LOCUS       XM_040710363            3010 bp    mRNA    linear   INV 12-MAR-2025
DEFINITION  PREDICTED: Lepeophtheirus salmonis protein argonaute-2 (AGO1),
            mRNA.
ACCESSION   XM_040710363
VERSION     XM_040710363.2
DBLINK      BioProject: PRJNA687570
KEYWORDS    RefSeq.
SOURCE      Lepeophtheirus salmonis (salmon louse)
  ORGANISM  Lepeophtheirus salmonis
            Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Crustacea;
            Multicrustacea; Hexanauplia; Copepoda; Siphonostomatoida;
            Caligidae; Lepeophtheirus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_052134) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Mar 12, 2025 this sequence version replaced XM_040710363.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_016086655.4-RS_2025_03
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 03/04/2025
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3010
                     /organism="Lepeophtheirus salmonis"
                     /mol_type="mRNA"
                     /db_xref="taxon:72036"
                     /chromosome="4"
     gene            1..3010
                     /gene="AGO1"
                     /note="protein argonaute-2; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 1678
                     long SRA reads, 46 Proteins"
                     /db_xref="GeneID:121116133"
     CDS             209..2887
                     /gene="AGO1"
                     /codon_start=1
                     /product="protein argonaute-2"
                     /protein_id="XP_040566297.1"
                     /db_xref="GeneID:121116133"
                     /translation="

MYPGGQTPTAGGGLVVPNLGPMIATTTTGAGGGSSGEATTAPSPPFMLPGGDAPIFVCPRRPNIGKEGKHIMLKANHFQITMPRGFIHHYSVSITPDKCPRKVNREIIETMVHSYSKIFGTKKPVFDGRSNLYTRDPLPIGQESMELEVTLPGEGKDRVFRVAVKWNAQVSLYALEEALEGRSRQIPFDAIQALDVVMRHLPSMTYTPVGRSFFSSPEGYYHPLGGGREVWFGFHQSVRPSQWKMMLNIDVSATAFYKAQPVIDFMCEVLDIRDINDQRKPLTDSQRVKFTKEIKCLKIEITHCGSMRRKYRVCNVTRRPAQMQSFPLQLDNGQTVECTVSKYFLDKYKMKLRNPHLPCLQVGQEHKHTYLPLEVCNIVQGQRCIKKLTDMQTSTMIKATARSAPDREREINNLIRKADFNNDPYVQEFGLNISHDLMEVRGRVLPPPKLQYGGRTKQQALPNQGVWDMRGKQFFTGVEIREWAIACFAPSRTVREDALRNFTQSLQKISNDAGMPIIGQPCFCKYANGPDQVEPMFRYLKATFAGLQLIVVVLPGKTPVYAEVKRVGDTVLGMATQCVQAKNVNKTSPQTLSNLCLKINVKLGGVNSILVPSIRPKVFNEPVIFLGADVTHPPAGDNKKPSIAAVVGSQDAHPSRYAATVRVQAHRVEIIQELSTMVKEHLMMFYKSTGGYKPHRVIIYRDGVSEGQFLQVLQHELTAIREACIKLETDYKPGITFIVVQKRHHTRLFCSDKKEQSGKSGNIPAGTTVDIGITHPTEFDFYLCSHQGIQGTSRPSHYHVLWDDNHFAADELQCLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVEKEHDSGEGSHLSGGSEDRAPAAMARAVTVHADTRKVMYFA"

     misc_feature    578..802
                     /gene="AGO1"
                     /note="N-terminal domain of argonaute; Region: ArgoN;
                     pfam16486"
                     /db_xref="CDD:465134"
     misc_feature    830..982
                     /gene="AGO1"
                     /note="Argonaute linker 1 domain; Region: ArgoL1;
                     pfam08699"
                     /db_xref="CDD:462567"
     misc_feature    983..1345
                     /gene="AGO1"
                     /note="PAZ domain, argonaute_like subfamily. Argonaute is
                     part of the RNA-induced silencing complex (RISC), and is
                     an endonuclease that plays a key role in the RNA
                     interference pathway. The PAZ domain has been named after
                     the proteins Piwi,Argonaut, and Zwille; Region:
                     PAZ_argonaute_like; cd02846"
                     /db_xref="CDD:239212"
     misc_feature    order(1139..1141,1184..1186,1226..1228,1238..1240,
                     1292..1294,1313..1315,1319..1321)
                     /gene="AGO1"
                     /note="nucleic acid-binding interface [nucleotide
                     binding]; other site"
                     /db_xref="CDD:239212"
     misc_feature    1478..2758
                     /gene="AGO1"
                     /note="PIWI domain, Argonaute-like subfamily. Argonaute is
                     the central component of the RNA-induced silencing complex
                     (RISC) and related complexes. The PIWI domain is the
                     C-terminal portion of Argonaute and consists of two
                     subdomains, one of which provides the...; Region:
                     Piwi_ago-like; cd04657"
                     /db_xref="CDD:240015"
     misc_feature    order(1889..1891,1901..1903,1937..1948,1955..1957,
                     1979..1981,1988..1990,2000..2002,2012..2014)
                     /gene="AGO1"
                     /note="5' RNA guide strand anchoring site [active]"
                     /db_xref="CDD:240015"
     misc_feature    order(2093..2095,2099..2101,2312..2314,2726..2728)
                     /gene="AGO1"
                     /note="active site"
                     /db_xref="CDD:240015"
     polyA_site      3010
                     /gene="AGO1"
                     /experiment="COORDINATES: polyA evidence [ECO:0006239]"
ORIGIN      

gagaggagactttggtttagagagggagaagtataaagagagagagagagagcgtgagtgagtgagtgagtgtgtgttcttcttttcccttctttccttttttcctctcttttcttttctttctcctgctatctgtggcctgtgagtagctcttatttgtgttgaagaggagaatccgctccttggacttaattactaaatagccggaatgtatcccggtggacagacccctactgcgggaggcggactcgttgtgcccaatttaggtcccatgatcgcgacaacgacaactggagctggcggcggttcttcaggggaagcaacaacagctccttctccaccctttatgcttccgggaggcgatgcgccgatcttcgtgtgcccgcggagacccaacattgggaaggaagggaagcatatcatgctgaaagccaaccatttccagatcacgatgcctcgcgggttcattcaccactacagcgtgtccatcaccccagacaaatgccctcgcaaggtgaaccgggaaatcatcgaaaccatggttcactcctactcgaagatcttcggaacgaagaagcccgttttcgatggtcgtagcaatctctatacccgtgatcctctgcccattggacaagagtccatggagcttgaagtgactcttccgggtgagggtaaagatcgtgtgttccgcgttgctgtgaaatggaacgcacaagtctcgctctacgccctagaagaagctctggaagggcgctcgcgtcaaattccctttgatgcgattcaagctcttgacgtagtcatgcgacatcttccctccatgacctatacacctgttggccgctcattctttagttcacctgaaggttactatcatccccttggaggagggagagaagtctggttcgggtttcatcaaagtgttcgtccatcgcaatggaaaatgatgttgaacattgatgtgagtgctacggctttctacaaggctcaacccgttattgatttcatgtgtgaagtccttgacatacgcgatattaatgatcaacgtaaaccactcaccgactctcaacgggttaaatttactaaagaaatcaaatgtctcaaaatcgaaattacacattgtggaagtatgcgccgtaaatatcgggtttgcaacgtaacacgacgtccagctcaaatgcaaagcttccctttgcaattggataacggccagactgtggagtgcactgtgagcaaatatttcttagataagtacaagatgaagttaaggaatcctcatttaccttgtctccaagtgggtcaagaacataaacacacctatttacctttggaagtttgtaacattgtccagggccagagatgcataaaaaaattgacggatatgcaaacttctactatgattaaggcaactgcacgctcagctccagaccgagaaagagagattaataatttaattaggaaggcagattttaataatgatccatatgtacaagagtttggactgaatataagtcatgatctgatggaggtcagaggtcgcgttcttcctcctccaaaacttcagtatggaggtagaacaaagcaacaagcactaccaaatcaaggcgtgtgggacatgagaggtaaacagtttttcactggtgttgaaattcgagaatgggccattgcttgttttgctccatcacgcactgttcgagaggatgctctccgcaattttacacaatcacttcagaaaatatctaacgatgccggaatgccaataataggacaaccttgtttttgtaaatatgcaaatggccctgatcaagttgagcctatgtttcgatacctgaaagctacctttgcaggattgcaattgatagttgttgttttacccggaaaaacccctgtttatgctgaagtgaaaagagttggagacactgtacttggaatggctacacaatgtgtacaagccaaaaacgtcaacaagacatcacctcaaactctttcaaatctttgtctaaagattaatgttaaattagggggtgtcaacagcattctcgttcccagtattcgacctaaagtgtttaatgaacctgttatattccttggagctgatgtaactcatcctccagctggtgacaacaaaaaaccatccattgctgcggttgttggttctcaagatgctcatccatctcgctatgctgctactgtccgtgttcaagcccatcgtgttgaaattatccaagaacttagcaccatggtaaaagaacatttaatgatgttctacaagtcaacaggaggctataagccacatagagtcattatttatagagatggagtttctgaaggccaattcctacaagttttacaacatgaactgacggctattcgtgaagcttgcatcaaattagaaacggattataaaccagggataactttcattgttgtgcaaaagcgtcatcatactcgtttgttttgttcagacaagaaagagcaatctggaaagtctggtaatattcctgctggtactaccgttgatattggaatcactcatcctacggagttcgacttttatctctgttctcatcaaggtattcagggtacatctcgaccttcgcattatcatgtcttatgggatgacaatcattttgctgcagatgagctccaatgtctcacgtatcagctttgccacacttatgtccgatgtactcgctccgtctctattccagccccggcctattatgctcatcttgtggctttccgggctcgatatcatcttgtagaaaaagagcacgactcaggtgaaggctctcatctctctggtggctctgaggatagagctcctgcagctatggcgcgtgctgtcacggttcatgctgacactcgaaaagtcatgtactttgcataaaaagtacaatcaattaattattataatcactattaagaacctatagaatcatcttctttaaaaaaaaatatgagtctgtcgaatatttcagcaatctctctttctcccctatgatcaagaaaa

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