LOCUS       XM_049769918            3593 bp    mRNA    linear   MAM 27-FEB-2023
DEFINITION  PREDICTED: Suncus etruscus NRDE-2, necessary for RNA interference,
            domain containing (NRDE2), mRNA.
ACCESSION   XM_049769918
VERSION     XM_049769918.1
DBLINK      BioProject: PRJNA862492
KEYWORDS    RefSeq.
SOURCE      Suncus etruscus (white-toothed pygmy shrew)
  ORGANISM  Suncus etruscus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Laurasiatheria; Eulipotyphla; Soricidae;
            Crocidurinae; Suncus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_064850) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_024139225.1-RS_2023_02
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 02/26/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3593
                     /organism="Suncus etruscus"
                     /mol_type="mRNA"
                     /isolate="mSunEtr1"
                     /db_xref="taxon:109475"
                     /chromosome="3"
                     /sex="male"
                     /tissue_type="lung fibroblast cultured cells"
                     /dev_stage="adult"
                     /country="USA: Madison, Wisconsin"
                     /lat_lon="43.072810 N 89.407550 W"
                     /collected_by="Susanne Meyer, Jessica Antosiewicz-Bourget"
     gene            1..3593
                     /gene="NRDE2"
                     /note="NRDE-2, necessary for RNA interference, domain
                     containing; Derived by automated computational analysis
                     using gene prediction method: Gnomon. Supporting evidence
                     includes similarity to: 3 Proteins"
                     /db_xref="GeneID:126003632"
     CDS             25..3528
                     /gene="NRDE2"
                     /codon_start=1
                     /product="nuclear exosome regulator NRDE2"
                     /protein_id="XP_049625875.1"
                     /db_xref="GeneID:126003632"
                     /translation="

MALFPAFAALSEAPDGGNSRKELDWLNNPSFCVGSSTSQSQTGEATAAASDRSPATRSPLISESADESDINKKHKQTSKKRKKEKKRKKKHQHQKKTRRRHSSSCSSGSEPDSDSGKDVFCRSGGTDVQAPENTSLGDTAATHPSGRLVWLEDAQALTGETFRLDKKPDRANWEYKSLYRGDIARYKRKGSSCLGLNPKKQCVSWEGTPREKKPAHKHSSERYFSRKNVSLLSIDGVALSPPGQPPAPATFIPLAGLEEASPPVTSWLNPLGIYDQATTQWLQGQGPPAKDSQEPDTQPDPESALLRAKVEDFNRRVRESPHDVQLWMDFVAFQDEVMRRPGLYTLQVDEEPRRRASLRMLVEKKLAIVERALESNQGSVELQLARLHLCAELQEPGALAKEWQKLIFLHPNDAALWQKYLRFSQSQFSTFSVSKLQGLYGKCLSTLSAVQDGSILSHPALPGTEQALFALFLQQCHFLRQAGHTEKAVSLFQAMVDFTFFKPDSVRELPTKGQVEFFEPFWDSGEPRAGEKGARGWKAWMHQQERGGWVIVTPDEEDDEADDDDQEIRDRTLPRWQIWLAAERSRDQRHWRPWRPEKNKKQTEEDCEDPERQVLFDDIGQSLIRLTQPELRFQLVAAFLQFLGLPCTARPPAACFYLALDDGGLFDGGFSDEQPLSAPYPPFSGVGYVGRMDPLGSRRGTRGHSREGEDFIRNLLHLLLPLFAGPERAQLCLSWLRFEVAKVLWCLHTKNKKRLKSRGKNCKKVAKSLLKEPENGSNFCLWRLYAHLEWLLGNTDDARKVFEVALGTAAGGRALQDGGLCELGLLYAELELELGLAPEPDSHGAATARAVQILTRLTETGPSTPSPSPVSAVPVLKARKAYEHALQACLGEAGAPASTPHALDRLASVAKCFMLFQYLTVGIEAAVRLHDQVAAQLRGAGSPAGAGLKDRCSSSHPSPVLEVLALMHTNLLRFHMKVSTYPLGPLRQALSEALKLFPDNQALWRAYVQVQNKSHSANKTRRFFDAVARSTKSLEPWLFAIEAEKMRKRLVETVQRVDGREVHATLPESGLTHRIRGLFESAVQSEDGEQCPLLWRMYLKFLVSLGNKERSKGVFYKALQNCPWAKALYMDAVEYFPDEIQEILDLMTEKELRVRLPLEELDLLLED"

     misc_feature    505..786
                     /gene="NRDE2"
                     /note="MTR4-interacting domain (MID) found in nuclear
                     exosome regulator NRDE2 and similar proteins; Region:
                     NRDE2_MID; cd22200"
                     /db_xref="CDD:412062"
     misc_feature    order(505..531,538..543,553..558,562..564,568..612,
                     619..627,631..639,661..669,682..687,691..696,703..723,
                     748..759,763..786)
                     /gene="NRDE2"
                     /note="MTR4 binding site [polypeptide binding]; other
                     site"
                     /db_xref="CDD:412062"
     misc_feature    961..1956
                     /gene="NRDE2"
                     /note="necessary for RNA interference; Region: NRDE-2;
                     pfam08424"
                     /db_xref="CDD:429988"
ORIGIN      

gctaccgcggtgcggcctgtcaccatggcgctattcccggcctttgcggcccttagtgaggctcccgacggtgggaattccaggaaagagttggactggctgaataacccaagcttctgtgttggaagctccacgtctcagagccaaactggagaggccacagccgctgcttcagacagatcgccagccaccagaagtcctctgatatcagagtcggcggatgaaagtgacattaataaaaagcacaaacaaacaagcaagaaaaggaagaaagagaagaagagaaagaagaagcatcagcaccagaagaaaacccggagaaggcacagctcatcctgcagcagcgggtctgagcctgacagtgactctgggaaggatgtcttttgccgcagtggtggcactgacgtccaggcccccgaaaacaccagcctgggagatactgcggccacccatcccagtgggcgcctcgtgtggctggaggatgctcaggccctgactggagagaccttccgcctggataagaagccagaccgtgccaactgggagtacaagtccctctaccgaggcgacatcgcaaggtacaagaggaaaggcagctcatgcctgggcctgaaccccaagaagcagtgcgtttcctgggaggggaccccccgtgagaagaagccggcacacaagcacagcagcgagcgctacttctctaggaagaacgtcagcctgctaagcatagatggtgtcgccctgagcccgcctggccagcctcccgccccggccaccttcatccctttggcaggcctggaagaggcctcccctcctgtgaccagctggctgaatcctctggggatctacgatcaggccaccacgcagtggctgcagggccaggggcccccggcgaaggactctcaggagcctgacacccagcccgaccctgagagcgccctcctcagggccaaggtggaggacttcaaccgcagggtgcgggagagcccgcatgacgtgcaactctggatggacttcgtggctttccaggatgaggtgatgcggcgccccggcctgtacacgctgcaggtggatgaggagcctcgccgtcgggcgtccctgcggatgctggtggagaagaagctggcgatcgtggagcgggcgctggaaagcaaccagggcagcgtggagctgcagctggcccgcctgcacctctgcgcagagctccaggagcccggcgcactcgccaaagagtggcagaagctcatcttcctgcaccccaatgacgctgccctctggcagaagtacctgcggttctctcagagccagttcagcaccttctccgtgtccaagctgcagggcctgtacggcaagtgcctgagcaccctgtcagctgtgcaagatgggagcatcctgtcacaccctgccctgcctggcaccgagcaggctctctttgctctctttcttcagcagtgccacttcctgcggcaggctggccacaccgagaaggctgtgtctctgttccaggccatggtagatttcaccttctttaagcccgacagcgtgcgggagctgcccaccaagggacaggtggagttctttgagcccttttgggacagtggcgagcccagagctggtgagaagggtgcccgaggctggaaggcatggatgcaccagcaggagcgtggtggctgggtgattgtgacgcctgatgaggaagatgacgaggcggacgatgatgaccaggagattcgggaccgaactctgccccggtggcagatctggcttgcagctgagcgctcccgggaccagagacactggcggccatggcgccctgagaagaacaagaagcaaactgaggaggactgcgaggatccagagaggcaggtattgtttgatgacattggtcagtctctgatccgcctgacccagcccgagctgcgcttccagctggtcgccgccttcctgcagttcctgggcctgccttgtaccgcccgcccacctgccgcctgtttctacctggctctggatgatggcggcctctttgacggcggcttctccgatgagcagccgctctcggcgccatacccgcccttctcaggtgtcggctatgtgggccgcatggacccgttgggcagccggcgggggacccggggccacagtcgtgagggtgaagatttcatccgtaacctcttgcaccttctgctgccactgtttgccggcccagagcgggcacaactctgcctttcctggctgcgctttgaggttgccaaggtcctctggtgcctgcacacaaagaacaagaagaggctgaagtctcgcgggaagaactgcaagaaagtagccaagagtctcctcaaggagccagaaaacggcagcaatttctgcctatggcgtctctacgcgcacctagagtggctgctgggcaacacagatgatgcccgcaaggtgtttgaggtggccctgggcacggcggccggtggccgggccctacaggacggcggcctctgcgaactcggtctgctgtacgctgagctggagctggagctggggctggcgccggagcccgactcacatggggcagccacagcccgtgcggtccagatcctcaccagactcaccgagacagggcccagtacgccctcccccagcccggtgtctgctgtgcccgtgctgaaggcacgaaaggcctatgagcacgcactgcaggcctgccttggggaggctggtgcccctgcgtccactccccatgccctggaccgcctggccagtgtggccaaatgcttcatgctcttccagtacctgactgtgggcattgaggcggccgtgaggctccacgaccaggtagcagcccagctgaggggtgcggggtcccctgctggtgcaggcctaaaggacaggtgcagttcctcacacccgagccctgtgctggaggtgctggcactgatgcacacgaacctgctgcggttccacatgaaggtcagcacgtacccactgggccccctgcgccaggcgctctccgaggccctgaaactcttcccggacaaccaggccctttggcgggcctacgtccaggttcagaataagtcccacagtgccaacaagaccaggagattcttcgatgccgttgccagatccaccaagtccttggagccctggctgttcgcgattgaagctgagaagatgaggaagaggctggtggaaaccgtgcagagggtggatggcagagaggtccacgccacactcccagagagcggcctgacgcaccgcatcaggggccttttcgagagcgctgtacagagcgaggatggcgagcagtgtcccctgctgtggaggatgtatctgaagttcctggtttccttaggaaataaggaaaggagcaaaggtgtgttctacaaggcacttcagaactgcccatgggcgaaggcactgtacatggacgcagtggagtacttcccggatgagatacaggaaatcctagacctgatgaccgagaaggagctccgggtgcgcctgccactggaggaactggatctcctgcttgaggactaggtagcaggctggagtgcagtgcagctgcagatgagacaagacagagagatgggcagatggggtcc

//