LOCUS       XM_046063439            3028 bp    mRNA    linear   VRT 05-MAR-2022
DEFINITION  PREDICTED: Micropterus dolomieu dicer 1, ribonuclease type III
            (dicer1), transcript variant X3, mRNA.
ACCESSION   XM_046063439
VERSION     XM_046063439.1
DBLINK      BioProject: PRJNA800460
KEYWORDS    RefSeq.
SOURCE      Micropterus dolomieu (smallmouth bass)
  ORGANISM  Micropterus dolomieu
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Neoteleostei;
            Acanthomorphata; Eupercaria; Centrarchiformes; Centrarchoidei;
            Centrarchidae; Micropterus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_060160) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI
            Annotation Status           :: Full annotation
            Annotation Name             :: Micropterus dolomieu Annotation
                                           Release 100
            Annotation Version          :: 100
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 9.0
            Annotation Method           :: Best-placed RefSeq; Gnomon
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3028
                     /organism="Micropterus dolomieu"
                     /mol_type="mRNA"
                     /isolate="WLL.071019.BEF.003"
                     /isolation_source="freshwater lake"
                     /db_xref="taxon:147949"
                     /tissue_type="fin"
                     /ecotype="Adirondacks"
                     /geo_loc_name="USA: Adirondacks, Woodhull Lake"
                     /lat_lon="43.598747 N 74.970827 W"
                     /collection_date="2019-07-10"
                     /linkage_group="LG11"
     gene            1..3028
                     /gene="dicer1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Gnomon. Supporting evidence
                     includes similarity to: 4 Proteins, and 99% coverage of
                     the annotated genomic feature by RNAseq alignments,
                     including 7 samples with support for all annotated
                     introns"
                     /db_xref="GeneID:123979502"
     CDS             401..3028
                     /gene="dicer1"
                     /codon_start=1
                     /product="endoribonuclease Dicer isoform X2"
                     /protein_id="XP_045919395.1"
                     /db_xref="GeneID:123979502"
                     /translation="

MAGLQLVTPATSPMGPFFGLPWQQEAIHDNIYTPRKYQVELLEAALEHNTIVCLNTGSGKTFIAVLLTKELSHQIRGHYQENAKRTVFLVNTALCVVQQAAAVRTHSDLQVGEYTDLEETSAWTDQQWNQEIIENQVLVMTCHIFLHVLKNKILQLSKINLVVFDDCHLAITDHPYCEIMKLFEGCSCSPRILGLTASILNGKCDPSELEQKIQNLERILKSNAETATDLVVLDRYASQPREVVLDCGPYLDKSGLSSHLQTELDEALLFLNDCNISVAKDERDPTFISKQVLSDCRAVLQVLGPWCADKAAGIMVRELQKYIKHEQEELNRKFLLFTDTILRKVHALCEEHFSPASLDLKFVTPKVLRLLEILHEYKPFERQQFESVEWYNNRNQDNYVSWSDSEDEDEDEEVEAKERPEANFPSPFTNILCGIIFVERRYTAVVLNRLIKEAGKQDPELAYISSNFITGHSIGKNQLRNKQMEVEFRKQEEVLRKFRAHETNLLIATSIVEEGVDIPKCNLVVRFDLPTEYRSYVQSKGRARAPVSNYIMLADSERTKAFEEDLTTYKAIEKILRNKCSKTMEVSEFEVEQVLDDDNILPPYVLRSEDGGPRVTINTAIGHINRYCARLPSDPFTHLAPKCKTKEMQDGRFQSTLYLPINSPLRVPVKGPTMNCARLAEKAVALVCCEKLHKIGELDDHLMPVGKETVKYEEELDLHDEEETSVPGRPGSTKRRQCYPKAIPECLRDSYAFPEQTYYLYVIGMVLTTPLPDELNFRRRKLYPPEDTTRCFGILTAKPIPRIPHFPVYTRSGEVTISIELQKSGFTLTAAQLDLITRLHQYIFSHILRLEKPALEFKPTLADSAYCVLPLNVGE"

     misc_feature    494..1087
                     /gene="dicer1"
                     /note="DEXH-box helicase domain of endoribonuclease Dicer;
                     Region: DEXHc_dicer; cd18034"
                     /db_xref="CDD:350792"
     misc_feature    order(494..505,512..514,563..586,707..709,896..898,
                     989..991)
                     /gene="dicer1"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:350792"
     misc_feature    order(671..676,743..748,821..823,827..832,839..841,
                     914..922)
                     /gene="dicer1"
                     /note="nucleic acid binding site [nucleotide binding];
                     other site"
                     /db_xref="CDD:350792"
     misc_feature    1181..1465
                     /gene="dicer1"
                     /note="Partner-binding domain of the endoribonuclease
                     Dicer; Region: Dicer_PBD; cd15903"
                     /db_xref="CDD:277191"
     misc_feature    order(1196..1201,1208..1210,1214..1219,1394..1399,
                     1406..1411,1418..1420,1427..1432,1439..1441)
                     /gene="dicer1"
                     /note="Trbp binding interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:277191"
     misc_feature    1679..2062
                     /gene="dicer1"
                     /note="C-terminal helicase domain of the endoribonuclease
                     Dicer; Region: SF2_C_dicer; cd18802"
                     /db_xref="CDD:350189"
     misc_feature    order(1715..1723,1931..1933,1988..1990,1994..1996)
                     /gene="dicer1"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:350189"
     misc_feature    order(1943..1945,1949..1951,2024..2026,2030..2032)
                     /gene="dicer1"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:350189"
     misc_feature    2258..2524
                     /gene="dicer1"
                     /note="Dicer dimerization domain; Region: Dicer_dimer;
                     pfam03368"
                     /db_xref="CDD:460900"
ORIGIN      

tttacgttaatgttttggcgtagcagaggcccaggtgaaaggaagtggtcccaccgaggacgaatagccaccaaatcgggacagcaagagtgactggaaatgaggacatccaacgaatgatttcaagtatttttagccaagacgatcaattgtaaaacataaatcagggctggaggaaccagcacaatccctgccactttgcatttgtgtagaggtcttaaatgtgggggaacatcggaagttgattaagagatattttattatgaagcccagattacgtgttttctgtttatccagaaagtttcaattgttaccttgaacttctgaaacaactaggatgaagaaatgagataaagtggacgactggaggagcccagcctcacctccaactctttgaagcatggcaggcctacagcttgttacccctgccacttcacccatggggcctttctttggtctgccatggcagcaggaggctatccatgataacatctatacccctaggaaatatcaggtagaacttcttgaagcagctcttgaacataatactatcgtctgcttaaataccggctcagggaagacctttattgcagtacttcttacaaaagagctctcccaccaaatccgcggacattaccaagaaaatgcaaagaggacagtttttctggtgaacacagcgttgtgtgtagttcagcaagcggctgcagtcaggactcactctgacctccaggtgggagagtacacagatttggaggagacctcagcatggactgaccaacagtggaatcaagagataatcgagaatcaggttctggtcatgacgtgccacatattcttacatgttctgaagaataaaatcttacagttgtctaaaatcaacctggtggtttttgatgattgtcacctggctatcacagaccacccctactgtgagataatgaagctgtttgagggctgctcttgcagtcctcgtatcctgggtctcacagcatccattctgaatggaaagtgtgacccatcagaactggagcagaagatccagaatctggagagaatcctgaagagcaacgctgaaactgccactgatcttgtggtcctggacagatacgcctctcagccaagagaagtggtactggactgtggcccctacttggataagagtggcctctcctcccatctgcagacggagctggatgaagctctcctcttcctgaacgattgcaacatatctgttgccaaagacgagcgtgatcccacattcatctccaaacaggtcctgagtgactgtcgggccgtgctgcaggtgctggggccctggtgtgcggataaagctgcgggcatcatggtgcgggagctccagaagtacatcaaacatgagcaagaggagctcaaccgcaagtttctgctcttcaccgataccatcctgcgcaaagtgcatgccctctgcgaggagcacttctcccccgcctcgctggacctcaagttcgtcacccccaaggtcctcaggctgctggagatcctgcacgaatacaagcccttcgagcggcagcagtttgaaagtgtagagtggtataacaaccgcaaccaggacaactacgtgtcctggagcgactctgaggatgaagatgaggatgaggaggtggaggccaaagagaggcctgaagccaattttccctctccattcaccaacatcctgtgtgggatcatcttcgtggagaggcgttacacagctgtcgtcctcaatcgtctgatcaaagaggcagggaagcaggacccagagctggcttacatcagcagcaacttcatcactggccacagcatcggcaagaaccagctacggaacaagcaaatggaggtggagttcaggaaacaagaggaggttcttcgcaaattcagggctcatgaaactaacctgctgatcgccaccagcatcgtcgaggaaggcgtggatattccaaagtgtaacctggtggtgcggtttgacttgcccacagagtacaggtcctacgtccagtccaaaggcagagctcgggcacctgtctccaactacatcatgctggctgacagtgagaggaccaaagccttcgaggaagatctcactacctacaaggccatagagaagatcttaaggaacaagtgctctaagacaatggaggtgagtgagtttgaagttgagcaggtgctggatgatgacaacatcctcccgccctatgtgcttcgatctgaggatggaggtccccgggtcaccatcaacacagccatcggacacattaacaggtattgtgctcggcttcccagtgacccgttcacccacttggcacctaagtgtaaaactaaggagatgcaggacggacgtttccaatccacactctatttacccatcaattcccctctgcgagttcctgttaagggtcctacgatgaactgtgccagactggcagagaaagcagttgcactagtgtgttgtgagaaactccacaaaataggtgagctggatgatcacctgatgccggtaggaaaggagaccgtgaagtatgaggaggagctggaccttcatgatgaggaggagacgagcgtaccaggcaggcccggctctaccaagaggaggcagtgctaccctaaagccataccagagtgtctgcgggacagttacgctttcccggagcagacttactacctatatgtgattgggatggtcctcaccacccctctccctgatgaactcaacttccgcagaaggaaactctaccccccggaggacaccaccaggtgcttcggcatactgactgccaaacccatacctcgaatcccccatttcccagtgtacactcgctcgggtgaggtgaccatctccattgagctgcagaagtctggcttcacactcaccgctgcccagctcgacctcatcacccgcctgcaccagtatattttctcccatatcctccgcctagagaaacctgcactggagttcaagcccacgctggccgactcggcttactgcgttctacctctgaatgttggtgagtag

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