRSRHIPMDAVQALDVVMRHLPSMTYTPVGRSFFSSPDGYFHPLGGGREVWFGFHQSVRPSQWKMMLNIDVSATAFYKAQPVIEFMCEVLELRDVNEQRKPLTDSQRVKFTKEIKGLKIEITHCGSMRRKYRVCNVTRRPAQLQSFPLQLENGQTVECTVAKYFLDKYKMKLRYPHLPCLQVGQEHKHTYLPLEVCNIVAGQRCIKKLTDMQTSTMIKATARSAPDREREINNLVRKADFNTDPYVQEFGLSISNTMMEVRGRILPPPKLQYGGRTKQQAIPNQGVWDMRGKQFHTGVEIRIWAIACFAPQRTCREDALRNFTQQLQKISNDAGMPIIGQPCFCKYATGPDQVEPMFRYLKSTFQGLQLVVVVLPGKTPVYAEVKRVGDTVLGMATQCVQAKNVNKTSPQTLSNLCLKINVKLGGINSILVPSIRPKVFNEPVIFLGADVTHPPAGDNKKPSIAAVVGSMDAHPSRYAATVRVQQHRQEIIQDLASMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFAQVLHHELLAVREACLKLEPDYKPGITFVVVQKRHHTRLFCSDKKEQIGKSGNIPAGTTVDLGITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNQFSADELQCLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVEKEHDSGEGSHQSSNGDDRTVVALARAVTIHPETLKVMYFA"

     misc_feature    378..767
                     /gene="AGO1"
                     /note="N-terminal domain of argonaute; Region: ArgoN;
                     pfam16486"
                     /db_xref="CDD:465134"
     misc_feature    795..947
                     /gene="AGO1"
                     /note="Argonaute linker 1 domain; Region: ArgoL1;
                     pfam08699"
                     /db_xref="CDD:462567"
     misc_feature    948..1310
                     /gene="AGO1"
                     /note="PAZ domain, argonaute_like subfamily. Argonaute is
                     part of the RNA-induced silencing complex (RISC), and is
                     an endonuclease that plays a key role in the RNA
                     interference pathway. The PAZ domain has been named after
                     the proteins Piwi,Argonaut, and Zwille; Region:
                     PAZ_argonaute_like; cd02846"
                     /db_xref="CDD:239212"
     misc_feature    order(1104..1106,1149..1151,1191..1193,1203..1205,
                     1257..1259,1278..1280,1284..1286)
                     /gene="AGO1"
                     /note="nucleic acid-binding interface [nucleotide
                     binding]; other site"
                     /db_xref="CDD:239212"
     misc_feature    1443..2720
                     /gene="AGO1"
                     /note="PIWI domain, Argonaute-like subfamily. Argonaute is
                     the central component of the RNA-induced silencing complex
                     (RISC) and related complexes. The PIWI domain is the
                     C-terminal portion of Argonaute and consists of two
                     subdomains, one of which provides the...; Region:
                     Piwi_ago-like; cd04657"
                     /db_xref="CDD:240015"
     misc_feature    order(1854..1856,1866..1868,1902..1913,1920..1922,
                     1944..1946,1953..1955,1965..1967,1977..1979)
                     /gene="AGO1"
                     /note="5' RNA guide strand anchoring site [active]"
                     /db_xref="CDD:240015"
     misc_feature    order(2058..2060,2064..2066,2274..2276,2688..2690)
                     /gene="AGO1"
                     /note="active site"
                     /db_xref="CDD:240015"
     polyA_site      15033
                     /gene="AGO1"
                     /experiment="COORDINATES: polyA evidence [ECO:0006239]"
ORIGIN      

tcgtgcgaatggattggcgtttgctttttcctcctcccccgatccaggctgcggtttgaaacagacagcttcgtgcagacagcacagaagcaaggatgtaccctgttggccagccccctgggccccctggcggtggtggcggcggaggaggaggtggtggcccgggaggggcgccgcgcgccccaccccccgtgactcccgtgggcacggtgacccccctagggggcggccccgtccctttgggtcccgcacccccagccacgacacccgtggctgctgtcacggcgggtgccctggggcccgccgagatggcggttgcagcggcggcactgccccaattctcgtgtccacggcgacccaacgtgggcaccgaggggcggccaatcctgctgcgggccaaccacttccagatctccatgccgcgtgggttcctgcaccactacgacgtcaccatcacgcctgacaagtgcccgcgcaaagtcaatcgggaaataatcgagacgatggtgcagtcctactcgaagatatttggcagccagaagcctgtgtttgacggtcgcaagaacatgtacacccgggacgacctgcccttgggcaaggagaaagcggagctggaggtgacccttcccggcgagggcaaggaccgtgtgttccgggtggccatcaagtgggttgcccaggtcagcctgtatgcactcgaggaagtgctcgagggacgctcccgccacatccccatggacgccgtccaggcactcgacgtggtcatgaggcacctgccctccatgacgtacacccccgttggccggtcgttcttctcgtcgccggacggctacttccacccgctgggtggtggccgcgaggtgtggttcggcttccaccagagtgtgcggccgagccagtggaagatgatgctcaacatcgacgtgtcggcgacggccttctataaggcgcagcctgtcatcgagttcatgtgcgaggtgctggagctgcgcgacgtcaacgagcagcgcaagcctctcacggactcccagcgcgtcaagttcaccaaggagatcaagggcctcaagattgagatcacccattgcggcagcatgcgccgcaagtaccgcgtctgcaatgtcacccgcaggcctgcccagctccagtcgtttccgttgcagttggagaatggccagacagtcgaatgtacagtggccaagtatttcctggacaagtacaaaatgaaactcaggtacccgcacctcccctgcctccaggtgggccaggagcacaagcacacctacctccccctcgaggtctgcaacatagtggctggccagaggtgcatcaagaagctcaccgacatgcagacatccaccatgatcaaggcaactgcgcggtccgccccggaccgggagcgcgagatcaacaatctggtgcgcaaggcggacttcaacacggacccgtatgtgcaggagtttggtctgtccatcagcaacactatgatggaggtcaggggccgcatcctgcctccgccaaagctgcagtatggcggccggaccaagcaacaggcgatccccaaccagggggtgtgggacatgcggggcaagcagttccacacgggcgtcgagatccgcatctgggccatcgcctgctttgcgccacagcgcacctgccgcgaggacgccctgcgcaacttcacccagcagctgcagaagatcagcaacgacgcgggcatgcccatcatcgggcagccctgcttctgcaagtatgccacgggccccgaccaggtcgagcccatgttccgatacctcaagtccaccttccaggggctccagcttgtcgtcgtcgtgctgcctggcaagaccccggtctacgccgaggtgaagcgagttggggacacggtgctgggcatggccacgcaatgcgtgcaggccaagaacgtcaacaagacgtccccacagactctgtccaacctgtgcctgaagatcaacgtcaagctgggtggcatcaattccatcctggtgcccagcatccggcctaaggtgttcaacgagccagtcatcttccttggtgccgacgtcactcatcctccggctggtgacaacaagaagccctccattgctgcggtggtgggcagcatggatgcgcaccccagccggtatgcggccacggtgcgggtgcagcagcaccgccaggagataatccaggacctggcatccatggtgcgtgagctgctcatccagttctacaagtcgacgcggttcaagccgacgcgcatcatcttctaccgagacggcgtctccgagggccagtttgcccaggtgctgcaccacgagctgctggcggtgcgcgaggcgtgcctcaagctcgagccagactataagccgggcatcacgtttgtcgtcgtccaaaagcggcaccacacgcgcctcttctgctccgacaagaaggagcagattggcaagagcggcaacatccccgcgggcaccacggtcgacctgggcatcacgcaccccaccgagttcgacttctacctctgctcgcatgcgggcatccaggggacgagccgcccgtcgcactaccacgtgctctgggacgacaaccagttctcggcggatgagctgcagtgcttgacctaccagctgtgccacacgtatgtgcgctgcacccgctccgtctccatccccgctccggcctactatgcgcacctggtggccttccgcgcccgataccacctcgtcgagaaagagcacgacagtggtgaaggcagccaccagtcgagcaatggggacgacaggacggttgtggcacttgcccgtgcagtcaccatccaccccgagaccctcaaggtcatgtacttcgcctgaggtggccccgcctccttccttgcgggcggctgacttgccccggccgcccagggcactgtgccggcgcgactcccactgcgtcccggctgggggaagacggggcaccaccagcgctacatcgcgaaggctgcgggagggcccggcattgcttgtcaatcagctgcggctccagtctcggcgctcctcggcgcgggaatgccgtccactgccaggctgaattaaagatgctgcgcaacatgctaattggcgacccgacaggtcgtgatcggcgacccgacaggtcttcatcggcgacccaaagggtctgatggtgcaacaggtgtggggcctctttgatactgcaggtggacaagagctgttaaccagaattttcagcgaaacctctccctgcattacctgcagagattatggccgtgtttgcagaaagaggcttagaaagtcctagctttttcttttaatgttgagggtgtagttgagtagctgcaagtatttttcaagcctgtggtggaacgcagactggatgcctctcaatgtatgttgaaacgattcgaaggcaggcttttcctcccagcttgtcagaggcattccacgccagctctgtcattaccgctgctgacagcgataccgcgaagcttccagtctgtccccaggtatgctgctcatgcaaataccacacgaggagtctcctccggggccctttcatattcaatctcttattgacctatggcatagttcatgcatattgcgatcattccattctttcctgctatctgcgtggatggtggggaggtagtttcttctgcacatttttcaaggggctgactgacagggcttaacttattagcctcgctcatttcatttgcaccactcgacatccacaggagcccccctcggttcccgtttttaatctgtcagtctgcatttgttctgccaatgcatcgtcaccatgacaacgttggtggagctctctcccaattgagcgaagcctctgctgggaatccagggcgcacgactcagtcgctttgtcgtggcgacatcttcataacttatgtggtgcccgaaaataccaaatagttgactatggtagctcgtattgttctagacttgctccctgcctgccattttctttgtgggtggcgttttggtttcccccatgtattcaacctttgttctttatggtgaccgggtcaagtctggaggtggcgtgcgatggtcacacaatccacccaaaatgtgttccaagcggcgggggggatggggggtacattaacattgcgaggctcctttggtgcagcagactgccgattatgggcactgttccacaagttgcctgggcatgctaaccagcttagcgcagcctccattgcggtatgtgggatgttcacccacttgaaagtgggtgagacttaaagatcctgtaattatacacatggttaccacatctgatgtggtaactgtgttcagacttttaaaagagggtagcaccagtaagctgcaagagaggttcattcaatgacagttagtgtgacccttgcaactggctttagtgtctgcgaactttggcacccaggcattgaagtggcgatagtgctttggcccagcggatgcctggcacagacgctgggtacttgctgctaaggacgatgccaggggttcatgagctgcaccgaggccctctcctccccgcctttccttccccagccagcctgcgttcctgacttggagctgcttgccactgtgggtgttttgcacagagtgtgtggcgcgtcagaacaattgtgtagtcgagggaaaacgtggaacttaagtagcgtatcatccgaatgcagtgtgaatgctcacaaaattaggaaattacataagctaacagttcattggagagcctctgctctattagcgagccaatggcaaatgtggatagttgacaactggtaaaattagaacaagctattttaaagctttttttttttatcttgcaagagcagaaaattcgcaggaatgttctgtgtgattgcagaacatgttcactatccaaatgagtataccggcatcaagtccgtaggggaaaagaagggggcagaaaaaaaaaatttctggaaaaaaaaaaagaacccgtagtaggaacagcgttctcagtgggtcgtgaaaccg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